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Discover the Most-Read Multidisciplinary Journal Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read multidisciplinary articles that appeared in each related ACS Publications journal in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
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Accounts of Chemical Research

Analyte-Responsive Hydrogels: Intelligent Materials for Biosensing and Drug Delivery
Acc. Chem. Res., 2017, 50 (2), pp 170–178
DOI: 10.1021/acs.accounts.6b00533

Entropy and Enzyme Catalysis
Open access through ACS AuthorChoice
Acc. Chem. Res., 2017, 50 (2), pp 199–207
DOI: 10.1021/acs.accounts.6b00321

From Carbon-Based Nanotubes to Nanocages for Advanced Energy Conversion and Storage
Acc. Chem. Res., 2017, 50 (2), pp 435–444
DOI: 10.1021/acs.accounts.6b00541

Self-Templated Formation of Hollow Structures for Electrochemical Energy Applications
Acc. Chem. Res., 2017, 50 (2), pp 293–301
DOI: 10.1021/acs.accounts.6b00480

Molecular Aggregate Photophysics beyond the Kasha Model: Novel Design Principles for Organic Materials
Acc. Chem. Res., 2017, 50 (2), pp 341–350
DOI: 10.1021/acs.accounts.6b00576

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ACS Central Science

Two-Way Chemical Communication between Artificial and Natural Cells
Open access through ACS AuthorChoice
ACS Cent. Sci., 2017, 3 (2), pp 117–123
DOI: 10.1021/acscentsci.6b00330

Living Additive Manufacturing: Transformation of Parent Gels into Diversely Functionalized Daughter Gels Made Possible by Visible Light Photoredox Catalysis
Open access through ACS AuthorChoice
ACS Cent. Sci., 2017, 3 (2), pp 124–134
DOI: 10.1021/acscentsci.6b00335

Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry
Open access through ACS AuthorChoice
ACS Cent. Sci., 2017, 3 (2), pp 101–109
DOI: 10.1021/acscentsci.6b00297

Core–Shell Nanoparticle Coating as an Interfacial Layer for Dendrite-Free Lithium Metal Anodes
Open access through ACS AuthorChoice
ACS Cent. Sci., 2017, 3 (2), pp 135–140
DOI: 10.1021/acscentsci.6b00389

Surprising Degradation Products from an Under-Fire Insecticide
What if the environmental risks of neonicotinoids like imidacloprid are only the beginning of the story (Environmental Science & Technology)?
Open access through ACS AuthorChoice
ACS Cent. Sci., 2017, 3 (2), pp 97–98
DOI: 10.1021/acscentsci.7b00033

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ACS Omega

Solid-Phase Synthesis of Self-Assembling Multivalent π-Conjugated Peptides
Open access through ACS AuthorChoice
ACS Omega, 2017, 2 (2), pp 409–419
DOI: 10.1021/acsomega.6b00414

Evaluation of Silk Inverse Opals for “Smart” Tissue Culture
Open access through ACS AuthorChoice
ACS Omega, 2017, 2 (2), pp 470–477
DOI: 10.1021/acsomega.6b00320

Temperature-Dependent Reinforcement of Hydrophilic Rubber Using Ice Crystals
Open access through ACS AuthorChoice
ACS Omega, 2017, 2 (2), pp 363–371
DOI: 10.1021/acsomega.6b00443

Dual-Functional-Tag-Facilitated Protein Labeling and Immobilization
Open access through ACS AuthorChoice
ACS Omega, 2017, 2 (2), pp 522–528
DOI: 10.1021/acsomega.6b00512

Comparison of the Optical and Electrochemical Properties of Bi(perylene diimide)s Linked through Ortho and Bay Positions
Open access through ACS AuthorChoice
ACS Omega, 2017, 2 (2), pp 377–385
DOI: 10.1021/acsomega.6b00537

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Chemical Reviews

Nanomaterials for In Vivo Imaging
Chem. Rev., 2017, 117 (3), pp 901–986
DOI: 10.1021/acs.chemrev.6b00073

Surface-Initiated Controlled Radical Polymerization: State-of-the-Art, Opportunities, and Challenges in Surface and Interface Engineering with Polymer Brushes
Open access through ACS AuthorChoice
Chem. Rev., 2017, 117 (3), pp 1105–1318
DOI: 10.1021/acs.chemrev.6b00314

Porous Organic Materials: Strategic Design and Structure–Function Correlation
Chem. Rev., 2017, 117 (3), pp 1515–1563
DOI: 10.1021/acs.chemrev.6b00439

New Insights into Perfluorinated Sulfonic-Acid Ionomers
Open access through ACS AuthorChoice
Chem. Rev., 2017, 117 (3), pp 987–1104
DOI: 10.1021/acs.chemrev.6b00159

Functional Graphene Nanomaterials Based Architectures: Biointeractions, Fabrications, and Emerging Biological Applications
Chem. Rev., 2017, 117 (3), pp 1826–1914
DOI: 10.1021/acs.chemrev.6b00520

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Journal of the American Chemical Society

Fe-Catalyzed C–C Bond Construction from Olefins via Radicals
Open access through ACS AuthorChoice
J. Am. Chem. Soc., 2017, 139 (6), pp 2484–2503
DOI: 10.1021/jacs.6b13155

Benzyltriboronates: Building Blocks for Diastereoselective Carbon–Carbon Bond Formation
J. Am. Chem. Soc., 2017, 139 (7), pp 2589–2592
DOI: 10.1021/jacs.6b12896

C(sp2)–H Borylation of Fluorinated Arenes Using an Air-Stable Cobalt Precatalyst: Electronically Enhanced Site Selectivity Enables Synthetic Opportunities
J. Am. Chem. Soc., 2017, 139 (7), pp 2825–2832
DOI: 10.1021/jacs.6b13346

Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds
Open access through ACS AuthorChoice
J. Am. Chem. Soc., 2017, 139 (7), pp 2577–2580
DOI: 10.1021/jacs.6b12840

Highly Regio- and Enantioselective Vicinal Dihalogenation of Allyl Amides
J. Am. Chem. Soc., 2017, 139 (6), pp 2132–2135
DOI: 10.1021/jacs.6b09203

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Journal of Chemical Education

The Slippery Slope of Student Evaluations
J. Chem. Educ., 2017, 94 (2), pp 131–132
DOI: 10.1021/acs.jchemed.7b00046

Mapping the Teaching of History of Chemistry in Europe
J. Chem. Educ., 2017, 94 (2), pp 133–136
DOI: 10.1021/acs.jchemed.6b00401

Capturing Chemical Identity Thinking
Open access through ACS AuthorChoice
J. Chem. Educ., 2017, 94 (2), pp 137–148
DOI: 10.1021/acs.jchemed.6b00387

Stereogame: An Interactive Computer Game That Engages Students in Reviewing Stereochemistry Concepts
J. Chem. Educ., 2017, 94 (2), pp 248–250
DOI: 10.1021/acs.jchemed.6b00475

Colorful and Creative Chemistry: Making Simple Sustainable Paints with Natural Pigments and Binders
J. Chem. Educ., 2017, 94 (2), pp 211–215
DOI: 10.1021/acs.jchemed.6b00591

Discover the Most-Read Physical Chemistry Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read physical chemistry articles that appeared in each related ACS Publications journal in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
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ACS Energy Letters

Electrochemical Capture and Release of Carbon Dioxide
Open access through ACS Editors’ Choice
ACS Energy Lett., 2017, 2 (2), pp 454–461
DOI: 10.1021/acsenergylett.6b00608

Advances and Obstacles on Perovskite Solar Cell Research from Material Properties to Photovoltaic Function
ACS Energy Lett., 2017, 2 (2), pp 520–523
DOI: 10.1021/acsenergylett.7b00085

Are You Making the Right Presentation at the Scientific Meeting?
ACS Energy Lett., 2017, 2 (2), pp 408–409
DOI: 10.1021/acsenergylett.7b00004

Next-Generation Solar Cells and Conversion of Solar Energy
ACS Energy Lett., 2017, 2 (2), pp 334–335
DOI: 10.1021/acsenergylett.6b00645

High-Efficiency Rubidium-Incorporated Perovskite Solar Cells by Gas Quenching
Open access through ACS AuthorChoice
ACS Energy Lett., 2017, 2 (2), pp 438–444
DOI: 10.1021/acsenergylett.6b00697

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ACS Photonics

Visible Light, Wide-Angle Graded Metasurface for Back Reflection
ACS Photonics, 2017, 4 (2), pp 228–235
DOI: 10.1021/acsphotonics.6b00965

Optimization of Nanoparticle-Based SERS Substrates through Large-Scale Realistic Simulations
Open access through ACS Editors’ Choice
ACS Photonics, 2017, 4 (2), pp 329–337
DOI: 10.1021/acsphotonics.6b00786

Light Outcoupling from Quantum Dot-Based Microdisk Laser via Plasmonic Nanoantenna
ACS Photonics, 2017, 4 (2), pp 275–281
DOI: 10.1021/acsphotonics.6b00552

All-Optical Pattern Recognition and Image Processing on a Metamaterial Beam Splitter
Open access through ACS AuthorChoice
ACS Photonics, 2017, 4 (2), pp 217–222
DOI: 10.1021/acsphotonics.6b00921

Tunable Full-Color Electroluminescence from All-Organic Optical Upconversion Devices by Near-Infrared Sensing
ACS Photonics, 2017, 4 (2), pp 223–227
DOI: 10.1021/acsphotonics.6b00964

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Energy & Fuels

Simulation of Asphaltene Aggregation through Molecular Dynamics: Insights and Limitations
Open access through ACS AuthorChoice
Energy Fuels, 2017, 31 (2), pp 1108–1125
DOI: 10.1021/acs.energyfuels.6b02161

Chemical Kinetic Insights into the Octane Number and Octane Sensitivity of Gasoline Surrogate Mixtures
Energy Fuels, 2017, 31 (2), pp 1945–1960
DOI: 10.1021/acs.energyfuels.6b02659

Segregation of Amphiphilic Polymer-Coated Nanoparticles to Bicontinuous Oil/Water Microemulsion Phases
Energy Fuels, 2017, 31 (2), pp 1339–1346
DOI: 10.1021/acs.energyfuels.6b02687

Techno-economic Analysis of Metal–Organic Frameworks for Hydrogen and Natural Gas Storage
Energy Fuels, 2017, 31 (2), pp 2024–2032
DOI: 10.1021/acs.energyfuels.6b02510

New Composite Viscosity Reducer with Both Asphaltene Dispersion and Emulsifying Capability for Heavy and Ultraheavy Crude Oils
Energy Fuels, 2017, 31 (2), pp 1159–1173
DOI: 10.1021/acs.energyfuels.6b02265

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Industrial & Engineering Chemistry Research 

Biomimetic Superhydrophobic Engineering Metal Surface with Hierarchical Structure and Tunable Adhesion: Design of Microscale Pattern
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (4), pp 907–919
DOI: 10.1021/acs.iecr.6b03936

An Effective Biocatalytic Reactor–Rotating Packed Bed Applied in Hydrolysis Reactions
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (5), pp 1349–1353
DOI: 10.1021/acs.iecr.6b03381

Comprehensive Analysis of Sorption Enhanced Steam Methane Reforming in a Variable Volume Membrane Reactor
Ind. Eng. Chem. Res., 2017, 56 (7), pp 1758–1771
DOI: 10.1021/acs.iecr.6b04392

Zeolitic Imidazolate Framework-8 (ZIF-8) Membranes for Kr/Xe Separation
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1682–1686
DOI: 10.1021/acs.iecr.6b04868

Facile Synthesis and Direct Activation of Zirconium Based Metal–Organic Frameworks from Acetone
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1478–1484
DOI: 10.1021/acs.iecr.6b04361

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Journal of Chemical & Engineering Data

The Viscosity and Density of Ionic Liquid + Tetraglyme Mixtures and the Effect of Tetraglyme on CO2 Solubility
J. Chem. Eng. Data, 2017, 62 (2), pp 608–622
DOI: 10.1021/acs.jced.6b00596

Evaluating Characteristic Parameters for Carbon Dioxide in the Sanchez–Lacombe Equation of State
J. Chem. Eng. Data, 2017, 62 (2), pp 585–595
DOI: 10.1021/acs.jced.6b00743

Correction to “Measurement and Correlation of 1,4-Naphthoquinone and of Plumbagin Solubilities in Supercritical Carbon Dioxide”
J. Chem. Eng. Data, 2017, 62 (2), pp 886–887
DOI: 10.1021/acs.jced.7b00025

Thermodynamic Study of Methylene Blue Adsorption on Carbon Nanotubes Using Isothermal Titration Calorimetry: A Simple and Rigorous Approach
J. Chem. Eng. Data, 2017, 62 (2), pp 729–737
DOI: 10.1021/acs.jced.6b00804

Correction to “Liquid–Liquid Equilibria in Aqueous Mixtures of Alkylmethylimidazolium Glutamate with Potassium Carbonate and Some Physicochemical Properties of Aqueous [Cnmim][Glu] (n = 4, 6, 8) Solutions”
J. Chem. Eng. Data, 2017, 62 (2), pp 885–885
DOI: 10.1021/acs.jced.6b00906

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Journal of Chemical Information and Modeling

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine
Open access through ACS AuthorChoice
J. Chem. Inf. Model., 2017, 57 (2), pp 115–121
DOI: 10.1021/acs.jcim.6b00686

Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide
J. Chem. Inf. Model., 2017, 57 (2), pp 190–202
DOI: 10.1021/acs.jcim.6b00443

Binding Pose Flip Explained via Enthalpic and Entropic Contributions
Open access through ACS AuthorChoice
J. Chem. Inf. Model., 2017, 57 (2), pp 345–354
DOI: 10.1021/acs.jcim.6b00483

Creating the New from the Old: Combinatorial Libraries Generation with Machine-Learning-Based Compound Structure Optimization
J. Chem. Inf. Model., 2017, 57 (2), pp 133–147
DOI: 10.1021/acs.jcim.6b00426

pmx Webserver: A User Friendly Interface for Alchemistry
J. Chem. Inf. Model., 2017, 57 (2), pp 109–114
DOI: 10.1021/acs.jcim.6b00498

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Journal of Chemical Theory and Computation

Multireference Perturbation Theory with Cholesky Decomposition for the Density Matrix Renormalization Group
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 451–459
DOI: 10.1021/acs.jctc.6b00778

Quantitative Assessment of Molecular Dynamics Sampling for Flexible Systems
J. Chem. Theory Comput., 2017, 13 (2), pp 400–414
DOI: 10.1021/acs.jctc.6b00823

Systematic Quantum Mechanical Region Determination in QM/MM Simulation
J. Chem. Theory Comput., 2017, 13 (2), pp 563–576
DOI: 10.1021/acs.jctc.6b01049

Modeling Diversity in Structures of Bacterial Outer Membrane Lipids
J. Chem. Theory Comput., 2017, 13 (2), pp 811–824
DOI: 10.1021/acs.jctc.6b00856

A Monte Carlo Resampling Approach for the Calculation of Hybrid Classical and Quantum Free Energies
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 415–424
DOI: 10.1021/acs.jctc.6b00506

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The Journal of Physical Chemistry A

Natural Bond Orbitals and the Nature of the Hydrogen Bond
J. Phys. Chem. A, 2017, 121 (7), pp 1531–1534
DOI: 10.1021/acs.jpca.6b12930

Cluster Model Studies of Anion and Molecular Specificities via Electrospray Ionization Photoelectron Spectroscopy
Open access through ACS Editors’ Choice
J. Phys. Chem. A, 2017, 121 (7), pp 1389–1401
DOI: 10.1021/acs.jpca.6b09784

Why Are Addition Reactions to N2 Thermodynamically Unfavorable?
J. Phys. Chem. A, 2017, 121 (5), pp 1140–1144
DOI: 10.1021/acs.jpca.6b11728

Formation Mechanisms of Naphthalene and Indene: From the Interstellar Medium to Combustion Flames
J. Phys. Chem. A, 2017, 121 (5), pp 901–926
DOI: 10.1021/acs.jpca.6b09735

“Watching” the Dark State in Ultrafast Nonadiabatic Photoisomerization Process of a Light-Driven Molecular Rotary Motor
J. Phys. Chem. A, 2017, 121 (6), pp 1240–1249
DOI: 10.1021/acs.jpca.6b12253

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The Journal of Physical Chemistry B

Editorial – Virtual Issue of JPCB on Biophysics
J. Phys. Chem. B, 2017, 121 (5), pp 913–914
DOI: 10.1021/acs.jpcb.6b12749

Characterization of Nanocellulose Using Small-Angle Neutron, X-ray, and Dynamic Light Scattering Techniques
J. Phys. Chem. B, 2017, 121 (6), pp 1340–1351
DOI: 10.1021/acs.jpcb.6b11425

A Spectroscopic and Molecular Simulation Approach toward the Binding Affinity between Lysozyme and Phenazinium Dyes: An Effect on Protein Conformation
J. Phys. Chem. B, 2017, 121 (7), pp 1475–1484
DOI: 10.1021/acs.jpcb.6b10991

The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space
J. Phys. Chem. B, 2017, 121 (7), pp 1576–1586
DOI: 10.1021/acs.jpcb.7b00253

Coarse-Grained Molecular Simulation of the Hierarchical Self-Assembly of π-Conjugated Optoelectronic Peptides
J. Phys. Chem. B, 2017, 121 (7), pp 1684–1706
DOI: 10.1021/acs.jpcb.6b10165

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The Journal of Physical Chemistry C

Photon Reabsorption in Mixed CsPbCl3:CsPbI3 Perovskite Nanocrystal Films for Light-Emitting Diodes
J. Phys. Chem. C, 2017, 121 (7), pp 3790–3796
DOI: 10.1021/acs.jpcc.6b12828

Light-Induced Degradation of CH3NH3PbI3 Hybrid Perovskite Thin Film
J. Phys. Chem. C, 2017, 121 (7), pp 3904–3910
DOI: 10.1021/acs.jpcc.6b11853

Ag Doping of Organometal Lead Halide Perovskites: Morphology Modification and p-Type Character
J. Phys. Chem. C, 2017, 121 (7), pp 3673–3679
DOI: 10.1021/acs.jpcc.6b09722

Control of Symmetry Breaking Size and Aspect Ratio in Gold Nanorods: Underlying Role of Silver Nitrate
J. Phys. Chem. C, 2017, 121 (6), pp 3549–3559
DOI: 10.1021/acs.jpcc.6b10343

Tunable Structural, Electronic, and Optical Properties of Layered Two-Dimensional C2N and MoS2 van der Waals Heterostructure as Photovoltaic Material
J. Phys. Chem. C, 2017, 121 (6), pp 3654–3660
DOI: 10.1021/acs.jpcc.6b12681

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The Journal of Physical Chemistry Letters

Charge Carrier Trapping at Surface Defects of Perovskite Solar Cell Absorbers: A First-Principles Study
Open access through ACS Editors’ Choice
J. Phys. Chem. Lett., 2017, 8 (4), pp 742–746
DOI: 10.1021/acs.jpclett.7b00055

Cs2InAgCl6: A New Lead-Free Halide Double Perovskite with Direct Band Gap
J. Phys. Chem. Lett., 2017, 8 (4), pp 772–778
DOI: 10.1021/acs.jpclett.6b02682

Spectroscopic Evidences for Strong Hydrogen Bonds with Selenomethionine in Proteins
J. Phys. Chem. Lett., 2017, 8 (4), pp 794–800
DOI: 10.1021/acs.jpclett.6b02931

Electron Transfer from Triplet State of TIPS-Pentacene Generated by Singlet Fission Processes to CH3NH3PbI3 Perovskite
J. Phys. Chem. Lett., 2017, 8 (4), pp 884–888
DOI: 10.1021/acs.jpclett.7b00072

First-Principles Study of Novel Two-Dimensional (C4H9NH3)2PbX4 Perovskites for Solar Cell Absorbers
J. Phys. Chem. Lett., 2017, 8 (4), pp 876–883
DOI: 10.1021/acs.jpclett.7b00003

Discover the Most-Read Organic/Inorganic Chemistry Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read organic and inorganic chemistry articles that appeared in each related ACS Publications journal in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
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ACS Catalysis

A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1025–1029
DOI: 10.1021/acscatal.6b03061

Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1432–1437
DOI: 10.1021/acscatal.6b03388

Breaking Amides using Nickel Catalysis
ACS Catal., 2017, 7 (2), pp 1413–1423
DOI: 10.1021/acscatal.6b03277

Metal–Metal Bonds in Catalysis
ACS Catal., 2017, 7 (2), pp 936–958
DOI: 10.1021/acscatal.6b02692

Catalytic Zirconium/Hafnium-Based Metal–Organic Frameworks
ACS Catal., 2017, 7 (2), pp 997–1014
DOI: 10.1021/acscatal.6b02923

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ACS Combinatorial Science

Synthesis of Novel 5,6-Disubstituted Pyrrolo [2,3-d]Pyrimidine-2,4-Diones Via One-Pot Three-Component Reactions
ACS Comb. Sci., 2017, 19 (2), pp 108–112
DOI: 10.1021/acscombsci.6b00147

Rationally Designed Peptides and Peptidomimetics as Inhibitors of Amyloid-β (Aβ) Aggregation: Potential Therapeutics of Alzheimer’s Disease
ACS Comb. Sci., 2017, 19 (2), pp 55–80
DOI: 10.1021/acscombsci.6b00116

Neural-Network-Biased Genetic Algorithms for Materials Design: Evolutionary Algorithms That Learn
ACS Comb. Sci., 2017, 19 (2), pp 96–107
DOI: 10.1021/acscombsci.6b00136

Combining a Ru(II) “Building Block” and Rapid Screening Approach to Identify DNA Structure-Selective “Light Switch” Compounds
ACS Comb. Sci., 2017, 19 (2), pp 85–95
DOI: 10.1021/acscombsci.6b00119

Fluorophore Metal–Organic Complexes: High-Throughput Optical Screening for Aprotic Electrochemical Systems
ACS Comb. Sci., 2017, 19 (2), pp 81–84
DOI: 10.1021/acscombsci.6b00171

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ACS Medicinal Chemistry Letters

Communicating Our Science to Our Customers: Drug Discovery in Five Simple Experiments.
ACS Med. Chem. Lett., 2017, 8 (2), pp 143–144
DOI: 10.1021/acsmedchemlett.7b00015

Intramolecular Hydrogen Bond Expectations in Medicinal Chemistry
ACS Med. Chem. Lett., 2017, 8 (2), pp 139–142
DOI: 10.1021/acsmedchemlett.7b00002

Design and Synthesis of Novel, Selective GPR40 AgoPAMs
ACS Med. Chem. Lett., 2017, 8 (2), pp 221–226
DOI: 10.1021/acsmedchemlett.6b00443

Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2
ACS Med. Chem. Lett., 2017, 8 (2), pp 256–260
DOI: 10.1021/acsmedchemlett.6b00486

Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
ACS Med. Chem. Lett., 2017, 8 (2), pp 239–244
DOI: 10.1021/acsmedchemlett.6b00464

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Bioconjugate Chemistry

Quantitative Conjugated Payload Measurement Using Enzymatic Release of Antibody–Drug Conjugate with Cleavable Linker
Bioconjugate Chem., 2017, 28 (2), pp 620–626
DOI: 10.1021/acs.bioconjchem.6b00695

Peptide-Based Stealth Nanoparticles for Targeted and pH-Triggered Delivery
Bioconjugate Chem., 2017, 28 (2), pp 627–635
DOI: 10.1021/acs.bioconjchem.6b00701

Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates
Bioconjugate Chem., 2017, 28 (2), pp 371–381
DOI: 10.1021/acs.bioconjchem.6b00530

Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes
Bioconjugate Chem., 2017, 28 (2), pp 341–352
DOI: 10.1021/acs.bioconjchem.6b00433

Automated, Resin-Based Method to Enhance the Specific Activity of Fluorine-18 Clicked PET Radiotracers
Bioconjugate Chem., 2017, 28 (2), pp 583–589
DOI: 10.1021/acs.bioconjchem.6b00678

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Inorganic Chemistry

Activating Fe(I) Porphyrins for the Hydrogen Evolution Reaction Using Second-Sphere Proton Transfer Residues
Inorg. Chem., 2017, 56 (4), pp 1783–1793
DOI: 10.1021/acs.inorgchem.6b01707

Bifunctional Imidazolium-Based Ionic Liquid Decorated UiO-67 Type MOF for Selective CO2 Adsorption and Catalytic Property for CO2 Cycloaddition with Epoxides
Inorg. Chem., 2017, 56 (4), pp 2337–2344
DOI: 10.1021/acs.inorgchem.6b03169

Green Synthesis of Zr-CAU-28: Structure and Properties of the First Zr-MOF Based on 2,5-Furandicarboxylic Acid
Inorg. Chem., 2017, 56 (4), pp 2270–2277
DOI: 10.1021/acs.inorgchem.6b02969

Photoluminescent and Slow Magnetic Relaxation Studies on Lanthanide(III)-2,5-pyrazinedicarboxylate Frameworks
Inorg. Chem., 2017, 56 (4), pp 2108–2123
DOI: 10.1021/acs.inorgchem.6b02774

Water-Stable In(III)-Based Metal–Organic Frameworks with Rod-Shaped Secondary Building Units: Single-Crystal to Single-Crystal Transformation and Selective Sorption of C2H2 over CO2 and CH4
Inorg. Chem., 2017, 56 (4), pp 2188–2197
DOI: 10.1021/acs.inorgchem.6b02840

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Journal of Medicinal Chemistry

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
J. Med. Chem., 2017, 60 (4), pp 1247–1261
DOI: 10.1021/acs.jmedchem.6b01751

Recent Advances in Scaffold Hopping
J. Med. Chem., 2017, 60 (4), pp 1238–1246
DOI: 10.1021/acs.jmedchem.6b01437

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
J. Med. Chem., 2017, 60 (3), pp 839–885
DOI: 10.1021/acs.jmedchem.6b00788

Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A
J. Med. Chem., 2017, 60 (3), pp 1000–1017
DOI: 10.1021/acs.jmedchem.6b01329

Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
J. Med. Chem., 2017, 60 (3), pp 1060–1075
DOI: 10.1021/acs.jmedchem.6b01460

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Journal of Natural Products

Diterpenoids and Lignans from Cephalotaxus fortunei
J. Nat. Prod., 2017, 80 (2), pp 356–362
DOI: 10.1021/acs.jnatprod.6b00802

Concise Syntheses of Hyrtioreticulins C and D via a C-4 Pictet–Spengler Reaction: Revised Signs of Specific Rotations
J. Nat. Prod., 2017, 80 (2), pp 241–245
DOI: 10.1021/acs.jnatprod.7b00008

Branimycins B and C, Antibiotics Produced by the Abyssal Actinobacterium Pseudonocardia carboxydivorans M-227
J. Nat. Prod., 2017, 80 (2), pp 569–573
DOI: 10.1021/acs.jnatprod.6b01107

Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges
J. Nat. Prod., 2017, 80 (2), pp 235–240
DOI: 10.1021/acs.jnatprod.6b00838

Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum
J. Nat. Prod., 2017, 80 (2), pp 298–307
DOI: 10.1021/acs.jnatprod.6b00694

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The Journal of Organic Chemistry

Chlorophyll-Catalyzed Visible-Light-Mediated Synthesis of Tetrahydroquinolines from N,N-Dimethylanilines and Maleimides
Open access through ACS Editors’ Choice
J. Org. Chem., 2017, 82 (4), pp 1888–1894
DOI: 10.1021/acs.joc.6b03034

Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides
J. Org. Chem., 2017, 82 (4), pp 2059–2066
DOI: 10.1021/acs.joc.6b02891

Photoredox-Assisted Reductive Cross-Coupling: Mechanistic Insight into Catalytic Aryl–Alkyl Cross-Couplings
J. Org. Chem., 2017, 82 (4), pp 1996–2003
DOI: 10.1021/acs.joc.6b02830

Synthesis of Rings DEF of Solanoeclepin A
J. Org. Chem., 2017, 82 (4), pp 2045–2058
DOI: 10.1021/acs.joc.6b02886

Synthesis of 5H-Dibenzo[c,e]azepine-5,7(6H)-diones from Benzamides via Palladium-Catalyzed Double C–H Bond Activation
J. Org. Chem., 2017, 82 (4), pp 2288–2293
DOI: 10.1021/acs.joc.6b03087

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Molecular Pharmaceutics

Polymer–Drug Nanoparticles Combine Doxorubicin Carrier and Heparin Bioactivity Functionalities for Primary and Metastatic Cancer Treatment
Mol. Pharmaceutics, 2017, 14 (2), pp 513–522
DOI: 10.1021/acs.molpharmaceut.6b00979

Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract
Mol. Pharmaceutics, 2017, 14 (2), pp 345–358
DOI: 10.1021/acs.molpharmaceut.6b00641

Effect of Particle Size on Drug Loading and Release Kinetics of Gefitinib-Loaded PLGA Microspheres
Mol. Pharmaceutics, 2017, 14 (2), pp 459–467
DOI: 10.1021/acs.molpharmaceut.6b00896

Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
Mol. Pharmaceutics, 2017, 14 (2), pp 523–532
DOI: 10.1021/acs.molpharmaceut.6b01010

Self-Assembly PEGylation Retaining Activity (SPRA) Technology via a Host–Guest Interaction Surpassing Conventional PEGylation Methods of Proteins
Mol. Pharmaceutics, 2017, 14 (2), pp 368–376
DOI: 10.1021/acs.molpharmaceut.6b00678

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Organic Letters

Metal-Free C–H Functionalization of Alkanes by Aryldiazoacetates
Org. Lett., 2017, 19 (4), pp 770–773
DOI: 10.1021/acs.orglett.6b03681

Nickel-Catalyzed Stereoselective Alkenylation of C(sp3)–H Bonds with Terminal Alkynes
Org. Lett., 2017, 19 (4), pp 850–853
DOI: 10.1021/acs.orglett.6b03856

Selective C(sp2)–H Halogenation of “Click” 4-Aryl-1,2,3-triazoles
Org. Lett., 2017, 19 (4), pp 962–965
DOI: 10.1021/acs.orglett.7b00275

Enantioselective Synthesis of Cephalimysins B and C
Org. Lett., 2017, 19 (4), pp 750–753
DOI: 10.1021/acs.orglett.6b03373

Isolation and Total Synthesis of Hoshinolactam, an Antitrypanosomal Lactam from a Marine Cyanobacterium
Org. Lett., 2017, 19 (4), pp 890–893
DOI: 10.1021/acs.orglett.7b00047

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Organic Process Research & Development

Some Items of Interest to Process R&D Chemists and Engineers
Org. Process Res. Dev., 2017, 21 (2), pp 142–152
DOI: 10.1021/acs.oprd.7b00027

In Praise of Short Papers for OPR&D
Org. Process Res. Dev., 2017, 21 (2), pp 141–141
DOI: 10.1021/acs.oprd.7b00012

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Org. Process Res. Dev., 2017, 21 (2), pp 153–164
DOI: 10.1021/acs.oprd.7b00014

Process Development of a CRF1 Receptor Antagonist Based on the Selective Chlorination of a Benzimidazolone via Chlorine Migration
Org. Process Res. Dev., 2017, 21 (2), pp 222–230
DOI: 10.1021/acs.oprd.6b00389

Sustainable and Scalable Fe/ppm Pd Nanoparticle Nitro Group Reductions in Water at Room Temperature
Org. Process Res. Dev., 2017, 21 (2), pp 247–252
DOI: 10.1021/acs.oprd.6b00410

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Organometallics

Coordination Chemistry and Reactivity of Bis(aldimino)pyridine Nickel Complexes in Four Different Oxidation States
Organometallics, 2017, 36 (3), pp 582–593
DOI: 10.1021/acs.organomet.6b00793

Alkene Isomerization by “Sandwich” Diimine-Palladium Catalysts
Organometallics, 2017, 36 (4), pp 787–790
DOI: 10.1021/acs.organomet.6b00856

Flipping the Oxidation State Formalism: Charge Distribution in Organometallic Complexes As Reported by Carbon Monoxide
Organometallics, 2017, 36 (3), pp 622–631
DOI: 10.1021/acs.organomet.6b00820

Rhenium(I) Triscarbonyl Complexes with Redox-Active Amino- and Iminopyridine Ligands: Metal–Ligand Cooperation as Trigger for the Reversible Binding of CO2 via a Dearmomatization/Rearomatization Reaction Sequence
Organometallics, 2017, 36 (4), pp 839–848
DOI: 10.1021/acs.organomet.6b00897

Hidden Enantioselective Hydrogenation of N-Silyl Enamines and Silyl Enol Ethers in Net C═N and C═O Hydrosilylations Catalyzed by Ru–S Complexes with One Monodentate Chiral Phosphine Ligand
Organometallics, 2017, 36 (4), pp 935–943
DOI: 10.1021/acs.organomet.7b00030

Discover the Most-Read Materials Science & Engineering Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read materials science and engineering articles that appeared in relevant ACS Publications journals in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
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ACS Applied Materials & Interfaces

Ruthenium(II) Complex Incorporated UiO-67 Metal–Organic Framework Nanoparticles for Enhanced Two-Photon Fluorescence Imaging and Photodynamic Cancer Therapy
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5699–5708
DOI: 10.1021/acsami.6b12469

Janus Membranes with Opposing Surface Wettability Enabling Oil-to-Water and Water-to-Oil Emulsification
ACS Appl. Mater. Interfaces, 2017, 9 (6), pp 5062–5066
DOI: 10.1021/acsami.7b00017

Preparation of NiCoP Hollow Quasi-Polyhedra and Their Electrocatalytic Properties for Hydrogen Evolution in Alkaline Solution
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5982–5991
DOI: 10.1021/acsami.6b14127

Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug
ACS Appl. Mater. Interfaces, 2017, 9 (6), pp 5067–5076
DOI: 10.1021/acsami.6b12114

Continuous Flow Processing of ZIF-8 Membranes on Polymeric Porous Hollow Fiber Supports for CO2 Capture
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5678–5682
DOI: 10.1021/acsami.6b16297

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ACS Biomaterials Science & Engineering

Editorial: Special Issue on Biomaterials for Immunoengineering
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 106–107
DOI: 10.1021/acsbiomaterials.7b00049

Polymers for DNA Vaccine Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 108–125
DOI: 10.1021/acsbiomaterials.6b00418

In Vivo Expansion of Melanoma-Specific T Cells Using Microneedle Arrays Coated with Immune-Polyelectrolyte Multilayers
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 195–205
DOI: 10.1021/acsbiomaterials.6b00414

Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle Uptake and Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 206–213
DOI: 10.1021/acsbiomaterials.6b00473

Biomaterials-Based Vaccination Strategies for the Induction of CD8+T Cell Responses
This article is part of the Biomaterials for Immunoengineering special issue.
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 126–143
DOI: 10.1021/acsbiomaterials.6b00412

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ACS Catalysis

A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1025–1029
DOI: 10.1021/acscatal.6b03061

Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1432–1437
DOI: 10.1021/acscatal.6b03388

Breaking Amides using Nickel Catalysis
ACS Catal., 2017, 7 (2), pp 1413–1423
DOI: 10.1021/acscatal.6b03277

Metal–Metal Bonds in Catalysis
ACS Catal., 2017, 7 (2), pp 936–958
DOI: 10.1021/acscatal.6b02692

Catalytic Zirconium/Hafnium-Based Metal–Organic Frameworks
ACS Catal., 2017, 7 (2), pp 997–1014
DOI: 10.1021/acscatal.6b02923

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ACS Energy Letters

Electrochemical Capture and Release of Carbon Dioxide
Open access through ACS Editors’ Choice
ACS Energy Lett., 2017, 2 (2), pp 454–461
DOI: 10.1021/acsenergylett.6b00608

Advances and Obstacles on Perovskite Solar Cell Research from Material Properties to Photovoltaic Function
ACS Energy Lett., 2017, 2 (2), pp 520–523
DOI: 10.1021/acsenergylett.7b00085

Are You Making the Right Presentation at the Scientific Meeting?
ACS Energy Lett., 2017, 2 (2), pp 408–409
DOI: 10.1021/acsenergylett.7b00004

Next-Generation Solar Cells and Conversion of Solar Energy
ACS Energy Lett., 2017, 2 (2), pp 334–335
DOI: 10.1021/acsenergylett.6b00645

High-Efficiency Rubidium-Incorporated Perovskite Solar Cells by Gas Quenching
Open access through ACS AuthorChoice
ACS Energy Lett., 2017, 2 (2), pp 438–444
DOI: 10.1021/acsenergylett.6b00697

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ACS Macro Letters

Catalyst-Free Photoinduced End-Group Removal of Thiocarbonylthio Functionality
ACS Macro Lett., 2017, 6 (2), pp 185–189
DOI: 10.1021/acsmacrolett.7b00038

Pro-Antimicrobial Networks via Degradable Acetals (PANDAs) Using Thiol–Ene Photopolymerization
ACS Macro Lett., 2017, 6 (2), pp 171–175
DOI: 10.1021/acsmacrolett.7b00009

Chemical Synthesis of Multiblock Copolypeptides Inspired by Spider Dragline Silk Proteins
Open access through ACS AuthorChoice
ACS Macro Lett., 2017, 6 (2), pp 103–106
DOI: 10.1021/acsmacrolett.7b00006

2-Hydroxyethylcellulose and Amphiphilic Block Polymer Conjugates Form Mechanically Tunable and Nonswellable Hydrogels
ACS Macro Lett., 2017, 6 (2), pp 145–149
DOI: 10.1021/acsmacrolett.6b00954

Self-Assembled, Biodegradable Magnetic Resonance Imaging Agents: Organic Radical-Functionalized Diblock Copolymers
ACS Macro Lett., 2017, 6 (2), pp 176–180
DOI: 10.1021/acsmacrolett.6b00924

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ACS Nano

Nanoscience and Nanotechnology Cross Borders
ACS Nano, 2017, 11 (2), pp 1123–1126
DOI: 10.1021/acsnano.7b00953

Urea-Hydroxyapatite Nanohybrids for Slow Release of Nitrogen
Open access through ACS Editors’ Choice
ACS Nano, 2017, 11 (2), pp 1214–1221
DOI: 10.1021/acsnano.6b07781

Arbitrary-Shaped Graphene-Based Planar Sandwich Supercapacitors on One Substrate with Enhanced Flexibility and Integration
ACS Nano, 2017, 11 (2), pp 2171–2179
DOI: 10.1021/acsnano.6b08435

Tumor-Penetrating Nanoparticles for Enhanced Anticancer Activity of Combined Photodynamic and Hypoxia-Activated Therapy
ACS Nano, 2017, 11 (2), pp 2227–2238
DOI: 10.1021/acsnano.6b08731

Salt-Templated Synthesis of 2D Metallic MoN and Other Nitrides
ACS Nano, 2017, 11 (2), pp 2180–2186
DOI: 10.1021/acsnano.6b08534

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ACS Photonics

Visible Light, Wide-Angle Graded Metasurface for Back Reflection
ACS Photonics, 2017, 4 (2), pp 228–235
DOI: 10.1021/acsphotonics.6b00965

Optimization of Nanoparticle-Based SERS Substrates through Large-Scale Realistic Simulations
Open access through ACS Editors’ Choice
ACS Photonics, 2017, 4 (2), pp 329–337
DOI: 10.1021/acsphotonics.6b00786

Light Outcoupling from Quantum Dot-Based Microdisk Laser via Plasmonic Nanoantenna
ACS Photonics, 2017, 4 (2), pp 275–281
DOI: 10.1021/acsphotonics.6b00552

All-Optical Pattern Recognition and Image Processing on a Metamaterial Beam Splitter
Open access through ACS AuthorChoice
ACS Photonics, 2017, 4 (2), pp 217–222
DOI: 10.1021/acsphotonics.6b00921

Tunable Full-Color Electroluminescence from All-Organic Optical Upconversion Devices by Near-Infrared Sensing
ACS Photonics, 2017, 4 (2), pp 223–227
DOI: 10.1021/acsphotonics.6b00964

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ACS Sensors

Single-Step DNA Detection Assay Monitoring Dual-Color Light Scattering from Individual Metal Nanoparticle Aggregates

Open access through ACS AuthorChoice

ACS Sens., 2017, 2 (2), pp 251–256
DOI: 10.1021/acssensors.6b00737

Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
ACS Sens., 2017, 2 (2), pp 243–250
DOI: 10.1021/acssensors.6b00664

What Are Clinically Relevant Levels of Cellular and Biomolecular Analytes?
ACS Sens., 2017, 2 (2), pp 193–197
DOI: 10.1021/acssensors.6b00691

An Ultrasensitive Plasmonic Nanosensor for Aldehydes
ACS Sens., 2017, 2 (2), pp 263–267
DOI: 10.1021/acssensors.6b00769

Inflection Point of the Localized Surface Plasmon Resonance Peak: A General Method to Improve the Sensitivity
ACS Sens., 2017, 2 (2), pp 235–242
DOI: 10.1021/acssensors.6b00633

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ACS Sustainable Chemistry & Engineering

Use of Bisulfite Processing To Generate High-β-O-4 Content Water-Soluble Lignosulfonates
Open access through ACS Editors’ Choice
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1831–1839
DOI: 10.1021/acssuschemeng.6b02566

Highly Efficient Visible-Light-Induced Photoactivity of Z-Scheme g-C3N4/Ag/MoS2 Ternary Photocatalysts for Organic Pollutant Degradation and Production of Hydrogen
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1436–1445
DOI: 10.1021/acssuschemeng.6b02010

Smart Design of Self-Assembled Mesoporous α-FeOOH Nanoparticles: High-Surface-Area Sorbent for Hg2+ from Wastewater
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1272–1279
DOI: 10.1021/acssuschemeng.6b00937

Chemically Modified Cellulose Filter Paper for Heavy Metal Remediation in Water
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1965–1973
DOI: 10.1021/acssuschemeng.6b02768

Nitrogen-Doped Graphene as a Robust Scaffold for the Homogeneous Deposition of Copper Nanostructures: A Nonenzymatic Disposable Glucose Sensor
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1648–1658
DOI: 10.1021/acssuschemeng.6b02390

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Bioconjugate Chemistry

Quantitative Conjugated Payload Measurement Using Enzymatic Release of Antibody–Drug Conjugate with Cleavable Linker
Bioconjugate Chem., 2017, 28 (2), pp 620–626
DOI: 10.1021/acs.bioconjchem.6b00695

Peptide-Based Stealth Nanoparticles for Targeted and pH-Triggered Delivery
Bioconjugate Chem., 2017, 28 (2), pp 627–635
DOI: 10.1021/acs.bioconjchem.6b00701

Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates
Bioconjugate Chem., 2017, 28 (2), pp 371–381
DOI: 10.1021/acs.bioconjchem.6b00530

Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes
Bioconjugate Chem., 2017, 28 (2), pp 341–352
DOI: 10.1021/acs.bioconjchem.6b00433

Automated, Resin-Based Method to Enhance the Specific Activity of Fluorine-18 Clicked PET Radiotracers
Bioconjugate Chem., 2017, 28 (2), pp 583–589
DOI: 10.1021/acs.bioconjchem.6b00678

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Biomacromolecules

Hydrogels for Therapeutic Delivery: Current Developments and Future Directions
Biomacromolecules, 2017, 18 (2), pp 316–330
DOI: 10.1021/acs.biomac.6b01604

Luminescent Difluoroboron β-Diketonate PLA–PEG Nanoparticle
Biomacromolecules, 2017, 18 (2), pp 551–561
DOI: 10.1021/acs.biomac.6b01708

Implantable Tin Porphyrin-PEG Hydrogels with pH-Responsive Fluorescence
Biomacromolecules, 2017, 18 (2), pp 562–567
DOI: 10.1021/acs.biomac.6b01715

Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides
Biomacromolecules, 2017, 18 (2), pp 599–609
DOI: 10.1021/acs.biomac.6b01759

“Clickable” Nanogels via Thermally Driven Self-Assembly of Polymers: Facile Access to Targeted Imaging Platforms using Thiol–Maleimide Conjugation
Biomacromolecules, 2017, 18 (2), pp 490–497
DOI: 10.1021/acs.biomac.6b01576

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Chemistry of Materials

Nucleation, Growth, and Structural Transformations of Perovskite Nanocrystals
Chem. Mater., 2017, 29 (3), pp 1302–1308
DOI: 10.1021/acs.chemmater.6b04841

Facile Soft-Templated Synthesis of High-Surface Area and Highly Porous Carbon Nitrides
Chem. Mater., 2017, 29 (4), pp 1496–1506
DOI: 10.1021/acs.chemmater.6b03570

Hard X-ray Photon-in Photon-out Spectroscopy as a Probe of the Temperature-Induced Delocalization of Electrons in Nanoscale Semiconductors
Open access through ACS Editors’ Choice
Chem. Mater., 2017, 29 (4), pp 1461–1466
DOI: 10.1021/acs.chemmater.6b05218

High-Yield Alkylation and Arylation of Graphene via Grignard Reaction with Fluorographene
Open access through ACS AuthorChoice
Chem. Mater., 2017, 29 (3), pp 926–930
DOI: 10.1021/acs.chemmater.6b05040

Molecular Design of Highly Efficient Thermally Activated Delayed Fluorescence Hosts for Blue Phosphorescent and Fluorescent Organic Light-Emitting Diodes
Chem. Mater., 2017, 29 (4), pp 1527–1537
DOI: 10.1021/acs.chemmater.6b03979

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Crystal Growth & Design

Molecular Design of Zirconium Tetrazolate Metal–Organic Frameworks for CO2 Capture
Cryst. Growth Des., 2017, 17 (2), pp 543–549
DOI: 10.1021/acs.cgd.6b01405

Comparative Stability and Sorption Study of Two the-type Metal–Organic Frameworks with Different Multiplicate Metal–Ligand Interactions in Secondary Building Units
Cryst. Growth Des., 2017, 17 (2), pp 418–422
DOI: 10.1021/acs.cgd.6b01716

Nonlinear Optical Rod Indium-Imidazoledicarboxylate Framework as Room-Temperature Gas Sensor for Butanol Isomers
Cryst. Growth Des., 2017, 17 (2), pp 423–427
DOI: 10.1021/acs.cgd.6b01744

Various Polycarboxylate-Directed Cd(II) Coordination Polymers Based on a Semirigid Bis-pyridyl-bis-amide Ligand: Construction and Fluorescent and Photocatalytic Properties
Cryst. Growth Des., 2017, 17 (2), pp 483–496
DOI: 10.1021/acs.cgd.6b01299

Carborane Bis-pyridylalcohols as Linkers for Coordination Polymers: Synthesis, Crystal Structures, and Guest-Framework Dependent Mechanical Properties
Cryst. Growth Des., 2017, 17 (2), pp 846–857
DOI: 10.1021/acs.cgd.6b01682

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Energy & Fuels

Simulation of Asphaltene Aggregation through Molecular Dynamics: Insights and Limitations
Open access through ACS AuthorChoice
Energy Fuels, 2017, 31 (2), pp 1108–1125
DOI: 10.1021/acs.energyfuels.6b02161

Chemical Kinetic Insights into the Octane Number and Octane Sensitivity of Gasoline Surrogate Mixtures
Energy Fuels, 2017, 31 (2), pp 1945–1960
DOI: 10.1021/acs.energyfuels.6b02659

Segregation of Amphiphilic Polymer-Coated Nanoparticles to Bicontinuous Oil/Water Microemulsion Phases
Energy Fuels, 2017, 31 (2), pp 1339–1346
DOI: 10.1021/acs.energyfuels.6b02687

Techno-economic Analysis of Metal–Organic Frameworks for Hydrogen and Natural Gas Storage
Energy Fuels, 2017, 31 (2), pp 2024–2032
DOI: 10.1021/acs.energyfuels.6b02510

New Composite Viscosity Reducer with Both Asphaltene Dispersion and Emulsifying Capability for Heavy and Ultraheavy Crude Oils
Energy Fuels, 2017, 31 (2), pp 1159–1173
DOI: 10.1021/acs.energyfuels.6b02265

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Industrial & Engineering Chemistry Research 

Biomimetic Superhydrophobic Engineering Metal Surface with Hierarchical Structure and Tunable Adhesion: Design of Microscale Pattern
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (4), pp 907–919
DOI: 10.1021/acs.iecr.6b03936

An Effective Biocatalytic Reactor–Rotating Packed Bed Applied in Hydrolysis Reactions
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (5), pp 1349–1353
DOI: 10.1021/acs.iecr.6b03381

Comprehensive Analysis of Sorption Enhanced Steam Methane Reforming in a Variable Volume Membrane Reactor
Ind. Eng. Chem. Res., 2017, 56 (7), pp 1758–1771
DOI: 10.1021/acs.iecr.6b04392

Zeolitic Imidazolate Framework-8 (ZIF-8) Membranes for Kr/Xe Separation
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1682–1686
DOI: 10.1021/acs.iecr.6b04868

Facile Synthesis and Direct Activation of Zirconium Based Metal–Organic Frameworks from Acetone
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1478–1484
DOI: 10.1021/acs.iecr.6b04361

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Inorganic Chemistry

Activating Fe(I) Porphyrins for the Hydrogen Evolution Reaction Using Second-Sphere Proton Transfer Residues
Inorg. Chem., 2017, 56 (4), pp 1783–1793
DOI: 10.1021/acs.inorgchem.6b01707

Bifunctional Imidazolium-Based Ionic Liquid Decorated UiO-67 Type MOF for Selective CO2 Adsorption and Catalytic Property for CO2 Cycloaddition with Epoxides
Inorg. Chem., 2017, 56 (4), pp 2337–2344
DOI: 10.1021/acs.inorgchem.6b03169

Green Synthesis of Zr-CAU-28: Structure and Properties of the First Zr-MOF Based on 2,5-Furandicarboxylic Acid
Inorg. Chem., 2017, 56 (4), pp 2270–2277
DOI: 10.1021/acs.inorgchem.6b02969

Photoluminescent and Slow Magnetic Relaxation Studies on Lanthanide(III)-2,5-pyrazinedicarboxylate Frameworks
Inorg. Chem., 2017, 56 (4), pp 2108–2123
DOI: 10.1021/acs.inorgchem.6b02774

Water-Stable In(III)-Based Metal–Organic Frameworks with Rod-Shaped Secondary Building Units: Single-Crystal to Single-Crystal Transformation and Selective Sorption of C2H2 over CO2 and CH4
Inorg. Chem., 2017, 56 (4), pp 2188–2197
DOI: 10.1021/acs.inorgchem.6b02840

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Journal of Chemical & Engineering Data

The Viscosity and Density of Ionic Liquid + Tetraglyme Mixtures and the Effect of Tetraglyme on CO2 Solubility
J. Chem. Eng. Data, 2017, 62 (2), pp 608–622
DOI: 10.1021/acs.jced.6b00596

Evaluating Characteristic Parameters for Carbon Dioxide in the Sanchez–Lacombe Equation of State
J. Chem. Eng. Data, 2017, 62 (2), pp 585–595
DOI: 10.1021/acs.jced.6b00743

Correction to “Measurement and Correlation of 1,4-Naphthoquinone and of Plumbagin Solubilities in Supercritical Carbon Dioxide”
J. Chem. Eng. Data, 2017, 62 (2), pp 886–887
DOI: 10.1021/acs.jced.7b00025

Thermodynamic Study of Methylene Blue Adsorption on Carbon Nanotubes Using Isothermal Titration Calorimetry: A Simple and Rigorous Approach
J. Chem. Eng. Data, 2017, 62 (2), pp 729–737
DOI: 10.1021/acs.jced.6b00804

Correction to “Liquid–Liquid Equilibria in Aqueous Mixtures of Alkylmethylimidazolium Glutamate with Potassium Carbonate and Some Physicochemical Properties of Aqueous [Cnmim][Glu] (n = 4, 6, 8) Solutions”
J. Chem. Eng. Data, 2017, 62 (2), pp 885–885
DOI: 10.1021/acs.jced.6b00906

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The Journal of Physical Chemistry C

Photon Reabsorption in Mixed CsPbCl3:CsPbI3 Perovskite Nanocrystal Films for Light-Emitting Diodes
J. Phys. Chem. C, 2017, 121 (7), pp 3790–3796
DOI: 10.1021/acs.jpcc.6b12828

Light-Induced Degradation of CH3NH3PbI3 Hybrid Perovskite Thin Film
J. Phys. Chem. C, 2017, 121 (7), pp 3904–3910
DOI: 10.1021/acs.jpcc.6b11853

Ag Doping of Organometal Lead Halide Perovskites: Morphology Modification and p-Type Character
J. Phys. Chem. C, 2017, 121 (7), pp 3673–3679
DOI: 10.1021/acs.jpcc.6b09722

Control of Symmetry Breaking Size and Aspect Ratio in Gold Nanorods: Underlying Role of Silver Nitrate
J. Phys. Chem. C, 2017, 121 (6), pp 3549–3559
DOI: 10.1021/acs.jpcc.6b10343

Tunable Structural, Electronic, and Optical Properties of Layered Two-Dimensional C2N and MoS2 van der Waals Heterostructure as Photovoltaic Material
J. Phys. Chem. C, 2017, 121 (6), pp 3654–3660
DOI: 10.1021/acs.jpcc.6b12681

***

The Journal of Physical Chemistry Letters

Charge Carrier Trapping at Surface Defects of Perovskite Solar Cell Absorbers: A First-Principles Study
Open access through ACS Editors’ Choice
J. Phys. Chem. Lett., 2017, 8 (4), pp 742–746
DOI: 10.1021/acs.jpclett.7b00055

Cs2InAgCl6: A New Lead-Free Halide Double Perovskite with Direct Band Gap
J. Phys. Chem. Lett., 2017, 8 (4), pp 772–778
DOI: 10.1021/acs.jpclett.6b02682

Spectroscopic Evidences for Strong Hydrogen Bonds with Selenomethionine in Proteins
J. Phys. Chem. Lett., 2017, 8 (4), pp 794–800
DOI: 10.1021/acs.jpclett.6b02931

Electron Transfer from Triplet State of TIPS-Pentacene Generated by Singlet Fission Processes to CH3NH3PbI3 Perovskite
J. Phys. Chem. Lett., 2017, 8 (4), pp 884–888
DOI: 10.1021/acs.jpclett.7b00072

First-Principles Study of Novel Two-Dimensional (C4H9NH3)2PbX4 Perovskites for Solar Cell Absorbers
J. Phys. Chem. Lett., 2017, 8 (4), pp 876–883
DOI: 10.1021/acs.jpclett.7b00003

***

Langmuir

Large-Scale, Facile Transfer of Oleic Acid-Stabilized Iron Oxide Nanoparticles to the Aqueous Phase for Biological Applications
Langmuir, 2017, 33 (7), pp 1662–1669
DOI: 10.1021/acs.langmuir.6b03360

Preparation of Superwetting Porous Materials for Ultrafast Separation of Water-in-Oil Emulsions
Langmuir, 2017, 33 (8), pp 1969–1973
DOI: 10.1021/acs.langmuir.6b04344

Molecular Understanding on the Underwater Oleophobicity of Self-Assembled Monolayers: Zwitterionic versus Nonionic
Langmuir, 2017, 33 (7), pp 1732–1741
DOI: 10.1021/acs.langmuir.6b03988

Controlling the Structure of Supraballs by pH-Responsive Particle Assembly
Langmuir, 2017, 33 (8), pp 1995–2002
DOI: 10.1021/acs.langmuir.6b04648

Controlling the Rheology of Montmorillonite Stabilized Oil-in-Water Emulsions
Open access through ACS AuthorChoice
Langmuir, 2017, 33 (7), pp 1679–1686
DOI: 10.1021/acs.langmuir.6b04161

***

Macromolecules

50th Anniversary Perspective: Polymers with Complex Architectures
Macromolecules, 2017, 50 (4), pp 1253–1290
DOI: 10.1021/acs.macromol.6b02569

50th Anniversary Perspective: Are Polymer Nanocomposites Practical for Applications?
Macromolecules, 2017, 50 (3), pp 714–731
DOI: 10.1021/acs.macromol.6b02330

Tuning Hydrophobicity To Program Block Copolymer Assemblies from the Inside Out
Macromolecules, 2017, 50 (3), pp 935–943
DOI: 10.1021/acs.macromol.6b02754

Self-Accelerating Click Reaction for Cyclic Polymer
Macromolecules, 2017, 50 (4), pp 1463–1472
DOI: 10.1021/acs.macromol.6b02614

Phototunable Thermoplastic Elastomer Hydrogel Networks
Macromolecules, 2017, 50 (4), pp 1331–1341
DOI: 10.1021/acs.macromol.6b02005

***

Nano Letters

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species
Nano Lett., 2017, 17 (2), pp 928–937
DOI: 10.1021/acs.nanolett.6b04269

Photocatalytic Color Switching of Transition Metal Hexacyanometalate Nanoparticles for High-Performance Light-Printable Rewritable Paper
Nano Lett., 2017, 17 (2), pp 755–761
DOI: 10.1021/acs.nanolett.6b03909

Structure-Sensitive CO2 Electroreduction to Hydrocarbons on Ultrathin 5-fold Twinned Copper Nanowires
Nano Lett., 2017, 17 (2), pp 1312–1317
DOI: 10.1021/acs.nanolett.6b05287

Interlayer Exciton Optoelectronics in a 2D Heterostructure p–n Junction
Nano Lett., 2017, 17 (2), pp 638–643
DOI: 10.1021/acs.nanolett.6b03398

Two-Dimensional SnO Anodes with a Tunable Number of Atomic Layers for Sodium Ion Batteries
Nano Lett., 2017, 17 (2), pp 1302–1311
DOI: 10.1021/acs.nanolett.6b05280

 

Discover the Most-Read Biological Chemistry Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read biological chemistry articles that appeared in  relevant ACS Publications journals in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
***

ACS Biomaterials Science & Engineering

Editorial: Special Issue on Biomaterials for Immunoengineering
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 106–107
DOI: 10.1021/acsbiomaterials.7b00049

Polymers for DNA Vaccine Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 108–125
DOI: 10.1021/acsbiomaterials.6b00418

In Vivo Expansion of Melanoma-Specific T Cells Using Microneedle Arrays Coated with Immune-Polyelectrolyte Multilayers
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 195–205
DOI: 10.1021/acsbiomaterials.6b00414

Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle Uptake and Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 206–213
DOI: 10.1021/acsbiomaterials.6b00473

Biomaterials-Based Vaccination Strategies for the Induction of CD8+T Cell Responses
This article is part of the Biomaterials for Immunoengineering special issue.
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 126–143
DOI: 10.1021/acsbiomaterials.6b00412

***

ACS Catalysis

A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1025–1029
DOI: 10.1021/acscatal.6b03061

Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins
Open access through ACS Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1432–1437
DOI: 10.1021/acscatal.6b03388

Breaking Amides using Nickel Catalysis
ACS Catal., 2017, 7 (2), pp 1413–1423
DOI: 10.1021/acscatal.6b03277

Metal–Metal Bonds in Catalysis
ACS Catal., 2017, 7 (2), pp 936–958
DOI: 10.1021/acscatal.6b02692

Catalytic Zirconium/Hafnium-Based Metal–Organic Frameworks
ACS Catal., 2017, 7 (2), pp 997–1014
DOI: 10.1021/acscatal.6b02923

***

ACS Chemical Biology

Chemical Modifications to RNA: A New Layer of Gene Expression Regulation
ACS Chem. Biol., 2017, 12 (2), pp 316–325
DOI: 10.1021/acschembio.6b00960

Deciphering the Functions of Protein O-GlcNAcylation with Chemistry
ACS Chem. Biol., 2017, 12 (2), pp 326–335
DOI: 10.1021/acschembio.6b01065

Duration Control of Protein Expression in Vivo by Light-Mediated Reversible Activation of Translation
ACS Chem. Biol., 2017, 12 (2), pp 351–356
DOI: 10.1021/acschembio.6b00684

Engineering High Affinity Protein–Protein Interactions Using a High-Throughput Microcapillary Array Platform
ACS Chem. Biol., 2017, 12 (2), pp 336–341
DOI: 10.1021/acschembio.6b00794

Development of an Azoreductase-based Reporter System with Synthetic Fluorogenic Substrates
ACS Chem. Biol., 2017, 12 (2), pp 558–563
DOI: 10.1021/acschembio.6b00852

***

ACS Chemical Neuroscience

Hitchhiker’s Guide to Voltammetry: Acute and Chronic Electrodes for in Vivo Fast-Scan Cyclic Voltammetry
Open access through ACS Editors’ Choice
ACS Chem. Neurosci., 2017, 8 (2), pp 221–234
DOI: 10.1021/acschemneuro.6b00393

Differentiating Siblings: The Case of Dopamine and Norepinephrine
ACS Chem. Neurosci., 2017, 8 (2), pp 218–220
DOI: 10.1021/acschemneuro.7b00056

Monitoring Molecules in Neuroscience Then and Now
ACS Chem. Neurosci., 2017, 8 (2), pp 215–217
DOI: 10.1021/acschemneuro.7b00043

Probing Deep Brain Circuitry: New Advances in in Vivo Calcium Measurement Strategies
ACS Chem. Neurosci., 2017, 8 (2), pp 243–251
DOI: 10.1021/acschemneuro.6b00307

Why Monitor Molecules in Neuroscience?
This article is part of the Monitoring Molecules in Neuroscience 2016 special issue.
ACS Chem. Neurosci., 2017, 8 (2), pp 211–212
DOI: 10.1021/acschemneuro.7b00052

***

ACS Infectious Diseases

Introducing a New Associate Editor for ACS Infectious Diseases
ACS Infect. Dis., 2017, 3 (2), pp 110–110
DOI: 10.1021/acsinfecdis.7b00018

Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome
ACS Infect. Dis., 2017, 3 (2), pp 176–181
DOI: 10.1021/acsinfecdis.6b00172

Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors
ACS Infect. Dis., 2017, 3 (2), pp 152–161
DOI: 10.1021/acsinfecdis.6b00148

A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs
ACS Infect. Dis., 2017, 3 (2), pp 119–131
DOI: 10.1021/acsinfecdis.5b00141

A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions
ACS Infect. Dis., 2017, 3 (2), pp 112–118
DOI: 10.1021/acsinfecdis.6b00079

***

ACS Medicinal Chemistry Letters

Communicating Our Science to Our Customers: Drug Discovery in Five Simple Experiments.
ACS Med. Chem. Lett., 2017, 8 (2), pp 143–144
DOI: 10.1021/acsmedchemlett.7b00015

Intramolecular Hydrogen Bond Expectations in Medicinal Chemistry
ACS Med. Chem. Lett., 2017, 8 (2), pp 139–142
DOI: 10.1021/acsmedchemlett.7b00002

Design and Synthesis of Novel, Selective GPR40 AgoPAMs
ACS Med. Chem. Lett., 2017, 8 (2), pp 221–226
DOI: 10.1021/acsmedchemlett.6b00443

Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2
ACS Med. Chem. Lett., 2017, 8 (2), pp 256–260
DOI: 10.1021/acsmedchemlett.6b00486

Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
ACS Med. Chem. Lett., 2017, 8 (2), pp 239–244
DOI: 10.1021/acsmedchemlett.6b00464

***

ACS Synthetic Biology

Introducing Our Authors
ACS Synth. Biol., 2017, 6 (2), pp 174–181
DOI: 10.1021/acssynbio.7b00038

Engineering of Taxadiene Synthase for Improved Selectivity and Yield of a Key Taxol Biosynthetic Intermediate
ACS Synth. Biol., 2017, 6 (2), pp 201–205
DOI: 10.1021/acssynbio.6b00206

Controlling Citrate Synthase Expression by CRISPR/Cas9 Genome Editing for n-Butanol Production in Escherichia coli
ACS Synth. Biol., 2017, 6 (2), pp 182–189
DOI: 10.1021/acssynbio.6b00134

Discovery of a Phosphonoacetic Acid Derived Natural Product by Pathway Refactoring
ACS Synth. Biol., 2017, 6 (2), pp 217–223
DOI: 10.1021/acssynbio.6b00299

A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases
ACS Synth. Biol., 2017, 6 (2), pp 326–333
DOI: 10.1021/acssynbio.6b00188

 ***

Biochemistry

Retraction of “β-Amyloid and α-Synuclein Cooperate To Block SNARE-Dependent Vesicle Fusion”
Biochemistry, 2017, 56 (7), pp 1026–1026
DOI: 10.1021/acs.biochem.7b00054

Interaction of Zika Virus Envelope Protein with Glycosaminoglycans
Biochemistry, 2017, 56 (8), pp 1151–1162
DOI: 10.1021/acs.biochem.6b01056

Cyclotide Structure and Function: The Role of Membrane Binding and Permeation
Biochemistry, 2017, 56 (5), pp 669–682
DOI: 10.1021/acs.biochem.6b01212

Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting
Open access through ACS AuthorChoice
Biochemistry, 2017, 56 (7), pp 957–970
DOI: 10.1021/acs.biochem.6b00888

Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules
Biochemistry, 2017, 56 (5), pp 683–691
DOI: 10.1021/acs.biochem.6b01060

***

Bioconjugate Chemistry

Quantitative Conjugated Payload Measurement Using Enzymatic Release of Antibody–Drug Conjugate with Cleavable Linker
Bioconjugate Chem., 2017, 28 (2), pp 620–626
DOI: 10.1021/acs.bioconjchem.6b00695

Peptide-Based Stealth Nanoparticles for Targeted and pH-Triggered Delivery
Bioconjugate Chem., 2017, 28 (2), pp 627–635
DOI: 10.1021/acs.bioconjchem.6b00701

Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates
Bioconjugate Chem., 2017, 28 (2), pp 371–381
DOI: 10.1021/acs.bioconjchem.6b00530

Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes
Bioconjugate Chem., 2017, 28 (2), pp 341–352
DOI: 10.1021/acs.bioconjchem.6b00433

Automated, Resin-Based Method to Enhance the Specific Activity of Fluorine-18 Clicked PET Radiotracers
Bioconjugate Chem., 2017, 28 (2), pp 583–589
DOI: 10.1021/acs.bioconjchem.6b00678

***

Biomacromolecules

Hydrogels for Therapeutic Delivery: Current Developments and Future Directions
Biomacromolecules, 2017, 18 (2), pp 316–330
DOI: 10.1021/acs.biomac.6b01604

Luminescent Difluoroboron β-Diketonate PLA–PEG Nanoparticle
Biomacromolecules, 2017, 18 (2), pp 551–561
DOI: 10.1021/acs.biomac.6b01708

Implantable Tin Porphyrin-PEG Hydrogels with pH-Responsive Fluorescence
Biomacromolecules, 2017, 18 (2), pp 562–567
DOI: 10.1021/acs.biomac.6b01715

Phase Behavior and Self-Assembly of Perfectly Sequence-Defined and Monodisperse Multiblock Copolypeptides
Biomacromolecules, 2017, 18 (2), pp 599–609
DOI: 10.1021/acs.biomac.6b01759

“Clickable” Nanogels via Thermally Driven Self-Assembly of Polymers: Facile Access to Targeted Imaging Platforms using Thiol–Maleimide Conjugation
Biomacromolecules, 2017, 18 (2), pp 490–497
DOI: 10.1021/acs.biomac.6b01576

***

Journal of Agricultural and Food Chemistry

Development of a QuEChERS-Based Method for the Simultaneous Determination of Acidic Pesticides, Their Esters, and Conjugates Following Alkaline Hydrolysis
J. Agric. Food Chem., 2017, 65 (6), pp 1296–1305
DOI: 10.1021/acs.jafc.6b05407

Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
Open access through ACS Editors’ Choice
J. Agric. Food Chem., 2017, 65 (4), pp 752–758
DOI: 10.1021/acs.jafc.6b04538

Analytical Methods Used in the Quality Control of Honey
J. Agric. Food Chem., 2017, 65 (4), pp 690–703
DOI: 10.1021/acs.jafc.6b04776

A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer’s Disease
J. Agric. Food Chem., 2017, 65 (5), pp 1005–1020
DOI: 10.1021/acs.jafc.6b04398

Chemical and Antioxidant Properties of Betalains
J. Agric. Food Chem., 2017, 65 (4), pp 675–689
DOI: 10.1021/acs.jafc.6b04208

 ***

Journal of Chemical Theory and Computation

Multireference Perturbation Theory with Cholesky Decomposition for the Density Matrix Renormalization Group
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 451–459
DOI: 10.1021/acs.jctc.6b00778

Quantitative Assessment of Molecular Dynamics Sampling for Flexible Systems
J. Chem. Theory Comput., 2017, 13 (2), pp 400–414
DOI: 10.1021/acs.jctc.6b00823

Systematic Quantum Mechanical Region Determination in QM/MM Simulation
J. Chem. Theory Comput., 2017, 13 (2), pp 563–576
DOI: 10.1021/acs.jctc.6b01049

Modeling Diversity in Structures of Bacterial Outer Membrane Lipids
J. Chem. Theory Comput., 2017, 13 (2), pp 811–824
DOI: 10.1021/acs.jctc.6b00856

A Monte Carlo Resampling Approach for the Calculation of Hybrid Classical and Quantum Free Energies
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 415–424
DOI: 10.1021/acs.jctc.6b00506

***

Journal of Medicinal Chemistry

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
J. Med. Chem., 2017, 60 (4), pp 1247–1261
DOI: 10.1021/acs.jmedchem.6b01751

Recent Advances in Scaffold Hopping
J. Med. Chem., 2017, 60 (4), pp 1238–1246
DOI: 10.1021/acs.jmedchem.6b01437

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
J. Med. Chem., 2017, 60 (3), pp 839–885
DOI: 10.1021/acs.jmedchem.6b00788

Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A
J. Med. Chem., 2017, 60 (3), pp 1000–1017
DOI: 10.1021/acs.jmedchem.6b01329

Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
J. Med. Chem., 2017, 60 (3), pp 1060–1075
DOI: 10.1021/acs.jmedchem.6b01460

***

Journal of Natural Products

Diterpenoids and Lignans from Cephalotaxus fortunei
J. Nat. Prod., 2017, 80 (2), pp 356–362
DOI: 10.1021/acs.jnatprod.6b00802

Concise Syntheses of Hyrtioreticulins C and D via a C-4 Pictet–Spengler Reaction: Revised Signs of Specific Rotations
J. Nat. Prod., 2017, 80 (2), pp 241–245
DOI: 10.1021/acs.jnatprod.7b00008

Branimycins B and C, Antibiotics Produced by the Abyssal Actinobacterium Pseudonocardia carboxydivorans M-227
J. Nat. Prod., 2017, 80 (2), pp 569–573
DOI: 10.1021/acs.jnatprod.6b01107

Cultures of the Marine Bacterium Pseudovibrio denitrificans Ab134 Produce Bromotyrosine-Derived Alkaloids Previously Only Isolated from Marine Sponges
J. Nat. Prod., 2017, 80 (2), pp 235–240
DOI: 10.1021/acs.jnatprod.6b00838

Sesquiterpenoids with Various Carbocyclic Skeletons from the Flowers of Chrysanthemum indicum
J. Nat. Prod., 2017, 80 (2), pp 298–307
DOI: 10.1021/acs.jnatprod.6b00694

 ***

The Journal of Physical Chemistry B

Editorial – Virtual Issue of JPCB on Biophysics
J. Phys. Chem. B, 2017, 121 (5), pp 913–914
DOI: 10.1021/acs.jpcb.6b12749

Characterization of Nanocellulose Using Small-Angle Neutron, X-ray, and Dynamic Light Scattering Techniques
J. Phys. Chem. B, 2017, 121 (6), pp 1340–1351
DOI: 10.1021/acs.jpcb.6b11425

A Spectroscopic and Molecular Simulation Approach toward the Binding Affinity between Lysozyme and Phenazinium Dyes: An Effect on Protein Conformation
J. Phys. Chem. B, 2017, 121 (7), pp 1475–1484
DOI: 10.1021/acs.jpcb.6b10991

The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space
J. Phys. Chem. B, 2017, 121 (7), pp 1576–1586
DOI: 10.1021/acs.jpcb.7b00253

Coarse-Grained Molecular Simulation of the Hierarchical Self-Assembly of π-Conjugated Optoelectronic Peptides
J. Phys. Chem. B, 2017, 121 (7), pp 1684–1706
DOI: 10.1021/acs.jpcb.6b10165

 ***

The Journal of Physical Chemistry Letters

Charge Carrier Trapping at Surface Defects of Perovskite Solar Cell Absorbers: A First-Principles Study
Open access through ACS Editors’ Choice
J. Phys. Chem. Lett., 2017, 8 (4), pp 742–746
DOI: 10.1021/acs.jpclett.7b00055

Cs2InAgCl6: A New Lead-Free Halide Double Perovskite with Direct Band Gap
J. Phys. Chem. Lett., 2017, 8 (4), pp 772–778
DOI: 10.1021/acs.jpclett.6b02682

Spectroscopic Evidences for Strong Hydrogen Bonds with Selenomethionine in Proteins
J. Phys. Chem. Lett., 2017, 8 (4), pp 794–800
DOI: 10.1021/acs.jpclett.6b02931

Electron Transfer from Triplet State of TIPS-Pentacene Generated by Singlet Fission Processes to CH3NH3PbI3 Perovskite
J. Phys. Chem. Lett., 2017, 8 (4), pp 884–888
DOI: 10.1021/acs.jpclett.7b00072

First-Principles Study of Novel Two-Dimensional (C4H9NH3)2PbX4 Perovskites for Solar Cell Absorbers
J. Phys. Chem. Lett., 2017, 8 (4), pp 876–883
DOI: 10.1021/acs.jpclett.7b00003

***

Journal of Proteome Research

Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein
J. Proteome Res., 2017, 16 (2), pp 920–932
DOI: 10.1021/acs.jproteome.6b00873

The Cover Letter
J. Proteome Res., 2017, 16 (2), pp 367–367
DOI: 10.1021/acs.jproteome.6b01068

Analysis of Reproducibility of Proteome Coverage and Quantitation Using Isobaric Mass Tags (iTRAQ and TMT)
J. Proteome Res., 2017, 16 (2), pp 384–392
DOI: 10.1021/acs.jproteome.5b01154

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer
J. Proteome Res., 2017, 16 (2), pp 609–618
DOI: 10.1021/acs.jproteome.6b00698

Optimization of Acquisition and Data-Processing Parameters for Improved Proteomic Quantification by Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectrometry
J. Proteome Res., 2017, 16 (2), pp 738–747
DOI: 10.1021/acs.jproteome.6b00767

***

Molecular Pharmaceutics

Polymer–Drug Nanoparticles Combine Doxorubicin Carrier and Heparin Bioactivity Functionalities for Primary and Metastatic Cancer Treatment
Mol. Pharmaceutics, 2017, 14 (2), pp 513–522
DOI: 10.1021/acs.molpharmaceut.6b00979

Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract
Mol. Pharmaceutics, 2017, 14 (2), pp 345–358
DOI: 10.1021/acs.molpharmaceut.6b00641

Effect of Particle Size on Drug Loading and Release Kinetics of Gefitinib-Loaded PLGA Microspheres
Mol. Pharmaceutics, 2017, 14 (2), pp 459–467
DOI: 10.1021/acs.molpharmaceut.6b00896

Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
Mol. Pharmaceutics, 2017, 14 (2), pp 523–532
DOI: 10.1021/acs.molpharmaceut.6b01010

Self-Assembly PEGylation Retaining Activity (SPRA) Technology via a Host–Guest Interaction Surpassing Conventional PEGylation Methods of Proteins
Mol. Pharmaceutics, 2017, 14 (2), pp 368–376
DOI: 10.1021/acs.molpharmaceut.6b00678

Discover the Most-Read Applied Chemistry Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read applied chemistry articles that appeared in each a chemistry ACS Publications journal in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
***

ACS Applied Materials & Interfaces

Ruthenium(II) Complex Incorporated UiO-67 Metal–Organic Framework Nanoparticles for Enhanced Two-Photon Fluorescence Imaging and Photodynamic Cancer Therapy
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5699–5708
DOI: 10.1021/acsami.6b12469

Janus Membranes with Opposing Surface Wettability Enabling Oil-to-Water and Water-to-Oil Emulsification
ACS Appl. Mater. Interfaces, 2017, 9 (6), pp 5062–5066
DOI: 10.1021/acsami.7b00017

Preparation of NiCoP Hollow Quasi-Polyhedra and Their Electrocatalytic Properties for Hydrogen Evolution in Alkaline Solution
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5982–5991
DOI: 10.1021/acsami.6b14127

Biodegradable Neuro-Compatible Peptide Hydrogel Promotes Neurite Outgrowth, Shows Significant Neuroprotection, and Delivers Anti-Alzheimer Drug
ACS Appl. Mater. Interfaces, 2017, 9 (6), pp 5067–5076
DOI: 10.1021/acsami.6b12114

Continuous Flow Processing of ZIF-8 Membranes on Polymeric Porous Hollow Fiber Supports for CO2 Capture
ACS Appl. Mater. Interfaces, 2017, 9 (7), pp 5678–5682
DOI: 10.1021/acsami.6b16297

***

ACS Biomaterials Science & Engineering

Editorial: Special Issue on Biomaterials for Immunoengineering
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 106–107
DOI: 10.1021/acsbiomaterials.7b00049

Polymers for DNA Vaccine Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 108–125
DOI: 10.1021/acsbiomaterials.6b00418

In Vivo Expansion of Melanoma-Specific T Cells Using Microneedle Arrays Coated with Immune-Polyelectrolyte Multilayers
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 195–205
DOI: 10.1021/acsbiomaterials.6b00414

Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle Uptake and Delivery
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 206–213
DOI: 10.1021/acsbiomaterials.6b00473

Biomaterials-Based Vaccination Strategies for the Induction of CD8+T Cell Responses
This article is part of the Biomaterials for Immunoengineering special issue.
ACS Biomater. Sci. Eng., 2017, 3 (2), pp 126–143
DOI: 10.1021/acsbiomaterials.6b00412

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ACS Combinatorial Science

Synthesis of Novel 5,6-Disubstituted Pyrrolo [2,3-d]Pyrimidine-2,4-Diones Via One-Pot Three-Component Reactions
ACS Comb. Sci., 2017, 19 (2), pp 108–112
DOI: 10.1021/acscombsci.6b00147

Rationally Designed Peptides and Peptidomimetics as Inhibitors of Amyloid-β (Aβ) Aggregation: Potential Therapeutics of Alzheimer’s Disease
ACS Comb. Sci., 2017, 19 (2), pp 55–80
DOI: 10.1021/acscombsci.6b00116

Neural-Network-Biased Genetic Algorithms for Materials Design: Evolutionary Algorithms That Learn
ACS Comb. Sci., 2017, 19 (2), pp 96–107
DOI: 10.1021/acscombsci.6b00136

Combining a Ru(II) “Building Block” and Rapid Screening Approach to Identify DNA Structure-Selective “Light Switch” Compounds
ACS Comb. Sci., 2017, 19 (2), pp 85–95
DOI: 10.1021/acscombsci.6b00119

Fluorophore Metal–Organic Complexes: High-Throughput Optical Screening for Aprotic Electrochemical Systems
ACS Comb. Sci., 2017, 19 (2), pp 81–84
DOI: 10.1021/acscombsci.6b00171

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ACS Energy Letters

Electrochemical Capture and Release of Carbon Dioxide
Open access through ACS Editors’ Choice
ACS Energy Lett., 2017, 2 (2), pp 454–461
DOI: 10.1021/acsenergylett.6b00608

Advances and Obstacles on Perovskite Solar Cell Research from Material Properties to Photovoltaic Function
ACS Energy Lett., 2017, 2 (2), pp 520–523
DOI: 10.1021/acsenergylett.7b00085

Are You Making the Right Presentation at the Scientific Meeting?
ACS Energy Lett., 2017, 2 (2), pp 408–409
DOI: 10.1021/acsenergylett.7b00004

Next-Generation Solar Cells and Conversion of Solar Energy
ACS Energy Lett., 2017, 2 (2), pp 334–335
DOI: 10.1021/acsenergylett.6b00645

High-Efficiency Rubidium-Incorporated Perovskite Solar Cells by Gas Quenching
Open access through ACS AuthorChoice
ACS Energy Lett., 2017, 2 (2), pp 438–444
DOI: 10.1021/acsenergylett.6b00697

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ACS Infectious Diseases

Introducing a New Associate Editor for ACS Infectious Diseases
ACS Infect. Dis., 2017, 3 (2), pp 110–110
DOI: 10.1021/acsinfecdis.7b00018

Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome
ACS Infect. Dis., 2017, 3 (2), pp 176–181
DOI: 10.1021/acsinfecdis.6b00172

Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors
ACS Infect. Dis., 2017, 3 (2), pp 152–161
DOI: 10.1021/acsinfecdis.6b00148

A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs
ACS Infect. Dis., 2017, 3 (2), pp 119–131
DOI: 10.1021/acsinfecdis.5b00141

A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions
ACS Infect. Dis., 2017, 3 (2), pp 112–118
DOI: 10.1021/acsinfecdis.6b00079

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ACS Medicinal Chemistry Letters

Communicating Our Science to Our Customers: Drug Discovery in Five Simple Experiments.
ACS Med. Chem. Lett., 2017, 8 (2), pp 143–144
DOI: 10.1021/acsmedchemlett.7b00015

Intramolecular Hydrogen Bond Expectations in Medicinal Chemistry
ACS Med. Chem. Lett., 2017, 8 (2), pp 139–142
DOI: 10.1021/acsmedchemlett.7b00002

Design and Synthesis of Novel, Selective GPR40 AgoPAMs
ACS Med. Chem. Lett., 2017, 8 (2), pp 221–226
DOI: 10.1021/acsmedchemlett.6b00443

Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2
ACS Med. Chem. Lett., 2017, 8 (2), pp 256–260
DOI: 10.1021/acsmedchemlett.6b00486

Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
ACS Med. Chem. Lett., 2017, 8 (2), pp 239–244
DOI: 10.1021/acsmedchemlett.6b00464

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ACS Sensors

Single-Step DNA Detection Assay Monitoring Dual-Color Light Scattering from Individual Metal Nanoparticle Aggregates
Open access through ACS AuthorChoice
ACS Sens., 2017, 2 (2), pp 251–256
DOI: 10.1021/acssensors.6b00737

Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
ACS Sens., 2017, 2 (2), pp 243–250
DOI: 10.1021/acssensors.6b00664

What Are Clinically Relevant Levels of Cellular and Biomolecular Analytes?
ACS Sens., 2017, 2 (2), pp 193–197
DOI: 10.1021/acssensors.6b00691

An Ultrasensitive Plasmonic Nanosensor for Aldehydes
ACS Sens., 2017, 2 (2), pp 263–267
DOI: 10.1021/acssensors.6b00769

Inflection Point of the Localized Surface Plasmon Resonance Peak: A General Method to Improve the Sensitivity
ACS Sens., 2017, 2 (2), pp 235–242
DOI: 10.1021/acssensors.6b00633

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ACS Sustainable Chemistry & Engineering

Use of Bisulfite Processing To Generate High-β-O-4 Content Water-Soluble Lignosulfonates
Open access through ACS Editors’ Choice
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1831–1839
DOI: 10.1021/acssuschemeng.6b02566

Highly Efficient Visible-Light-Induced Photoactivity of Z-Scheme g-C3N4/Ag/MoS2 Ternary Photocatalysts for Organic Pollutant Degradation and Production of Hydrogen
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1436–1445
DOI: 10.1021/acssuschemeng.6b02010

Smart Design of Self-Assembled Mesoporous α-FeOOH Nanoparticles: High-Surface-Area Sorbent for Hg2+ from Wastewater
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1272–1279
DOI: 10.1021/acssuschemeng.6b00937

Chemically Modified Cellulose Filter Paper for Heavy Metal Remediation in Water
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1965–1973
DOI: 10.1021/acssuschemeng.6b02768

Nitrogen-Doped Graphene as a Robust Scaffold for the Homogeneous Deposition of Copper Nanostructures: A Nonenzymatic Disposable Glucose Sensor
ACS Sustainable Chem. Eng., 2017, 5 (2), pp 1648–1658
DOI: 10.1021/acssuschemeng.6b02390

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ACS Synthetic Biology

Introducing Our Authors
ACS Synth. Biol., 2017, 6 (2), pp 174–181
DOI: 10.1021/acssynbio.7b00038

Engineering of Taxadiene Synthase for Improved Selectivity and Yield of a Key Taxol Biosynthetic Intermediate
ACS Synth. Biol., 2017, 6 (2), pp 201–205
DOI: 10.1021/acssynbio.6b00206

Controlling Citrate Synthase Expression by CRISPR/Cas9 Genome Editing for n-Butanol Production in Escherichia coli
ACS Synth. Biol., 2017, 6 (2), pp 182–189
DOI: 10.1021/acssynbio.6b00134

Discovery of a Phosphonoacetic Acid Derived Natural Product by Pathway Refactoring
ACS Synth. Biol., 2017, 6 (2), pp 217–223
DOI: 10.1021/acssynbio.6b00299

A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases
ACS Synth. Biol., 2017, 6 (2), pp 326–333
DOI: 10.1021/acssynbio.6b00188

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Analytical Chemistry

Multicolor Gold–Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection
Anal. Chem., 2017, 89 (4), pp 2531–2538
DOI: 10.1021/acs.analchem.6b04729

Separation of Isotopologues in Ultra-High-Resolution Ion Mobility Spectrometry
Open access through ACS Editors’ Choice
Anal. Chem., 2017, 89 (3), pp 1509–1515
DOI: 10.1021/acs.analchem.6b03300

Two-Photon Ratiometric Fluorescence Probe with Enhanced Absorption Cross Section for Imaging and Biosensing of Zinc Ions in Hippocampal Tissue and Zebrafish
Anal. Chem., 2017, 89 (4), pp 2553–2560
DOI: 10.1021/acs.analchem.6b04781

A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells
Anal. Chem., 2017, 89 (3), pp 1801–1807
DOI: 10.1021/acs.analchem.6b04114

Enhanced Photoelectrochemical Method for Sensitive Detection of Protein Kinase A Activity Using TiO2/g-C3N4, PAMAM Dendrimer, and Alkaline Phosphatase
Anal. Chem., 2017, 89 (4), pp 2369–2376
DOI: 10.1021/acs.analchem.6b04184

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Chemical Research in Toxicology

Deep Learning to Predict the Formation of Quinone Species in Drug Metabolism
Chem. Res. Toxicol., 2017, 30 (2), pp 642–656
DOI: 10.1021/acs.chemrestox.6b00385

DNA Advanced Glycation End Products (DNA-AGEs) Are Elevated in Urine and Tissue in an Animal Model of Type 2 Diabetes
Chem. Res. Toxicol., 2017, 30 (2), pp 689–698
DOI: 10.1021/acs.chemrestox.6b00414

Chemical Interaction of Protein Cysteine Residues with Reactive Metabolites of Methyleugenol
Chem. Res. Toxicol., 2017, 30 (2), pp 564–573
DOI: 10.1021/acs.chemrestox.6b00290

Pitfalls and Challenges in Nanotoxicology: A Case of Cobalt Ferrite (CoFe2O4) Nanocomposites
Chem. Res. Toxicol., 2017, 30 (2), pp 492–507
DOI: 10.1021/acs.chemrestox.6b00377

Call for Papers on Mass Spectrometry and Biomarkers in Human Population Studies
Chem. Res. Toxicol., 2017, 30 (2), pp 487–487
DOI: 10.1021/acs.chemrestox.6b00431

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Crystal Growth & Design

Molecular Design of Zirconium Tetrazolate Metal–Organic Frameworks for CO2 Capture
Cryst. Growth Des., 2017, 17 (2), pp 543–549
DOI: 10.1021/acs.cgd.6b01405

Comparative Stability and Sorption Study of Two the-type Metal–Organic Frameworks with Different Multiplicate Metal–Ligand Interactions in Secondary Building Units
Cryst. Growth Des., 2017, 17 (2), pp 418–422
DOI: 10.1021/acs.cgd.6b01716

Nonlinear Optical Rod Indium-Imidazoledicarboxylate Framework as Room-Temperature Gas Sensor for Butanol Isomers
Cryst. Growth Des., 2017, 17 (2), pp 423–427
DOI: 10.1021/acs.cgd.6b01744

Various Polycarboxylate-Directed Cd(II) Coordination Polymers Based on a Semirigid Bis-pyridyl-bis-amide Ligand: Construction and Fluorescent and Photocatalytic Properties
Cryst. Growth Des., 2017, 17 (2), pp 483–496
DOI: 10.1021/acs.cgd.6b01299

Carborane Bis-pyridylalcohols as Linkers for Coordination Polymers: Synthesis, Crystal Structures, and Guest-Framework Dependent Mechanical Properties
Cryst. Growth Des., 2017, 17 (2), pp 846–857
DOI: 10.1021/acs.cgd.6b01682

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Energy & Fuels

Simulation of Asphaltene Aggregation through Molecular Dynamics: Insights and Limitations
Open access through ACS AuthorChoice
Energy Fuels, 2017, 31 (2), pp 1108–1125
DOI: 10.1021/acs.energyfuels.6b02161

Chemical Kinetic Insights into the Octane Number and Octane Sensitivity of Gasoline Surrogate Mixtures
Energy Fuels, 2017, 31 (2), pp 1945–1960
DOI: 10.1021/acs.energyfuels.6b02659

Segregation of Amphiphilic Polymer-Coated Nanoparticles to Bicontinuous Oil/Water Microemulsion Phases
Energy Fuels, 2017, 31 (2), pp 1339–1346
DOI: 10.1021/acs.energyfuels.6b02687

Techno-economic Analysis of Metal–Organic Frameworks for Hydrogen and Natural Gas Storage
Energy Fuels, 2017, 31 (2), pp 2024–2032
DOI: 10.1021/acs.energyfuels.6b02510

New Composite Viscosity Reducer with Both Asphaltene Dispersion and Emulsifying Capability for Heavy and Ultraheavy Crude Oils
Energy Fuels, 2017, 31 (2), pp 1159–1173
DOI: 10.1021/acs.energyfuels.6b02265

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Environmental Science & Technology

Flint Water Crisis Caused By Interrupted Corrosion Control: Investigating “Ground Zero” Home
Open access through ACS AuthorChoice
Environ. Sci. Technol., 2017, 51 (4), pp 2007–2014
DOI: 10.1021/acs.est.6b04034

In Situ Photochemical Activation of Sulfate for Enhanced Degradation of Organic Pollutants in Water
Environ. Sci. Technol., 2017, 51 (4), pp 2339–2346
DOI: 10.1021/acs.est.6b05090

Building a Wall on the Imaginary Line
Environ. Sci. Technol., 2017, 51 (3), pp 1053–1053
DOI: 10.1021/acs.est.6b05220

Burden of Disease from Rising Coal-Fired Power Plant Emissions in Southeast Asia
Open access through ACS AuthorChoice
Environ. Sci. Technol., 2017, 51 (3), pp 1467–1476
DOI: 10.1021/acs.est.6b03731

Continuing the Discussion
Environ. Sci. Technol., 2017, 51 (3), pp 1059–1059
DOI: 10.1021/acs.est.6b06153

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Environmental Science Technology Letters

A pH-Gradient Flow Cell for Converting Waste CO2 into Electricity
Open access through ACS AuthorChoice
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 49–53
DOI: 10.1021/acs.estlett.6b00467

An Inconvenient Administration
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 31–31
DOI: 10.1021/acs.estlett.7b00011

Integrated Framework for Identifying Toxic Transformation Products in Complex Environmental Mixtures
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 32–43
DOI: 10.1021/acs.estlett.6b00455

Lubricating Oil as a Major Constituent of Ship Exhaust Particles
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 54–58
DOI: 10.1021/acs.estlett.6b00488

Identification of Mercury and Dissolved Organic Matter Complexes Using Ultrahigh Resolution Mass Spectrometry
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 59–65
DOI: 10.1021/acs.estlett.6b00460

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Industrial & Engineering Chemistry Research 

Biomimetic Superhydrophobic Engineering Metal Surface with Hierarchical Structure and Tunable Adhesion: Design of Microscale Pattern
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (4), pp 907–919
DOI: 10.1021/acs.iecr.6b03936

An Effective Biocatalytic Reactor–Rotating Packed Bed Applied in Hydrolysis Reactions
Open access through ACS Editors’ Choice
Ind. Eng. Chem. Res., 2017, 56 (5), pp 1349–1353
DOI: 10.1021/acs.iecr.6b03381

Comprehensive Analysis of Sorption Enhanced Steam Methane Reforming in a Variable Volume Membrane Reactor
Ind. Eng. Chem. Res., 2017, 56 (7), pp 1758–1771
DOI: 10.1021/acs.iecr.6b04392

Zeolitic Imidazolate Framework-8 (ZIF-8) Membranes for Kr/Xe Separation
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1682–1686
DOI: 10.1021/acs.iecr.6b04868

Facile Synthesis and Direct Activation of Zirconium Based Metal–Organic Frameworks from Acetone
Ind. Eng. Chem. Res., 2017, 56 (6), pp 1478–1484
DOI: 10.1021/acs.iecr.6b04361

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Journal of Agricultural and Food Chemistry

Development of a QuEChERS-Based Method for the Simultaneous Determination of Acidic Pesticides, Their Esters, and Conjugates Following Alkaline Hydrolysis
J. Agric. Food Chem., 2017, 65 (6), pp 1296–1305
DOI: 10.1021/acs.jafc.6b05407

Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
Open access through ACS Editors’ Choice
J. Agric. Food Chem., 2017, 65 (4), pp 752–758
DOI: 10.1021/acs.jafc.6b04538

Analytical Methods Used in the Quality Control of Honey
J. Agric. Food Chem., 2017, 65 (4), pp 690–703
DOI: 10.1021/acs.jafc.6b04776

A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer’s Disease
J. Agric. Food Chem., 2017, 65 (5), pp 1005–1020
DOI: 10.1021/acs.jafc.6b04398

Chemical and Antioxidant Properties of Betalains
J. Agric. Food Chem., 2017, 65 (4), pp 675–689
DOI: 10.1021/acs.jafc.6b04208

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Journal of Chemical & Engineering Data

The Viscosity and Density of Ionic Liquid + Tetraglyme Mixtures and the Effect of Tetraglyme on CO2 Solubility
J. Chem. Eng. Data, 2017, 62 (2), pp 608–622
DOI: 10.1021/acs.jced.6b00596

Evaluating Characteristic Parameters for Carbon Dioxide in the Sanchez–Lacombe Equation of State
J. Chem. Eng. Data, 2017, 62 (2), pp 585–595
DOI: 10.1021/acs.jced.6b00743

Correction to “Measurement and Correlation of 1,4-Naphthoquinone and of Plumbagin Solubilities in Supercritical Carbon Dioxide”
J. Chem. Eng. Data, 2017, 62 (2), pp 886–887
DOI: 10.1021/acs.jced.7b00025

Thermodynamic Study of Methylene Blue Adsorption on Carbon Nanotubes Using Isothermal Titration Calorimetry: A Simple and Rigorous Approach
J. Chem. Eng. Data, 2017, 62 (2), pp 729–737
DOI: 10.1021/acs.jced.6b00804

Correction to “Liquid–Liquid Equilibria in Aqueous Mixtures of Alkylmethylimidazolium Glutamate with Potassium Carbonate and Some Physicochemical Properties of Aqueous [Cnmim][Glu] (n = 4, 6, 8) Solutions”
J. Chem. Eng. Data, 2017, 62 (2), pp 885–885
DOI: 10.1021/acs.jced.6b00906

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Journal of Chemical Information and Modeling

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine
Open access through ACS AuthorChoice
J. Chem. Inf. Model., 2017, 57 (2), pp 115–121
DOI: 10.1021/acs.jcim.6b00686

Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide
J. Chem. Inf. Model., 2017, 57 (2), pp 190–202
DOI: 10.1021/acs.jcim.6b00443

Binding Pose Flip Explained via Enthalpic and Entropic Contributions
Open access through ACS AuthorChoice
J. Chem. Inf. Model., 2017, 57 (2), pp 345–354
DOI: 10.1021/acs.jcim.6b00483

Creating the New from the Old: Combinatorial Libraries Generation with Machine-Learning-Based Compound Structure Optimization
J. Chem. Inf. Model., 2017, 57 (2), pp 133–147
DOI: 10.1021/acs.jcim.6b00426

pmx Webserver: A User Friendly Interface for Alchemistry
J. Chem. Inf. Model., 2017, 57 (2), pp 109–114
DOI: 10.1021/acs.jcim.6b00498

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Journal of Chemical Theory and Computation

Multireference Perturbation Theory with Cholesky Decomposition for the Density Matrix Renormalization Group
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 451–459
DOI: 10.1021/acs.jctc.6b00778

Quantitative Assessment of Molecular Dynamics Sampling for Flexible Systems
J. Chem. Theory Comput., 2017, 13 (2), pp 400–414
DOI: 10.1021/acs.jctc.6b00823

Systematic Quantum Mechanical Region Determination in QM/MM Simulation
J. Chem. Theory Comput., 2017, 13 (2), pp 563–576
DOI: 10.1021/acs.jctc.6b01049

Modeling Diversity in Structures of Bacterial Outer Membrane Lipids
J. Chem. Theory Comput., 2017, 13 (2), pp 811–824
DOI: 10.1021/acs.jctc.6b00856

A Monte Carlo Resampling Approach for the Calculation of Hybrid Classical and Quantum Free Energies
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (2), pp 415–424
DOI: 10.1021/acs.jctc.6b00506

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Journal of Medicinal Chemistry

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
J. Med. Chem., 2017, 60 (4), pp 1247–1261
DOI: 10.1021/acs.jmedchem.6b01751

Recent Advances in Scaffold Hopping
J. Med. Chem., 2017, 60 (4), pp 1238–1246
DOI: 10.1021/acs.jmedchem.6b01437

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions
J. Med. Chem., 2017, 60 (3), pp 839–885
DOI: 10.1021/acs.jmedchem.6b00788

Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A
J. Med. Chem., 2017, 60 (3), pp 1000–1017
DOI: 10.1021/acs.jmedchem.6b01329

Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker
J. Med. Chem., 2017, 60 (3), pp 1060–1075
DOI: 10.1021/acs.jmedchem.6b01460

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The Journal of Physical Chemistry A

Natural Bond Orbitals and the Nature of the Hydrogen Bond
J. Phys. Chem. A, 2017, 121 (7), pp 1531–1534
DOI: 10.1021/acs.jpca.6b12930

Cluster Model Studies of Anion and Molecular Specificities via Electrospray Ionization Photoelectron Spectroscopy
Open access through ACS Editors’ Choice
J. Phys. Chem. A, 2017, 121 (7), pp 1389–1401
DOI: 10.1021/acs.jpca.6b09784

Why Are Addition Reactions to N2 Thermodynamically Unfavorable?
J. Phys. Chem. A, 2017, 121 (5), pp 1140–1144
DOI: 10.1021/acs.jpca.6b11728

Formation Mechanisms of Naphthalene and Indene: From the Interstellar Medium to Combustion Flames
J. Phys. Chem. A, 2017, 121 (5), pp 901–926
DOI: 10.1021/acs.jpca.6b09735

“Watching” the Dark State in Ultrafast Nonadiabatic Photoisomerization Process of a Light-Driven Molecular Rotary Motor
J. Phys. Chem. A, 2017, 121 (6), pp 1240–1249
DOI: 10.1021/acs.jpca.6b12253

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The Journal of Physical Chemistry B

Editorial – Virtual Issue of JPCB on Biophysics
J. Phys. Chem. B, 2017, 121 (5), pp 913–914
DOI: 10.1021/acs.jpcb.6b12749

Characterization of Nanocellulose Using Small-Angle Neutron, X-ray, and Dynamic Light Scattering Techniques
J. Phys. Chem. B, 2017, 121 (6), pp 1340–1351
DOI: 10.1021/acs.jpcb.6b11425

A Spectroscopic and Molecular Simulation Approach toward the Binding Affinity between Lysozyme and Phenazinium Dyes: An Effect on Protein Conformation
J. Phys. Chem. B, 2017, 121 (7), pp 1475–1484
DOI: 10.1021/acs.jpcb.6b10991

The Levinthal Problem in Amyloid Aggregation: Sampling of a Flat Reaction Space
J. Phys. Chem. B, 2017, 121 (7), pp 1576–1586
DOI: 10.1021/acs.jpcb.7b00253

Coarse-Grained Molecular Simulation of the Hierarchical Self-Assembly of π-Conjugated Optoelectronic Peptides
J. Phys. Chem. B, 2017, 121 (7), pp 1684–1706
DOI: 10.1021/acs.jpcb.6b10165

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The Journal of Physical Chemistry C

Photon Reabsorption in Mixed CsPbCl3:CsPbI3 Perovskite Nanocrystal Films for Light-Emitting Diodes
J. Phys. Chem. C, 2017, 121 (7), pp 3790–3796
DOI: 10.1021/acs.jpcc.6b12828

Light-Induced Degradation of CH3NH3PbI3 Hybrid Perovskite Thin Film
J. Phys. Chem. C, 2017, 121 (7), pp 3904–3910
DOI: 10.1021/acs.jpcc.6b11853

Ag Doping of Organometal Lead Halide Perovskites: Morphology Modification and p-Type Character
J. Phys. Chem. C, 2017, 121 (7), pp 3673–3679
DOI: 10.1021/acs.jpcc.6b09722

Control of Symmetry Breaking Size and Aspect Ratio in Gold Nanorods: Underlying Role of Silver Nitrate
J. Phys. Chem. C, 2017, 121 (6), pp 3549–3559
DOI: 10.1021/acs.jpcc.6b10343

Tunable Structural, Electronic, and Optical Properties of Layered Two-Dimensional C2N and MoS2 van der Waals Heterostructure as Photovoltaic Material
J. Phys. Chem. C, 2017, 121 (6), pp 3654–3660
DOI: 10.1021/acs.jpcc.6b12681

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The Journal of Physical Chemistry Letters

Charge Carrier Trapping at Surface Defects of Perovskite Solar Cell Absorbers: A First-Principles Study
Open access through ACS Editors’ Choice
J. Phys. Chem. Lett., 2017, 8 (4), pp 742–746
DOI: 10.1021/acs.jpclett.7b00055

Cs2InAgCl6: A New Lead-Free Halide Double Perovskite with Direct Band Gap
J. Phys. Chem. Lett., 2017, 8 (4), pp 772–778
DOI: 10.1021/acs.jpclett.6b02682

Spectroscopic Evidences for Strong Hydrogen Bonds with Selenomethionine in Proteins
J. Phys. Chem. Lett., 2017, 8 (4), pp 794–800
DOI: 10.1021/acs.jpclett.6b02931

Electron Transfer from Triplet State of TIPS-Pentacene Generated by Singlet Fission Processes to CH3NH3PbI3 Perovskite
J. Phys. Chem. Lett., 2017, 8 (4), pp 884–888
DOI: 10.1021/acs.jpclett.7b00072

First-Principles Study of Novel Two-Dimensional (C4H9NH3)2PbX4 Perovskites for Solar Cell Absorbers
J. Phys. Chem. Lett., 2017, 8 (4), pp 876–883
DOI: 10.1021/acs.jpclett.7b00003

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Journal of Proteome Research

Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein
J. Proteome Res., 2017, 16 (2), pp 920–932
DOI: 10.1021/acs.jproteome.6b00873

The Cover Letter
J. Proteome Res., 2017, 16 (2), pp 367–367
DOI: 10.1021/acs.jproteome.6b01068

Analysis of Reproducibility of Proteome Coverage and Quantitation Using Isobaric Mass Tags (iTRAQ and TMT)
J. Proteome Res., 2017, 16 (2), pp 384–392
DOI: 10.1021/acs.jproteome.5b01154

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer
J. Proteome Res., 2017, 16 (2), pp 609–618
DOI: 10.1021/acs.jproteome.6b00698

Optimization of Acquisition and Data-Processing Parameters for Improved Proteomic Quantification by Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectrometry
J. Proteome Res., 2017, 16 (2), pp 738–747
DOI: 10.1021/acs.jproteome.6b00767

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Molecular Pharmaceutics

Polymer–Drug Nanoparticles Combine Doxorubicin Carrier and Heparin Bioactivity Functionalities for Primary and Metastatic Cancer Treatment
Mol. Pharmaceutics, 2017, 14 (2), pp 513–522
DOI: 10.1021/acs.molpharmaceut.6b00979

Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract
Mol. Pharmaceutics, 2017, 14 (2), pp 345–358
DOI: 10.1021/acs.molpharmaceut.6b00641

Effect of Particle Size on Drug Loading and Release Kinetics of Gefitinib-Loaded PLGA Microspheres
Mol. Pharmaceutics, 2017, 14 (2), pp 459–467
DOI: 10.1021/acs.molpharmaceut.6b00896

Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
Mol. Pharmaceutics, 2017, 14 (2), pp 523–532
DOI: 10.1021/acs.molpharmaceut.6b01010

Self-Assembly PEGylation Retaining Activity (SPRA) Technology via a Host–Guest Interaction Surpassing Conventional PEGylation Methods of Proteins
Mol. Pharmaceutics, 2017, 14 (2), pp 368–376
DOI: 10.1021/acs.molpharmaceut.6b00678

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Organic Process Research & Development

Some Items of Interest to Process R&D Chemists and Engineers
Org. Process Res. Dev., 2017, 21 (2), pp 142–152
DOI: 10.1021/acs.oprd.7b00027

In Praise of Short Papers for OPR&D
Org. Process Res. Dev., 2017, 21 (2), pp 141–141
DOI: 10.1021/acs.oprd.7b00012

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Org. Process Res. Dev., 2017, 21 (2), pp 153–164
DOI: 10.1021/acs.oprd.7b00014

Process Development of a CRF1 Receptor Antagonist Based on the Selective Chlorination of a Benzimidazolone via Chlorine Migration
Org. Process Res. Dev., 2017, 21 (2), pp 222–230
DOI: 10.1021/acs.oprd.6b00389

Sustainable and Scalable Fe/ppm Pd Nanoparticle Nitro Group Reductions in Water at Room Temperature
Org. Process Res. Dev., 2017, 21 (2), pp 247–252
DOI: 10.1021/acs.oprd.6b00410

Discover the Most-Read Analytical Chemistry Articles of Feb. 2017

What were chemists reading in February of 2017? To find out, we’ve compiled lists of the five most-read chemistry articles that appeared in each analytical chemistry ACS Publications journal in February 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.

Check out other posts in the most-read articles series for this month:

ACS Sensors

Single-Step DNA Detection Assay Monitoring Dual-Color Light Scattering from Individual Metal Nanoparticle Aggregates
Open access through ACS AuthorChoice
ACS Sens., 2017, 2 (2), pp 251–256
DOI: 10.1021/acssensors.6b00737

Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
ACS Sens., 2017, 2 (2), pp 243–250
DOI: 10.1021/acssensors.6b00664

What Are Clinically Relevant Levels of Cellular and Biomolecular Analytes?
ACS Sens., 2017, 2 (2), pp 193–197
DOI: 10.1021/acssensors.6b00691

An Ultrasensitive Plasmonic Nanosensor for Aldehydes
ACS Sens., 2017, 2 (2), pp 263–267
DOI: 10.1021/acssensors.6b00769

Inflection Point of the Localized Surface Plasmon Resonance Peak: A General Method to Improve the Sensitivity
ACS Sens., 2017, 2 (2), pp 235–242
DOI: 10.1021/acssensors.6b00633

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Analytical Chemistry

Multicolor Gold–Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection
Anal. Chem., 2017, 89 (4), pp 2531–2538
DOI: 10.1021/acs.analchem.6b04729

Separation of Isotopologues in Ultra-High-Resolution Ion Mobility Spectrometry
Open access through ACS Editors’ Choice
Anal. Chem., 2017, 89 (3), pp 1509–1515
DOI: 10.1021/acs.analchem.6b03300

Two-Photon Ratiometric Fluorescence Probe with Enhanced Absorption Cross Section for Imaging and Biosensing of Zinc Ions in Hippocampal Tissue and Zebrafish
Anal. Chem., 2017, 89 (4), pp 2553–2560
DOI: 10.1021/acs.analchem.6b04781

A Phenylselenium-Substituted BODIPY Fluorescent Turn-off Probe for Fluorescence Imaging of Hydrogen Sulfide in Living Cells
Anal. Chem., 2017, 89 (3), pp 1801–1807
DOI: 10.1021/acs.analchem.6b04114

Enhanced Photoelectrochemical Method for Sensitive Detection of Protein Kinase A Activity Using TiO2/g-C3N4, PAMAM Dendrimer, and Alkaline Phosphatase
Anal. Chem., 2017, 89 (4), pp 2369–2376
DOI: 10.1021/acs.analchem.6b04184

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Chemical Research in Toxicology

Deep Learning to Predict the Formation of Quinone Species in Drug Metabolism
Chem. Res. Toxicol., 2017, 30 (2), pp 642–656
DOI: 10.1021/acs.chemrestox.6b00385

DNA Advanced Glycation End Products (DNA-AGEs) Are Elevated in Urine and Tissue in an Animal Model of Type 2 Diabetes
Chem. Res. Toxicol., 2017, 30 (2), pp 689–698
DOI: 10.1021/acs.chemrestox.6b00414

Chemical Interaction of Protein Cysteine Residues with Reactive Metabolites of Methyleugenol
Chem. Res. Toxicol., 2017, 30 (2), pp 564–573
DOI: 10.1021/acs.chemrestox.6b00290

Pitfalls and Challenges in Nanotoxicology: A Case of Cobalt Ferrite (CoFe2O4) Nanocomposites
Chem. Res. Toxicol., 2017, 30 (2), pp 492–507
DOI: 10.1021/acs.chemrestox.6b00377

Call for Papers on Mass Spectrometry and Biomarkers in Human Population Studies
Chem. Res. Toxicol., 2017, 30 (2), pp 487–487
DOI: 10.1021/acs.chemrestox.6b00431

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Environmental Science & Technology

Flint Water Crisis Caused By Interrupted Corrosion Control: Investigating “Ground Zero” Home
Open access through ACS AuthorChoice
Environ. Sci. Technol., 2017, 51 (4), pp 2007–2014
DOI: 10.1021/acs.est.6b04034

In Situ Photochemical Activation of Sulfate for Enhanced Degradation of Organic Pollutants in Water
Environ. Sci. Technol., 2017, 51 (4), pp 2339–2346
DOI: 10.1021/acs.est.6b05090

Building a Wall on the Imaginary Line
Environ. Sci. Technol., 2017, 51 (3), pp 1053–1053
DOI: 10.1021/acs.est.6b05220

Burden of Disease from Rising Coal-Fired Power Plant Emissions in Southeast Asia
Open access through ACS AuthorChoice
Environ. Sci. Technol., 2017, 51 (3), pp 1467–1476
DOI: 10.1021/acs.est.6b03731

Continuing the Discussion
Environ. Sci. Technol., 2017, 51 (3), pp 1059–1059
DOI: 10.1021/acs.est.6b06153

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Environmental Science Technology Letters

A pH-Gradient Flow Cell for Converting Waste CO2 into Electricity
Open access through ACS AuthorChoice
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 49–53
DOI: 10.1021/acs.estlett.6b00467

An Inconvenient Administration
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 31–31
DOI: 10.1021/acs.estlett.7b00011

Integrated Framework for Identifying Toxic Transformation Products in Complex Environmental Mixtures
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 32–43
DOI: 10.1021/acs.estlett.6b00455

Lubricating Oil as a Major Constituent of Ship Exhaust Particles
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 54–58
DOI: 10.1021/acs.estlett.6b00488

Identification of Mercury and Dissolved Organic Matter Complexes Using Ultrahigh Resolution Mass Spectrometry
Environ. Sci. Technol. Lett., 2017, 4 (2), pp 59–65
DOI: 10.1021/acs.estlett.6b00460

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Journal of Agricultural and Food Chemistry

Development of a QuEChERS-Based Method for the Simultaneous Determination of Acidic Pesticides, Their Esters, and Conjugates Following Alkaline Hydrolysis
J. Agric. Food Chem., 2017, 65 (6), pp 1296–1305
DOI: 10.1021/acs.jafc.6b05407

Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
Open access through ACS Editors’ Choice
J. Agric. Food Chem., 2017, 65 (4), pp 752–758
DOI: 10.1021/acs.jafc.6b04538

Analytical Methods Used in the Quality Control of Honey
J. Agric. Food Chem., 2017, 65 (4), pp 690–703
DOI: 10.1021/acs.jafc.6b04776

A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer’s Disease
J. Agric. Food Chem., 2017, 65 (5), pp 1005–1020
DOI: 10.1021/acs.jafc.6b04398

Chemical and Antioxidant Properties of Betalains
J. Agric. Food Chem., 2017, 65 (4), pp 675–689
DOI: 10.1021/acs.jafc.6b04208

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Journal of Proteome Research

Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein
J. Proteome Res., 2017, 16 (2), pp 920–932
DOI: 10.1021/acs.jproteome.6b00873

The Cover Letter
J. Proteome Res., 2017, 16 (2), pp 367–367
DOI: 10.1021/acs.jproteome.6b01068

Analysis of Reproducibility of Proteome Coverage and Quantitation Using Isobaric Mass Tags (iTRAQ and TMT)
J. Proteome Res., 2017, 16 (2), pp 384–392
DOI: 10.1021/acs.jproteome.5b01154

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer
J. Proteome Res., 2017, 16 (2), pp 609–618
DOI: 10.1021/acs.jproteome.6b00698

Optimization of Acquisition and Data-Processing Parameters for Improved Proteomic Quantification by Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectrometry
J. Proteome Res., 2017, 16 (2), pp 738–747
DOI: 10.1021/acs.jproteome.6b00767

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Why Big Data Matters to Researchers Now More Than Ever

Research has always meant data, but never quite like this. Modern research produces experimental data not just from in vitro and in vivo studies, but also from simulation-driven in silico work. The ability to interpret, compare, and contrast data sets is essential.

As the amount of scientific data increases, it becomes imperative to determine how to store it, archive it, and make it accessible to other researchers and the general public. This openness can have enormous benefits. For example, in medicinal chemistry, data analysis can aid in decision-making for drug discovery research.

This is motivated by parallel synthesis, the creation of increasingly large and complex analytical and biological data sets associated with each new chemical entity, and the requirement to integrate publicly available information, including patent literature, into the design process. If other researchers can easily access this information, it can speed up the production of future research and avoid duplication.

Managing the data is a complex process, however, and it can require the use of specialized tools. Dealing with large data sets isn’t just about file size. It may also mean being able to keep up with evolving data sets or handling a combination of structured and unstructured data. Researchers also need the means to detect errors hidden in rows and rows of tables. These skills may be outside the traditional training of many scientists. In 2016, however, every researcher needs to have at least some skills as a data scientist.

Using existing data sets makes sense. It can save researchers time and money and, when applied to their own work, can potentially aid in research decision-making. “Potentially” is the keyword here, because data is useless if the research community cannot learn how to effectively harness it. While researchers are great at producing data, they need better data management infrastructure, systems, and training. Organizations also need to find standardized ways of structuring data to allow researchers to use it more efficiently. According to one estimate, 40% of all research and design experiments are duplicated effort brought on by efficient design or a lack of information technology resources.

“Conversion of massive amounts of chemical and biological data into cogent insights is becoming a significant area of opportunity. With ever-advancing sensor capabilities and the expanding power of computers to generate computational data the need to understand massive data sets will drive a lot of scientific endeavors and will offer exciting opportunities to advance the chemical and biological sciences,” says Kenneth Merz, Editor-In-Chief of the Journal of Chemical Information and Modeling.

This optimism is shared by many others including Jonathan Sweedler, Editor-in-Chief of Analytical Chemistry. “This is a golden age of measurement science. From the evolving challenges of environmental monitoring to following the chemical intricacies occurring in our brains that give rise to consciousness, analytical chemistry-related grand challenges are capturing national attention and becoming national research priorities.”

This rise in measurement science extends to all industries. And chemists are at the heart of many of these advancements. “Chemists have been central to these developments and will exploit genetic information in new and unexpected ways going forward. Links between genetic changes and their resultant human diseases increasingly will be understood in molecular terms, and new treatments and preventive strategies will emerge,” says Carolyn Bertozzi, Editor-in-Chief of ACS Central Science.

How can we make it easier for researchers to keep having data-fueled discoveries? One answer is education. Scientists of all types need a solid grounding in data management. They should be able to recognize sources of relevant information, prepare raw data, use statistical tools, extract meaningful information, interpret results, recognize potential problems, and make visualizations to convey their findings. That kind of training is especially essential for reviewers and editors, who need to be able to spot false positives and statistical manipulation to prevent spurious studies from gaining traction.

Scientists have more information than ever at their disposal. But to do any good, they have to know how to use it.

ACS Editors’ Choice: Organic Semiconductors — and More!

This week: Organic semiconductors, low-dimensional-networked perovskite derivatives, emantioselective synthesis of (−)-acetylapoaranotin — and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!
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Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance

Mol. Pharmaceutics, Article ASAP
DOI: 10.1021/acs.molpharmaceut.6b01091
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Low-Dimensional-Networked Metal Halide Perovskites: The Next Big Thing


ACS Energy Lett.
, 2017, 2, pp 889–896
DOI: 10.1021/acsenergylett.6b00705
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Rational Redesign of a Functional Protein Kinase-Substrate Interaction

ACS Chem. Biol., Article ASAP
DOI: 10.1021/acschembio.7b00089
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Enantioselective Synthesis of (−)-Acetylapoaranotin

Org. Lett., Article ASAP
DOI: 10.1021/acs.orglett.7b00418
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Formation of Alkanes by Aerobic Carbon–Carbon Bond Coupling Reactions Catalyzed by a Phosphovanadomolybdic Acid

ACS Catal., 2017, 7, pp 2725–2729
DOI: 10.1021/acscatal.7b00461
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50th Anniversary Perspective: Metal-Catalyzed Living Radical Polymerization: Discovery and Perspective

Macromolecules, Article ASAP
DOI: 10.1021/acs.macromol.6b02711
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Mechanical Properties of Organic Semiconductors for Stretchable, Highly Flexible, and Mechanically Robust Electronics

Chem. Rev., Article ASAP
DOI: 10.1021/acs.chemrev.7b00003
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Love ACS Editors’ Choice? Get a weekly e-mail of the latest ACS Editor’s Choice articles and never miss a breakthrough!

Discover the 2nd Most-Read Paper of 2016

Last year 43,000 authors published chemistry research articles in ACS Publications 50 journals. Each of these papers is important, but some of them attracted larger audiences than others. So who were the most-read authors of chemistry research 2016? The honor of being the authors of the third most-read paper in any ACS journal in 2016 goes to Mya Le Thai, Girija Thesma Chandran, Rajen K. Dutta, Xiaowei Li, and Reginald M. Penner. Check out their paper below:

100k Cycles and Beyond: Extraordinary Cycle Stability for MnO2 Nanowires Imparted by a Gel Electrolyte
ACS Energy Lett., 2016, 1 (1), pp 57–63
DOI: 10.1021/acsenergylett.6b00029

Congratulations to all the distinguished authors!

But that raises an important question: Who is the author of the most-read paper of 2016? We know and we’re excited to reveal the answer at this year’s national meeting in San Francisco as part of a big “Thank you!” to our global community of authors and reviewers. We’ve decided to honor the most-read author of 2016 in a unique way. We’ll be creating a guest generated mosaic in real-time over the course of the meeting. If you’ll be attending the meeting, you can help us reveal the author’s identity. Visit the ACS Publications booth and get involved in three simple steps:

  1. SNAP: Take a selfie
  2. POST & TAG: Upload on Instagram or Twitter and use the hashtag #ACSmosaic and tag “amerchemsociety”
  3. PLACE: At the National Meeting stop by the ACS Publications booth to print your photo and place on a matching cell of our interactive mosaic. Together, we’ll build a billboard-sized work of art created in real time to reveal the face of the most-read author in 2016.

Can’t make it to the meeting? Don’t worry, we’ll also be showcasing the most-read author on ACS Axial later in the week.

Check out the other most-read papers of 2016.