March 2016 - ACS Axial | ACS Publications

Kai Rossen Talks about the Evolution of Organic Process Research & Development


Now in its 20th year of publication, Organic Process Research & Development (OPR&D) is experiencing an evolution. Dr. Kai Rossen, who became Editor-in-Chief of the journal at the beginning of 2015, is working together with Associate Editor Dr. Qilong Shen to position OPR&D to better reflect recent changes within the broad field of industrial process chemistry.

Rossen is a group leader at Sanofi in Frankfurt, Germany, where he has worked since 2005. He brings with him nearly 30 years of experience in industry and an exciting vision for where OPR&D is headed. Shen has been a Professor at the Shanghai Institute of Organic Chemistry since 2010.

One of the changes introduced to the journal this year is a new cover and logo. Rossen said the new look—”OPR&D” in large, green letters, with the full journal title and complementary green background—is a visual representation of the changes in the industry and the scope of the journal itself.

“To some extent, the old logo was fine, but the cover had a picture of a kilo lab, which is just a small part of the overall business. And I think it’s difficult to find a single picture, a single element that describes the very wide subject area of Organic Process Research & Development, now consistently referred to as OPR&D. While it is a catchphrase, green chemistry—the attempt or the need to do chemistry in a sustainable manner—should be reflected in the color, and this is why we have forest green as a primary color for branding,” he said.

The Editorial Advisory Board has seen some changes, too. Rossen said the board is now more geographically and topically diverse. “We have a lot more academic members in the Editorial Advisory Board, because, clearly, the journal is interested in getting practically-applicable academic research published as well. And so the Editorial Advisory Board is trying to reflect the wider geographic distribution of high-quality science today,” he said.

Readers of OPR&D come from academia and industry, including pharmaceuticals and green chemistry. Rossen said students and others in academia read the journal to get a better understanding of important findings from the industrial arena, with an interest in seeing how basic chemistry is applied, and this is a connection that Rossen seeks to amplify.

“I would like to have the journal serve as a bridge between academia and industry, because there is a lot of research going on that is of value for practical applications. And having that work published in the journal is something that I’m really keen on, and we’ve had some very, very nice success stories lately,” Rossen said.

One of the journal’s strengths is in its reviewers, many of whom are industrial chemists and know the right questions to ask, he said. It’s these people that help academic researchers scale up their work to make it more viable for use at an industrial level.

Chemical industry has changed in the decades since OPR&D was first launched, with increased emphasis on collaboration, and funding prospects that are continually in flux. However, many things, like the core of the work and the mentality of the industry, remain very close to what they were 20 years ago. OPR&D is evolving with the community, and is well-positioned to meet the needs of its authors, reviewers, and readers with Rossen at the helm.

Watch Dr. Rossen’s new editor video on his vision for OPR&D:

Get the Scoop on Innovations in Alternative Fuels

2016-material-series-chemistry-of-goWhat chemical discoveries have had the biggest impact on our everyday lives? In 2016, the American Chemical Society is bringing you eleven webinars divided into 4 different modules that will highlight the innovations in materials science that have touched millions of people and reshaped industries. Join us on the first Thursday of every month to meet with some of the materials science industry’s leading minds, and ask your questions.

April’s Webinar: Chemistry of Go: Innovations in Alternative Fuels

The evolution of novel technologies in the alternative fuels space is not for the faint-hearted. Jennifer Holmgren, the CEO of LanzaTech will cover the challenges involved when scaling innovations from the lab to the marketplace. Drawing on her experience at UOP (a Honeywell company) and her current role at carbon recycling company LanzaTech, Jennifer will lay out how industry is creating new ways to fuel our lives.

Join us for this free webinar and you’ll learn:

  • Success requires technologies that move beyond a ‘one size fits all’ approach and are able to scale and deploy in a variety of situations.
  • Cross-sector commercial and research partnerships help fuel the innovation necessary to enable us to meet our global energy challenges.
  • Balancing the discipline required in scaling with the risk of speed is key to success


  • Date: Thursday, April 7, 2016 @ 2-3pm ET
  • Fee: Free to Attend
  • Download Slides: Available Day of Broadcast


Jennifer Holmgren

Mark Jones
Dow Chemical

C&EN Roundup: Detecting Antibodies, Improving Batteries and Testing Beer

Chemical & Engineering News covers the world of chemistry, from research and education to business and policy. Here’s a sampling of their coverage of research from ACS journals:


New Test May Be Able to Detect Antibodies in Saliva

Detecting antibodies for a given illness can be a useful way of diagnosing a patient, but even the gold standard antibody test, an enzyme-linked immunosorbent assay, doesn’t always work. Now researchers have developed a polymerase chain reaction test for antibodies that’s 1,000 times as sensitive as ELISA. The new test could have a major impact in public health circles since it may be sensitive enough to detect antibodies via a quick, simple saliva test that could be administered in developing areas.



Reducing Mechanical Strain May Help Improve Battery Performance

New research into how mechanical strain hinders the performance of battery cathodes could provide insights into that creation of more efficient power storage. The lithium-ion batteries used in power tools and certain kinds of cars need to be able to deliver power in quick bursts, but these switches place strain on a battery’s cathode, degrading its performance.  Researchers used intense X-rays to study how charges and discharges strain battery material, information that could one day help develop batteries designed to better withstand the strain of frequent switches.



Catalyst Could Prove Financial Boon to Biorefineries

Elephant grass can be converted into an alternative fuel source, but doing so requires stripping out a polymer called lignin. Now researchers have found a low-cost nickel-based catalyst capable of converting the majority of that lignin into valuable aromatic compounds. The breakthrough could help biorefineries become more economically viable by allowing them to sell these value-added compounds.



Computational Model Could Help Spot Liver-Damaging Drugs Ahead of Trials

Before a new drug can be tested on humans, researchers must figure out if the new compound is likely to cause liver damage, which can be tricky since liver damage sometimes manifests after years of exposure. A new computational model could make this task simpler by comparing the new drug to other compounds known to cause liver damage. The new model relies on a much larger database than previous attempts and allows for inconclusive results, rather than labeling all compounds as either safe or unsafe.



Smartphone Test Measures Beer Freshness With Brewery-Level Accuracy

It is now possible to test beer’s freshness using nothing but a smartphone and a color-changing film. The test uses a smartphone app to evaluate a test disc of polymer film that detects concentrations of furfural, a compound that forms when beer is heated and gives the beverage an unpleasant taste. While the test is simple enough to perform at home, it is more likely to be used by manufacturers looking to spot-check a batch of beer right before shipping.



That’s just a small sample of the robust coverage C&EN provides. Get the latest news in your discipline with weekly e-mail updates.


9 Promising Young Scientists Join Nano Letters’ Early Career Advisory Board

The future of science perennially belongs to the next generation. Students and young professionals are continual sources of enthusiasm, determination, and new ideas. To maintain their relevance for generations to come, scientific publications must find ways to engage scientists early in their careers. Journals can help provide guidance, as well as receive critical feedback from new readers. That’s why Nano Letters is expanding its newly created Early Career Advisory Board.

Meet the newest members of the Early Career Advisory Board:

Katherine Jungjohann is a staff scientist at Sandia National Laboratory’s Center for Integrated Nanotechnologies. Her research focuses on liquid-phase TEM of nanomaterial growth, assembly, corrosion & electrochemistry.


Matthew McDowell is an assistant professor at Georgia Tech. McDowell’s group seeks to understand & control multi-scale dynamic processes in electrochemical materials.


Keith A. Brown is an assistant professor of Mechanical Engineering, Materials Science & Engineering and Physics from Boston University. His group’s research focuses on confining soft materials at the nanoscale and studying how they behave.


Sarah Brittman, is a postdoctoral researcher at FOM Institute AMOLF in Amsterdam, the Netherlands. Brittman seeks to understand & control materials at the nanoscale to create new and better optoelectronic devices.


Haotian Wang is a Rowland Junior Fellow at the Rowland Institute at Harvard Univertsity. Wang’s research interests focus on developing highly efficient catalysts for renewable energy applications.


Jingshan Luo is a postdoctoral fellow at École Polytechnique Fédérale de Lausanne.

Jingshan’s research focuses on solar energy conversion and electrocatalysis.


Benjamin Isaacoff is an applied physics graduate student at The University of Michigan. Ben’s research focuses on exploring the interaction of single fluorescent molecules & plasmonic antennas.


Betty Kim is a neurosurgeon scientist who serves as Assistant Professor of Neurosurgery, Neuroscience and Cancer Biology at the Mayo Clinic. Kim’s group seeks to understand mechanisms of nano-immune interactions in vivo & develop therapies for brain tumor patients.


Umberto Celano is a researcher in the Material & Component Analysis Lab at imec, Belgium. Umberto’s research at imec focuses on novel 3D metrology concepts for the analysis of emerging electronic devices.


New members were elected to the Early Career Advisory Board after a call for nominations period in late 2015. Nominations were open to graduate students, postdocs, and early career faculty in their first three years as an Assistant Professor or similar position in industry or national laboratories.

Get an Update on the Response to Zika Virus

Zika virus has long been known to the infectious disease community, but until the current outbreak, scant research had been conducted to understand the virus or how to combat it. The sudden explosion in infections—and the increasingly strong evidence that it can cause microcephaly in babies born to women infected while pregnant—has thrust Zika virus into the scientific spotlight.

This webinar, brought to you by ACS Infectious Diseases,  will highlight the current scientific efforts being made to contain this outbreak and prevent future spread of Zika virus. Specifically, the focus of the webinar will be on the NIH response to the outbreak, vaccine development efforts from the pharmaceutical industry, and basic science research on Zika virus from an academic perspective.

During this free webinar you will learn:

·       The NIH response to the Zika virus outbreak
·       The Zika virus vaccine development efforts from Sanofi Pasteur
·       The role of academic research in Zika virus response

Webinar Speakers

MorensDavid M. Morens, M.D.
CAPT, United States Public Health Service, Senior Advisor to the Director
National Institute of Allergy and Infectious Diseases
National Institutes of Health
headshot_J._HeinrichsJon Heinrichs, Ph.D.
Associate Vice President,
Segment Head Sanofi Pasteur
Shi,_Pei-YongPei-Yong Shi, Ph.D.
I.H. Kempner Professor of Human Genetics,
Department of Biochemistry & Molecular Biology,
University of Texas Medical Branch,
ACS Infectious Diseases Associate Editor

The webinar will be held Thursday, April 14 at 11 AM EDT.

Reserve your place at this webinar today!



ACS Editors’ Choice: Self-Healing Water Treatments, Fighting Antibiotic-Resistant Bacteria — and More!

This week:  a self-healing water treatment membrane, a new tool to combat antibiotic-resistant bacteria, benchmarking in catalysis research– and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!


Critical Evaluation of Published Algorithms for Determining Environmental and Hazard Impact Green Metrics of Chemical Reactions and Synthesis Plans

ACS Sustainable Chem. Eng., Article ASAP
DOI: 10.1021/acssuschemeng.5b01555



Synthesis and Shuttling Behavior of [2]Rotaxanes with a Pyrrole Moiety

J. Org. Chem., Article ASAP
DOI: 10.1021/acs.joc.5b02911



Dipeptide-Based Metabolic Labeling of Bacterial Cells for Endogenous Antibody Recruitment

ACS Infect. Dis., Article ASAP
DOI: 10.1021/acsinfecdis.6b00007



Triboelectric Nanogenerator as a Self-Powered Communication Unit for Processing and Transmitting Information

ACS Nano, Article ASAP
DOI: 10.1021/acsnano.5b07407


Toward Microcapsule-Embedded Self-Healing Membranes

Environ. Sci. Technol. Lett., Article ASAP
DOI: 10.1021/acs.estlett.6b00046


Toward Benchmarking in Catalysis Science: Best Practices, Challenges, and Opportunities

ACS Catal., 2016, 6, pp 2590–2602
DOI: 10.1021/acscatal.6b00183


Designing an Antibody-Based Chaperoning System through Programming the Binding and Release of the Folding Intermediate

ACS Chem. Biol., Article ASAP
DOI: 10.1021/acschembio.6b00191


Love ACS Editors’ Choice? Get a weekly e-mail of the latest ACS Editor’s Choice articles and never miss a breakthrough!

Which Fictional Chemist Are You?

The annals of classic literature and pop culture are full of fascinating fictional scientists, from the heroes like Tony Stark to mad geniuses like Dr. Frankestein. Which one do you resemble most? There’s only one way to find out. Take our quiz and find out!

Did we leave your favorite fictional chemist off our list? Let us know in the comments.

ACS Central Science Celebrates Its First Anniversary

ACS Central Science – our first fully open access journal – celebrates its first birthday this week. It was one year ago, at the ACS spring meeting in Denver, that the journal debuted. Today ACS Central Science is living up to its promise to highlight and communicate research articles that epitomize the “centrality of chemistry.” Every issue of the journal has also featured an array of news, features and mini-reviews, including an exciting collaboration with C&EN contributing reporters.

The journal marked its first anniversary with a symposium at the 2016 spring meeting in San Diego, featuring Josh SwamidassAshley SpiesThomas Miller IIINuria Lopez and  Alán Aspuru-Guzik, not to mention a little celebratory cake.

Editor-in-Chief Carolyn Bertozzi penned an editorial in honor of the occasion, “Happy Birthday, ACS Central Science!” Bertozzi is an ardent champion of open science, and she drives that point home here, writing:

“Unlike any multidisciplinary chemistry journal before us, right from day one we made ACS Central Science, designed to publish the best research, wholly open access and freely available to readers and authors. See an article of interest in our Twitter feed? Click on it and you are in—no subscription fees, VPN gymnastics or institutional affiliations necessary. This is a convenience for people like me, but essential for our readers who work in settings lacking resources for journal access and for citizens who are not scientists but want to learn more about how chemistry impacts their everyday lives. In this regard, ACS Central Science can be a powerful vehicle for elevating the visibility of chemistry in the world at large.”

Bertozzi celebrates the variety of research appearing in ACS Central Science. The journal is home to both genre-defying interdisciplinary studies marrying very different fields of chemistry as well as ground-breaking papers in core chemistry subjects. She also has positive things to say about the publishing enterprise:

“The journal’s first year of publication was also my first as an Editor, a personally and professionally enriching experience that I continue to embrace with gusto. Work in the trenches of scientific publishing stretches your brain in all kinds of new directions. I learned more chemistry reading a year of ACS Central Science submissions than in the three decades prior. Some of this newfound knowledge has infiltrated the classes I teach. I met more people from more diverse backgrounds—ACS staff, other editors, publishers, writers and reporters, as well as scientists around the globe—than any academic job could deliver. The experience has also tuned me in to professional opportunities that can benefit my students and postdocs, both past and present. I was surprised by how much there is to learn about publishing, even after one has published hundreds of papers from the other side of the table.”

We wish Carolyn and everyone involved with ACS Central Science a happy first birthday.

New Lipstick Analysis Method Could Help Catch Criminals

You know that scene in your favorite police procedural where the detective finds a tiny lipstick sample on a napkin or a shirt collar and sends it off to the lab for analysis? On TV the sample comes back in a flash and the culprit is always wearing some exotic brand of lipstick that makes it easy to place them at the scene of the crime. In real life, those kinds of lab tests are slow, expensive and often inconclusive. Or at least they used to be.

Brian Bellott of Western Illinois University says he’s found a better way to do lipstick analysis. His method is simple enough for a graduate student to perform and use gas chromatography to identify unique compounds in 40 different lipstick brands. Bellot says this method requires no specialized equipment or training to perform. His lab is working to increase the number of lipstick samples on file.

Watch this video to learn more:

Watch Bellot talk about his research during the 251st ACS National Meeting:

Watch more great ACS videos.

3-D Printing Tech Could Someday Make Replacement Ears a Reality

Athletes, the elderly and others who suffer from injuries and arthritis can lose cartilage and experience a lot of pain. Cartilage is a tissue which has very poor regenerative potential. Researchers are now reporting in Biomacromolecules, however, that they found a way to produce the “rubbery”  cartilage tissue with 3-D bioprinting and human cells that produce cartilage. The researchers say they have successfully confirmed their findings via an in vivo mice model. The development could one day lead to precisely printed implants to heal damaged noses, ears and knees.

Watch and learn more:

The researchers presented their work at the 251st National Meeting & Exposition of the American Chemical Society:

Watch more great ACS videos.