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Discover the Most-Read Physical Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Applied Energy Materials
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Cathodic Hydrogen Peroxide Electrosynthesis Using Anthraquinone Modified Carbon Nitride on Gas Diffusion Electrode
DOI: 10.1021/acsaem.9b01445

Efficient Solar Water Splitting Photocathodes Comprising a Copper Oxide Heterostructure Protected by a Thin Carbon Layer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01290

Hydrophobic Side-Chain Attached Polyarylether-Based Anion Exchange Membranes with Enhanced Alkaline Stability
DOI: 10.1021/acsaem.9b01553

Ag–TiO2 Hybrid Nanocrystal Photocatalyst: Hydrogen Evolution under UV Irradiation but Not under Visible-Light Irradiation
DOI: 10.1021/acsaem.9b01730

Double-Shelled Co3O4/C Nanocages Enabling Polysulfides Adsorption for High-Performance Lithium–Sulfur Batteries
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01621


ACS Earth and Space Chemistry

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Iron Redox Chemistry and Its Environmental Impact: A Virtual Special Issue
DOI: 10.1021/acsearthspacechem.9b00282

Virtual Issue on Astrochemistry: From the Chemical Laboratory to the Stars
DOI: 10.1021/acsearthspacechem.9b00259

A High-Pressure Compound of Argon and Nickel: Noble Gas in the Earth’s Core?
DOI: 10.1021/acsearthspacechem.9b00212

Enhanced Immobilization of Arsenic from Acid Mine Drainage by Detrital Clay Minerals
DOI: 10.1021/acsearthspacechem.9b00203

Layer Charge Effects on Adsorption and Diffusion of Water and Ions in Interlayers and on External Surfaces of Montmorillonite
DOI: 10.1021/acsearthspacechem.9b00236


ACS Energy Letters

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2019 Nobel Prize for the Li-Ion Batteries and New Opportunities and Challenges in Na-Ion Batteries
DOI: 10.1021/acsenergylett.9b02190

Lithium-Ion Batteries and Beyond: Celebrating the 2019 Nobel Prize in Chemistry – A Virtual Issue
DOI: 10.1021/acsenergylett.9b02280

Direct Synthesis of Quaternary Alkylammonium-Capped Perovskite Nanocrystals for Efficient Blue and Green Light-Emitting Diodes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsenergylett.9b01915

Industrial Insights into Perovskite Photovoltaics
DOI: 10.1021/acsenergylett.9b02105

New Insight on the Role of Electrolyte Additives in Rechargeable Lithium Ion Batteries
DOI: 10.1021/acsenergylett.9b01441


ACS Photonics

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Multicolor High-Speed Tracking of Single Biomolecules with Silver, Gold, and Silver–Gold Alloy Nanoparticles
DOI: 10.1021/acsphotonics.9b00953

Converting an Organic Light-Emitting Diode from Blue to White with Bragg Modes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsphotonics.9b01206

Electrically Biased Silicon Metasurfaces with Magnetic Mie Resonance for Tunable Harmonic Generation of Light
DOI: 10.1021/acsphotonics.9b01398

Enhanced Fields in Mirror-Backed Low-Index Dielectric Structures
DOI: 10.1021/acsphotonics.9b00931

Reduced Density-Matrix Approach to Strong Matter-Photon Interaction
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsphotonics.9b00648


Energy & Fuels

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Evolution of Aromatic Structures during the Low-Temperature Electrochemical Upgrading of Bio-oil
DOI: 10.1021/acs.energyfuels.9b03099

NMR Spectroscopy Analysis of Asphaltenes
DOI: 10.1021/acs.energyfuels.9b02240

Biocrude Production from Fast and Isothermal Hydrothermal Liquefaction of Chitin
DOI: 10.1021/acs.energyfuels.9b03209

Adsorption of Methane, Nitrogen, and Carbon Dioxide in Atomic-Scale Fractal Nanopores by Monte Carlo Simulation I: Single-Component Adsorption
DOI: 10.1021/acs.energyfuels.9b01405

Alcohol-Assisted Waterflooding in Carbonate Reservoirs
DOI: 10.1021/acs.energyfuels.9b02497


Industrial & Engineering Chemistry Research

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Preface to the Mohamed El-Aasser Festschrift
DOI: 10.1021/acs.iecr.9b05839

An Airlift Crystallizer for Protein Crystallization
DOI: 10.1021/acs.iecr.9b03535

Superelastic and Durable Hierarchical Porous Thermoplastic Polyurethane Monolith with Excellent Hydrophobicity for Highly Efficient Oil/Water Separation
DOI: 10.1021/acs.iecr.9b03717

Advanced Amino Acid-Based Technologies for CO2 Capture: A Review
DOI: 10.1021/acs.iecr.9b01793

Predicting Metal–Support Interactions in Oxide-Supported Single-Atom Catalysts
DOI: 10.1021/acs.iecr.9b04068


Journal of Chemical & Engineering Data

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Celebrating JCED’s High Impact Authors
DOI: 10.1021/acs.jced.9b01050

Taking Another Look at the van der Waals Equation of State–Almost 150 Years Later
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jced.9b00264

Liquid Properties of Ionic Liquids Based on Phosphonium Cations with (Alkylthio)alkyl Groups
DOI: 10.1021/acs.jced.9b00033

Peroxidase Mimic Activity of Au–Ag/l-Cys-rGO Nanozyme toward Detection of Cr(VI) Ion in Water: Role of 3,3′,5,5′-Tetramethylbenzidine Adsorption
DOI: 10.1021/acs.jced.9b00819

Solubility and Diffusivity of Oxygen in Ionic Liquids
DOI: 10.1021/acs.jced.9b00750


Journal of Chemical Information and Modeling

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Designing DNA Encoded Libraries of Diverse Products in a Focused Property Space
DOI: 10.1021/acs.jcim.9b00729

Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters
DOI: 10.1021/acs.jcim.9b00460

Deep Transferable Compound Representation across Domains and Tasks for Low Data Drug Discovery
DOI: 10.1021/acs.jcim.9b00626

Incorporating Explicit Water Molecules and Ligand Conformation Stability in Machine-Learning Scoring Functions
DOI: 10.1021/acs.jcim.9b00645

AntiBac-Pred: A Web Application for Predicting Antibacterial Activity of Chemical Compounds
DOI: 10.1021/acs.jcim.9b00436


Journal of Chemical Theory and Computation

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OpenMolcas: From Source Code to Insight
DOI: 10.1021/acs.jctc.9b00532

HFLD: A Nonempirical London Dispersion-Corrected Hartree–Fock Method for the Quantification and Analysis of Noncovalent Interaction Energies of Large Molecular Systems
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00425

String Method for Protein–Protein Binding Free-Energy Calculations
DOI: 10.1021/acs.jctc.9b00499

Less Is More: Coarse-Grained Integrative Modeling of Large Biomolecular Assemblies with HADDOCK
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00310

MemSurfer: A Tool for Robust Computation and Characterization of Curved Membranes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00453


The Journal of Physical Chemistry A

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Virtual Issue on Astrochemistry: From the Chemical Laboratory to the Stars
DOI: 10.1021/acs.jpca.9b09582

Gaussian Process Regression for Minimum Energy Path Optimization and Transition State Search
DOI: 10.1021/acs.jpca.9b08239

Improving Performance of the SMD Solvation Model: Bondi Radii Improve Predicted Aqueous Solvation Free Energies of Ions and pKa Values of Thiols
DOI: 10.1021/acs.jpca.9b02340

Kinetic Study of the Temperature Dependence of OH-Initiated Oxidation of n-Dodecane
DOI: 10.1021/acs.jpca.9b07704

Electronic Communication as a Transferable Property of Molecular Bridges?
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpca.9b05618


The Journal of Physical Chemistry B

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Energy Transport across Interfaces in Biomolecular Systems
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07086

Halogen Bonding beyond Crystals in Materials Science
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07035

Solubility of Caffeine in Supercritical CO2: A Molecular Dynamics Simulation Study
DOI: 10.1021/acs.jpcb.9b08351

Hydrogen Abstraction of Ketoprofen in the Excited Triplet State with Indole and Methylindoles
DOI: 10.1021/acs.jpcb.9b06786

Interaction and Dynamics in a Fully Biodegradable Glucose-Containing Naturally Abundant Deep Eutectic Solvent: Temperature-Dependent Time-Resolved Fluorescence Measurements
DOI: 10.1021/acs.jpcb.9b06783


The Journal of Physical Chemistry C

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Getting the Right Twist: Influence of Donor–Acceptor Dihedral Angle on Exciton Kinetics and Singlet–Triplet Gap in Deep Blue Thermally Activated Delayed Fluorescence Emitter
DOI: 10.1021/acs.jpcc.9b08269

Film Conformality and Extracted Recombination Probabilities of O Atoms during Plasma-Assisted Atomic Layer Deposition of SiO2, TiO2, Al2O3, and HfO2
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b08176

Theory of Impedance Spectroscopy for Lithium Batteries
DOI: 10.1021/acs.jpcc.9b07389

Charge Transfer during the Dissociation of H2 and the Charge State of H Atoms in Liquid Gallium
DOI: 10.1021/acs.jpcc.9b06779

Transmission Line Model for Description of the Impedance Response of Li Electrodes with Dendritic Growth
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b05887


The Journal of Physical Chemistry Letters

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Singlet Fission in Crystalline Organic Materials: Recent Insights and Future Directions
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpclett.9b00754

Two-Dimensional Ferroics and Multiferroics: Platforms for New Physics and Applications
DOI: 10.1021/acs.jpclett.9b01969

Ultrafast Tracking of Exciton and Charge Carrier Transport in Optoelectronic Materials on the Nanometer Scale
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpclett.9b02437

Carrier Extraction from Perovskite to Polymeric Charge Transport Layers Probed by Ultrafast Transient Absorption Spectroscopy
DOI: 10.1021/acs.jpclett.9b02502

CsPbBr3 Perovskite Nanocrystal Grown on MXene Nanosheets for Enhanced Photoelectric Detection and Photocatalytic CO2 Reduction
DOI: 10.1021/acs.jpclett.9b02605


Discover the Most-Read Organic/Inorganic Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Catalysis

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Operando Insights into Nanoparticle Transformations during Catalysis
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscatal.9b01831

Recent Insights into the Oxygen-Reduction Electrocatalysis of Fe/N/C Materials
DOI: 10.1021/acscatal.9b02583

Copper Single Atoms Anchored in Porous Nitrogen-Doped Carbon as Efficient pH-Universal Catalysts for the Nitrogen Reduction Reaction
DOI: 10.1021/acscatal.9b02944

Site-Selective C–H Acylation of Pyridinium Derivatives by Photoredox Catalysis
DOI: 10.1021/acscatal.9b03367

Recent Advances and Prospective in Ruthenium-Based Materials for Electrochemical Water Splitting
DOI: 10.1021/acscatal.9b02457


ACS Combinatorial Science

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Calculating Resin Functionalization in Solid-Phase Peptide Synthesis Using a Standardized Method based on Fmoc Determination
DOI: 10.1021/acscombsci.9b00154

Cleaning Matters!
DOI: 10.1021/acscombsci.9b00122

Metric Learning for High-Throughput Combinatorial Data Sets
DOI: 10.1021/acscombsci.9b00086

Profiling Protein Tyrosine Phosphatase Specificity with Self-Assembled Monolayers for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Peptide Arrays
DOI: 10.1021/acscombsci.9b00152

Alloyed Thermoelectric PbTe–SnTe Films Formed via Aerosol Deposition
DOI: 10.1021/acscombsci.9b00145


ACS Medicinal Chemistry Letters

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Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
DOI: 10.1021/acsmedchemlett.9b00381

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
DOI: 10.1021/acsmedchemlett.9b00141

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
DOI: 10.1021/acsmedchemlett.9b00377

Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation
DOI: 10.1021/acsmedchemlett.9b00409

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy
DOI: 10.1021/acsmedchemlett.9b00344


Bioconjugate Chemistry

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Going Native: Synthesis of Glycoproteins and Glycopeptides via Native Linkages To Study Glycan-Specific Roles in the Immune System
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00588

Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy
DOI: 10.1021/acs.bioconjchem.9b00564

Hydrophilic Sequence-Defined Cross-Linkers for Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00713

Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00609

Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00548


Inorganic Chemistry

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Supramolecular Anchoring of Octahedral Molybdenum Clusters onto Graphene and Their Synergies in Photocatalytic Water Reduction
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.inorgchem.9b02529

Viewpoint: Atomic-Scale Design Protocols toward Energy, Electronic, Catalysis, and Sensing Applications
DOI: 10.1021/acs.inorgchem.9b01785

Terbium Triangle Bridged by a Triazole Nitronyl Nitroxide Radical with Single-Molecule-Magnet Behavior
DOI: 10.1021/acs.inorgchem.9b01647

Electronic Structure of Tetracyanonickelate(II)
DOI: 10.1021/acs.inorgchem.9b02135

Redox Tuning via Ligand-Induced Geometric Distortions at a YMn3O4 Cubane Model of the Biological Oxygen Evolving Complex
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.inorgchem.9b00510


Journal of Medicinal Chemistry

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How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining
DOI: 10.1021/acs.jmedchem.9b01545

Overview of Recent Strategic Advances in Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b00359

Halogens in Protein–Ligand Binding Mechanism: A Structural Perspective
DOI: 10.1021/acs.jmedchem.8b01453

The Blood–Brain Barrier (BBB) Score
DOI: 10.1021/acs.jmedchem.9b01220

Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
DOI: 10.1021/acs.jmedchem.9b00846


Journal of Natural Products

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Ealamines A–H, a Series of Naphthylisoquinolines with the Rare 7,8′-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jnatprod.9b00755

Terpenoids from the Stems of Fissistigma polyanthoides and Their Anti-Inflammatory Activity
DOI: 10.1021/acs.jnatprod.9b00208

Total Synthesis of Clavatadine B
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jnatprod.9b00813

Anti-inflammatory and α-Glucosidase Inhibitory Activities of Labdane and Norlabdane Diterpenoids from the Rhizomes of Amomum villosum
DOI: 10.1021/acs.jnatprod.9b00283

Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
DOI: 10.1021/acs.jnatprod.8b00380


The Journal of Organic Chemistry

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Recent Advances in Titanium Radical Redox Catalysis
DOI: 10.1021/acs.joc.9b02465

Technical Synthesis of 1,5,9-Cyclododecatriene Revisited: Surprising Byproducts from a Venerable Industrial Process
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.joc.9b01633

Asymmetric Total Synthesis of (+)-Winchinine B
DOI: 10.1021/acs.joc.9b02462

Total Synthesis of (−)-Phomoarcherin C
DOI: 10.1021/acs.joc.9b02206

Direct Amidation of Carboxylic Acids with Nitroarenes
DOI: 10.1021/acs.joc.9b02068


Molecular Pharmaceutics

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A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies
DOI: 10.1021/acs.molpharmaceut.9b00519

Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
DOI: 10.1021/acs.molpharmaceut.9b00361

Molecular Engineering of Adeno-Associated Virus Capsid Improves Its Therapeutic Gene Transfer in Murine Models of Hemophilia and Retinal Degeneration
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00959

Bioconjugation of Cyclometalated Gold(III) Lipoic Acid Fragments to Linear and Cyclic Breast Cancer Targeting Peptides
DOI: 10.1021/acs.molpharmaceut.9b00695

Deep Convolutional Generative Adversarial Network (dcGAN) Models for Screening and Design of Small Molecules Targeting Cannabinoid Receptors
DOI: 10.1021/acs.molpharmaceut.9b00500


Organic Letters

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Letters from India: A Personal Perspective from the Subcontinent
DOI: 10.1021/acs.orglett.9b03837

Alkaline-Metal-Catalyzed One-Pot Aminobenzylation of Aldehydes with Toluenes
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.orglett.9b02737

N-Alkylation-Initiated Redox-Neutral [5 + 2] Annulation of 3-Alkylindoles with o-Aminobenzaldehydes: Access to Indole-1,2-Fused 1,4-Benzodiazepines
DOI: 10.1021/acs.orglett.9b03011

Asymmetric Synthesis of γ-Amino Alcohols by Copper-Catalyzed Hydroamination
DOI: 10.1021/acs.orglett.9b03356

Synthesis of (+)-Tacamonine via Stereoselective Radical Cyclization
DOI: 10.1021/acs.orglett.9b03308


Organic Process Research & Development

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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.9b00465

Green Chemistry Articles of Interest to the Pharmaceutical Industry
DOI: 10.1021/acs.oprd.9b00450

Mutagenic Impurities in 1-Hydroxybenzotriazole (HOBt)
DOI: 10.1021/acs.oprd.9b00376

Scalable, Economical, and Practical Synthesis of 4-(Difluoromethyl)pyridin-2-amine, a Key Intermediate for Lipid Kinase Inhibitors
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.oprd.9b00312

A Scalable Process for the Synthesis of 1,2-Dialkyldiselanes and 1-Alkaneselenols
DOI: 10.1021/acs.oprd.9b00380


Organometallics

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An Information-Rich Graphical Representation of Catalytic Cycles
DOI: 10.1021/acs.organomet.9b00563

Masked Radicals: Iron Complexes of Trityl, Benzophenone, and Phenylacetylene
DOI: 10.1021/acs.organomet.9b00534

Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.organomet.9b00327

Structure and Dynamics of Iron Pentacarbonyl
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.organomet.9b00559

Cooperative CO2 Scission by Anomalous Insertion into a Rh–Si Bond
DOI: 10.1021/acs.organomet.9b00556


Discover the Most-Read Multidisciplinary Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


Accounts of Chemical Research

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Chemical Nanoplasmonics: Emerging Interdisciplinary Research Field at Crossroads between Nanoscale Chemistry and Plasmonics
This article is part of the Nanochemistry for Plasmonics and Plasmonics for Nanochemistry special issue.
DOI: 10.1021/acs.accounts.9b00504

Artificial Photosynthesis at Efficiencies Greatly Exceeding That of Natural Photosynthesis
DOI: 10.1021/acs.accounts.9b00380

The Chemistry of Boronic Acids in Nanomaterials for Drug Delivery
DOI: 10.1021/acs.accounts.9b00292

Hydrogels as an Emerging Material Platform for Solar Water Purification
DOI: 10.1021/acs.accounts.9b00455

Charge-Carrier Dynamics of Lead-Free Halide Perovskite Nanocrystals
DOI: 10.1021/acs.accounts.9b00422


ACS Central Science

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The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscentsci.9b00806

Upcycling Single-Use Polyethylene into High-Quality Liquid Products
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscentsci.9b00722

Stretchable and Fully Degradable Semiconductors for Transient Electronics
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscentsci.9b00850

A Conversation with Melissa Denecke
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscentsci.9b01155

Chemical Control over Nucleation and Anisotropic Growth of Two-Dimensional Covalent Organic Frameworks
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscentsci.9b00944


ACS Omega

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Two-Dimensional Covalent Organic Framework–Graphene Photodetectors: Insight into the Relationship between the Microscopic Interfacial Structure and Performance
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsomega.9b02739

All-Dielectric Terahertz Plasmonic Metamaterial Absorbers and High-Sensitivity Sensing
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsomega.9b02506

Mysterious SiB3: Identifying the Relation between α- and β-SiB3
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsomega.9b02727

Synthesis and Spectral Properties of 8-Anilinonaphthalene-1-sulfonic Acid (ANS) Derivatives Prepared by Microwave-Assisted Copper(0)-Catalyzed Ullmann Reaction
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsomega.9b03002

Tailored Engineering of Bimetallic Plasmonic Au@Ag Core@Shell Nanoparticles
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsomega.9b01897


Chemical Reviews

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Do Diradicals Behave Like Radicals?
DOI: 10.1021/acs.chemrev.9b00260

Disease Detection with Molecular Biomarkers: From Chemistry of Body Fluids to Nature-Inspired Chemical Sensors
DOI: 10.1021/acs.chemrev.9b00437

Conotoxins: Chemistry and Biology
DOI: 10.1021/acs.chemrev.9b00207

Small Molecule as Fluorescent Probes for Monitoring Intracellular Enzymatic Transformations
DOI: 10.1021/acs.chemrev.9b00379

Correction to Coumarin-Based Small-Molecule Fluorescent Chemosensors
DOI: 10.1021/acs.chemrev.9b00640


Journal of the American Chemical Society

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Synthesis of Benzylic Alcohols by C–H Oxidation
Open Access Through ACS AuthorChoice
DOI: 10.1021/jacs.9b09496

Direct Synthesis of Cycloalkanes from Diols and Secondary Alcohols or Ketones Using a Homogeneous Manganese Catalyst
Open Access Through ACS AuthorChoice
DOI: 10.1021/jacs.9b08832

Unified Approach to the Chemoselective α-Functionalization of Amides with Heteroatom Nucleophiles
Open Access Through ACS AuthorChoice
DOI: 10.1021/jacs.9b06956

Size-Controllable Synthesis of Uniform Spherical Covalent Organic Frameworks at Room Temperature for Highly Efficient and Selective Enrichment of Hydrophobic Peptides
DOI: 10.1021/jacs.9b09189

Constructing Robust Covalent Organic Frameworks via Multicomponent Reactions
DOI: 10.1021/jacs.9b10625


Journal of Chemical Education

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Introduction to Electron Transfer: Theoretical Foundations and Pedagogical Examples
DOI: 10.1021/acs.jchemed.9b00489

Reproducibility, Replication, and Generalization in Research about Teaching Innovation
DOI: 10.1021/acs.jchemed.9b00982

Connecting Organic Chemistry Concepts with Real-World Contexts by Creating Infographics
DOI: 10.1021/acs.jchemed.9b00605

Representation of Three-Center–Two-Electron Bonds in Covalent Molecules with Bridging Hydrogen Atoms
DOI: 10.1021/acs.jchemed.9b00750

Teaching Enzyme Catalysis Using Interactive Molecular Dynamics in Virtual Reality
DOI: 10.1021/acs.jchemed.9b00181

 


Discover the Most-Read Materials & Engineering Sciences Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Applied Materials & Interfaces
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Plastic-like Hydrogels with Reversible Conversion of Elasticity and Plasticity and Tunable Mechanical Properties
DOI: 10.1021/acsami.9b14158

Transparent, Antifreezing, Ionic Conductive Cellulose Hydrogel with Stable Sensitivity at Subzero Temperature
DOI: 10.1021/acsami.9b15849

Highly Compressible and Robust Polyimide/Carbon Nanotube Composite Aerogel for High-Performance Wearable Pressure Sensor
DOI: 10.1021/acsami.9b14688

Boosting the Photocatalytic Ability of g-C3N4 for Hydrogen Production by Ti3C2 MXene Quantum Dots
DOI: 10.1021/acsami.9b14985

Engineering of Nitrogen Coordinated Single Cobalt Atom Moieties for Oxygen Electroreduction
DOI: 10.1021/acsami.9b11830


ACS Applied Bio Materials

***

Doxorubicin–Metal Coordinated Micellar Nanoparticles for Intracellular Codelivery and Chemo/Chemodynamic Therapy in Vitro
DOI: 10.1021/acsabm.9b00879

Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy
DOI: 10.1021/acsabm.9b00763

Stabilization of Fibronectin by Random Copolymer Brushes Inhibits Macrophage Activation
DOI: 10.1021/acsabm.9b00815

NIR-Triggered Theranostic Bi2S3 Light Transducer for On-Demand NO Release and Synergistic Gas/Photothermal Combination Therapy of Tumors
DOI: 10.1021/acsabm.9b00522

Engineering Human-Scale Artificial Bone Grafts for Treating Critical-Size Bone Defects
DOI: 10.1021/acsabm.9b00756


ACS Applied Electronic Materials

***

Carbonized Chinese Art Paper-Based High-Performance Wearable Strain Sensor for Human Activity Monitoring
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsaelm.9b00564

Performance Improvement of Multilayered SnS2 Field Effect Transistors through Synergistic Effect of Vacancy Repairing and Electron Doping Introduced by EDTA
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsaelm.9b00550

Film-Nanostructure-Controlled Inerasable-to-Erasable Switching Transition in ZnO-Based Transparent Memristor Devices: Sputtering-Pressure Dependency
DOI: 10.1021/acsaelm.9b00617

Non-Rare-Earth Na3AlF6:Cr3+ Phosphors for Far-Red Light-Emitting Diodes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaelm.9b00527

Great Differences between Low-Temperature Grown Co2FeSi and Co2MnSi Films on Single-Crystalline Oxides
DOI: 10.1021/acsaelm.9b00546


ACS Applied Energy Materials

***

Cathodic Hydrogen Peroxide Electrosynthesis Using Anthraquinone Modified Carbon Nitride on Gas Diffusion Electrode
DOI: 10.1021/acsaem.9b01445

Efficient Solar Water Splitting Photocathodes Comprising a Copper Oxide Heterostructure Protected by a Thin Carbon Layer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01290

Hydrophobic Side-Chain Attached Polyarylether-Based Anion Exchange Membranes with Enhanced Alkaline Stability
DOI: 10.1021/acsaem.9b01553

Ag–TiO2 Hybrid Nanocrystal Photocatalyst: Hydrogen Evolution under UV Irradiation but Not under Visible-Light Irradiation
DOI: 10.1021/acsaem.9b01730

Double-Shelled Co3O4/C Nanocages Enabling Polysulfides Adsorption for High-Performance Lithium–Sulfur Batteries
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01621


ACS Applied Nano Materials

***

Carboxyl-Functionalized Covalent Organic Frameworks for the Adsorption and Removal of Triphenylmethane Dyes
DOI: 10.1021/acsanm.9b01781

TiO2 Nanofilms on Polymeric Substrates for the Photocatalytic Degradation of Methylene Blue
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsanm.9b01723

Solid-Phase Epitaxy of Perovskite High Dielectric PrAlO3 Films Grown by Atomic Layer Deposition for Use in Two-Dimensional Electronics and Memory Devices
DOI: 10.1021/acsanm.9b02153

Plasmonic Nanocavity Metasurface Based on Laser-Structured Silver Surface and Silver Nanoprisms for the Enhancement of Adenosine Nucleotide Photoluminescence
DOI: 10.1021/acsanm.9b01673

Graphene Nanofluids as Thermal Management Materials: Molecular Dynamics Study on Orientation and Temperature Effects
DOI: 10.1021/acsanm.9b01266


ACS Applied Polymer Materials

***

Degradable Thermoset Fibers from Carbohydrate-Derived Diols via Thiol–Ene Photopolymerization
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsapm.9b00647

Damage-Reporting Carbon Fiber Epoxy Composites
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsapm.9b00694

Luminescent Solar Concentrators Based on Energy Transfer from an Aggregation-Induced Emitter Conjugated Polymer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsapm.9b00718

Mussel-Inspired Tough Double Network Hydrogel As Transparent Adhesive
DOI: 10.1021/acsapm.9b00698

Microfluidic Channels Fabrication Based on Underwater Superpolymphobic Microgrooves Produced by Femtosecond Laser Direct Writing
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsapm.9b00269


ACS Biomaterials Science & Engineering

***

Interfacial Diffusion Printing: An Efficient Manufacturing Technique for Artificial Tubular Grafts
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsbiomaterials.9b01293

Metal–Organic Framework-Integrated Enzymes as Bioreactor for Enhanced Therapy against Solid Tumor via a Cascade Catalytic Reaction
DOI: 10.1021/acsbiomaterials.9b01200

Modular Assembly of Biomaterials Using Polyphenols as Building Blocks
DOI: 10.1021/acsbiomaterials.8b01507

Submicron Patterns-on-a-Chip: Fabrication of a Microfluidic Device Incorporating 3D Printed Surface Ornaments
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.9b01155

3,4-Dihydroxyphenylalanine (DOPA)-Containing Silk Fibroin: Its Enzymatic Synthesis and Adhesion Properties
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.8b01309


ACS Catalysis

***

Operando Insights into Nanoparticle Transformations during Catalysis
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscatal.9b01831

Recent Insights into the Oxygen-Reduction Electrocatalysis of Fe/N/C Materials
DOI: 10.1021/acscatal.9b02583

Copper Single Atoms Anchored in Porous Nitrogen-Doped Carbon as Efficient pH-Universal Catalysts for the Nitrogen Reduction Reaction
DOI: 10.1021/acscatal.9b02944

Site-Selective C–H Acylation of Pyridinium Derivatives by Photoredox Catalysis
DOI: 10.1021/acscatal.9b03367

Recent Advances and Prospective in Ruthenium-Based Materials for Electrochemical Water Splitting
DOI: 10.1021/acscatal.9b02457


ACS Energy Letters

***

2019 Nobel Prize for the Li-Ion Batteries and New Opportunities and Challenges in Na-Ion Batteries
DOI: 10.1021/acsenergylett.9b02190

Lithium-Ion Batteries and Beyond: Celebrating the 2019 Nobel Prize in Chemistry – A Virtual Issue
DOI: 10.1021/acsenergylett.9b02280

Direct Synthesis of Quaternary Alkylammonium-Capped Perovskite Nanocrystals for Efficient Blue and Green Light-Emitting Diodes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsenergylett.9b01915

Industrial Insights into Perovskite Photovoltaics
DOI: 10.1021/acsenergylett.9b02105

New Insight on the Role of Electrolyte Additives in Rechargeable Lithium Ion Batteries
DOI: 10.1021/acsenergylett.9b01441


ACS Macro Letters

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Self-Healing Polyurethane Elastomers Based on a Disulfide Bond by Digital Light Processing 3D Printing
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsmacrolett.9b00766

Toughening of Glassy Supramolecular Polymer Networks
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsmacrolett.9b00710

Tough Double-Network Gels and Elastomers from the Nonprestretched First Network
DOI: 10.1021/acsmacrolett.9b00679

Liquid Metal Nanoparticles as Initiators for Radical Polymerization of Vinyl Monomers
DOI: 10.1021/acsmacrolett.9b00783

Gelation Mechanism and Structural Dynamics of Chitosan Self-Healing Hydrogels by In Situ SAXS and Coherent X-ray Scattering
DOI: 10.1021/acsmacrolett.9b00683


ACS Nano

***

San Sebastian, a City of (Nano)Science and Technology
DOI: 10.1021/acsnano.9b08789

Boosting the Solar Cell Efficiency by Flexo-photovoltaic Effect?
DOI: 10.1021/acsnano.9b07222

Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy
DOI: 10.1021/acsnano.9b05425

Amorphous Fe–Ni–P–B–O Nanocages as Efficient Electrocatalysts for Oxygen Evolution Reaction
DOI: 10.1021/acsnano.9b05571

Sculpting Liquids with Two-Dimensional Materials: The Assembly of Ti3C2Tx MXene Sheets at Liquid–Liquid Interfaces
DOI: 10.1021/acsnano.9b05088


ACS Photonics

***

Multicolor High-Speed Tracking of Single Biomolecules with Silver, Gold, and Silver–Gold Alloy Nanoparticles
DOI: 10.1021/acsphotonics.9b00953

Converting an Organic Light-Emitting Diode from Blue to White with Bragg Modes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsphotonics.9b01206

Electrically Biased Silicon Metasurfaces with Magnetic Mie Resonance for Tunable Harmonic Generation of Light
DOI: 10.1021/acsphotonics.9b01398

Enhanced Fields in Mirror-Backed Low-Index Dielectric Structures
DOI: 10.1021/acsphotonics.9b00931

Reduced Density-Matrix Approach to Strong Matter-Photon Interaction
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsphotonics.9b00648


ACS Sensors

***

Protein–Polymer Block Copolymer Thin Films for Highly Sensitive Detection of Small Proteins in Biological Fluids
DOI: 10.1021/acssensors.9b01020

Ultrasensitive Chemiluminescence Biosensor for Nuclease and Bacterial Determination Based on Hemin-Encapsulated Mesoporous Silica Nanoparticles
DOI: 10.1021/acssensors.9b01303

Amperometric Aptasensor for Amyloid-β Oligomer Detection by Optimized Stem-Loop Structures with an Adjustable Detection Range
DOI: 10.1021/acssensors.9b01630

Paper-Based Microfluidic Device (DON-Chip) for Rapid and Low-Cost Deoxynivalenol Quantification in Food, Feed, and Feed Ingredients
DOI: 10.1021/acssensors.9b01895

Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssensors.9b01403


ACS Sustainable Chemistry & Engineering

***

Baltrusaitis, Barta, and Wang: 2020 Winners of the ACS Sustainable Chemistry & Engineering Lectureship Awards
DOI: 10.1021/acssuschemeng.9b06338

Tribochemical Degradation of Polytetrafluoroethylene in Water and Generation of Nanoplastics
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acssuschemeng.9b03573

Metal-Free Visible-Light-Induced Dithiol–Ene Clicking via Carbon Nitride to Valorize 4-Pentenoic Acid as a Functional Monomer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssuschemeng.9b05351

Valorization of Carbohydrates of Agricultural Residues and Food Wastes: A Key Strategy for Carbon Conservation
DOI: 10.1021/acssuschemeng.9b04242

Facile and Green Synthesis of Carboxylated Cellulose Nanocrystals as Efficient Adsorbents in Wastewater Treatments
DOI: 10.1021/acssuschemeng.9b05081


Bioconjugate Chemistry

***

Going Native: Synthesis of Glycoproteins and Glycopeptides via Native Linkages To Study Glycan-Specific Roles in the Immune System
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00588

Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy
DOI: 10.1021/acs.bioconjchem.9b00564

Hydrophilic Sequence-Defined Cross-Linkers for Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00713

Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00609

Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00548


Biomacromolecules

***

Interaction Pathways and Structure–Chemical Transformations of Alginate Gels in Physiological Environments
DOI: 10.1021/acs.bioconjchem.9b00548

Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.biomac.9b01341

Antimicrobial Peptide-Conjugated Hierarchical Antifouling Polymer Brushes for Functionalized Catheter Surfaces
DOI: 10.1021/acs.biomac.9b01060

Electrospinning Nanofibers from Chitosan/Hyaluronic Acid Complex Coacervates
DOI: 10.1021/acs.biomac.9b01072

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension
DOI: 10.1021/acs.biomac.9b00891


Chemistry of Materials

***

Negotiating Details in the Academic Letter of Offer
DOI: 10.1021/acs.chemmater.9b04051

An Electrifying Choice for the 2019 Chemistry Nobel Prize: Goodenough, Whittingham, and Yoshino
DOI: 10.1021/acs.chemmater.9b04345

Methods and Protocols for Reliable Electrochemical Testing in Post-Li Batteries (Na, K, Mg, and Ca)
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.chemmater.9b02776

Conjugated Carbonyl Compounds as High-Performance Cathode Materials for Rechargeable Batteries
DOI: 10.1021/acs.chemmater.9b03109

Understanding X-ray Spectroscopy of Carbonaceous Materials by Combining Experiments, Density Functional Theory, and Machine Learning. Part I: Fingerprint Spectra
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.chemmater.9b02049


Crystal Growth & Design

***

Crystallization of Anhydrous Proton from Acidic Aqueous Solution with Diamide Building Block
DOI: 10.1021/acs.cgd.9b01214

Surface Induced Phenytoin Polymorph. 1. Full Structure Solution by Combining Grazing Incidence X-ray Diffraction and Crystal Structure Prediction
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.cgd.9b00857

Polymorphism and Morphology Folklore
DOI: 10.1021/acs.cgd.9b00910

Crystal Structure Evidence for the Directionality of Lone Pair−π interactions: Fact or Fiction?
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.cgd.9b01081

New Doubly Interpenetrated MOF with [Zn4O] Clusters and Its Doped Isomorphic MOF: Sensing, Dye, and Gas Adsorption Capacity
DOI: 10.1021/acs.cgd.9b01193


Energy & Fuels

***

Evolution of Aromatic Structures during the Low-Temperature Electrochemical Upgrading of Bio-oil
DOI: 10.1021/acs.energyfuels.9b03099

NMR Spectroscopy Analysis of Asphaltenes
DOI: 10.1021/acs.energyfuels.9b02240

Biocrude Production from Fast and Isothermal Hydrothermal Liquefaction of Chitin
DOI: 10.1021/acs.energyfuels.9b03209

Adsorption of Methane, Nitrogen, and Carbon Dioxide in Atomic-Scale Fractal Nanopores by Monte Carlo Simulation I: Single-Component Adsorption
DOI: 10.1021/acs.energyfuels.9b01405

Alcohol-Assisted Waterflooding in Carbonate Reservoirs
DOI: 10.1021/acs.energyfuels.9b02497


Industrial & Engineering Chemistry Research

***

Preface to the Mohamed El-Aasser Festschrift
DOI: 10.1021/acs.iecr.9b05839

An Airlift Crystallizer for Protein Crystallization
DOI: 10.1021/acs.iecr.9b03535

Superelastic and Durable Hierarchical Porous Thermoplastic Polyurethane Monolith with Excellent Hydrophobicity for Highly Efficient Oil/Water Separation
DOI: 10.1021/acs.iecr.9b03717

Advanced Amino Acid-Based Technologies for CO2 Capture: A Review
DOI: 10.1021/acs.iecr.9b01793

Predicting Metal–Support Interactions in Oxide-Supported Single-Atom Catalysts
DOI: 10.1021/acs.iecr.9b04068


Inorganic Chemistry

***

Supramolecular Anchoring of Octahedral Molybdenum Clusters onto Graphene and Their Synergies in Photocatalytic Water Reduction
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.inorgchem.9b02529

Viewpoint: Atomic-Scale Design Protocols toward Energy, Electronic, Catalysis, and Sensing Applications
DOI: 10.1021/acs.inorgchem.9b01785

Terbium Triangle Bridged by a Triazole Nitronyl Nitroxide Radical with Single-Molecule-Magnet Behavior
DOI: 10.1021/acs.inorgchem.9b01647

Electronic Structure of Tetracyanonickelate(II)
DOI: 10.1021/acs.inorgchem.9b02135

Redox Tuning via Ligand-Induced Geometric Distortions at a YMn3O4 Cubane Model of the Biological Oxygen Evolving Complex
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.inorgchem.9b00510


Journal of Chemical & Engineering Data

***

Celebrating JCED’s High Impact Authors
DOI: 10.1021/acs.jced.9b01050

Taking Another Look at the van der Waals Equation of State–Almost 150 Years Later
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jced.9b00264

Liquid Properties of Ionic Liquids Based on Phosphonium Cations with (Alkylthio)alkyl Groups
DOI: 10.1021/acs.jced.9b00033

Peroxidase Mimic Activity of Au–Ag/l-Cys-rGO Nanozyme toward Detection of Cr(VI) Ion in Water: Role of 3,3′,5,5′-Tetramethylbenzidine Adsorption
DOI: 10.1021/acs.jced.9b00819

Solubility and Diffusivity of Oxygen in Ionic Liquids
DOI: 10.1021/acs.jced.9b00750


The Journal of Physical Chemistry C

***

Getting the Right Twist: Influence of Donor–Acceptor Dihedral Angle on Exciton Kinetics and Singlet–Triplet Gap in Deep Blue Thermally Activated Delayed Fluorescence Emitter
DOI: 10.1021/acs.jpcc.9b08269

Film Conformality and Extracted Recombination Probabilities of O Atoms during Plasma-Assisted Atomic Layer Deposition of SiO2, TiO2, Al2O3, and HfO2
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b08176

Theory of Impedance Spectroscopy for Lithium Batteries
DOI: 10.1021/acs.jpcc.9b07389

Charge Transfer during the Dissociation of H2 and the Charge State of H Atoms in Liquid Gallium
DOI: 10.1021/acs.jpcc.9b06779

Transmission Line Model for Description of the Impedance Response of Li Electrodes with Dendritic Growth
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b05887


The Journal of Physical Chemistry Letters

***

Singlet Fission in Crystalline Organic Materials: Recent Insights and Future Directions
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpclett.9b00754

Two-Dimensional Ferroics and Multiferroics: Platforms for New Physics and Applications
DOI: 10.1021/acs.jpclett.9b01969

Ultrafast Tracking of Exciton and Charge Carrier Transport in Optoelectronic Materials on the Nanometer Scale
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpclett.9b02437

Carrier Extraction from Perovskite to Polymeric Charge Transport Layers Probed by Ultrafast Transient Absorption Spectroscopy
DOI: 10.1021/acs.jpclett.9b02502

CsPbBr3 Perovskite Nanocrystal Grown on MXene Nanosheets for Enhanced Photoelectric Detection and Photocatalytic CO2 Reduction
DOI: 10.1021/acs.jpclett.9b02605


Langmuir

***

Dynamic Landscape in Self-Assembled Surfactant Aggregates
DOI: 10.1021/acs.langmuir.8b03596

Patterned SiO2/Polyurethane Acrylate Inverse Opal Photonic Crystals with High Color Saturation and Tough Mechanical Strength
DOI: 10.1021/acs.langmuir.9b02485

Smart Amphiphilic Random Copolymer-Coated Sponge with pH-Switchable Wettability for On-Demand Oil/Water Separation
DOI: 10.1021/acs.langmuir.9b02583

Chemical Reactions Involving the Surface of Metal Chalcogenide Quantum Dots
DOI: 10.1021/acs.langmuir.9b01285

Fluorescence Solvatochromism of Carbon Dot Dispersions Prepared from Phenylenediamine and Optimization of Red Emission
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.langmuir.9b02739


Macromolecules

***

Reprocessable Polymer Networks via Thiourethane Dynamic Chemistry: Recovery of Cross-link Density after Recycling and Proof-of-Principle Solvolysis Leading to Monomer Recovery
DOI: 10.1021/acs.macromol.9b01359

Molecular-Spring Shape-Memory Polymer Based on Energy Elasticity and Local Phase Transition
DOI: 10.1021/acs.macromol.9b01636

Monodisperse Liquid Crystal Network Particles Synthesized via Precipitation Polymerization
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.macromol.9b01852

Surface Nanostructures Fabricated by Polymerization-Induced Surface Self-Assembly
DOI: 10.1021/acs.macromol.9b01664

Controlling Healing and Toughness in Polyurethanes by Branch-Mediated Tube Dilation
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.macromol.9b01554


Nano Letters

***

Dual-Enhanced Raman Scattering-Based Characterization of Stem Cell Differentiation Using Graphene-Plasmonic Hybrid Nanoarray
DOI: 10.1021/acs.nanolett.9b03402

Triggered All-Active Metal Organic Framework: Ferroptosis Machinery Contributes to the Apoptotic Photodynamic Antitumor Therapy
DOI: 10.1021/acs.nanolett.9b02904

Waveguide-Integrated, Plasmonic Enhanced Graphene Photodetectors
DOI: 10.1021/acs.nanolett.9b02238

Plasmonic Nanopores for Single-Molecule Detection and Manipulation: Toward Sequencing Applications
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.nanolett.9b02759

Chasing Plasmons in Flatland
DOI: 10.1021/acs.nanolett.9b04349


Discover the Most-Read Biological Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Applied Bio Materials
***

Doxorubicin–Metal Coordinated Micellar Nanoparticles for Intracellular Codelivery and Chemo/Chemodynamic Therapy in Vitro
DOI: 10.1021/acsabm.9b00879

Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy
DOI: 10.1021/acsabm.9b00763

Stabilization of Fibronectin by Random Copolymer Brushes Inhibits Macrophage Activation
DOI: 10.1021/acsabm.9b00815

NIR-Triggered Theranostic Bi2S3 Light Transducer for On-Demand NO Release and Synergistic Gas/Photothermal Combination Therapy of Tumors
DOI: 10.1021/acsabm.9b00522

Engineering Human-Scale Artificial Bone Grafts for Treating Critical-Size Bone Defects
DOI: 10.1021/acsabm.9b00756


ACS Biomaterials Science & Engineering

***

Interfacial Diffusion Printing: An Efficient Manufacturing Technique for Artificial Tubular Grafts
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsbiomaterials.9b01293

Metal–Organic Framework-Integrated Enzymes as Bioreactor for Enhanced Therapy against Solid Tumor via a Cascade Catalytic Reaction
DOI: 10.1021/acsbiomaterials.9b01200

Modular Assembly of Biomaterials Using Polyphenols as Building Blocks
DOI: 10.1021/acsbiomaterials.8b01507

Submicron Patterns-on-a-Chip: Fabrication of a Microfluidic Device Incorporating 3D Printed Surface Ornaments
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.9b01155

3,4-Dihydroxyphenylalanine (DOPA)-Containing Silk Fibroin: Its Enzymatic Synthesis and Adhesion Properties
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.8b01309


ACS Catalysis

***

Operando Insights into Nanoparticle Transformations during Catalysis
Open Access Through ACS AuthorChoice
DOI: 10.1021/acscatal.9b01831

Recent Insights into the Oxygen-Reduction Electrocatalysis of Fe/N/C Materials
DOI: 10.1021/acscatal.9b02583

Copper Single Atoms Anchored in Porous Nitrogen-Doped Carbon as Efficient pH-Universal Catalysts for the Nitrogen Reduction Reaction
DOI: 10.1021/acscatal.9b02944

Site-Selective C–H Acylation of Pyridinium Derivatives by Photoredox Catalysis
DOI: 10.1021/acscatal.9b03367

Recent Advances and Prospective in Ruthenium-Based Materials for Electrochemical Water Splitting
DOI: 10.1021/acscatal.9b02457


ACS Chemical Biology

***

Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
DOI: 10.1021/acschembio.8b01083

Chemical Modulation of Human Mitochondrial ClpP: Potential Application in Cancer Therapeutics
DOI: 10.1021/acschembio.9b00347

DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation
This article is part of the Proteolytic Regulation of Cellular Physiology special issue.
Open Access Through ACS AuthorChoice
DOI: 10.1021/acschembio.9b00462

Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs)
This article is part of the Proteolytic Regulation of Cellular Physiology special issue.
Open Access Through ACS AuthorChoice
DOI: 10.1021/acschembio.9b00402

Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3
DOI: 10.1021/acschembio.9b00564


ACS Chemical Neuroscience

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In Vivo Assessment of Retinal Biomarkers by Hyperspectral Imaging: Early Detection of Alzheimer’s Disease
DOI: 10.1021/acschemneuro.9b00331

NeuroChat with Professor David Olson
DOI: 10.1021/acschemneuro.9b00513

Modeling and Structural Characterization of the Sweet Taste Receptor Heterodimer
DOI: 10.1021/acschemneuro.9b00438

NeuroChat with Professor Corey R. Hopkins
DOI: 10.1021/acschemneuro.9b00526

Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acschemneuro.9b00390


ACS Infectious Diseases

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Ureadepsipeptides as ClpP Activators
DOI: 10.1021/acsinfecdis.9b00245

Antagonistic Interaction of Staphylococcus aureus and Staphylococcus epidermidis with Rhizopus arrhizus Mediated by Phenol Soluble Modulins and Organic Acids
DOI: 10.1021/acsinfecdis.9b00205

A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68
DOI: 10.1021/acsinfecdis.9b00284

Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov–Doebner Reactions
DOI: 10.1021/acsinfecdis.9b00022

Conformational Dynamics of AcrA Govern Multidrug Efflux Pump Assembly
DOI: 10.1021/acsinfecdis.9b00273


ACS Medicinal Chemistry Letters

***

Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
DOI: 10.1021/acsmedchemlett.9b00381

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
DOI: 10.1021/acsmedchemlett.9b00141

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
DOI: 10.1021/acsmedchemlett.9b00377

Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation
DOI: 10.1021/acsmedchemlett.9b00409

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy
DOI: 10.1021/acsmedchemlett.9b00344


ACS Synthetic Biology

***

CReasPy-Cloning: A Method for Simultaneous Cloning and Engineering of Megabase-Sized Genomes in Yeast Using the CRISPR-Cas9 System
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssynbio.9b00224

Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acssynbio.9b00258

A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells
DOI: 10.1021/acssynbio.9b00322

Exploring Chemical Biosynthetic Design Space with Transform-MinER
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssynbio.9b00105

Interkingdom Genetic Mix-and-Match To Produce Novel Sunscreens
DOI: 10.1021/acssynbio.9b00352


Biochemistry

***

Rebooting the Epigenome: Erasure of Parental Histone Marks for Establishing the Regulatory Landscape in Zygotes
DOI: 10.1021/acs.biochem.9b00815

Development of an Efficient Enzyme Production and Structure-Based Discovery Platform for BACE1 Inhibitors
DOI: 10.1021/acs.biochem.9b00714

Discovery of Amidotemplated Natural Product Assembly
DOI: 10.1021/acs.biochem.9b00928

Catalytic M Center of Copper Monooxygenases Probed by Rational Design. Effects of Selenomethionine and Histidine Substitution on Structure and Reactivity
DOI: 10.1021/acs.biochem.9b00823

Drivers of α-Sheet Formation in Transthyretin under Amyloidogenic Conditions
DOI: 10.1021/acs.biochem.9b00769


Bioconjugate Chemistry

***

Going Native: Synthesis of Glycoproteins and Glycopeptides via Native Linkages To Study Glycan-Specific Roles in the Immune System
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00588

Hypoxia-Activated and Indomethacin-Mediated Theranostic Prodrug Releasing Drug On-Demand for Tumor Imaging and Therapy
DOI: 10.1021/acs.bioconjchem.9b00564

Hydrophilic Sequence-Defined Cross-Linkers for Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00713

Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody–Drug Conjugates
DOI: 10.1021/acs.bioconjchem.9b00609

Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody–DNA Conjugates
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.bioconjchem.9b00548


Biomacromolecules

***

Interaction Pathways and Structure–Chemical Transformations of Alginate Gels in Physiological Environments
DOI: 10.1021/acs.biomac.9b01052

Adaptive Polymeric Assemblies for Applications in Biomimicry and Nanomedicine
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.biomac.9b01341

Antimicrobial Peptide-Conjugated Hierarchical Antifouling Polymer Brushes for Functionalized Catheter Surfaces
DOI: 10.1021/acs.biomac.9b01060

Electrospinning Nanofibers from Chitosan/Hyaluronic Acid Complex Coacervates
DOI: 10.1021/acs.biomac.9b01072

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension
DOI: 10.1021/acs.biomac.9b00891


Journal of Agricultural and Food Chemistry

***

Reclaiming Phosphate from Waste Solutions with Fe(III)–Polysaccharide Hydrogel Beads for Photo-Controlled-Release Fertilizer
DOI: 10.1021/acs.jafc.9b02860

Supplementation of Sesamin Alleviates Stress-Induced Behavioral and Psychological Disorders via Reshaping the Gut Microbiota Structure
DOI: 10.1021/acs.jafc.9b03652

Discovery of Novel Isothiazole, 1,2,3-Thiadiazole, and Thiazole-Based Cinnamamides as Fungicidal Candidates
DOI: 10.1021/acs.jafc.9b03891

Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases
DOI: 10.1021/acs.jafc.9b04073

Application of a Plant Biostimulant To Improve Maize (Zea mays) Tolerance to Metolachlor
DOI: 10.1021/acs.jafc.9b04949


Journal of Chemical Theory and Computation

***

OpenMolcas: From Source Code to Insight
DOI: 10.1021/acs.jctc.9b00532

HFLD: A Nonempirical London Dispersion-Corrected Hartree–Fock Method for the Quantification and Analysis of Noncovalent Interaction Energies of Large Molecular Systems
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00425

String Method for Protein–Protein Binding Free-Energy Calculations
DOI: 10.1021/acs.jctc.9b00499

Less Is More: Coarse-Grained Integrative Modeling of Large Biomolecular Assemblies with HADDOCK
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00310

MemSurfer: A Tool for Robust Computation and Characterization of Curved Membranes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00453


Journal of Medicinal Chemistry

***

How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining
DOI: 10.1021/acs.jmedchem.9b01545

Overview of Recent Strategic Advances in Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b00359

Halogens in Protein–Ligand Binding Mechanism: A Structural Perspective
DOI: 10.1021/acs.jmedchem.8b01453

The Blood–Brain Barrier (BBB) Score
DOI: 10.1021/acs.jmedchem.9b01220

Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
DOI: 10.1021/acs.jmedchem.9b00846


Journal of Natural Products

***

Ealamines A–H, a Series of Naphthylisoquinolines with the Rare 7,8′-Coupling Site, from the Congolese Liana Ancistrocladus ealaensis, Targeting Pancreatic Cancer Cells
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jnatprod.9b00755

Terpenoids from the Stems of Fissistigma polyanthoides and Their Anti-Inflammatory Activity
DOI: 10.1021/acs.jnatprod.9b00208

Total Synthesis of Clavatadine B
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jnatprod.9b00813

Anti-inflammatory and α-Glucosidase Inhibitory Activities of Labdane and Norlabdane Diterpenoids from the Rhizomes of Amomum villosum
DOI: 10.1021/acs.jnatprod.9b00283

Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
DOI: 10.1021/acs.jnatprod.8b00380


The Journal of Physical Chemistry B

***

Energy Transport across Interfaces in Biomolecular Systems
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07086

Halogen Bonding beyond Crystals in Materials Science
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07035

Solubility of Caffeine in Supercritical CO2: A Molecular Dynamics Simulation Study
DOI: 10.1021/acs.jpcb.9b08351

Hydrogen Abstraction of Ketoprofen in the Excited Triplet State with Indole and Methylindoles
DOI: 10.1021/acs.jpcb.9b06786

Interaction and Dynamics in a Fully Biodegradable Glucose-Containing Naturally Abundant Deep Eutectic Solvent: Temperature-Dependent Time-Resolved Fluorescence Measurements
DOI: 10.1021/acs.jpcb.9b06783


The Journal of Physical Chemistry Letters

***

Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
DOI: 10.1021/acsmedchemlett.9b00381

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
DOI: 10.1021/acsmedchemlett.9b00141

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
DOI: 10.1021/acsmedchemlett.9b00377

Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation
DOI: 10.1021/acsmedchemlett.9b00409

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy
DOI: 10.1021/acsmedchemlett.9b00344


Journal of Proteome Research

***

MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics
DOI: 10.1021/acs.jproteome.9b00313

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
DOI: 10.1021/acs.jproteome.9b00500

Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model
DOI: 10.1021/acs.jproteome.9b00492

Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
DOI: 10.1021/acs.jproteome.9b00481

Vegetative Cell and Spore Proteomes of Clostridioides difficile Show Finite Differences and Reveal Potential Protein Markers
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jproteome.9b00413


Molecular Pharmaceutics

***

A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies
DOI: 10.1021/acs.molpharmaceut.9b00519

Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
DOI: 10.1021/acs.molpharmaceut.9b00361

Molecular Engineering of Adeno-Associated Virus Capsid Improves Its Therapeutic Gene Transfer in Murine Models of Hemophilia and Retinal Degeneration
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00959

Bioconjugation of Cyclometalated Gold(III) Lipoic Acid Fragments to Linear and Cyclic Breast Cancer Targeting Peptides
DOI: 10.1021/acs.molpharmaceut.9b00695

Deep Convolutional Generative Adversarial Network (dcGAN) Models for Screening and Design of Small Molecules Targeting Cannabinoid Receptors
DOI: 10.1021/acs.molpharmaceut.9b00500


Discover the Most-Read Applied Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Applied Materials & Interfaces

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Plastic-like Hydrogels with Reversible Conversion of Elasticity and Plasticity and Tunable Mechanical Properties
DOI: 10.1021/acsami.9b14158

Transparent, Antifreezing, Ionic Conductive Cellulose Hydrogel with Stable Sensitivity at Subzero Temperature
DOI: 10.1021/acsami.9b15849

Highly Compressible and Robust Polyimide/Carbon Nanotube Composite Aerogel for High-Performance Wearable Pressure Sensor
DOI: 10.1021/acsami.9b14688

Boosting the Photocatalytic Ability of g-C3N4 for Hydrogen Production by Ti3C2 MXene Quantum Dots
DOI: 10.1021/acsami.9b14985

Engineering of Nitrogen Coordinated Single Cobalt Atom Moieties for Oxygen Electroreduction
DOI: 10.1021/acsami.9b11830


ACS Applied Bio Materials

Doxorubicin–Metal Coordinated Micellar Nanoparticles for Intracellular Codelivery and Chemo/Chemodynamic Therapy in Vitro
DOI: 10.1021/acsabm.9b00879

Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy
DOI: 10.1021/acsabm.9b00763

Stabilization of Fibronectin by Random Copolymer Brushes Inhibits Macrophage Activation
DOI: 10.1021/acsabm.9b00815

NIR-Triggered Theranostic Bi2S3 Light Transducer for On-Demand NO Release and Synergistic Gas/Photothermal Combination Therapy of Tumors
DOI: 10.1021/acsabm.9b00522

Engineering Human-Scale Artificial Bone Grafts for Treating Critical-Size Bone Defects
DOI: 10.1021/acsabm.9b00756


ACS Applied Electronic Materials

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Carbonized Chinese Art Paper-Based High-Performance Wearable Strain Sensor for Human Activity Monitoring
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsaelm.9b00564

Performance Improvement of Multilayered SnS2 Field Effect Transistors through Synergistic Effect of Vacancy Repairing and Electron Doping Introduced by EDTA
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsaelm.9b00550

Film-Nanostructure-Controlled Inerasable-to-Erasable Switching Transition in ZnO-Based Transparent Memristor Devices: Sputtering-Pressure Dependency
DOI: 10.1021/acsaelm.9b00617

Non-Rare-Earth Na3AlF6:Cr3+ Phosphors for Far-Red Light-Emitting Diodes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaelm.9b00527

Great Differences between Low-Temperature Grown Co2FeSi and Co2MnSi Films on Single-Crystalline Oxides
DOI: 10.1021/acsaelm.9b00546


ACS Applied Energy Materials

***

Cathodic Hydrogen Peroxide Electrosynthesis Using Anthraquinone Modified Carbon Nitride on Gas Diffusion Electrode
DOI: 10.1021/acsaem.9b01445

Efficient Solar Water Splitting Photocathodes Comprising a Copper Oxide Heterostructure Protected by a Thin Carbon Layer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01290

Hydrophobic Side-Chain Attached Polyarylether-Based Anion Exchange Membranes with Enhanced Alkaline Stability
DOI: 10.1021/acsaem.9b01553

Ag–TiO2 Hybrid Nanocrystal Photocatalyst: Hydrogen Evolution under UV Irradiation but Not under Visible-Light Irradiation
DOI: 10.1021/acsaem.9b01730

Double-Shelled Co3O4/C Nanocages Enabling Polysulfides Adsorption for High-Performance Lithium–Sulfur Batteries
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsaem.9b01621


ACS Applied Nano Materials

***

Carboxyl-Functionalized Covalent Organic Frameworks for the Adsorption and Removal of Triphenylmethane Dyes
DOI: 10.1021/acsanm.9b01781

TiO2 Nanofilms on Polymeric Substrates for the Photocatalytic Degradation of Methylene Blue
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsanm.9b01723

Solid-Phase Epitaxy of Perovskite High Dielectric PrAlO3 Films Grown by Atomic Layer Deposition for Use in Two-Dimensional Electronics and Memory Devices
DOI: 10.1021/acsanm.9b02153

Plasmonic Nanocavity Metasurface Based on Laser-Structured Silver Surface and Silver Nanoprisms for the Enhancement of Adenosine Nucleotide Photoluminescence
DOI: 10.1021/acsanm.9b01673

Graphene Nanofluids as Thermal Management Materials: Molecular Dynamics Study on Orientation and Temperature Effects
DOI: 10.1021/acsanm.9b01266


ACS Applied Polymer Materials

***

Degradable Thermoset Fibers from Carbohydrate-Derived Diols via Thiol–Ene Photopolymerization
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsapm.9b00647

Damage-Reporting Carbon Fiber Epoxy Composites
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsapm.9b00694

Luminescent Solar Concentrators Based on Energy Transfer from an Aggregation-Induced Emitter Conjugated Polymer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsapm.9b00718

Mussel-Inspired Tough Double Network Hydrogel As Transparent Adhesive
DOI: 10.1021/acsapm.9b00698

Microfluidic Channels Fabrication Based on Underwater Superpolymphobic Microgrooves Produced by Femtosecond Laser Direct Writing
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsapm.9b00269


ACS Biomaterials Science & Engineering

***

Interfacial Diffusion Printing: An Efficient Manufacturing Technique for Artificial Tubular Grafts
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acsbiomaterials.9b01293

Metal–Organic Framework-Integrated Enzymes as Bioreactor for Enhanced Therapy against Solid Tumor via a Cascade Catalytic Reaction
DOI: 10.1021/acsbiomaterials.9b01200

Modular Assembly of Biomaterials Using Polyphenols as Building Blocks
DOI: 10.1021/acsbiomaterials.8b01507

Submicron Patterns-on-a-Chip: Fabrication of a Microfluidic Device Incorporating 3D Printed Surface Ornaments
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.9b01155

3,4-Dihydroxyphenylalanine (DOPA)-Containing Silk Fibroin: Its Enzymatic Synthesis and Adhesion Properties
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsbiomaterials.8b01309


ACS Combinatorial Science

***

Calculating Resin Functionalization in Solid-Phase Peptide Synthesis Using a Standardized Method based on Fmoc Determination
DOI: 10.1021/acscombsci.9b00154

Cleaning Matters!
DOI: 10.1021/acscombsci.9b00122

Metric Learning for High-Throughput Combinatorial Data Sets
DOI: 10.1021/acscombsci.9b00086

Profiling Protein Tyrosine Phosphatase Specificity with Self-Assembled Monolayers for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Peptide Arrays
DOI: 10.1021/acscombsci.9b00152

Alloyed Thermoelectric PbTe–SnTe Films Formed via Aerosol Deposition
DOI: 10.1021/acscombsci.9b00145


ACS Energy Letters

***

2019 Nobel Prize for the Li-Ion Batteries and New Opportunities and Challenges in Na-Ion Batteries
DOI: 10.1021/acsenergylett.9b02190

Lithium-Ion Batteries and Beyond: Celebrating the 2019 Nobel Prize in Chemistry – A Virtual Issue
DOI: 10.1021/acsenergylett.9b02280

Direct Synthesis of Quaternary Alkylammonium-Capped Perovskite Nanocrystals for Efficient Blue and Green Light-Emitting Diodes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acsenergylett.9b01915

Industrial Insights into Perovskite Photovoltaics
DOI: 10.1021/acsenergylett.9b02105

New Insight on the Role of Electrolyte Additives in Rechargeable Lithium Ion Batteries
DOI: 10.1021/acsenergylett.9b01441


ACS Infectious Diseases

***

Ureadepsipeptides as ClpP Activators
DOI: 10.1021/acsinfecdis.9b00245

Antagonistic Interaction of Staphylococcus aureus and Staphylococcus epidermidis with Rhizopus arrhizus Mediated by Phenol Soluble Modulins and Organic Acids
DOI: 10.1021/acsinfecdis.9b00205

A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68
DOI: 10.1021/acsinfecdis.9b00284

Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov–Doebner Reactions
DOI: 10.1021/acsinfecdis.9b00022

Conformational Dynamics of AcrA Govern Multidrug Efflux Pump Assembly
DOI: 10.1021/acsinfecdis.9b00273


ACS Medicinal Chemistry Letters

***

Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors
DOI: 10.1021/acsmedchemlett.9b00381

Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
DOI: 10.1021/acsmedchemlett.9b00141

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis
DOI: 10.1021/acsmedchemlett.9b00377

Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation
DOI: 10.1021/acsmedchemlett.9b00409

Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy
DOI: 10.1021/acsmedchemlett.9b00344


ACS Sensors

***

Protein–Polymer Block Copolymer Thin Films for Highly Sensitive Detection of Small Proteins in Biological Fluids
DOI: 10.1021/acssensors.9b01020

Ultrasensitive Chemiluminescence Biosensor for Nuclease and Bacterial Determination Based on Hemin-Encapsulated Mesoporous Silica Nanoparticles
DOI: 10.1021/acssensors.9b01303

Amperometric Aptasensor for Amyloid-β Oligomer Detection by Optimized Stem-Loop Structures with an Adjustable Detection Range
DOI: 10.1021/acssensors.9b01630

Paper-Based Microfluidic Device (DON-Chip) for Rapid and Low-Cost Deoxynivalenol Quantification in Food, Feed, and Feed Ingredients
DOI: 10.1021/acssensors.9b01895

Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssensors.9b01403


ACS Sustainable Chemistry & Engineering

***

Baltrusaitis, Barta, and Wang: 2020 Winners of the ACS Sustainable Chemistry & Engineering Lectureship Awards
DOI: 10.1021/acssuschemeng.9b06338

Tribochemical Degradation of Polytetrafluoroethylene in Water and Generation of Nanoplastics
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acssuschemeng.9b03573

Metal-Free Visible-Light-Induced Dithiol–Ene Clicking via Carbon Nitride to Valorize 4-Pentenoic Acid as a Functional Monomer
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssuschemeng.9b05351

Valorization of Carbohydrates of Agricultural Residues and Food Wastes: A Key Strategy for Carbon Conservation
DOI: 10.1021/acssuschemeng.9b04242

Facile and Green Synthesis of Carboxylated Cellulose Nanocrystals as Efficient Adsorbents in Wastewater Treatments
DOI: 10.1021/acssuschemeng.9b05081


ACS Synthetic Biology

***

CReasPy-Cloning: A Method for Simultaneous Cloning and Engineering of Megabase-Sized Genomes in Yeast Using the CRISPR-Cas9 System
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssynbio.9b00224

Model-Assisted Fine-Tuning of Central Carbon Metabolism in Yeast through dCas9-Based Regulation
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acssynbio.9b00258

A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells
DOI: 10.1021/acssynbio.9b00322

Exploring Chemical Biosynthetic Design Space with Transform-MinER
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssynbio.9b00105

Interkingdom Genetic Mix-and-Match To Produce Novel Sunscreens
DOI: 10.1021/acssynbio.9b00352


Analytical Chemistry

***

Deciphering Metabolic Heterogeneity by Single-Cell Analysis
DOI: 10.1021/acs.analchem.9b02410

Welcome JASMS to the ACS Measurement Science Family
DOI: 10.1021/acs.analchem.9b04705

Pacifier Biosensor: Toward Noninvasive Saliva Biomarker Monitoring
DOI: 10.1021/acs.analchem.9b03379

Versatile Electrochemiluminescence and Photoelectrochemical Detection of Glutathione Using Mn2+ Substitute Target by DNA-Walker-Induced Allosteric Switch and Signal Amplification
DOI: 10.1021/acs.analchem.9b03990

Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues
DOI: 10.1021/acs.analchem.9b03617


Chemical Research in Toxicology

***

Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
DOI: 10.1021/acs.chemrestox.9b00339

Computational Investigation of Drug Phototoxicity: Photosafety Assessment, Photo-Toxophore Identification, and Machine Learning
DOI: 10.1021/acs.chemrestox.9b00338

Toxicokinetic–Toxicodynamic Modeling of the Effects of Pesticides on Growth of Rattus norvegicus
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.chemrestox.9b00294

MiR-326 Inhibits Inflammation and Promotes Autophagy in Silica-Induced Pulmonary Fibrosis through Targeting TNFSF14 and PTBP1
DOI: 10.1021/acs.chemrestox.9b00194

Methods and Challenges for Computational Data Analysis for DNA Adductomics
DOI: 10.1021/acs.chemrestox.9b00196


Crystal Growth & Design

***

Crystallization of Anhydrous Proton from Acidic Aqueous Solution with Diamide Building Block
DOI: 10.1021/acs.cgd.9b01214

Surface Induced Phenytoin Polymorph. 1. Full Structure Solution by Combining Grazing Incidence X-ray Diffraction and Crystal Structure Prediction
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.cgd.9b00857

Polymorphism and Morphology Folklore
DOI: 10.1021/acs.cgd.9b00910

Crystal Structure Evidence for the Directionality of Lone Pair−π interactions: Fact or Fiction?
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.cgd.9b01081

New Doubly Interpenetrated MOF with [Zn4O] Clusters and Its Doped Isomorphic MOF: Sensing, Dye, and Gas Adsorption Capacity
DOI: 10.1021/acs.cgd.9b01193


Energy & Fuels

***

Evolution of Aromatic Structures during the Low-Temperature Electrochemical Upgrading of Bio-oil
DOI: 10.1021/acs.energyfuels.9b03099

NMR Spectroscopy Analysis of Asphaltenes
DOI: 10.1021/acs.energyfuels.9b02240

Biocrude Production from Fast and Isothermal Hydrothermal Liquefaction of Chitin
DOI: 10.1021/acs.energyfuels.9b03209

Adsorption of Methane, Nitrogen, and Carbon Dioxide in Atomic-Scale Fractal Nanopores by Monte Carlo Simulation I: Single-Component Adsorption
DOI: 10.1021/acs.energyfuels.9b01405

Alcohol-Assisted Waterflooding in Carbonate Reservoirs
DOI: 10.1021/acs.energyfuels.9b02497


Environmental Science & Technology

***

Plastic Teabags Release Billions of Microparticles and Nanoparticles into Tea
DOI: 10.1021/acs.est.9b02540

Environmental Science & Technology Presents the 2019 Reviewer Awards
DOI: 10.1021/acs.est.9b05993

On the Road to Paris: The Shifting Landscape of CO2 Reduction
DOI: 10.1021/acs.est.9b05909

Adaptation of Black Carbon Footprint Concept Would Accelerate Mitigation of Global Warming
DOI: 10.1021/acs.est.9b05586

Surficial Sediment from the Milwaukee River Basin to Lake Michigan
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.est.9b03850


Environmental Science & Technology Letters

***

Sunlight Converts Polystyrene to Carbon Dioxide and Dissolved Organic Carbon
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.estlett.9b00532

Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.estlett.9b00582

Environmental Science & Technology Letters Presents the 2019 Excellence in Review Awards
DOI: 10.1021/acs.estlett.9b00632

Fate of Per- and Polyfluoroalkyl Ether Acids in the Total Oxidizable Precursor Assay and Implications for the Analysis of Impacted Water
DOI: 10.1021/acs.estlett.9b00525

Polyethylene Terephthalate and Polycarbonate Microplastics in Sewage Sludge Collected from the United States
DOI: 10.1021/acs.estlett.9b00601


Industrial & Engineering Chemistry Research

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Preface to the Mohamed El-Aasser Festschrift
DOI: 10.1021/acs.iecr.9b05839

An Airlift Crystallizer for Protein Crystallization
DOI: 10.1021/acs.iecr.9b03535

Superelastic and Durable Hierarchical Porous Thermoplastic Polyurethane Monolith with Excellent Hydrophobicity for Highly Efficient Oil/Water Separation
DOI: 10.1021/acs.iecr.9b03717

Advanced Amino Acid-Based Technologies for CO2 Capture: A Review
DOI: 10.1021/acs.iecr.9b01793

Predicting Metal–Support Interactions in Oxide-Supported Single-Atom Catalysts
DOI: 10.1021/acs.iecr.9b04068


Journal of Agricultural and Food Chemistry

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Reclaiming Phosphate from Waste Solutions with Fe(III)–Polysaccharide Hydrogel Beads for Photo-Controlled-Release Fertilizer
DOI: 10.1021/acs.jafc.9b02860

Supplementation of Sesamin Alleviates Stress-Induced Behavioral and Psychological Disorders via Reshaping the Gut Microbiota Structure
DOI: 10.1021/acs.jafc.9b03652

Discovery of Novel Isothiazole, 1,2,3-Thiadiazole, and Thiazole-Based Cinnamamides as Fungicidal Candidates
DOI: 10.1021/acs.jafc.9b03891

Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases
DOI: 10.1021/acs.jafc.9b04073

Application of a Plant Biostimulant To Improve Maize (Zea mays) Tolerance to Metolachlor
DOI: 10.1021/acs.jafc.9b04949


Journal of Chemical & Engineering Data

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Celebrating JCED’s High Impact Authors
DOI: 10.1021/acs.jced.9b01050

Taking Another Look at the van der Waals Equation of State–Almost 150 Years Later
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jced.9b00264

Liquid Properties of Ionic Liquids Based on Phosphonium Cations with (Alkylthio)alkyl Groups
DOI: 10.1021/acs.jced.9b00033

Peroxidase Mimic Activity of Au–Ag/l-Cys-rGO Nanozyme toward Detection of Cr(VI) Ion in Water: Role of 3,3′,5,5′-Tetramethylbenzidine Adsorption
DOI: 10.1021/acs.jced.9b00819

Solubility and Diffusivity of Oxygen in Ionic Liquids
DOI: 10.1021/acs.jced.9b00750


Journal of Chemical Information and Modeling

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Designing DNA Encoded Libraries of Diverse Products in a Focused Property Space
DOI: 10.1021/acs.jcim.9b00729

Prediction of Oral Bioavailability in Rats: Transferring Insights from in Vitro Correlations to (Deep) Machine Learning Models Using in Silico Model Outputs and Chemical Structure Parameters
DOI: 10.1021/acs.jcim.9b00460

Deep Transferable Compound Representation across Domains and Tasks for Low Data Drug Discovery
DOI: 10.1021/acs.jcim.9b00626

Incorporating Explicit Water Molecules and Ligand Conformation Stability in Machine-Learning Scoring Functions
DOI: 10.1021/acs.jcim.9b00645

AntiBac-Pred: A Web Application for Predicting Antibacterial Activity of Chemical Compounds
DOI: 10.1021/acs.jcim.9b00436


Journal of Chemical Theory and Computation

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OpenMolcas: From Source Code to Insight
DOI: 10.1021/acs.jctc.9b00532

HFLD: A Nonempirical London Dispersion-Corrected Hartree–Fock Method for the Quantification and Analysis of Noncovalent Interaction Energies of Large Molecular Systems
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00425

String Method for Protein–Protein Binding Free-Energy Calculations
DOI: 10.1021/acs.jctc.9b00499

Less Is More: Coarse-Grained Integrative Modeling of Large Biomolecular Assemblies with HADDOCK
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00310

MemSurfer: A Tool for Robust Computation and Characterization of Curved Membranes
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jctc.9b00453


Journal of Medicinal Chemistry

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How Significant Are Unusual Protein–Ligand Interactions? Insights from Database Mining
DOI: 10.1021/acs.jmedchem.9b01545

Overview of Recent Strategic Advances in Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b00359

Halogens in Protein–Ligand Binding Mechanism: A Structural Perspective
DOI: 10.1021/acs.jmedchem.8b01453

The Blood–Brain Barrier (BBB) Score
DOI: 10.1021/acs.jmedchem.9b01220

Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
DOI: 10.1021/acs.jmedchem.9b00846


The Journal of Physical Chemistry A

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Virtual Issue on Astrochemistry: From the Chemical Laboratory to the Stars
DOI: 10.1021/acs.jpca.9b09582

Gaussian Process Regression for Minimum Energy Path Optimization and Transition State Search
DOI: 10.1021/acs.jpca.9b08239

Improving Performance of the SMD Solvation Model: Bondi Radii Improve Predicted Aqueous Solvation Free Energies of Ions and pKa Values of Thiols
DOI: 10.1021/acs.jpca.9b02340

Kinetic Study of the Temperature Dependence of OH-Initiated Oxidation of n-Dodecane
DOI: 10.1021/acs.jpca.9b07704

Electronic Communication as a Transferable Property of Molecular Bridges?
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpca.9b05618


The Journal of Physical Chemistry B

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Energy Transport across Interfaces in Biomolecular Systems
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07086

Halogen Bonding beyond Crystals in Materials Science
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpcb.9b07035

Solubility of Caffeine in Supercritical CO2: A Molecular Dynamics Simulation Study
DOI: 10.1021/acs.jpcb.9b08351

Hydrogen Abstraction of Ketoprofen in the Excited Triplet State with Indole and Methylindoles
DOI: 10.1021/acs.jpcb.9b06786

Interaction and Dynamics in a Fully Biodegradable Glucose-Containing Naturally Abundant Deep Eutectic Solvent: Temperature-Dependent Time-Resolved Fluorescence Measurements
DOI: 10.1021/acs.jpcb.9b06783


The Journal of Physical Chemistry C

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Getting the Right Twist: Influence of Donor–Acceptor Dihedral Angle on Exciton Kinetics and Singlet–Triplet Gap in Deep Blue Thermally Activated Delayed Fluorescence Emitter
DOI: 10.1021/acs.jpcc.9b08269

Film Conformality and Extracted Recombination Probabilities of O Atoms during Plasma-Assisted Atomic Layer Deposition of SiO2, TiO2, Al2O3, and HfO2
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b08176

Theory of Impedance Spectroscopy for Lithium Batteries
DOI: 10.1021/acs.jpcc.9b07389

Charge Transfer during the Dissociation of H2 and the Charge State of H Atoms in Liquid Gallium
DOI: 10.1021/acs.jpcc.9b06779

Transmission Line Model for Description of the Impedance Response of Li Electrodes with Dendritic Growth
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcc.9b05887


The Journal of Physical Chemistry Letters

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Singlet Fission in Crystalline Organic Materials: Recent Insights and Future Directions
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.jpclett.9b00754

Two-Dimensional Ferroics and Multiferroics: Platforms for New Physics and Applications
DOI: 10.1021/acs.jpclett.9b01969

Ultrafast Tracking of Exciton and Charge Carrier Transport in Optoelectronic Materials on the Nanometer Scale
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpclett.9b02437

Carrier Extraction from Perovskite to Polymeric Charge Transport Layers Probed by Ultrafast Transient Absorption Spectroscopy
DOI: 10.1021/acs.jpclett.9b02502

CsPbBr3 Perovskite Nanocrystal Grown on MXene Nanosheets for Enhanced Photoelectric Detection and Photocatalytic CO2 Reduction
DOI: 10.1021/acs.jpclett.9b02605


Journal of Proteome Research

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MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics
DOI: 10.1021/acs.jproteome.9b00313

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
DOI: 10.1021/acs.jproteome.9b00500

Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model
DOI: 10.1021/acs.jproteome.9b00492

Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
DOI: 10.1021/acs.jproteome.9b00481

Vegetative Cell and Spore Proteomes of Clostridioides difficile Show Finite Differences and Reveal Potential Protein Markers
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jproteome.9b00413


Molecular Pharmaceutics

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A Human Immortalized Cell-Based Blood–Brain Barrier Triculture Model: Development and Characterization as a Promising Tool for Drug−Brain Permeability Studies
DOI: 10.1021/acs.molpharmaceut.9b00519

Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
DOI: 10.1021/acs.molpharmaceut.9b00361

Molecular Engineering of Adeno-Associated Virus Capsid Improves Its Therapeutic Gene Transfer in Murine Models of Hemophilia and Retinal Degeneration
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00959

Bioconjugation of Cyclometalated Gold(III) Lipoic Acid Fragments to Linear and Cyclic Breast Cancer Targeting Peptides
DOI: 10.1021/acs.molpharmaceut.9b00695

Deep Convolutional Generative Adversarial Network (dcGAN) Models for Screening and Design of Small Molecules Targeting Cannabinoid Receptors
DOI: 10.1021/acs.molpharmaceut.9b00500


Organic Process Research & Development

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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.9b00465

Green Chemistry Articles of Interest to the Pharmaceutical Industry
DOI: 10.1021/acs.oprd.9b00450

Mutagenic Impurities in 1-Hydroxybenzotriazole (HOBt)
DOI: 10.1021/acs.oprd.9b00376

Scalable, Economical, and Practical Synthesis of 4-(Difluoromethyl)pyridin-2-amine, a Key Intermediate for Lipid Kinase Inhibitors
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.oprd.9b00312

A Scalable Process for the Synthesis of 1,2-Dialkyldiselanes and 1-Alkaneselenols
DOI: 10.1021/acs.oprd.9b00380


Discover the Most-Read Analytical Chemistry Articles of November 2019

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in November 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Get free monthly updates on the most-read research in your field.

Read more of November’s most-read articles.


ACS Earth and Space Chemistry
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Iron Redox Chemistry and Its Environmental Impact: A Virtual Special Issue
DOI: 10.1021/acsearthspacechem.9b00282

Virtual Issue on Astrochemistry: From the Chemical Laboratory to the Stars
DOI: 10.1021/acsearthspacechem.9b00259

A High-Pressure Compound of Argon and Nickel: Noble Gas in the Earth’s Core?
DOI: 10.1021/acsearthspacechem.9b00212

Enhanced Immobilization of Arsenic from Acid Mine Drainage by Detrital Clay Minerals
DOI: 10.1021/acsearthspacechem.9b00203

Layer Charge Effects on Adsorption and Diffusion of Water and Ions in Interlayers and on External Surfaces of Montmorillonite
DOI: 10.1021/acsearthspacechem.9b00236


ACS Sensors

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Protein–Polymer Block Copolymer Thin Films for Highly Sensitive Detection of Small Proteins in Biological Fluids
DOI: 10.1021/acssensors.9b01020

Ultrasensitive Chemiluminescence Biosensor for Nuclease and Bacterial Determination Based on Hemin-Encapsulated Mesoporous Silica Nanoparticles
DOI: 10.1021/acssensors.9b01303

Amperometric Aptasensor for Amyloid-β Oligomer Detection by Optimized Stem-Loop Structures with an Adjustable Detection Range
DOI: 10.1021/acssensors.9b01630

Paper-Based Microfluidic Device (DON-Chip) for Rapid and Low-Cost Deoxynivalenol Quantification in Food, Feed, and Feed Ingredients
DOI: 10.1021/acssensors.9b01895

Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath
Open Access Through ACS AuthorChoice
DOI: 10.1021/acssensors.9b01403


Analytical Chemistry

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Deciphering Metabolic Heterogeneity by Single-Cell Analysis
DOI: 10.1021/acs.analchem.9b02410

Welcome JASMS to the ACS Measurement Science Family
DOI: 10.1021/acs.analchem.9b04705

Pacifier Biosensor: Toward Noninvasive Saliva Biomarker Monitoring
DOI: 10.1021/acs.analchem.9b03379

Versatile Electrochemiluminescence and Photoelectrochemical Detection of Glutathione Using Mn2+ Substitute Target by DNA-Walker-Induced Allosteric Switch and Signal Amplification
DOI: 10.1021/acs.analchem.9b03990

Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues
DOI: 10.1021/acs.analchem.9b03617


Chemical Research in Toxicology

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Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
DOI: 10.1021/acs.chemrestox.9b00339

Computational Investigation of Drug Phototoxicity: Photosafety Assessment, Photo-Toxophore Identification, and Machine Learning
DOI: 10.1021/acs.chemrestox.9b00338

Toxicokinetic–Toxicodynamic Modeling of the Effects of Pesticides on Growth of Rattus norvegicus
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.chemrestox.9b00294

MiR-326 Inhibits Inflammation and Promotes Autophagy in Silica-Induced Pulmonary Fibrosis through Targeting TNFSF14 and PTBP1
DOI: 10.1021/acs.chemrestox.9b00194

Methods and Challenges for Computational Data Analysis for DNA Adductomics
DOI: 10.1021/acs.chemrestox.9b00196


Environmental Science & Technology

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Plastic Teabags Release Billions of Microparticles and Nanoparticles into Tea
DOI: 10.1021/acs.est.9b02540

Environmental Science & Technology Presents the 2019 Reviewer Awards
DOI: 10.1021/acs.est.9b05993

On the Road to Paris: The Shifting Landscape of CO2 Reduction
DOI: 10.1021/acs.est.9b05909

Adaptation of Black Carbon Footprint Concept Would Accelerate Mitigation of Global Warming
DOI: 10.1021/acs.est.9b05586

Surficial Sediment from the Milwaukee River Basin to Lake Michigan
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.est.9b03850


Environmental Science & Technology Letters
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Sunlight Converts Polystyrene to Carbon Dioxide and Dissolved Organic Carbon
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.estlett.9b00532

Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.estlett.9b00582

Environmental Science & Technology Letters Presents the 2019 Excellence in Review Awards
DOI: 10.1021/acs.estlett.9b00632

Fate of Per- and Polyfluoroalkyl Ether Acids in the Total Oxidizable Precursor Assay and Implications for the Analysis of Impacted Water
DOI: 10.1021/acs.estlett.9b00525

Polyethylene Terephthalate and Polycarbonate Microplastics in Sewage Sludge Collected from the United States
DOI: 10.1021/acs.estlett.9b00601


Journal of Agriculture and Food Chemistry

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Reclaiming Phosphate from Waste Solutions with Fe(III)–Polysaccharide Hydrogel Beads for Photo-Controlled-Release Fertilizer
DOI: 10.1021/acs.jafc.9b02860

Supplementation of Sesamin Alleviates Stress-Induced Behavioral and Psychological Disorders via Reshaping the Gut Microbiota Structure
DOI: 10.1021/acs.jafc.9b03652

Discovery of Novel Isothiazole, 1,2,3-Thiadiazole, and Thiazole-Based Cinnamamides as Fungicidal Candidates
DOI: 10.1021/acs.jafc.9b03891

Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases
DOI: 10.1021/acs.jafc.9b04073

Application of a Plant Biostimulant To Improve Maize (Zea mays) Tolerance to Metolachlor
DOI: 10.1021/acs.jafc.9b04949


Journal of Proteome Research

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MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics
DOI: 10.1021/acs.jproteome.9b00313

Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
DOI: 10.1021/acs.jproteome.9b00500

Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model
DOI: 10.1021/acs.jproteome.9b00492

Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
DOI: 10.1021/acs.jproteome.9b00481

Vegetative Cell and Spore Proteomes of Clostridioides difficile Show Finite Differences and Reveal Potential Protein Markers
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jproteome.9b00413


Carbon Nanotube Sensor Detects Nitrosamines in the Air

oxic N-nitrosamine compounds have infiltrated a surprising number of products over the years, including beer, tires, and, recently, over-the-counter drugs. Formed as by-products during manufacturing, the probable human carcinogens can also contaminate the surrounding air. High levels of airborne N-nitrosamines have been found inside and around rubber plants, posing health concerns for factory workers and nearby residents. Yet detecting the offending compounds is a slow and laborious process. Now, researchers have developed a sensitive, carbon nanotube-based sensor for real-time measurement of airborne N-nitrosamines.

20191011lnp1-ndma.jpg

Detecting N-nitrosamines in air has traditionally been a multistep process: someone must first collect suspect air within solid sorbents or liquid solutions and then ship the materials to a testing facility. Then lab technicians extract or desorb the samples and analyze them for the presence of contaminants using techniques such as liquid or gas chromatography/mass spectrometry.

To shorten this process, scientists developed a sensor to detect N-nitrosamines straight from ambient air. “These sensors have low power requirements, they’re inexpensive, and they’re portable so you can bring them anywhere into the field,” says lead author Maggie He of the University of Arkansas, who developed the device with colleagues as a postdoc in Timothy M. Swager’s lab at the Massachusetts Institute of Technology.

The sensor comprises three critical components on a glass surface: cobalt(III) tetraphenylporphyrin molecules deposited onto single-walled carbon nanotubes that are stretched between gold electrodes. The porphyrin molecules selectively bind to N-nitrosamine compounds floating by, resulting in a change in resistance across the electrodes that researchers can measure to determine N-nitrosamine concentration in air.

Notably, the device showed an 18-fold selectivity for N-nitrosodimethylamine (NDMA) over other volatile organic compounds such as ethanol and water. “For nanotube-based sensors, the sensor signal interference caused by variable background humidity is a problem,” says the University of Pittsburgh’s Alexander Star, an expert in carbon nanotube-based sensing. “The selectivity achieved over other compounds, including humidity, is very impressive.”

The researchers detected NDMA, N-nitrosodiethylamine (NDEA) and N-nitrosodibutylamine (NDBA) at concentrations as low as 1 ppb. In 1998, Germany set workplace limits for the total concentration of airborne N-nitrosamines at 2.5 µg/m3 (1 µg/m3 NDMA equals 3 ppb); no such limits on N-nitrosamines have been established in the US.

The sensor also detected parts-per-billion levels of NDMA when hooked up to a commercially available sensing device, which has a pump that draws in air and a processor that sends readings in real-time to a computer or smartphone.

Although the device is designed for air sampling, He says it may be possible to use it to detect N-nitrosamine contaminants now affecting heart drugs such as valsartan and the antacid Zantac (ranitidine). She suggests potentially crushing up the pills then vaporizing them into a gas for analysis.

For now, the Swager lab is interested in using the sensor and another method developed in their lab for detecting contaminants in water, which would allow them to measure N-nitrosamines found at polluted sites around Maine as part of the MIT Superfund Research Program.

This article is reproduced with permission from C&EN (© American Chemical Society). The article was first published on October 11, 2019.

The First Fully Printed Electronics Roll Off Printers Ready to Use

Interest in printed electronics has surged in the past decade as a way to mass-produce RFID tags and sensors at a low cost. But printing digital logic devices on a substrate today involves multiple steps beyond the printer, such as rinsing or curing in an oven. Now, researchers have made the first fully printed transistors—ones that emerge from a printer with all of their components in place, ready to be used.

Work on printed circuitry typically has focused on inkjet printers, which use tiny nozzles to deposit ink droplets onto a substrate. The inks are suspensions of different materials—conductive nanoparticles, semiconducting carbon nanotubes, or insulating polymers—used to print different layers of thin-film transistors over several runs through the printer. But after printing, the process requires washing away unwanted materials and heating at high temperature to cure the insulating layer.

To get rid of those extra steps, Aaron D. Franklin, an electrical and computer engineer at Duke University, and his colleagues used a technique called aerosol jet printing. Their new process allows all of the steps to happen in place at the printer. Everything is done at temperatures less than 80 °C, which lets the researchers print transistors on paper.

Aerosol jet printing uses pressure and an inert gas to break up the ink into microscopic droplets “like aerosol hair spray,” Franklin says. “This makes it possible to print in smaller lines and to dry more rapidly because you are minimizing droplet size and the volume of background solvent.” That means less unwanted material to rinse off or evaporate outside a printer.

20191007lnp4-micro.jpg

Credit: Shiheng Lu/Duke University
A cross-section of a transistor printed with a new aerosol jet printing technique shows two electrode layers of silver nanowires (top and bottom) sandwiching an insulator layer printed with hexagonal boron nitride flakes (middle). There is no mixing of the layers, which is an issue with conventional printing methods.

The team first printed layers of carbon nanotubes on paper and plastic substrates to form the conductive channel of a transistor. Without removing the substrate from the printer, the researchers placed a few drops of toluene for 20 s on the substrate, gently warmed it at 80 °C, and blow-dried it with a nitrogen gun to remove excess material. Then they printed electrodes using water-based silver nanowire ink.

The next layer marked a key advance: printing a quality insulator film using an ink of 2-D hexagonal boron nitride (h-BN) flakes. “One of the most challenging areas for printed logic devices has been the development of a good, patterned insulator layer,” says Ioannis Kymissis, an electrical engineer at Columbia University who was not involved in the work.

Printed h-BN layers normally require baking at 180 °C for 2 h to create a smooth film with flat, well-arranged flakes that gives good insulating properties. And a critical concern is to avoid the mixing of the h-BN inks with the silver nanowire inks above and below, which would lead to defective transistors.

To overcome these problems, the Duke engineers added hydroxypropyl methylcellulose to their h-BN ink, which makes the ink thicker and keeps it from mixing with the silver nanowire layer below. The process, to their surprise, gave high-quality insulating h-BN layers that did not blend with the silver nanowires and did not need heating. The researchers believe the binder helps the microdroplets spread out and stick to the surface, laying down the flakes in a structured way as they are being printed. “This is an exciting discovery,” Franklin says.

Finally, the researchers printed the last electrode layer on top of the insulator and then tested the devices using standard current-voltage measurements. The devices maintained their performance after being bent 1,000 times.

The aerosol jet printing process isn’t fast enough for high-volume manufacturing, but it could be used to make custom, on-the-fly electronics or paper-based sensors. The method could also print biomolecules, Franklin says, to create a customized array of biosensors on an electronic bandage for monitoring a patient.

The fully printed, mechanically flexible devices show “outstanding overall performance,” Kymissis says, “and pulling all of this together makes for a significant advance in the field.”

This article is reproduced with permission from C&EN (© American Chemical Society). The article was first published on October 07, 2019.

Single-Atom Switcheroo Yields Fluorescent Dyes Activated by Visible Light

Researchers have developed a simple method for making fluorescent dyes of many colors that can be activated by visible light. The method involves switching out a single oxygen atom in existing fluorescent dyes for a sulfur atom, which makes them photoactivatable. The approach provides a new set of tools for visualizing how proteins and other molecules behave in living cells without damaging tissue.

Today’s light microscopes are so powerful that they can track molecules at nanometer-scale resolution as a cell conducts its business. Researchers want to be able to turn fluorescent dyes on and off in order to selectively light up and track specific molecules over time in living cells. But scientists have struggled to capture these close-ups because the photoactivatable dyes commonly used for labeling molecules have some major limitations: the dyes can be bulky, so they can’t label smaller molecules with good resolution, and they need to be activated with high-energy laser light. The intense illumination damages DNA and mitochondria and causes proteins to cross-link. It also bleaches the fluorescence that the dyes deliver. So dyes that can be triggered with low-power visible light would be a boon for biological imaging in living tissue.

Previous work had shown that trading the carbonyl group for a thiocarbonyl group in a dye can quench fluorescence nearby. In the new study, Han Xiao, a chemist and bioengineer at Rice University, and his team demonstrated that if the thiocarbonyl group is incorporated into the conjugated system of an ordinary, nonphotoactivatable fluorescent dye, the dye can be photo-oxidized with visible light. Xiao and his team used a one-step chemical reaction involving a thionating agent called Lawesson’s reagent to switch the carbonyl group’s oxygen to sulfur, essentially suppressing the glow.

20190927lnp2-figure3.jpg

Credit: J. Am. Chem. Soc.
A photoactivated red dye (bottom left) labels lipid droplets in a cell just like a commercial nonphotoactivatable green dye (top right). Brown shows the colocalization of the dyes (bottom right). Cell nuclei are stained blue.

Unleashing the fluorescence simply involves flashing a dye solution with low-intensity visible light of a wavelength the same or shorter than that emitted by the dye, Xiao explains. If the dye is red, for example, a red, green, or blue light would activate it. “The chemistry we are using is really simple,” Xiao says. The photoactivation requires just visible light and oxygen, which is present at sufficient levels naturally dissolved in saline buffer.

Xiao’s team used the approach to create light-activated versions of common red, green, blue, and purple dyes that can be made to target different biomolecules or parts of the cell. They used one of the dyes to visualize lipid droplets and another to mark specific sites within a protein. They also demonstrated that they could use two different dyes simultaneously to label different parts of a lipid droplet.

Luke D. Lavis, a biochemist at Janelia Research Campus, says he likes the paper because the fluorescence quenching is accomplished with substitution of a single atom, so the resulting molecule is small. Researchers could encode such a molecule into a protein that could then be made to fluoresce without using any additional reagents.

A huge variety of nonphotoactivatable dyes exist, and most of them should respond to this strategy, Xiao says. “The beauty of our chemistry is that you don’t need a really strong light source. You can use an LED you get from Amazon, and it works.”

Xiao’s team is continuing to make more dyes using the approach. They are also testing the strategy for near-infrared dyes, which can penetrate tissue more deeply.

This article is reproduced with permission from C&EN (© American Chemical Society). The article was first published on September 30, 2019.