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ChemRxiv celebrates its fifth anniversary

This August, ChemRxiv celebrates its fifth anniversary. Launched in 2017, ChemRxiv has helped thousands of authors post more than 14,000 unique preprints across all fields of chemistry. These preprints have been viewed and downloaded nearly 38 million times. Additionally, many of these preprints have been peer-reviewed and published in top journals such as the Journal of the American Chemical Society, Angewandte Chemie, Chemical Science, Nature, Science, and more!

As part of our celebration, we published an editorial that reflects on the past five years and takes a look at what is next for ChemRxiv. We also interviewed the author of a recent preprint to learn more about their experience posting preprints and how ChemRxiv fits into their publishing goals.

This interview with Dr. Feihu Li of Nanjing University of Information Science and Technology relates to the preprint “Arsenic(V) Immobilization in Fly Ash and Lead-Zinc Mine Tailing-based Geopolymer: Performance and Mechanism Insight,” posted on February 4, 2022 and later published in the journal Chemosphere. The other authors on this preprint are Alseny Bah, Jie Jin, and Andrea O. Ramos, all from Nanjing University of Information Science and Technology.

Why did you decide to submit this recent preprint?

Compared to peer review and formal publication, which usually takes more than a few months, the preprint service allows for faster sharing of our lab’s research progress with national and international peers in about a week.

Did you have any prior experience with preprints?

Yes. I am used to submitting our manuscripts to the ChemRxiv preprint service prior to formal submission to a journal.

Can you give us a brief summary of the research shared in your preprint?

In this paper, we have developed a geopolymer by using fly ash and lead-zinc mine tailing as raw materials. The geopolymer not only can stabilize exogenous arsenic contaminants in the long term, but also has a strong compressive strength. Therefore, it can be used as a greener and low-carbon building material to substitute some conventional building materials with a high carbon footprint.

What feedback have you received about your preprint (or past preprints)?

No feedback has been received on this preprint yet. However, I note that a previously submitted ChemRxiv preprint was cited many times by international peers in formally published papers.

If you are attending the ACS Fall Meeting in Chicago, there will be a brief presentation from the ChemRxiv team from 1:00 to 1:30 PM CDT on Monday, August 22 in the ACS Theater in the exhibit hall of the McCormick Place Convention Center. We would be happy to answer your questions and learn about your experience with preprints.

ChemRxiv now accepts reviews

Authors using ChemRxiv can submit their research findings for rapid posting on the web and sharing with scientists and colleagues before formal peer review. We’re pleased to announce that authors can now send preprints of review articles to ChemRxiv! In this phase of expanding our scope, ChemRxiv will now accept reviews that provide well-sourced context for previous research from multiple sources. ChemRxiv will still not accept short format letters/commentaries/opinions or purely hypothetical works. For more information, please see our submission FAQs or contact us at curator@chemrxiv.org.

To support this change, you will now be asked to select a Content Type during submission, choosing from “working paper” (for any preprint containing new research results) or “review.” 

Submit your reviews today at ChemRxiv.org

ChemRxiv expands Direct Journal Transfer
Direct Journal Transfer is a free feature of ChemRxiv that helps authors submit their posted preprints from ChemRxiv to established journals for editorial consideration and peer review. This feature, which is available through the ChemRxiv author dashboard, enables direct submission to journals published by the American Chemical Society (ACS), the Royal Society of Chemistry (RSC), the German Chemical Society (GDCh), including ChemPubSoc Europe (CPSE) journals. 

We are expanding the program to include new journals and publishers, and you can now stay up to date on all the available destination journals on our Direct Journal Transfer webpage.

ChemRxiv expands Direct Journal Transfer ​​

 

ChemRxiv site accessibility
As part of our ongoing goal of helping share the latest chemistry research as broadly as possible, the ChemRxiv site recently underwent a thorough accessibility audit. We made a number of small changes (many undetectable to most users), and the site now adheres to Web Content Accessibility Guidelines (WCAG) 2.1 AA standards, a high bar for online content providers. You can read more about accessibility on ChemRxiv here.

Recent most-read preprints from ChemRxiv
Here are the most downloaded preprints from January 2022. Thank you to all the authors and readers who make ChemRxiv the premier preprint server for the global chemistry community!

December 2021 News and Updates from ChemRxiv

As 2021 draws to a close, we wanted to provide some updates about ChemRxiv and wish you all a fabulous finish to the year! Please note that staff holidays over the last two weeks of the year may slightly increase processing times for new submissions, so we ask for your patience if you are submitting a preprint in late December.

Find out more about linking to your peer-reviewed version of record

Did you know that ChemRxiv automatically adds a link to the related journal article within a few weeks of journal publication? The timing depends on when the journal posts its files to Crossref, allowing ChemRxiv to check and make matches between preprints and published articles.

You can also request a link to the published version of your paper if you notice that your preprint hasn’t been properly matched to the published version. To do this, visit the latest version of the content in your author dashboard, and select “Submit version of record”. You will then be prompted to provide the DOI of your published work. Before you submit the DOI, please select “Check your DOI” and make sure that the metadata pulled from Crossref is correct. If so, click “Submit”. Once you have submitted the DOI, it will be reviewed by an administrator before being posted on your content page. You will receive an email notifying you of the administrator’s decision.

To view the related video guide, as well as other videos on submission and revision of your preprint, creating an ORCID, and direct journal transfer, please visit the “How To Submit“ section of ChemRxiv.  

ChemRxiv surpassed the milestone of 10,000 preprints posted!

The entire ChemRxiv team would like to thank our authors for their contributions over the last four years. Your preprints have been viewed and downloaded more than 28 million times, an indication of their benefit to the chemistry community and beyond. We are deeply grateful for your support and appreciate your willingness to share your research with the world via ChemRxiv!

The 10,000th preprint posted to ChemRxiv was “Single-Macromolecular Level Imaging of a Hydrogel Structure,” authored by researchers from Hokkaido University and Tohoku University: Ryuji Kiyama, Takayuki Nonoyama, Sedlacik Tomas, Hiroshi Jinnai, and Jian Ping Gong.

Read a brief interview with Dr. Jian Ping Gong of Hokkaido University, the PI of the group that posted this research, to find out more about their recent preprint.

ChemRxiv preprints from Nobel Laureates 

The Nobel Prize in Chemistry 2021 was awarded jointly to Drs. Benjamin List and David W. C. MacMillan for their work in the development of asymmetric organocatalysis, a method that uses small organic molecules as catalysts instead of enzymes or metals. This innovation in molecular construction has led to catalysts that are less expensive and more environmentally friendly, while also opening up new pathways in pharmaceutical research.

Please check out some examples of the research from this year’s Nobel Laureates that has been posted on ChemRxiv:

Share your research with the global community of scientists at ChemRxiv.org!

ChemRxiv Surpasses 10,000 Preprints Posted

On September 21, 2021, ChemRxiv surpassed the milestone of 10,000 preprints posted to ChemRxiv.org! The entire ChemRxiv team would like to thank our authors for their contributions over the last four years. These preprints have been viewed and downloaded more than 28 million times, an indication of their benefit to the chemistry community and beyond. We are deeply grateful for your support and appreciate your willingness to share your research with the world via ChemRxiv!

The 10,000th preprint posted to ChemRxiv wasSingle-Macromolecular Level Imaging of a Hydrogel Structure,” authored by researchers from Hokkaido University and Tohoku University: Ryuji Kiyama, Takayuki Nonoyama, Sedlacik Tomas, Hiroshi Jinnai, and Jian Ping Gong. 

I sat down with Dr. Jian Ping Gong of Hokkaido University, the PI of the group that posted this research, to find out more about their recent preprint:

Why did you decide to submit this recent preprint?

This work is going to be submitted to a journal soon. However, we have another paper using the technique invented in this work that was accepted recently and going to be published before this paper. We decided to submit this preprint so that it can be cited properly.

Did you have any prior experience with preprints?

Yes, we have submitted preprints before, including these two to ChemRxiv:

Can you give us a brief summary of the research shared in your preprint?

Observation of the synthetic polymer network structure of hydrogels in real space remains a challenge. Herein, for the first time, we developed a novel mineral-staining method for transmission electron microscopy observation to visualise the polyelectrolyte hydrogel network in its unperturbed conformation with nanometre resolution. The molecular structure on surface and bulk hydrogels exhibited significant structural features that provide insights regarding the friction and fracture of polymeric hydrogel materials. 

What feedback have you received about your preprint (or past preprints)?

We received an invitation to submit our work to a journal.

What other research are you and your group doing?

Our group is working on molecular design, synthesis and understanding of functional hydrogels, with a large effort on tough gels including double network hydrogels. We also collaborate with medical doctors for biological application of the hydrogels. Please see our lab website for more information.

 Share your research with the global community of scientists at ChemRxiv.org

Four Years, 9,700 Preprints, 28 Million Views and Downloads on ChemRxiv

ChemRxiv was first introduced in August 2017 as the premier preprint server for the global chemistry community. Authors using ChemRxiv can submit their research findings for rapid posting on the web and sharing with scientists and colleagues before formal peer review. The first preprint submitted and posted was Excitonics: A universal set of binary gates for molecular exciton processing and signaling. This preprint went on to be peer-reviewed and published in ACS Nano.

In March 2018, the American Chemical Society, the German Chemical Society, and the Royal Society of Chemistry announced a partnership to manage ChemRxiv collaboratively. In August 2019, the Chinese Chemical Society and the Chemical Society of Japan joined the partnership to broaden ChemRxiv’s thriving global presence as a preprint server driven by the chemistry research community.

ChemRxiv: Highlights from the First Four Years

Today, ChemRxiv features nearly 10,000 preprints from authors in 100 countries that have been viewed and downloaded more than 28 million times. Additionally, almost half of these preprints have been peer-reviewed and published in top journals such as the Journal of the American Chemical Society, Angewandte Chemie, Chemical Science, Nature, Science, and more!

Here are the 10 Most Viewed Preprints Posted to ChemRxiv:

COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism
Liu Wenzhong, Li Hualan
***
Repurposing Therapeutics for COVID-19: Supercomputer-Based Docking to the SARS-CoV-2 Viral Spike Protein and Viral Spike Protein-Human ACE2 Interface
Micholas Smith, Jeremy C. Smith
***
N-acetyl cysteine: A tool to perturb SARS-CoV-2 spike protein conformation
Utsab Debnath, Amrita Mitra, Varun Dewaker, Yenamandra S. Prabhakar, Raghu Tadala, Kiran Krishnan, Padmakar Wagh, Umashankar Velusamy, Chandru Subramani, Shubhra Agarwal, Sudhanshu Vrati, Aastha Baliyan, Anura V Kurpad, Parthasarathi Bhattacharyya, Amit Mandal
***
The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination
Christopher G. Jones, Michael W. Martynowycz, Johan Hattne, Tyler J. Fulton, Brian M. Stoltz, Jose A. Rodriguez, Hosea Nelson, Tamir Gonen
***
Comparing the Respirable Aerosol Concentrations and Particle Size Distributions Generated by Singing, Speaking and Breathing
Florence K. A. Gregson, Natalie A. Watson, Christopher M. Orton, Allen E. Haddrell, Lauren P. McCarthy, Thomas J. R. Finnie, Nick Gent, Gavin C. Donaldson, Pallav L. Shah, James D.Calder, Bryan R. Bzdek, Declan Costello, Jonathan Reid
***
Potential Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 606 Million Compounds
André Fischer, Manuel Sellner, Santhosh Neranjan, Markus A. Lill, Martin Smieško
***
Identification of Compounds from Nigella Sativa as New Potential Inhibitors of 2019 Novel Coronavirus (Covid-19): Molecular Docking Study
Salim Bouchentouf, Noureddine Missoum
***
A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry
Mohamed El-Tholoth, Haim H. Bau, Jinzhao Song
***
Tripartite combination of potential pandemic mitigation agents: Vitamin D, Quercetin, and Estradiol manifest properties of candidate medicinal agents for mitigation of the severity of pandemic COVID-19 defined by genomics-guided tracing of SARS-CoV-2 targets in human cells.
Gennadi Glinsky
***
Whole Genome Sequence Analysis and Homology Modelling of a 3C Like Peptidase and a Non-Structural Protein 3 of the SARS-CoV-2 Shows Protein Ligand Interaction with an Aza-Peptide and a Noncovalent Lead Inhibitor with Possible Antiviral Properties
Arun Shanker, Divya Bhanu, Anjani Alluri, Samriddhi Gupta

Share your research with the global community of scientists at ChemRxiv.org

ChemRxiv Moves to Cambridge University Press’ Open Engage Platform

Starting on June 17, 2021, ChemRxiv, the premier preprint server for the chemical sciences, will be hosted through the Cambridge Open Engage platform. Everyone on the ChemRxiv team is excited about the new, improved experience for ChemRxiv authors and readers, designed to complement the high-quality content, policies, and features that ChemRxiv offers today.

On the new ChemRxiv site, which will remain at chemrxiv.org, authors posting preprints will benefit from an improved experience while still having access to all key existing features, such as links to the final version of record, direct transfer to a growing list of journals, and usage metrics for posted preprints. There will also be enhancements to ChemRxiv’s publishing platform, including an improved author dashboard where you can view the status of your content uploads, easily upload new versions of your preprints, and see your preprint stats at a glance. ChemRxiv readers will also benefit from updated browsing and searching interfaces for finding relevant content, without having to log in, and the website will feature expanded policy pages and information.

The new platform uses ORCID, the unique identifier for researchers, for its login process. Starting June 17, all submitting ChemRxiv authors will need to have a valid ORCID in order to log in and submit preprints for consideration. In addition, we will match your prior preprints using the ORCID listed when they were originally submitted, and those preprints will be available on your dashboard when you log in with your ORCID. If you are a ChemRxiv author and do not currently have an ORCID, you can sign up for one on the ORCID website. Registering is free and only takes a few moments.

ChemRxiv will continue to be co-owned and co-managed by the following organizations:

More information about this move along with answers to some common questions for authors and researchers can be found on this page. The ChemRxiv support team is always available for questions at support@chemrxiv.org, or on Twitter @ChemRxiv.