This week: The medicinal chemistry of dengue virus, natural products as sources for new drugs, dramatic seasonal shifts in groundwater arsenic– and more! Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of […]

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This week: The medicinal chemistry of dengue virus, natural products as sources for new drugs, dramatic seasonal shifts in groundwater arsenic– and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!

Selective Imaging of Malignant Ascites in a Mouse Model of Peritoneal Metastasis Using in Vivo Dynamic Nuclear Polarization-Magnetic Resonance Imaging

Hinako Eto, Fuminori Hyodo, Kenji Nakano, and Hideo Utsumi

DOI: 10.1021/acs.analchem.5b04821

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Natural Products as Sources of New Drugs from 1981 to 2014

David J. Newman and Gordon M. Cragg

DOI: 10.1021/acs.jnatprod.5b01055

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Soluble Dinaphtho[2,3-b:2′,3′-f]thieno[3,2-b]thiophene Derivatives for Solution-Processed Organic Field-Effect Transistors

Masanori SawamotoMyeong Jin KangEigo MiyazakiHiroyoshi SuginoItaru Osaka, and Kazuo Takimiya

DOI: 10.1021/acsami.5b10477

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Aquifer Arsenic Cycling Induced by Seasonal Hydrologic Changes within the Yangtze River Basin

Michael V. Schaefer, Samantha C. Ying, Shawn G. Benner, Yanhua Duan, Yanxin Wang, and Scott Fendorf

DOI: 10.1021/acs.est.5b04986

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Discovery of 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma

jm-2015-01653z_0021
jm-2015-01653z_0021

Mira A. M. Behnam, Christoph Nitsche, Veaceslav Boldescu, and Christian D. Klein

DOI: 10.1021/acs.jmedchem.5b01653

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