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Remembering Gilbert Stork (1921-2017)

Synthetic organic chemistry pioneer Gilbert Stork is dead at the age of 95. Stork was the former Eugene Higgins Professor of Chemistry Emeritus at Columbia University. He is known for his work in the total synthesis of natural products and his contributions to enamine chemistry.

Gilbert Stork was the author of more than 160 papers in ACS journals over 70 years. He published his final paper in Organic Letters last month. That paper, “Synthetic Study toward Total Synthesis of (±)-Germine: Synthesis of (±)-4-Methylenegermine, ” contains a footnote that shows a glimmer of the personality that endeared him to so many in the chemistry community. “At this point, we realized that we did not have enough material (a few milligrams) to go through the several steps for this conversion” he writes. “One would have to restart the whole synthesis. But I (G.S.) am now 95 years old.”

Gilbert Stork was known for achieving the first stereoselective total synthesis of the antimalarial quinine in 2001, despite the “quasi-universal impression” that quinine was synthesized in 1944. He also developed the Stork enamine alkylation.

“Few people in the field of organic chemistry command such deep and unanimous reverence as Gilbert Stork. His impact on the field of synthesis is hard to overstate.  His research, spanning an incredible eight decades, makes up the very fabric of our field,” said Journal of the American Chemical Society Associate Editor Phil S. Baran. “There is no escaping his influence if you are engaged in synthesis. From hypotheses that shaped how we think about terpene biosynthesis to countless reagents and intermediates used daily, they all bear Stork’s fingerprints. Indeed, much of the basic strategies and tactics used in modern retrosynthetic analysis can be traced to the teachings of Gilbert Stork, such as radical cascade reactions, annulations, and enolate chemistry to the very act of stereospecific synthesis. Although we mourn his passing we are cognizant of the fact that his legacy and spirit are eternal and everlasting with much of his groundbreaking work appearing within the pages of JACS as early as 1945.”

“Stork’s lectures, most often delivered with chalk, were legendary!” states Amos Smith, III, Editor-in-Chief of Organic Letters. “At nearly every turn his deep analytical discussion would evolve to provide “gold nuggets” of wisdom on the synthetic question at hand.”

Gilbert Stork liked to joke about his lab habits. He claimed to make diethylaluminum cyanide while wearing a tuxedo on his birthday. Once he dissolved an expired steak in a bath of nitric and sulfuric acid, only to fret that he was “going to produce a pile of nitroglycerine and blow up the entire building with my steak.”

Gilbert Stork was recognized by the ACS throughout his career, winning such awards the 1957 Award in Pure Chemistry of the American Chemical Society, 1967 ACS Award for Creative Work in Synthetic Organic Chemistry, and 2005 Herbert C. Brown Award.

Exploring the Chemistry of Fear with ACS Chemical Neuroscience

Halloween is upon us; a time of tricks and treats, frights and delights, with haunted houses and scary mazes attracting people young and the old. It’s the time of year when we go out of our way to be scared. But why is the anticipation of being spooked so enjoyable? What chemical reaction makes being scared such a scream? What do researchers know about about the chemistry of fear?

Read these articles from ACS Chemical Neuroscience on the chemistry of fear and stress:

Rethinking 5-HT1A Receptors: Emerging Modes of Inhibitory Feedback of Relevance to Emotion-Related Behavior
ACS Chem. Neurosci., 2013, 4 (1), pp 72–83
DOI: 10.1021/cn3002174

Interoception and Learning: Import to Understanding and Treating Diseases and Psychopathologies
ACS Chem. Neurosci., 2014, 5 (8), pp 624–631
DOI: 10.1021/cn5001028

Social Stress Alters Inhibitory Synaptic Input to Distinct Subpopulations of Raphe Serotonin Neurons
ACS Chem. Neurosci., 2013, 4 (1), pp 200–209
DOI: 10.1021/cn300238j

Chronic Mild Stress-Induced Alterations of Local Protein Synthesis: A Role for Cognitive Impairment
ACS Chem. Neurosci., 2017, 8 (4), pp 817–825
DOI: 10.1021/acschemneuro.6b00392

The Rodent Forced Swim Test Measures Stress-Coping Strategy, Not Depression-like Behavior
ACS Chem. Neurosci., 2017, 8 (5), pp 955–960
DOI: 10.1021/acschemneuro.7b00042

A Rodent Model of Traumatic Stress Induces Lasting Sleep and Quantitative Electroencephalographic Disturbances
ACS Chem. Neurosci., 2015, 6 (3), pp 485–493
DOI: 10.1021/cn500342u

Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256
ACS Chem. Neurosci., 2016, 7 (12), pp 1706–1716
DOI: 10.1021/acschemneuro.6b00230

Want more information on the chemistry of fear?

Dr. Anne Andrews, Associate Editor of ACS Chemical Neuroscience spoke to the Today Show last year about what happens inside your body when you feel afraid.

An episode of the Bytesize Science video series explores the chemistry of fear:

Ever wish you were litterally fearless? This video explores the life of a woman living with this condition:

If that’s not enough, the ACS Reactions YouTube channel has an entire playlist of Halloween-related topics.

Get More Information About the Chemistry of Fear (And Other Emotions) in ACS Chemical Neuroscience

Discover ACS Articles with the Highest Altmetric Attention Scores

In December 2016, we announced our partnership with Altmetric, the alternative metrics platform that provides authors with a single view of the online activity surrounding their scholarly content. Through the partnership with Altmetric, we began to display  Altmetric Attention Scores on all research articles published across our entire portfolio of peer-reviewed research journals.

As a researcher or an ACS author, displaying the Altmetric Attention Score gives you the ability to view a more organized and comprehensive record of an article’s online shares, while concurrently tracking discussions of a research article’s findings and results. Altmetric Attention Scores reflect a variety of sources, including social media, traditional media (both mainstream and science specific), online reference managers, forums, and Wikipedia. The information is aggregated to produce a score that is a qualitative measure of the quality and quantity of attention received by an article.

Discover the research articles with the highest Altmetric Attention Scores from each of our scientific areas of interest and learn the details on how each score is generated:

 

Highest Altmetric Attention Score in Analytical Chemistry

Noninvasive Alcohol Monitoring Using a Wearable Tattoo-Based Iontophoretic-Biosensing System
ACS Sens., 2016, 1 (8), pp 1011–1019
DOI: 10.1021/acssensors.6b00356

Click score for details.

Highest Altmetric Attention Score in Applied Chemistry

Sweetened Swimming Pools and Hot Tubs
Environ. Sci. Technol. Lett., 2017, 4 (4), pp 149–153
DOI: 10.1021/acs.estlett.7b00043

Click score for details.

Highest Altmetric Attention Score in Biological Chemistry

The Essential Medicinal Chemistry of Curcumin
J. Med. Chem., 2017, 60 (5), pp 1620–1637
DOI: 10.1021/acs.jmedchem.6b00975

Click score for details.

Highest Altmetric Attention Score in Materials Science & Engineering

Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules
ACS Nano, 2017, 11 (1), pp 112–125
DOI: 10.1021/acsnano.6b04930

Click score for details.

Highest Altmetric Attention Score in Multidisciplinary Chemistry

Development of a Clinically Viable Heroin Vaccine
J. Am. Chem. Soc., 2017, 139 (25), pp 8601–8611
DOI: 10.1021/jacs.7b03334

Click score for details.

 

Highest Altmetric Attention Score in Organic / Inorganic Chemistry

Synthesis of Anthropomorphic Molecules: The NanoPutians
J. Org. Chem., 2003, 68 (23), pp 8750–8766
DOI: 10.1021/jo0349227

Click score for details.

Highest Altmetric Attention Score in Physical Chemistry

Rebirth of a Dead Belousov–Zhabotinsky Oscillator
J. Phys. Chem. A, 2011, 115 (49), pp 14137–14142
DOI: 10.1021/jp200103s

Click score for details.

Learn more about ACS and Altmetric Attention Scores.

Why Should You Publish Open Access? ACS Editors Explain

Carolyn Bertozzi and Luis Liz-Marzan are both editors of fully open access journals. Bertozzi ACS Editor-in-Chief of ACS Central Science, while Liz-Marzan is a Co-Editor of ACS Omega. Watch as they each talk about why researchers should consider publishing their next paper open access.

Learn more about publishing open access with ACS journals.

Sulfur Dioxide Pollution Tied to Degraded Sperm Quality

Men’s sperm counts have plummeted by up to 60% over the last 40 years in Western countries and by nearly 30% since 2001 in China. Experts lack firm answers regarding the cause of the sperm deficit but suspect that behaviors such as smoking or exposures to hormone-disrupting compounds in plastics or pesticides are to blame. A handful of papers have questioned whether air pollution could also affect semen quality. Now, a new study links sulfur dioxide emitted from burning fossil fuels to depressed sperm count and concentration in Chinese men.

“Infertility is a global public health issue affecting at least 50 million couples worldwide,” says Yuewei Liu, an environmental epidemiologist at Hubei Provincial Center for Disease Control & Prevention. Data suggest that poor semen quality accounts for 90% of male infertility. Impaired semen clearly interferes with conception, but it is also often an indicator of other health problems.

While most research has focused on risky behaviors and commercial chemicals as potential causes, experts have recently suggested that air pollutants might damage sperm quality. However, studies on air pollution and semen quality have been inconsistent due to inaccurate measures of an individual’s exposure to pollutants and insufficient sample sizes.

So Liu and his team decided to study semen samples collected from 1,759 men in Wuhan, China. They had all visited Tongji Hospital from 2013 to 2015 seeking help to conceive a child with their partners. The researchers measured sperm concentration, total sperm, and total motile sperm in each sample, controlling for factors that might affect semen quality such as age and smoking. Then the scientists drew on government data from nine air quality monitoring stations in Wuhan—a transportation hub and manufacturing powerhouse—to estimate exposure to air pollutants such as sulfur dioxide, nitrogen dioxide, carbon monoxide, and ozone. Liu employed a model that analyzed the location of the monitoring stations in relationship to each man’s home to predict individual daily pollutant exposures. Because human sperm develops over 90 days, the researchers calculated pollution exposures for the 90 days prior to semen collection so they could look at key periods of sperm development.

When Liu and the team used a statistical test to rate semen quality against increasing air pollution, they found no impact from NO2, CO or O3. However, for each 10 µg/m3 increase in SO2 exposure during the first stage of sperm development, sperm concentration dropped by 6.5%, total sperm count by 11.3%, and total motile sperm by 13.2%, Liu says. Levels of SO2 during the later stages of sperm development did not appear to impact sperm quality. The annual mean SO2 concentrations in Wuhan during the study period ranged from a high of 33 µg/m3 in 2013 to 18 µg/m3 in 2015. In the U.S., annual mean SO2 concentration was less than 5 µg/m3 in 2013.

“Our results indicate for the first time that SO2 exposure may lower semen quality by affecting the earliest stage of sperm development, 70 to 90 days before ejaculation,” Liu says. He speculates that SO2 could impair sperm by triggering oxidative stress and damage to DNA. “Given the limited evidence from epidemiological and in vivo studies, further studies are needed to confirm the association of NO2, CO and O3 with semen quality,” Liu adds. He recommends caution in generalizing the findings to other populations since the men were all from one city in China.

“Even though the study was limited to one city, this paper adds evidence to the existing literature showing a downward trend in sperm concentration and count with increasing exposure to air pollution,” says Bénédicte Jacquemin, an epidemiologist at the health research institute ISGlobal in Barcelona. The study’s findings are more applicable to countries such as China and India where SO2 pollution is severe, she notes. “Exposure to SO2 might not be the cause of decline in sperm quality in North America and Europe, as regulations have lowered SO2 levels for a couple of decades now.”

This article is reproduced with permission from C&EN (© American Chemical Society). The article was first published on October 25, 2017.

ACS Editors’ Choice: Black Pepper as an Anti-Inflammatory

This week: Black pepper as an anti-inflammatory, predicting cysteine reactivity with machine learning, mass efficiency of alkene syntheses — and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!
***
High Throughput Screening Method for Systematic Surveillance of Drugs of Abuse by Multisegment Injection–Capillary Electrophoresis–Mass Spectrometry

Anal. Chem., Article ASAP
DOI: 10.1021/acs.analchem.7b03590
***
Sequence-Based Prediction of Cysteine Reactivity Using Machine Learning

Biochemistry, Article ASAP
DOI: 10.1021/acs.biochem.7b00897
***
An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice

J. Agric. Food Chem., Article ASAP
DOI: 10.1021/acs.jafc.7b02979
***
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale

ACS Nano, Article ASAP
DOI: 10.1021/acsnano.7b05266
***
Match-Making Reactors to Chemistry: A Continuous Manufacturing-Enabled Sequence to a Key Benzoxazole Pharmaceutical Intermediate

Org. Process Res. Dev., Article ASAP
DOI: 10.1021/acs.oprd.7b00254
***
Mass Efficiency of Alkene Syntheses with Tri- and Tetrasubstituted Double Bonds

ACS Sustainable Chem. Eng., Article ASAP
DOI: 10.1021/acssuschemeng.7b02479
***
Photocatalytic Generation of Nitrenes for Rapid Diaziridination

Org. Lett., Article ASAP
DOI: 10.1021/acs.orglett.7b02844
***
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ACS Editors Elected to National Academy of Medicine

Nano Letters Co-Editor Charles M. Lieber and Journal of the American Chemical Society (JACS) Associate Editor Benjamin F. Cravatt are among the newest members of the National Academy of Medicine (NAM). The health and medical community considers membership in NAM to be one of the field’s top honors. NAM membership recognizes individuals who have demonstrated outstanding professional achievement, commitment to service, and major contributions to the advancement of the medical sciences, health care, and public health.

Lieber is the Mark Hyman Professor of Chemistry, and the School of Engineering and Applied Sciences at Harvard University. He is known for his work in synthesizing a variety of nanoscale materials and devices for application in medicine. He’s also the recipient of the ACS Award in the Chemistry of Materials in 2004, and the 1992 ACS Award in Pure Chemistry.

Cravatt is a Professor and Co-Chair of the Department of Molecular Medicine at The Scripps Research Institute. His research group is interested in understanding the roles that enzymes play in physiological and pathological processes, especially as it pertains to the nervous system and cancer. Cravatt is also an Editorial Advisory Board Member of Biochemistry and ACS Chemical Biology. He is the recipient of the 2004 Eli Lilly Award in Biological Chemistry and the 2017 ACS Chemical Biology Lectureship Award.

Lieber and Cravatt are among the 70 regular members and 10 international members elected during NAM’s annual meeting. NAM rules require that at least one quarter of the organization’s total membership come from outside the health professions. NAM now has 2,127 members, along with 172 international members. NAM membership carries with it a commitment to volunteer service to National Academies activities.

NAM was created in 1970 by the National Academy of Sciences as the Institute of Medicine. NAM, along with the National Academy of Sciences and the National Academy of Engineering, provides independent, objective analysis, and advice to the nation on public policy decisions.

Exploring ChemRxiv and the Value of Preprint Servers with Reddit

On October 17, ACS Publication hosted a Reddit AMA with Darla Henderson and Marshall Brennan. The pair manage ChemRxiv, the first preprint server designed for all chemical disciplines. You may remember Henderson’s AMA from January 2016, where she highlighted the ACS open access program to the r/Science community. Brennan is a new addition to the ACS team, and serves as the Publishing Manager for ChemRxiv. Preprint servers such as ChemRxiv are an important part of the publication process, facilitating discussion and feedback within the greater scientific community. As always, Reddit users had a lot of great questions for our hosts.

Check out some highlights from their conversation ChemRxiv and preprint servers:

/u/nate: The physics ArXiv is quite popular for communicating physics work well before it’s published, do you think this chemistry version will take hold as well? What will that mean for traditional chemistry journals?

Marshall Brennan: Quite right, and we do really think that ChemRxiv will take hold! Not only are we seeing submissions across a diverse set of subject areas (we have 16 categories for folks to choose from when submitting, and we’ve had contributions in 14 of them in the ~7 weeks that submissions have been open), but the groups that we would expect to have more of a loyalty to arXiv (computational, physical) are beginning to gravitate to ChemRxiv because we handle raw data and SI much better — one can upload an .xyz file and have a reader download it (and even view its 3D structure right in the browser) rather than having to reconstruct the coordinates from a PDF, which is an error-prone process which, of course, is currently not a possibility. So yes, I think there’s a lot here for chemists specifically, and we’ve seen a strong enough response that I’m quite confident that it will stick around.

Regarding traditional journals, the peer review process remains as important as ever, so they’re not going away. What ChemRxiv does is let authors discuss and hopefully improve on their papers before peer review. With (ideally) higher quality papers making it to editors, we can expect higher quality publications after peer review, and so it really is a symbiotic relationship!

/u/adenovato: Could you talk a bit about why preprint papers are of value to researchers? What’s driving growth in the preprint industry?

Marshall Brennan: Certainly — the short answer is that rapid dissemination leads to rapid evaluation, and that generally improves the pace and quality of research. Too often the peer review process can prevent ideas from permeating the community for up to a year in some cases (remember that, even at a quick-to-publish journal, many papers are rejected and resubmitted, which adds to total review time). In the current system, grant submissions can be impacted, job prospects for students and postdocs can be complicated, and research efforts can be duplicated (imagine if you had recently embarked on a project, and saw a paper that “scoops” it — it had likely been done for a while by the time it was published in a journal, and so if it had been preprinted you could have seen the nascent project and adjusted your focus, or, even better, reached out to collaborate and perhaps have better outcomes than one would have had on their own. We’ve seen countless examples of this by chemists using arXiv and bioRxiv (off the top of my head, I know Jan Jensen has written about this on his blog at Molecular Modeling Basics), so it isn’t a pipe dream: it actually happens!

/u/dschne: Chad Mirkin stated at a recent ACS conference during a ACS Pubs Q&A session that JACS will not accept papers that have been uploaded to ChemRxiv (or any other preprint service) because this counts as a prior publication. 1) Are you aware of any other ACS Publications that will reject papers that uploaded to ChemRxiv? 2) In your opinion will ACS Pubs change this policy in the future, or is it determined by the head editors of the respective journals?

Darla Henderson: When we started this journey and discussion with the community about a year and a half ago, very few ACS journals allowed preprints to be submitted to the journal. At this time, ca. 80% of ACS journals say yes to preprints – noting that not all policy documents are updated, those are in progress as we speak. JACS, Organic Letters, and Journal of Natural Products currently disallow preprints, and Journal of Chemical Education, Chemical Research in Toxicology are on a case by case type of basis (sometimes yes, other times no). Similarly, Chemical Reviews and Accounts of Chemical Research, currently both review-type journals, do not address preprints in their policies – in practice, there’s been no demand from their market to allow preprints.

The beauty of ACS is that when we say “community driven” we mean “community driven”. New journals are brought on by community demand, the Editor in Chief of each journal is a practicing researcher, a leader in the field who is identified, recruited, and recommended by a community “search” committee to the board of directors, the health of the journal editorially and how it is serving the community is evaluated at least every 5 years by a committee of community members. Editors of ACS journals as the representatives of the communities the journals serve, determine the content that is published in their journals. We respect that practice. We are working alongside all the Editors, teams, and journals to provide information and data about preprints, help identify questions outstanding, and advance those for discussion, and dig in to develop best practices around preprints that allow ChemRxiv to meet every chemistry community’s needs.

Learn more about ACS Science Tuesdays on Reddit and view upcoming AMAs.

ACS Publications’ Darla Henderson Talks About Preprints and the Future of Open Access

The peer review process is an important part of publishing scientific work, but it is not perfect. Work can be rejected by peer-reviewed journals simply because the research isn’t deemed important enough, while important scientific discoveries can be delayed from being announced to the world because of bottlenecks in the peer review process.

Preprint servers are one potential answer to this, and they are growing more important in an increasingly digital world. Preprint servers allow researchers to upload their preliminary findings and share them freely with other scientists before the work has gone through peer review.

Darla Henderson, Assistant Director and Publisher of Open Access Programs at ACS Publications, was recently interviewed on the Digital Science podcast about the role preprints play in chemistry today. Henderson has spent much of her career dealing with the publishing and access of information in the field of chemistry. She has been with ACS since 2008 and currently leads open access initiatives for the society.

Preprint servers are important because they make it easier to share information, Henderson said. Authors put in a great deal of research before they release anything they find, and preprints are part of that process.

“Preprints provide transparency. They show what it is that the author has done on his own and is ready to share. They also speed up the process by allowing the posting and the showing of findings earlier, and hopefully will lead to a more complex picture of the scientific process,” she told host Cameron Shepherd.

Open access journals are another way to show more of the scientific process by allowing the scientific community full access to the completed work. She said this could increase the visibility of the work, and help to increase understanding of science.

Earlier this year, ACS, with initial strategic input from the Royal Society of Chemistry (RSC), the German Chemical Society (GDCh) and other not-for-profit organizations, launched an open access preprint server for the chemistry community called ChemRxiv. It serves as a hub for preliminary work that has not been peer reviewed. ACS manages ChemRxiv on behalf of the chemistry community. ChemRxiv is powered by Figshare, an online digital repository for academic research.

“Our selection of Figshare was based on the fact that we felt that they offered a future solution that would enable scientists to have the broadest tool for communication,” Henderson said. “Figshare allows a large variety of file types to be submitted by the author, to be preserved through the triage process, and then be presented to the user in a viewer and for download of the original files at the end stage.”

The purpose of preprint servers like ChemRxiv is to speed up the researcher’s workflow and facilitate greater communication of findings within the scientific community, she adds.

Learn More About Preprints and ChemRxiv.

10 Amazing Periodic Table of the Elements Designs

The periodic table is a marvel of design. Dmitri Mendeleev’s approach to organizing the elements was informative and elegant. It even helped predict the existence of elements then unknown to scientists. A periodic table is an important tool for scientists, but also for educators. The periodic table is an accessible way to teach students about the elements and their properties. It can also be inspirational. Engaging periodic tables can help pique a student’s interest in chemistry, opening up a variety of science career opportunities.

Scientists have proposed a variety of alternative periodic tables over the years. Yet scientists and educators continue to use the 18-column periodic table model developed by Horace Groves Deming, based on Mendeleev’s work. Even within that framework, however, designers continue to innovate, producing periodic tables that add interesting supplemental information or even just some visual flair. In this post, we’ll look some of the best periodic table designs on the web and all the ways they inform, entertain, and inspire viewers with the transformative power of chemistry. We won’t be looking at alternative periodic tables or “periodic tables” of other objects. Those are both excellent topics, but they’ll have to wait for their own posts.

Check out these amazing periodic table of the elements designs:

IUPAC Periodic Table of the Elements and Isotopes:

Take a closer look at each element with this interactive table from IUPAC. Each square contains a pie chart showing the abundance of the isotopes that make up the element’s atomic weight.

The Periodic Table of Elements & Country of Discovery:

This charming design from Dr. Jamie Gallagher incorporates flags to show the country or countries of origin of the scientists who first isolated each element. The table marks elements isolated before the rise of modern science as “known to the ancients,” so we don’t need to argue over whether ancient Egypt or Mesopotamia discovered iron.

The Periodic Table of the Elephants:

A malapropism turns into a fine work of design in this table, designed by high school students from Patapsco High School and Center for the Arts in in Dundalk, MD for a statue that’s now part of ACS headquarters in Washington DC. This table exchanges most of the scientific information typically found on a periodic table for a lively series of cartoon elephants embodying the properties of various elements.

Interactive Periodic Table of the Elements, in Pictures and Words:

Ever struggle to think of a common use for americium? This design from Keith Enevoldsen shows an example of how most of the elements. Hang this up in a classroom or lab, and you’ll always know we commonly use americium in smoke detectors. Click on each element to learn more about its properties and common uses.

The Periodic Table of Endangered Elements:

An estimated 44 of the 118 elements will be in short supply in the future. This table, designed by Andy Brunning of Compound Interest, illustrates this problem. The table designates which elements are in scarce supply, which ones are increasingly high demand, and which ones could be at serious risk in the next century. The table refers to research from the Chemical Innovation Knowledge Transfer Network.

The Periodic Table of Moles:

If you’ve ever been to an ACS National Meeting & Exhibition, you’ve seen the ACS mole mascots in action. For this table, student members of ACS ChemClubs from all over the United States were asked to design squares for the table, incorporating moles in a variety of ways.

The Periodic Table of Videos:

This is the table for you if you’re an audio-visual learner. Watch a short video on each element with this interactive periodic table from video journalist Brady Haran working with chemists at The University of Nottingham. If you’re interested in making the videos easy to browse on a smartphone, you might consider printing out the QR code version of the table.

The Periodic Table of Samples:

This table, from Theodore Gray, features images of samples of each element. Ultra-scarce human-made elements like Ferium are represented by symbols of the places and pictures of the people for which the element is named. Check out former ACS President Glenn T. Seaborg at 106!

University of Waterloo Artistic Periodic Table:

In celebration of the International Year of Chemistry, a variety of artists, photographers, and designers created the images for this illustrated table from Chem 13 News magazine and the University of Waterloo’s Department of Chemistry.

Printable Periodic Table from ACS:

In November 2016, IUPAC finalized names for the new elements 113, 115, 117, and 118. ACS produced this table with a clean, modern design to ensure every class and lab had access to a printable periodic table with the latest information.

What’s your favorite periodic table design? Share your pick in the comments!