February 2017 - ACS Axial | ACS Publications

You Are Invited to ACS Measurement Science Journals Reception at Pittcon 2017 in Chicago

If you are attending Pittcon 2017 (The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy) in Chicago this year, you will not want to miss the ACS Measurement Science Journals Reception on March 6, 2017 at Hyatt Regency McCormick Place. It’s your opportunity to meet the editors of ACS Sensors, Analytical Chemistry, and Journal of Proteome Research! You will also receive Free gifts sponsored by the journals while networking with the top scientists from around the world. Be sure to RSVP today!

Watch this video invitation from our editors-in-chief.

Date: March 6, 2017, 5 – 7 pm
Location: Hyatt Regency McCormick Place, meeting room Grant Park BCD

See you there!

C&EN Roundup: Improving Antifungal Medication, Sodium-Ion Batteries, and Time-Release Fertilizer

Chemical & Engineering News covers the world of chemistry, from research and education to business and policy. Here’s a sampling of their coverage of research from ACS journals:

Reducing the Side Effects of An Important Antifungal Drug

A change to the structure of antifungal medication amphotericin B alters the way it interacts with cell membranes, researchers say, allowing it to destroy fungal cells while sparing mammalian ones. By conjugating the drug to cholic acid, researchers were able to prevent the drug’s aggregate form from penetrating mammalian cell membranes, while still allowing the monomeric form to affect fungal cells. This breakthrough may lead to improvements in other medications that can rupture human cell membranes, such as antibiotics.

Design Improvement Increases the Utility of Sodium-Ion Batteries

Researchers say they’ve come up with a solid-state sodium-ion battery design that doesn’t overheat due to short-circuiting. By increasing contact between the solid sodium anode and solid electrolyte, researchers say the design prevents the formation of problematic dendrites that lead to short circuits. The new design is efficient and has a good cycle life, making it potentially useful for storing renewable energy.

Time-Release Fertilizer Could Improve Crop Yields, Reduce Runoff

By releasing its nutrients over time, a new fertilizer could improve crop yields while reducing the amount of ammonia-laced runoff water. Researchers combined urea, a common source of nitrogen in fertilizer, with nanoparticles of a form of calcium phosphate to create a time-released fertilizer. The new fertilizer is more expensive, but the cost is balanced by the fact that farmers won’t need to use as much of it.



Protein-Based Drugs Get Stability Boost From New Polymer

A newly-developed polymer could help extend the lifetime of proteins like insulin, both in and out of the body. Trehalose-based glycopolymer increased the in vivo lifetime of insulin in mice during recent trials, while also protecting the insulin from aggregating under heat and mechanical stress. The polymer could help stabilize drugs in parts of the world where continuous refrigeration is less common.


That’s just a small sample of the robust coverage C&EN provides. Get the latest news in your discipline with weekly e-mail updates.

Check Out Sukbok Chang’s Lab in 360°

Sukbok Chang is a Professor at KAIST (Korea Advanced Institute of Science & Technology) and Associate Editor of ACS Catalysis. We visited Professor Chang for a tour of his lab and caputred the experience in an immersive 360° video.

IMPORTANT NOTE TO ACS AXIAL READERS! This is a 360º video, which means you can use your cursor or smartphone to navigate around inside the lab—and look at whatever you want—just as if you were there in person. This functionality is supported in Chrome, Firefox, Internet Explorer, and Opera browsers. If you’re viewing this on a mobile device, try watching the video through the YouTube app to get the full effect.

With this functionality in mind, please check out this In the Lab 360° video:

Learn more about Professor Subok Chang and ACS Catalysis.



Communicating the Impact of Climate Change on Reddit

On February 14, ACS hosted a Reddit AMA with ACS Expert Andy Jorgensen on communicating climate change information with non-scientists. Jorgensen is an Associate Professor of Chemistry and Environmental Sciences at the University of Toledo, where works with his students to understand how people learn scientific principles. His most recent work includes developing educational materials on climate change, putting the science in a context that is easy for anyone to understand.

Given the hot-button topic that is climate change, Redditors were clamoring to ask Professor Jorgensen about his thoughts on the matter. Check out some of the questions and answers below:

/u/parkerLS: How do you respond to climate change deniers who will argue that you are biased because your career path is directly tied to claiming that climate change is a reality?

Professor Jorgensen: I give several answers to this very common comment. Scientists are generally honest, but if there are problems or flaws, other scientists provide corrections or context. This is a field where good or bad news, supported by facts, can be convincing. Some reply that there is more money in other fields, like drilling for oil, but that might not be convincing. I use the analogous situation – why do you believe that the antibiotic given for your infection will likely work even though there is much more money for scientists in that field for being influenced by financial matters. We are constantly checked by other professionals. We are not part of a giant conspiracy.

/u/Silverback_6: Have you ever been asked a question that left you stumped? Follow-up – what’s the most frequently asked “gotcha” question that ends up falling flat after you can show some contradictory evidence?

Professor Jorgensen: Good question. Early in my time in giving presentations I could not definitely answer the question of why the earth was warmer eons ago. I subsequently studied the issued and learned that the position of the earth with respect to the sun – our orbit – has changed over time, which caused a different amount of the sun’s energy to hit the earth. That is not the situation at present. The sun’s radiance to us has changed little in decades.

/u/SetPhazersToStun: What is the most compelling evidence to suggest we’ve broken away from the predictable climate cycles we’ve observed for the last 100,000 years or more?

Professor Jorgensen: There are many indications: temperature changes in just the last few decades, including successive records for the world average temperature in 2014, 2015 and 2016. Three years in a row is compelling. Others include loss of Arctic ice, which reflects warmer oceans. Increasing acidity of oceans due to absorption of carbon dioxide. Increased sea levels, due to both thermal expansion of water and melting land ice. Also, compelling evidence comes from biology – early budding of plants, shifts in zones were plants and animals are migrating to.

/u/mistymountainz: Hi. What has been the fact you have used in your teachings that usually works to convince those who don’t believe that climate change is real?

Professor Jorgensen: Both in my regular teaching and in speaking about climate change I use personal response devices, called “clickers” to gauge the response of members of the audience. In speaking with many groups on climate I have found that a single hour of showing document facts – temperature records from NASA, gas emissions from the D of Energy – and one fifth of the group has become convinced of the reality of climate change.

Learn more about ACS Science Tuesdays on Reddit here.

ACS Editors’ Choice: Engineering Defects to Create Superior Nanomaterials — and more!

This week: Engineering defects to create superior nanomaterials,  interactions of emulsion drops and gas bubbles in complex fluids, targeted photothermal breast cancer therap — and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!
Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein

J. Phys. Chem. B, Article ASAP
DOI: 10.1021/acs.jpcb.6b11976
Visualization of mycobacterial membrane dynamics in live cells

J. Am. Chem. Soc., Article ASAP
DOI: 10.1021/jacs.6b12541
Defect Engineering: A Path toward Exceeding Perfection

ACS Omega, 2017, 2 (2), pp 663–669
DOI: 10.1021/acsomega.6b00500

Surface Forces and Interaction Mechanisms of Emulsion Drops and Gas Bubbles in Complex Fluids

Langmuir, Article ASAP
DOI: 10.1021/acs.langmuir.6b04669
Bioconjugation of Gold Nanobipyramids for SERS Detection and Targeted Photothermal Therapy in Breast Cancer

ACS Biomater. Sci. Eng., Article ASAP
DOI: 10.1021/acsbiomaterials.7b00021
Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites

ACS Med. Chem. Lett., Article ASAP
DOI: 10.1021/acsmedchemlett.7b00011
DNA Adduct Profiles Predict in Vitro Cell Viability after Treatment with the Experimental Anticancer Prodrug PR104A

Chem. Res. Toxicol., Article ASAP
DOI: 10.1021/acs.chemrestox.6b00412
Love ACS Editors’ Choice? Get a weekly e-mail of the latest ACS Editor’s Choice articles and never miss a breakthrough!

JACS Image Challenge: Spectacularly Scientifically Fun!

In order to allow readers to interact with research content in an educational manner, the Journal of the American Chemical Society is launching the JACS Image Challenge on our Facebook page!

JACS Image Challenge is a recurring multiple-choice question about a recent JACS article or communication. You may take a look at the image from a recent JACS publication and then respond to the related question to test your understanding of chemistry. The goal is for this challenge to provide an interactive, enjoyable experience for all users, but be particularly valuable to advancing understanding of students.

All authors of recent JACS publications are welcome to submit their own Image Challenge questions. Please adhere to the multiple-choice format of the current question, and send your question to managing.editor@jacs.acs.org. Do not forget to include the correct answer with a short explanation and your suggested figure from the publication. Questions may be edited for style and accuracy, and we may not be able to post every image challenges we receive.

Come and take the first JACS Image Challenge in 2017:

Take the ACS Infectious Diseases #ACSmicrobiome Quiz

The microbiome is a hot topic in the popular media and in labs around the world. Chemists, biochemists, and other scientists are continually making new discoveries about the microbiome and how it affects health and the environment.

To highlight the latest chemistry, biochemistry, and chemical biology research on how the microbiome relates to infectious diseases, ACS Infectious Diseases is publishing a Special Issue titled The Microbiome with Guest Editor Emily Balskus later this year. If you’re doing research in these areas, please visit The Microbiome Special Issue call for papers to learn more and submit your manuscript.

Take The Microbiome Quiz!

Take the Microbiome Quiz
1. Which area on the surface of the human body has been found to host the most diverse collection of microbes?
Behind the ear

On the forearm

In the bellybutton

In-between the toes

It’s no secret that the human body is made up largely of microbes – over 100 trillion by some estimates. By what ratio do microbes outnumber human cells in our bodies?
10 to 1

100 to 1

1,000 to 1

10,000 to 1

The human digestive tract is home to a majority of the microbes that make up the human microbiome. Roughly what percent of an individual’s microbiome can be found in their digestive tract?





A recent Dutch study concluded that individuals who engage in intimate kissing have a more similar oral microbiota composition compared with unrelated individuals. On average, how many bacteria did they find were transferred in a 10 second intimate kiss?
10 million

80 million

120 million

200 million

Which winner of the Nobel Prize in Medicine purposely ingested Heliobacter pylori in order to prove that stomach ulcers are caused by bacteria, not stress?
Linda Buck

Harold zur Hausen

Barry Marshall

Shinya Yamanaka

Which ACS journal is currently accepting papers for an upcoming Special Issue on the Microbiome?
ACS Infectious Diseases

Journal of Proteome Research

ACS Medicinal Chemistry


Think You Know the Human Microbiome?
ACS Infectious Diseases invites you to take this short, six question quiz to test your knowledge of some of the more interesting developments in research surrounding the human microbiome over the past 15 years. Go with your gut and see if you can get all six questions right! Take our quiz and find out!

Whether you’re researching the microbiome or not, it’s hard at work having an effect on your body and your health. Take this short ACS Infectious Diseases quiz and test your knowledge on the human microbiome then watch The Microbiome in Health and Disease, a webinar sponsored by ACS Infectious Diseases and Journal of Proteome Research to learn more.

4 Keys to Increasing Submission Success for Japanese Researchers

Japan’s greatest scientific research strengths may be in physics, but the country also has influence in the disciplines of pharmacology and toxicology, biology, and biochemistry. Researchers in Japan are making great progress in the areas of development of synthetic methodology with catalysis, organic materials including supramolecular chemistry, photo- and electrofunctional materials, soft matter, nanoparticles, and formulations for pharmaceuticals. What’s more, over the past 5–8 years, there has been a surge in biotechnology research in Japan. With a rapid increase in publications across many emerging areas of chemistry, it’s more important than ever for researchers in Japan to produce high-quality, original work that sets them apart. Yet Japanese chemists also face particular challenges that they must overcome if they way to see their work appear in top-tier chemistry research journals.

To help chemists in Japan, we’ve identified 4 areas that can make or break a Japanese researchers’ submission to a high-quality, peer reviewed journal. In our special white paper, “Growing Globally: How Scientists in Japan Can Share Their Research with the World,” readers will learn about manuscript errors that can hold them back, as well as research considerations, approaches to partnership opportunities and other factors that can help Japanese researchers put their best foot forward when submitting their work. Included are special suggestions for publishing papers via open access channels, a move that can help promising new research find the wide audience it deserves. The paper also includes a section with tips for students and other young chemists from Japan, to help them get their careers off to a great start. Throughout, the white paper points readers to resources from across the ACS that Japanese Chemists can use to improve their work, present it in the best light, and find submission success in the world’s best chemistry journals.

Download Your Copy of “Growing Globally: How Scientists in Japan Can Share Their Research with the World” Today!

Get to Know The Journal of Organic Chemistry Editor-in-Chief Scott J. Miller

The Journal of Organic Chemistry’s new Editor-in-Chief, Scott J. Miller, brings considerable experience to the role he assumed on January 1. He is the Irénée du Pont Professor of Chemistry at Yale University, where he served as chair of the Department of Chemistry from 2009 through 2016. Miller has published important papers, including his work on minimal peptidic catalysts for important enantioselective and site-selective reactions. Among other honors, Miller is the recipient of the 2011 National Institutes of Health MERIT Award and the 2003 Pfizer Award for Creativity in Organic Chemistry, and ACS honored him with both the 2004 Arthur C. Cope Scholar Award and the 2016 Award for Creative Work in Synthetic Organic Chemistry.

But Miller wasn’t only chosen to lead The Journal of Organic Chemistry because of his professional accolades and important research. He also brings a new focus and vision to the journal, as outlined in this January 6 editorial.

“My hope for J. Org. Chem. is to see it flourish as it has historically and in some new ways in the future. The beauty and mystery of organic chemistry is the basis for my optimism,” he writes. “The reach of organic chemistry is phenomenal. Yet, as I tell my students, to me it still feels like a field not so far from its origin. In ten years, today’s research will look quite primitive. In another ten years, yet again. J. Org. Chem. has a vital role to play in stimulating and chronicling the journey.”

Writing the Next Chapter in Organic Chemistry Research

At first, Miller wasn’t sure he wanted to take over as Editor-in-Chief of The Journal of Organic Chemistry, as he explains in this video interview. Find out what changed his mind and how he plans to strike a balance between maintaining the journal’s traditional strengths and adapting along with the field:

Meet The Journal of Organic Chemistry’s New Associate Editors

To help him lead this new chapter in The Journal of Organic Chemistry’s history, Miller added four new Associate Editors to its editorial team:

Each of these new Associate Editors brings unique expertise and perspective and contributes to making the journal a truly global endeavor. In this video Miller describes each of them and explains why he invited him to join the journal’s editorial team:

These newest members of The Journal of Organic Chemistry’s editorial team join a talented and diverse group of continuing Associate Editors:

Want to receive more news about The Journal of Organic Chemistry and its editorial team? Sign up to receive email updates from the journal and ACS Publications.

ACS Central Science Earns Prestigious PROSE Award

When ACS Publications launched ACS Central Science in 2015, it aimed to chart a new course in how innovative research is shared not just with the scientific community, but with the public at large. That approach recently earned the journal the prestigious PROSE Journal/Award for Innovation.

Presented by the Association of American Publishers, the PROSE awards recognize excellence in professional and scholarly publishing. The PROSE Innovation Award, is particularly noteworthy because it is not issued annually, but rather at the judges’ discretion to acknowledge particularly unique achievements among new journals,.

Led by Editor-in-Chief Carolyn R. Bertozzi of Stanford University, ACS Central Science is designed to appeal to a broad audience across the chemical, physical, life, and multidisciplinary sciences. At its core is the mission to elevate chemistry as the central science.

“This is wonderful news and a perfect reflection of the hard word and creativity that the ACS team has brought to this fulfilling and important endeavor. Thank you all for your contributions that made this possible,” said Bertozzi.

In its first 22 issues, ACS Central Science published more than 150 research articles and more than 100 editorials, news stories, interviews, and commentaries. It has attracted and accepted submissions from leading scientific authors, including four Nobel laureates.

While the journal is highly selective in terms of the submissions it publishes, it has made tremendous strides in sharing that research with broader audiences. ACS Central Science is ACS Publications’ first fully open access journal and the first to receive a dedicated mobile app. It is supported by smart multimedia pieces developed for general audiences, LiveSlides, a dynamic website, and an active social media presence.

In addition, the journal staff worked with the ACS Office of External Affairs & Communication to develop an embargoed press release process to promote the research it publishes. The journal has been featured in hundreds pieces of online press coverage with a combined total audience exceeding 1 billion.

The PROSE award is recognition that the journal is building a global audience for groundbreaking science—and is setting the bar for accessibility to thought-provoking research and commentary.