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3 Reasons to Direct Transfer Your Manuscript from bioRxiv to an ACS Journal

The Editors and staff at ACS Publications, a nonprofit publisher and division of the American Chemical Society, are proud to announce that 12 of the peer-reviewed journals in our biological portfolio are accepting direct transfers of manuscripts and metadata from bioRxiv as of Monday, June 6, 2022.

If you already publish your findings in our journals, we hope this will make that process even easier for you! If you haven’t published in an ACS biological journal recently—or ever—we bet you’ve read one of our articles on PubMed Central or Google Scholar, and hope you’ll read on to learn more.


3 Reasons to Publish Your Biological Paper in an ACS Publications Journal

1. ACS Publications is a nonprofit society publisher and a division of the American Chemical Society.

ACS Publications is an experienced publisher with a focus on serving researchers and the scientific community. We do this by:

  • Enlisting practicing researchers from prominent institutions around the world to serve as Editors-in-Chief and other members of our journals’ editorial teams.
  • Employing a high-quality peer-review process developed over more than 140 years of publishing respected scholarly journals.
  • Expediting manuscript processing to deliver decisions and get papers published as quickly as possible.


2. ACS has more than 60 years of experience publishing high-quality biological journals.

ACS expanded our engagement with the global community of scientific researchers more than a half century ago. Now we have more than a dozen core biological journals as well as more than 20 multidisciplinary journals and those focused on branches of chemistry that also publish articles about biological research.


3. ACS offers authors a variety of publishing options.

Authors who publish with ACS can choose to publish in a hybrid, Plan S-compliant Transformative Journal or in a fully open access journal.

  • Most ACS journals are Transformative Journals, which offer a choice of publishing under the traditional subscription model or under the newer open access model:
    • It’s free to submit and free to publish in an ACS Transformative Journal under the traditional subscription model. That means no author charges, page charges, processing charges or color charges.
    • Once an article is accepted for publication in an ACS Transformative Journal, authors who want to make their article open access—or are required to by their funders—can do so by paying an article publishing charge (APC).
  • ACS also has 12 fully open access journals, including ACS Bio & Med Chem Au, which serves the biological research community. Publishing in these journals also requires paying an APC after article acceptance.


Get to Know ACS Publications’ Biological Journals

The 12 journals listed below began accepting direct transfers of manuscripts and metadata from bioRxiv on Monday, June 6, 2022. Read on to learn more about these journals or visit pubs.acs.org to learn about all the full portfolio of ACS journals.

Journal of Medicinal Chemistry
In publication since 1959
Findings on the relationship between molecular structure and biological activity or mode of action in drug discovery and development.
Impact Factor 2020: 7.446 | Citations 2020: 85,946| CiteScore 2020: 10.6
If you have questions about this journal, please send them to jmc@jmedchem.acs.org.

In publication since 1962.
Exceptional, rigorous, high-impact interdisciplinary research articles across all of biological chemistry.
Impact Factor 2020: 3.162 | Citations 2020: 76,745| CiteScore 2020: 5.5
If you have questions about this journal, please send them to eic@biochem.acs.org.

Journal of Natural Products
In publication since 1979
Reports on natural products related to the chemistry or biochemistry of naturally occurring compounds or the biology of their living systems and environments.
Impact Factor 2020: 4.050 | Citations 2020: 32,074| CiteScore 2020: 6.5
If you have questions about this journal, please send them to proteau-office@jnp.org.

Bioconjugate Chemistry
In publication since 1990
Research articles on all aspects of bioconjugates, including the preparation, properties and applications of biomolecular conjugates.
Impact Factor 2020: 4.774 | Citations 2020: 18,580| CiteScore 2020: 8.1
If you have questions about this journal, please send them to eic@bioconj.acs.org.

Molecular Pharmaceutics
In publication since 2004
Findings that contribute to the molecular mechanistic understanding of drug delivery and drug delivery systems.
Impact Factor 2020: 4.939 | Citations 2020: 22,570| CiteScore 2020: 8.1
If you have questions about this journal, please send them to taylor-office@mp.acs.org.

ACS Chemical Biology
In publication since 2006
Reports of research on cellular processes using in vitro, cellular or whole organism studies at the chemical and biological interface.
Impact Factor 2020: 5.100 | Citations 2020: 16,023| CiteScore 2020: 7.6
If you have questions about this journal, please send them to ed-office@chembio.acs.org.

ACS Chemical Neuroscience
In publication since 2010
Chemical, quantitative biological, biophysical, and bioengineering research reports on the nervous system and neurological disorders.
Impact Factor 2020: 4.418 | Citations 2020: 10,120| CiteScore 2020: 6.5
If you have questions about this journal, please send them to eic@chemneuro.acs.org.

ACS Medicinal Chemistry Letters
In publication since 2010
New findings in drug discovery, compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology.
Impact Factor 2020: 4.345 | Citations 2020: 8,201| CiteScore 2020: 5.8
If you have questions about this journal, please send them to eic@medchemlett.acs.org.

ACS Synthetic Biology
In publication since 2012
Reports on integrative, molecular approaches to the understanding of the organization and function of cells, tissues, and organisms in systems.
Impact Factor 2020: 5.110 | Citations 2020: 7,500| CiteScore 2020: 7.9
If you have questions about this journal, please send them to eic@synthbiol.acs.org.

ACS Infectious Diseases
In publication since 2015
Highlights the role of chemistry in the multidisciplinary and collaborative field of infectious diseases.
Impact Factor 2020: 5.084 | Citations 2020: 3,865| CiteScore 2020: 6
If you have questions about this journal, please send them to eic@id.acs.org.

ACS Pharmacology & Translational Science
In publication since 2018
A biomedical journal reporting advances across the molecular and biological sciences—from basic and preclinical studies to clinical trials.
If you have questions about this journal, please send them to eic@ptsci.acs.org.

ACS Bio & Med Chem Au
In publication since 2021
Biological and medicinal chemistry covering the chemical, physical, biological, mechanistic, and structural basis of biological function.
If you have questions about this journal, please send them to booker-office@biomedchemau.acs.org.

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Call for Papers: Data Science for Advancing Environmental Science, Engineering, and Technology

There are many environmentally relevant research areas where advances in data science including machine learning (ML) and artificial intelligence (AI) have been applied to large datasets to better decipher the complex relationships between system variables and system behaviors, leading to new insights on solution development. 

This joint call for papers by Environmental Science & Technology and Environmental Science & Technology Letters seeks contributions on ML and AI research studies in environmental areas that demonstrate the great potential of these approaches to improve, for example, our understanding of natural and engineered environmental systems, towards maintaining a healthy ecosystem, and/or building a circular economy.

Papers are desired that include either novel applications of data science/ML methodologies and approaches adapted for use in environmental datasets, or address knowledge gaps in an important environmental science and technology that were not approachable using standard analysis tools.

Submissions to the Special Issue should demonstrate the “value added” of taking a ML or AI approach over existing approaches.  Submissions should also ensure that the datasets are large and complex enough that ML approaches are necessary and robust, and researchers must go beyond the “black box” of simple agnostic applications of existing algorithms to determine the “best one”. Papers should ideally also allow insights into mechanistic underpinnings of the system being investigated.

To serve as model examples of ML and AI analyses on complex environmental datasets, papers must facilitate reproducibility by adhering to FAIR data principles and demonstrate computational rigor (e.g., discuss model assumptions/limitations, data considerations, cross validation, model performance), and provide ML and AI models and datasets to readers through publicly available data repositories.

Submit your manuscript


Greg Lowry, Executive Editor, Environmental Science & Technology

Alexandria Boehm, Associate Editor, Environmental Science & Technology and Environmental Science & Technology Letters

Bryan W. Brooks, Editor-in-Chief, Environmental Science & Technology Letters

Pablo Gago-Ferrero, Topic Editor, Environmental Science & Technology

Guibin Jiang, Associate Editor, Environmental Science & Technology

Gerrad Jones, Topic Editor, Environmental Science & Technology

Qian Liu, Guest Editor

Z. Jason Ren, Topic Editor, Environmental Science & Technology and Environmental Science & Technology Letters

Shuxiao Wang, Associate Editor, Environmental Science & Technology  and Environmental Science & Technology Letters

Julie Zimmerman, Editor-in-Chief, Environmental Science & Technology


Author Instructions:

To submit your manuscript, please visit the Environmental Science & Technology or Environmental Science & Technology Letters website. Please follow the normal procedures for manuscript submission and when in the ACS Paragon Plus submission site, select the special issue of Data Science for Advancing Environmental Science, Engineering, and Technology.” All manuscripts will undergo rigorous peer review. For additional submission instructions, please see the Environmental Science & Technology Author Guidelines or the Environmental Science & Technology Letters Author Guidelines.

The deadline for submissions is January 12, 2023.

ACS article PDFs now include recommended articles

ACS Publications has introduced an enhancement to the PDF version of ACS journal articles that will assist with your browsing and research discovery. We now feature recommended articles at the end of journal article PDFs that will provide you a link to related research. This serves as a complement to the recommended article list that has appeared on the HTML version of our research articles.

The recommended articles will be located at the end of the PDF as shown here. Read on to find out more:

How many recommended articles will be on a PDF?
Each article can have four recommendations, where space allows. 

How are the article recommendations generated?
Article recommendations are powered by AI, based on a combination of content analysis and viewing patterns. These recommendations will change over time, based on changing viewing patterns of that article and any related ones.

Which journal article PDFs have this enhancement?
ACS journal research articles, rapid communications, and review articles published from December 2021 to the present are eligible for recommendations.  Recommendations will be placed only if there is space on the last page of the PDF. 

Where can I see this feature?
Check out this research article and you will see a list of recommended articles at the end of the PDF.

ChemRxiv to Receive Increased Support Through New Chinese & Japanese Partnerships

The American Chemical Society, the Gesellschaft Deutscher Chemiker (German Chemical Society) and the Royal Society of Chemistry announce their partnership with the Chinese Chemical Society and the Chemical Society of Japan as co-owners to support the strategic and financial development of ChemRxiv, the premier preprint server for the global chemistry community.

Through the establishment of this strong international alliance, ChemRxiv is supported, developed and led by the Societies representing the global chemistry research community. Close collaboration between the five Societies ensures the sustainability of this service and presents a clear path to broader engagement with authors and readers of the service.

“ChemRxiv is such a new project in the field of chemistry to enable scientific research to be quickly shared around the world,” says Jiannian Yao, Ph.D., president of the Chinese Chemical Society. “We are delighted to join the board and provide strong representation from China, working with our partners to better serve the global chemical community.”

“We at the Chemical Society of Japan are honored to support this endeavor. ChemRxiv offers scientists a path to immediately disseminate and share their new research findings openly with readers around the globe,” remarks Maki Kawai, Ph.D., president of the Chemical Society of Japan.

Authors working across all fields of chemistry can post their research findings to the server ahead of formal peer review and publication. The service is free of charge, features a streamlined portal for direct and easy submission and supports a wide variety of file formats. ChemRxiv submission includes a triage process that checks for plagiarism and scientific integrity, while retaining its rapid posting time of less than two business days.

Direct Journal Transfer, a recently introduced feature, enables easy submission to journals published by the American Chemical Society, the Royal Society of Chemistry and the Gesellschaft Deutscher Chemiker, including ChemPubSoc Europe journals. With this new agreement, journals published by the Chinese Chemical Society, including its new flagship journal CCS Chemistry, and the Chemical Society of Japan will be added in the near future.

“With the backing of the Chinese Chemical Society and the Chemical Society of Japan, we can ensure that ChemRxiv is truly the global preprint server for chemistry,” says Emma Wilson, Ph.D., chair of the ChemRxiv Governing Board. “It’s an important service for researchers across the globe, representing all the chemical sciences, and cementing a partnership between five major chemical societies makes certain that our international community is at the heart of ChemRxiv.”

To learn more about ChemRxiv or to share your research, visit ChemRxiv.org.

Meet ACS Biomaterials Science & Engineering’s Early Career Board Members

ACS Biomaterials Science & Engineering has announced the members of its inaugural Early Career Board. This initiative will provide young investigators with guidance and insight into the editorial process as they pursue their independent research careers. Over the course of a three-year term, the journal will foster professional mentoring relationships between its established Editorial Advisory Board members and Editors and the “in-training” Early Career Board.

Learn More About the New ACS Biomaterials Science & Engineering Early Career Board Members:

Abigail S. Knight

Dr. Abigial S. Knight grew up in Charlottesville, Virginia, before attending the University of North Carolina, Chapel Hill, as an undergraduate student.  There she completed a major in chemistry with minors in mathematics and biology and pursued bioorganic chemistry research in the lab of Marcey Waters developing ligands for RNA and DNA structures. She pursued her Ph.D. in the chemical biology program at the University of California, Berkeley, in the lab of Matthew Francis.

During graduate school she developed a combinatorial screening platform for identifying peptoid ligands with the ability to selectively bind metal ions of interest in various applications. Her postdoctoral work at the University of California, Santa Barbara, with Craig Hawker has focused on developing polymeric materials with unique architectures and both biological and materials applications. In the summer of 2018, Knight returned to the University of North Carolina, Chapel Hill, to join the Chemistry Department as an Assistant Professor with research developing materials with the functionality of biological molecules and physical properties of synthetic polymers.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: The most rewarding moment in my career so far has been the last few months of starting as an assistant professor. I have always loved working with students, and in the past few months that has been a much more significant part of my job description. Three undergraduate students have already joined my research group, and scientific discussions with them and prospective graduate students have been really exciting.

Ann-Christin Pöppler

Dr. Ann-Christin Pöppler is an analytical chemist with a focus on NMR spectroscopy and complementary techniques. She conducted research in NMR spectroscopy of organometallic compounds in solution and in stretched polymer gels during her Ph.D. at the University of Goettingen, Germany, with Professor D. Stalke and Dr. M. John. Then she was introduced to the world of solid-state NMR of small molecules and to XRD and computational methods through her postdoctoral experiences.

She was based first at the Max-Planck-Institute for Biophysical Chemistry in Göttingen with Professor A. Lange and then at the University of Warwick, U.K., with Professor S.P. Brown. In her current position as a junior professor at the University of Wuerzburg, Germany, she wants to use as well as expand the versatile NMR toolbox to look at polymeric drug delivery systems both from the solid-state and solution point of view, with the aim of gaining an increased understanding of the structure and assembly of these complex host-guest systems.

Apart from sitting at the spectrometer, Pöppler enjoys teaching and training of students both in the lecture hall as well as in the workgroup and is also happy to be part of the SMASH small molecule NMR conference Organizing Committee since the end of 2017.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: When the students said that they learned lots in the lecture, on one hand; and the moment when I understand a chemical system better based on our data, on the other hand.

Behzad Babaei

Dr. Behzad Babaei got his Ph.D. at Washington University in St. Louis under the supervision of Professor Guy Genin, who co-directs the National Science Foundation’s Science and Technology Center for Engineering Mechaobiology, and Professor Stavros Thomopoulos, who directs the Carroll Laboratories for Orthopedic Research at Columbia University. He is currently doing postdoctoral training at Neuroscience Research Australia, under the supervision of Professor Lynne Bilston.

His first area of focus is on the problem of how mechanical regulation of cell and extracellular matrix mechanics drives both physiological processes, such as wound healing and development, and pathological processes such as fibrosis. Key open questions are how the detailed relationship between mechanics and biological processes such as growth, remodeling, and repair are regulated and inter-related.

The second area of focus involves modeling wave propagation in viscoelastic media for validation of anisotropic magnetic resonance elastography methods. This work would enable physicians to non-invasively measure tissue biomechanical changes associated with early onset of fibrosis of the liver, lungs, heart, and kidney, and with the early onset of cancer in these soft tissues as well as the brain, breast, and bladder.

The third area of focus relates to tissue engineering. A major limitation of many tissue engineering applications and of all existing artificial graft technologies is scarring. By optimizing synthetic grafts to match the anisotropic and viscoelastic properties of the underlying tissues, he aims to transform reconstructive surgery.

Q: What do you see as the most exciting area of biomaterials research?
A: The most exciting area of biomaterial research for me is synthesizing a biomaterial which is mechanically (considering its anisotropic, viscoelastic and nonlinear properties) tunable.

Boyang Zhang

Dr. Boyang Zhang is an Assistant Professor in the Department of Chemical Engineering at McMaster University. Previously, Zhang was a Banting Fellow at the University of Toronto and a co-founder of a start-up company TARA Biosystems, where he developed the manufacturing process of BiowireTM plates for cardiotoxicity screening. Zhang obtained a Ph.D. in chemical engineering and applied chemistry from the University of Toronto in 2016 and B.S. in chemical and biomolecular engineering from Georgia Institute of Technology in 2010. In his undergraduate study, Dr. Zhang was trained in microfluidics under the supervision of Dr. Hang Lu at Georgia Tech.

Later, he pursued a Ph.D. in cardiac tissue engineering under the supervision of Dr. Milica Radisic. Zhang developed the AngioChip technology, which is a microfabricated implantable vascular scaffold. AngioChip was grounded in polymer chemistry and processing and enabled the creation of functional, vascularized heart and liver tissue models for organ-on-a-chip engineering in drug discovery, and tissue implantation in regenerative medicine. His research interest lies in the innovation of advanced biofabrication techniques integrated with insight from developmental biology to develop advanced in vitro tissue models for drug discovery and innovative strategies in guided tissue assembly for tissue regeneration.

Q: What do you see as the most exciting area of biomaterials research?
A: I am excited about the trend that biomaterials are becoming smarter. Our tissues and organs are dynamic, so should scaffolds and biomaterials. We hope to develop smart biomaterials that are not merely viewed as static skeletons but could structurally transform to guide tissue assembly over multiple length and time scale.

Catherine Fromen

Dr. Catherine Fromen is an Assistant Professor of Chemical and Biomolecular Engineering at the University of Delaware. She received her B.S. in chemical engineering in 2009 from the University of Rochester and her Ph.D. in chemical engineering from North Carolina State University in 2014, working with Dr. Joseph DeSimone at the University of North Carolina at Chapel Hill. After completing her postdoctoral studies at the University of Michigan as a University of Michigan’s President’s Postdoctoral Fellow, she joined the University of Delaware in 2017. Among other awards, Fromen is the recipient of the University of Michigan’s Outstanding Postdoctoral Fellow Award and the Shelby A. Miller Prize. Fromen’s graduate and postdoctoral training focused on engineering interfacial particle-cell interactions to improve nanoparticle therapeutics.

At the University of Delaware, the Fromen Research Group leverages these particle-cell interactions to study pulmonary drug delivery. The group applies engineering fundamentals, innovative tools, and current mucosal immunology to design therapeutic pulmonary aerosols and develop new analytical approaches to improve understanding of inhaled drug delivery. The group’s major research areas are: 1) leveraging 3D printing to advance in vitro tools for pulmonary drug delivery testing, 2) using engineered particles to probe lung biology and immune function, and 3) engineering novel therapeutics for controlled immune stimulation in the lung. Through all of these research areas, Fromen’s research group seeks to improve treatment options for patients with lung diseases.

Q: Who has been the most important mentor in your career?
A: The most important mentor in my career is my graduate advisor, Joe DeSimone. As an early graduate student, Joe would introduce me by saying, “this is Cathy Fromen, she wants to be a professor,” despite my repeated insistence that I was going into industry for a “real job”. He clearly saw potential in me, even when I wasn’t sure of it myself. Then and now, Joe has been an unrelenting advocate for me, supporting my growth as a researcher, professor, and human being. The opportunities and inspirations that he has catalyzed for me have been immeasurable and has set the bar for what mentorship should be. As I begin my own group, I find myself spouting many ingrained Joe-isms and hope to live up to his high standard of leadership to “represent the family well”.

Chengpeng Chen

Dr. Chengpeng Chen received his Ph.D. degree in analytical chemistry under the guidance of Dr. Dana M. Spence at Michigan State University. After that, he joined the Department of Chemistry at Saint Louis University as a research/teaching postdoctoral fellow with his Advisor, Dr. R. Scott Marti.

In August of 2018, Chen moved to the University of Maryland Baltimore County, as an assistant professor in the Department of Chemistry and Biochemistry.

Chen’s research focuses on 3D cell culture in microfluidic devices. Scaffolds such as electrospun fibers and hydrogel are widely used in his lab.

He is also interested in developing new 3D printing protocols to create biomimic fluidic devices. As an analytical chemist, another research focus of his is in situ and real-time quantitation.

Christopher M. Madl

Dr.  Christopher Madl is a Postdoctoral Fellow in Professor Helen Blau’s group in the Baxter Laboratory for Stem Cell Biology at Stanford Medical School.  His research focuses on the development of novel hydrogel platforms to study mechanosensing in skeletal muscle stem cells.  Madl completed his Ph.D. in bioengineering at Stanford University in 2017, working with Professor Sarah Heilshorn to engineer protein-based biomaterials to expand and differentiate neural stem cells.  He previously completed a M.S. in engineering sciences and a B.A. in engineering sciences and chemistry at Harvard University, both in 2012.  Madl’s research broadly focuses on the development of biomaterials to study and direct stem cell fate for applications in regenerative medicine and tissue engineering.  He is particularly interested in the study of dynamic materials systems that recapitulate the temporal changes occurring naturally in the cellular microenvironment.  These include both cell-responsive materials, which were a focus of his graduate work, as well as materials that enable real-time, user-directed changes in the cellular microenvironment, which are the subject of his present work.  Madl intends to become an independent investigator, directing a laboratory at the interface of materials science and stem cell biology.

Q: What do you see as the most exciting areas of biomaterials research?
A:  I am most excited by recent efforts to recapitulate the complex spatiotemporal aspects of the native extracellular matrix in engineered systems.  Advancements in polymer chemistry, molecular biology, and materials fabrication techniques are beginning to enable the production of engineered matrices that present complex biochemical and mechanical signals and respond to cell-mediated and user-directed inputs.  Such materials will find applications in traditional tissue engineering approaches as well as drug screening platforms for personalized medicine.

Christopher V. Synatschke

Dr. Christopher V. Synatschke trained at the University of Bayreuth, Germany as a synthetic polymer chemist and continued with his Ph.D. under the supervision of Professor Axel H.E. Müller on polyelectrolyte nanostructures for therapeutic applications.

During this time, he had the opportunity to work as a visiting scientist in research groups at the University of New South Wales, Australia, and the University of Tokyo, Japan. Then in 2014, he joined the group of Professor Samuel Stupp at Northwestern University as an Alexander von Humboldt Postdoctoral Fellow. This gave him the opportunity to work in a highly interdisciplinary team with a focus on supramolecular instead of “conventional” polymers. In this role, he was introduced to the field of regenerative medicine.

In 2017, he joined the team of Professor Tanja Weil at the Max Planck Institute for Polymer Research, Germany, where he now pursues his research on biomaterials as a group leader.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: I have had the honor of mentoring several bright, young students as part of my own scientific career. The times when motivated students engage in new ideas and challenge me during scientific discussions is the most rewarding part of my work.

Erica B. Peters

Dr. Erica Brown Peters is a Postdoctoral Research Fellow at the University of North Carolina’s Center for Nanotechnology in Drug Delivery. She is working to develop a noninvasive approach to alleviate plaque burden—the major underlying cause of cardiovascular disease—by utilizing bioresorbable, injectable peptide amphiphiles nanocarriers that release therapeutics in response to biochemical cues overexpressed in atherosclerotic lesions. She received her B.S. in chemical engineering from the University of Oklahoma and her M.S. and Ph.D. in biomedical engineering from Duke University.  For her thesis, she developed a clinically translatable, tissue-engineered model of vasculogenesis by incorporating endothelial progenitor cells within biofunctionalized poly(ethylene glycol) (PEG) hydrogels.

She was previously a postdoc at the University of Colorado’s Soft Matter Research Center where she investigated the cytocompatibility of PEGylated ‘clickable’ synthetic nucleic acids for gene delivery. Her career goal is to become an independent investigator developing advanced therapeutic biofunctional materials to resolve cardiovascular disease.

Q: What do you see as the most exciting area of biomaterials research?
A: I am very excited about the recent advancements in biomaterials for nanomedicine.  In particular, the progress in developing nanomaterials that can interact with cells in more sophisticated ways.  We are learning how to regulate the intracellular microenvironment by delivering biomaterials that contain gene-editing tools like CRISPR-Cas9, as well as developing materials that can manipulate the spatial presentation and activation of endogenous proteins through force-loading.  In addition, utilizing logic gate systems to couple extracellular and intracellular-responsive nanomaterials are enabling therapeutic “circuits” that more precisely deliver drugs and regulate cellular responses, ultimately allowing us to engineer biomaterials that can truly sense, guide, and regulate tissue growth and repair.

Greeshma Thrivikraman

Dr. Greeshma Thrivikraman is currently a Postdoctoral Research Associate at the Oregon Health and Science University, Portland, Oregon. Her broad research interests encompass biomaterials, stem cell-based tissue engineering, artificial extracellular matrices and biophysical cues for stem cell differentiation. Greeshma obtained her undergraduate degree in bioengineering from SASTRA University, India and a postgraduate degree in Nanomedical Science from Amrita Centre for Nanosciences, Kerala, India. Subsequently, she pursued her Ph.D. in the interdisciplinary Nano Science and Engineering program from the Indian Institute of Science, Bangalore, India. Her doctorate research was focused on discerning the singular and combinatorial effect of external biophysical stimulation and substrate properties in directing stem cell lineage commitment. In particular, her research results demonstrated how electroconductive matrices in combination with nanoparticles or extracellular matrix proteins can be coupled with direct current and pulsatile electric field stimulation for eliciting neurogenic, cardiomyogenic and osteogenic differentiation of human mesenchymal stem cells.

During her Ph.D. tenure, Greeshma received the Boehringer Ingelheim Fond Travel Grant to undertake a collaborative research project at the Max Bergmann Center for Biomaterials, TU Dresden, Germany. For her postdoc, she was awarded the Canadian Institute of Health Research Postdoctoral Fellowship, which she declined for her current position. Greeshma’s postdoctoral work is centered on engineering 3D cellular microenvironments to fabricate synthetic vascularized bone model to study bone function, disease progression and pharmacological response. Greeshma has authored 2 book chapters and over 18 peer-reviewed research publications in high impact journals including Biomaterials, ACS Applied Materials & Interfaces and Advanced Healthcare Materials. She has also won young researcher awards at several International conferences.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: I have had several rewarding experiences during my graduate studentship as well as my early postdoc career. The most rewarding moment was when I received my doctoral degree from the Indian Institute of Science, Bangalore, India’s premier research institute. Apart from that, the publication of my research results in high impact peer-reviewed journals such as Biomaterials, Advanced Healthcare Materials, and ACS Applied Materials & Interfaces, a short-term internship at the MaxBergmann Center for Biomaterials at TU Dresden, Germany, supported by the Boehringer Ingelheim Fonds and my selection into the ACS Biomaterial Science & Engineering early career advisory board have been momentous career rewarding experiences.

Jingjie Yeo

Dr. Jingjie Yeo’s long-term research goal is to develop a multi-physics molecular simulation platform to model and predict the mechanical, optical, and electrical structure-function relationships of films and hydrogels manufactured from synthetic proteins, and determine the response of human cells in these biomaterials. He is an innovative materials research scientist adept in multi-scale computational modeling of biological materials and processes for successful characterization and prediction of the structure-function relationships of natural and synthetic proteins, graphene, polymers, and complex fluid mixtures. Significantly, he formulated advanced molecular dynamics (MD) simulations to expound the molecular details of β-sheet formation that confers excellent mechanical properties to experimental pristine silk fibroin hydrogels. Yeo also established a coarse-grain MD framework to effectively and efficiently capture the experimental inverse temperature transition of silk-elastin-like protein hydrogels and the concomitant changes in their molecular structures. He is an effective and confident scientific communicator, participating extensively in writing and presenting numerous awarded research projects in academia, computational resources, and industry, including BASF and Proctor & Gamble. He was awarded fully-funded graduate and postgraduate fellowships from Singapore’s A*STAR. As of 2018, he has more than 20 peer-reviewed publications in high impact journals together with 20 collaborators in 4 countries, 21 conference presentations, 3 book chapters, and an h-index of 9. Yeo is currently a Research Scientist in the Institute of High Performance Computing and a Research Affiliate at the Massachusetts Institute of Technology.  He was also a postdoctoral scholar at both MIT and at Tufts University. He received his B.Eng. in 2010 from Singapore’s Nanyang Technological University, majoring in aerospace engineering with a minor in business. He also received his Ph.D. in 2014 from NTU.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: My most rewarding moments are publishing or presenting research results that bore fruit from collaborative, multidisciplinary efforts. These efforts always encompass new perspectives, new friendships, and lasting scientific impact.

Jorge Almodovar

Dr. Jorge Almodovar joined the Department of Chemical Engineering at the University of Arkansas as the Ray C. Adam Chair in August 2018 as an Assistant Professor. He earned his B.S. in chemical engineering from Iowa State University in 2007 and his Ph.D. in chemical engineering from Colorado State University in 2011. At CSU he investigated the delivery and stability of growth factors using polysaccharide-based biomaterials. After CSU, he worked as a Postdoctoral Fellow at the Grenoble Institute of Technology in Grenoble, France, investigating the formation of gradients on polyelectrolyte multilayer films, funded by the Whitaker International Program. Prior to joining U of A, he was a faculty member at the Chemical Engineering Department at the University of Puerto Rico, Mayaguez, were he began an active research group. His research interests include extracellular matrix mimetic biomaterials, cell-material interactions, and biomaterials as therapeutics. His research focus is on the engineering of biomimetic materials—inspired by the native cell environment—for fundamental studies, cell manufacturing, tissue engineering, therapeutics, and regenerative medicine. He is an author of 17 peer-reviewed research articles and 5 book chapters, and an editor for one textbook. He has served as a peer-reviewer for federal grant proposals and for multiple journals in the biomaterials field including ACS Biomaterials Science & Engineering.

Q: Who has been the most important mentor in your career?
A: I have had a number of significant mentors throughout my academic career that it is impossible to pinpoint one. My Ph.D. advisor (Dr. Matt Kipper), my postdoctoral advisor (Dr. Catherine Picart), colleagues from the University of Puerto Rico Mayaguez (Dr. Madeline Torres-Lugo and Dr. Aldo Acevedo), colleagues from other institutions (Dr. Andres Garcia), and current colleagues at the University of Arkansas have all positively impacted my career.

Jun Deng

Dr. Jun Deng is an Associate Professor and Doctoral Supervisor at Third Military Medical University (Army Medical University) in Chongqing, China. He received his B.S. degree in chemistry and chemical engineering from Sun Yat-sen University in Guangzhou, China, and in 2010 he received his Ph.D. in polymer science and engineering from Zhejiang University in Zhejiang, China, in 2016. He currently works at Institute of Burn Research, Southwest Hospital, State Key Lab of Trauma, Burn and Combined Injury, Army Medical University.

His primary research interest is in functional material surface construction and its application in early diagnosis and treatment of diseases. He has published 20 peer-reviewed papers as the first author or corresponding author, with a total impact factor of over 100. He has achieved a patent conversion of over 2 million RMB, 1 book and given some keynote and plenary lectures globally. He runs a prolific research program with funding from the National Natural Science Foundation of China (NSFC), Army of China, and Army Medical University for Tissue Engineering and Regenerative Medicine.

Q: What do you see as the most exciting area of biomaterials research?
A: In my view, the most exciting area of biomaterials research should be the nanobiotechnology, which refers to the intersection of nanotechnology and biology.

Kelsey M. Kennedy

Dr. Kelsey Kennedy is a biomedical engineer with a skillset placed at the intersection of optical imaging of biomaterials and tissues, biomechanics, and translation of medical technologies. She has demonstrated success in implementing imaging techniques that bridge the gap between in vitro or ex vivo imaging in pre-clinical settings, and in situ imaging in clinical settings. She has published over 20 peer-reviewed journal articles and magazine articles on the evaluation of tissue microstructure and mechanical behavior using 3D optical imaging.

Now at the Laboratory for Stem Cells and Tissue Engineering at Columbia, University, she is applying imaging- and biomechanics-based approaches to tissue engineering to help drive technical innovation in osteochondral disease modeling and to enable translation of microphysiological systems for the study of cancer metastasis. Prior to joining Columbia in 2017, Dr. Kennedy completed her Bachelors in Mechanical Engineering at the University of Notre Dame and her Ph.D. at the University of Western Australia. During her Ph.D., she co-founded OncoRes Medical, a medical imaging startup that is commercializing a device for detecting the tumor boundaries during breast cancer surgery.

Mohammad Mahdi Hasani-Sadrabadi

Dr. Mohammad Mahdi Hasani-Sadrabadi received his B.S. degrees in polymer engineering in 2007 and biomedical engineering in 2009 and an M.S. degree in polymer engineering in 2009 all from Tehran Polytechnic, then he got his M.Eng. in bioengineering and biotechnology in 2012 at Swiss Federal Institute of Technology in Lausanne, Switzerland. In 2013, he got his first Ph.D. in polymer engineering from Tehran Polytechnic, where he spent a year as a lecturer at the Biomedical Engineering Department. Then he left Tehran and started his second Ph.D. in 2014 in  a bioengineering program at the G. W. Woodruff School of Mechanical Engineering at Georgia Institute of Technology. He successfully published over 20 journal papers during his three-year Ph.D. at Georgia Tech, working on developing microfluidics platform to improve the fabrication and analysis of cancer nanomedicine.

Over this period, he also collaborated with UCLA School of Chemistry and UCLA Dental School to develop new biomimetic materials and biomaterials for craniofacial tissue regeneration. He started his research experience back in 2005 by working on tuning the physicochemical characteristics of polyelectrolytes based on the biopolymers. He then tried to develop functional materials as biomimetic ion-conductor membranes for power generation, drug delivery applications and lately for tissue engineering and immunoengineering applications.

Recently, he has started his appointment as an Assistant Project Scientist in the Bioengineering Department at UCLA for developing novel biomaterial-based approaches to improve immunotherapy.

Mariana B. Oliveira

Dr. Mariana B. Oliveira is a Postdoctoral Researcher at CICECO – Institute of Materials, at the University of Aveiro (Portugal) since 2016. Oliveira completed her M.S. in biomedical engineering at the University of Minho (Portugal) in 2010 and completed her Ph.D. in 2014 in biomedical engineering at the University of Minho. During her Ph.D., she developed patterned platforms based on wettability contrast for the high-throughput characterization of biomaterials’ physicochemical properties and biomaterial-cell interactions. She spent a period of her Ph.D. at Technion – Israel Institute of Technology, where she worked with cell encapsulation strategies. Previous international experience, acquired at the University of Valladolid (Spain) during her M.S., focused on the production of elastin-like recombinant peptides and their application as biomaterials

Her main research interests include the development of biomaterial-based regenerative strategies, with main emphasis on bone regeneration. Oliveira has also been dedicated to the design of miniaturized systems to assess cell-biomaterials interactions, assembly of tailor-made bioreactors for cell response modulation, and development of new biomaterials processing techniques. Currently, she is also focused on the development of biomaterials for the encapsulation of pancreatic cells tackling the treatment of diabetes.

Oliveira is the principal investigator of a research project awarded by the Portuguese agency for science and technology (FCT). For the last two years, she has been the main supervisor and integrated the supervision teams of students of different academic degrees. Mariana authors and co-authors more than 30 scientific publications.

Q: What do you see as the most exciting area of biomaterials research?
A: The most exciting aspect of biomaterials research for me is the ability to merge well-established and recently discovered concepts of tissues and organ systems’ physiology with technology to achieve effective designs for regeneration and disease therapies. I am interested in the deconstruction and isolation of striking factors that drive the efficacy of biomaterial-based cell-modulating systems.

Md “NABI” Nurunnabi

Dr.  Md “Nabi” Nurunnabi is a Postdoctoral Research Fellow at Harvard Medical School, Massachusetts General Hospital. He was born in Bogura, Bangladesh in 1984. He received his B.S. with honors in pharmacy from the University of Development Alternative in 2007, in Bangladesh. Nurunnabi received his M.Eng. in chemical and biological engineering and Ph.D. in polymer science and engineering with bioengineering major in 2010 and 2014, respectively from Korea National University of Transportation, South Korea. His masters and doctoral research focused on fabricating and polymeric modification of nano-biomaterials and understanding their feasibility as drug delivery and imaging agents. During his Ph.D., Nurunnabi conducted part of his project at University of Utah, where he successfully completed a project on oral delivery of GLP1 under supervision of Dr. You Han Bae, that resulted a U.S. patent and publications. He has developed graphene based optical contrast agents for cancer imaging, boron nitride-based sensing platform for quantitative analysis of dopamine from blood, bile acid transporter specific oral therapeutic and diagnostic delivery, biomarker specific on targeting drug delivery for cancer, inflammation and fibrosis imaging and therapy. Beside academic research, he has experienced of industrial research and starting start-up where he translated product to third party through sub-licensing. His current research focused on designing and developing of advanced bioengineered materials for cell specific delivery of therapeutic and diagnostic delivery for better management of patient clinically. He has published 40+ peer reviewed articles, has 10 patents issued and pending, 2 of which has been licensed or sub-licensed to companies. Nurunnabi’s career goal is to implement his experience and expertise to the healthcare sector for better management of disease through developing new tools and techniques.

Q: Who has been the most important mentor in your career?
A: My pre-doctoral mentors; Professor Yong-kyu Lee (Korea National University of Transportation) and Professor You Han Bae (University of Utah), have been the most important mentors for my career.

Neelkanth M. Bardhan

Dr. Neelkanth “Neel” M. Bardhan holds a B.Tech. from the Indian Institute of Technology, Bombay, in Mumbai, India, and was awarded the 2010 Institute Silver Medal. He then did his Ph.D. in materials science and engineering from the Massachusetts Institute of Technology in Cambridge, Massachusetts. For his Ph.D. research on the use of biologically-templated, carbon-based nanomaterials for biosensing and diagnostic applications in cancer imaging and detection of deep-tissue pathogenic infections, Bardhan was a recipient of the MRS Graduate Student Gold Award, awarded by the Materials Research Society in April 2015. Following his Ph.D., Bardhan was funded by the 2016 Misrock Postdoctoral Fellowship, and the 2016-17 RLE Translational Fellows Program, working with oncologists at the Massachusetts General Hospital, towards clinical translation of his nanotechnology-based approach to cancer imaging. Bardhan is currently the 2017-19 Mazumdar-Shaw International Oncology Postdoctoral fellow, affiliated with The Koch Institute for Integrative Cancer Research at MIT, working at the interface of materials science and cancer biology for developing an alternative therapeutic approach for ovarian cancer using near-infrared phototherapy, for patients who have become resistant to standard chemotherapy agents. Bardhan has served as a Peer Reviewer for Nano Letters, ACS Nano, and ACS Biomaterials Science & Engineering, among other journals. Bardhan is listed as an Inventor on 2 issued U.S. patents and has 4 additional patent filings in progress; and has authored several first-author publications. In addition to research, Bardhan enjoys being actively involved in youth leadership, with contributions in issues pertaining to science funding, climate change and sustainability, and science outreach.

Q: Who has been the most important mentor in your career?
I believe that my Ph.D. dissertation advisor, Professor Angela Belcher, has been the most important mentor in nnb career. Professor Belcher has taught me the importance of being able to dream big, and challenge the conventional wisdom even in the face of doubting critics, backed up by solid research and facts-based evidence.

Neus Feliu

Dr. Neus Feliu got a B.S. in chemistry from Universitat de Barcelona in 2007 and obtained her M.S. degree in biomedical materials from the Royal Institute of Technology in Stockholm in 2009. She obtained her Ph.D. degree in medical science from the Karolinska Institutet in Stockholm, in the field of engineered nanomaterials for biomedical applications in 2014. Afterwards, she joined a research group at the Department of Clinical Science and Technology at KI as a postdoctoral researcher. She continued her career as Vinmer and Marie Curie Fellow at the Department of Laboratory Medicine, Clinical research Center, KI, Stockholm, Sweden.

She is currently a Research Associate at the Center for Hybrid Nanostructures, Hamburg University. Her research focuses on the synthesis and characterization of micro- and nanoparticles, with the aim to develop smart multifunctional materials for a wide range of bio-applications including sensing and delivery. In particular, her interest focuses on better understanding the interactions and correlations of materials with biological systems involving biocompatibility studies with living cells and explore their use in the medical field.

Q: Who has been the most important mentor in your career
A: During my career I have been very fortunate to have the opportunity to meet wonderful, knowledgeable, and encouraging mentors, who helped me to build my career in both personal and professional aspects. My special thanks goes to my Ph.D. co-supervisior Professor Andreas Nyström, an enormous source of inspiration, extremely knowledgeable, and one of the most honest persons I have met. He has helped me to stand out in challenging situations, and had a long-lasting, positive, and stimulating impact on me.

Nuria Oliva-Jorge

Dr. Nuria Oliva-Jorge graduated from Institut Quimic de Sarria, Universitat Ramon Llull, in Barcelona, Spain, with a B.S. in organic chemistry. She received her Ph.D. in medical engineering and medical physics at the Harvard-MIT Division of Health Sciences and Technology, focused on the development of a novel adhesive hydrogel and its use as a model platform to understand how disease microenvironment affects material performance and how to leverage those cues to attain tumor cell-selective delivery of chemotherapy in a local and sustained manner.

She then spent a year at Brigham and Women’s Hospital at Harvard Medical School as a NIH Ruth L. Kirschstein Postdoctoral Fellow. She is currently a TECNIOspring PLUS Postdoctoral Fellow, within the Marie Skłodowska-Curie Action (Horizon 2020) and ACCIO funding (Generalitat de Catalunya), working in a collaborative project between Imperial College London and Institut Quimic de Sarria. Nuria’s work focuses on the development of smart nanomaterials for controlled delivery of growth factors for wound healing and bone regeneration.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: A few weeks ago, after giving a talk at the New Scientist Live festival, a young girl approached me and told me that she loved my research and she wanted advice on what degree to study to do the research I do. Knowing that I have inspired a young woman to pursue a career in STEM is definitely the most rewarding moment in my career as a scientist, and I work every day to continue to inspire more girls to follow their dreams and realize they can be anything they set their minds to. 

Rachel Letteri

Dr.  Rachel Letteri is an Assistant Professor of Chemical Engineering at the University of Virginia (UVA).  She obtained a B.S. in chemical and biomolecular engineering from the University of Notre Dame in 2010 and a Ph.D. in polymer science and engineering from the University of Massachusetts, Amherst, in 2016.  Her graduate research, under the direction of Professor Todd Emrick and Professor Ryan Hayward, involved the synthesis and assembly of functional hydrophilic polymers.  Specifically, she synthesized polymer-peptide conjugates and polymer zwitterions in linear and comb architectures, and evaluated these materials as responsive emulsion surfactants and non-viral gene therapy reagents.  In 2014, she was awarded an NSF East Asia Pacific Summer Institutes Fellowship to conduct research on zwitterionic polymer nanocomposites at Nanyang Technological University in Singapore.  Letteri joined the laboratory of Professor Karen Wooley in the Department of Chemistry at Texas A&M University as a Postdoctoral Researcher in 2016, and investigated the impact of stereochemistry on the assembly of amphiphilic block polypeptides.  While at Texas A&M, she led the organization of an ongoing Science Night program, which brings together ca. 15 science and engineering groups to provide an evening of hands-on activities for students and their families at local elementary schools.  At UVA, the Letteri group will engineer adaptive polymer-peptide composites that display a breadth of thermomechanical properties and promote productive interactions with biological systems.  By leveraging the rich variety of polymer and peptide molecular interactions in solution and at interfaces, her lab will develop materials with shear-thinning, self-healing, shape-memory, and molecular recognition properties to enable 3D printing of regenerative scaffolds and new therapeutic strategies for Amyotrophic Lateral Sclerosis, among other applications.

Q: What do you see as the most exciting area of biomaterials research?
A: Interfacing modular, highly tunable materials with complex, highly functional biological systems to enable regenerative medicine is an incredibly exciting area of biomaterials research that integrates a broad range of biomaterials and a rich diversity of techniques, approaches and researchers to improve the lives of patients.  It is tremendously inspiring and fulfilling to have the opportunity to work with, mentor, and learn from researchers across medicine, biology, chemistry, physics, material science, and engineering to continuously advance the state-of-the art materials, therapies, measurement and characterization tools, and computational methods needed to address this grand challenge.

Rong Yang

Dr. Rong Yang a classically trained chemical engineer conducting research on infectious disease treatments. She completed his Ph.D. at MIT in 2014, followed by postdoctoral training at Boston Children’s Hospital and Harvard Medical School. She is currently a research assistant professor at Harvard Medical School, and will soon take on a tenure-track position in the Smith School of Chemical and Biomolecular Engineering at Cornell.

Her research focuses on the design of functional materials that interface with bacteria and influence their behavior, including generating vapor-based technologies for surface modifications with molecular-level precision. Applications of the modified surfaces range from lowering the cost of seawater desalination to reducing implant-related infections. The vapor techniques are scalable; the functional surfaces are thus transferrable to industrial production.

She is also interested in understanding surface interactions from a fundamental perspective. The vapor-deposited functional materials can be easily integrated into the state-of-the-art technological platforms. This allows for quantifying bacteria-surface interactions on the piconewton level, to develop methodologies to capture the spatial-temporal evolution of biofilm formation, and measure its density and viscoelastic properties in situ. Later research at Harvard Medical School focused on developing infectious disease treatments using his material design expertise. She works with otitis media, the most common reason for antibiotic prescriptions to U.S. children, and developed a local treatment that eliminates systemic antibiotic exposure. The treatment is under preparation for human clinical trials.

Her research program focuses on vapor-deposited biointerfaces for healthcare and sustainability. Her efforts have been directed towards understanding bacteria-surface interactions on a molecular level and applying the insight to developing therapeutic platforms for infectious diseases, such as surface-engineered nanoparticle- and membrane-based therapies.

Q: What do you see as the most exciting area of biomaterials research?
A: I am most excited about controlling biofilm phenotype via surface modifications. The insight into how bacteria respond to surface properties could allow us to harness the biosynthesis capability of biofilms while suppressing fouling and pathogenicity. The insight could also shed light on the evolution and principles of multicellularity.

Shane Browne

Dr. Shane Browne received a B.Eng. in biomedical engineering and a Ph.D. from the National University of Ireland Galway. His doctoral thesis was supervised by Professor Abhay Pandit at the Centre for Research in Medical Devices at NUIG, and focused on the control of inflammation and angiogenesis via therapeutic release from a multi-modal collagen hydrogel system. During his doctoral studies, he was awarded travel grants from the European Molecular Biology Organisation and the Deutscher Akademischer Austauschdienst to work with Professor Katja Schenke-Layland at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, in Stuttgart, Germany.

He is currently a Postdoctoral Research Fellow at the Department of bioengineering at the University of California Berkeley under Professor Kevin Healy. His research interests include the development and testing of biomaterials for the delivery of therapeutics and semi-synthetic extracellular matrices  for the delivery of stem cell-derived cells for therapeutic vascularisation. His postdoctoral work has been funded by prestigious fellowships from the Irish Research Council and the American Heart Association.

He has authored manuscripts in leading journals in the field and has presented his research at both national and international conferences. In addition, he has been awarded the European Doctoral Award by the European Society for Biomaterials.

Shengjie Ling

Dr. Shengjie Ling is assistant professor in the School of Physical Science and Technology at ShanghaiTech University. His research focuses on developing biopolymer functional materials through the integration of synchrotron-based characterization, computational modeling and bioinspired & biomimetic fabrication.

He obtained his B.S. degree from the Zhejiang University of Technology (2009) and Ph.D. from Fudan University (2014).

During 2012-2013, He awarded the State Scholarship Fund of China to pursue his study at ETH Zurich, Switzerland, as a joint Ph.D. student.

Prior to joining ShanghaiTech University, he worked as a postdoctoral associate at MIT and Tufts University (2014-2017).

Q: What do you see as the most exciting area of biomaterials research?
A: The most exciting area of biomaterials research for me is to integrate computational modeling, experimental characterization and synthesis to produce biomaterials with optimized  “structure-property-function” relationships. The combination of computational modeling and experimental techniques provides synergistic support to design a material from the atomic- to macro-scale, and all biomaterials are included in such region.

Tushar Kumeria

Dr. Tushar Kumeria is an Australian National Health and Medical Research Council Early Career Fellow at the School of Pharmacy, The University of Queensland (UQ), Australia. He has co-authored 47 high-impact journal publications in various internationally renowned journals in the field of nanomaterials, biomaterials, sensing, and drug delivery. He completed his Ph.D. in 2015 from the University of Adelaide with a Doctoral Thesis Medal and Dean’s Commendation Letter. In 2015, he moved to the U.S. and spent two years at University of California, San Diego, as a postdoc with Professor M. J. Sailor’s group.

His research expertise lies in nanoporous materials and their composite for applications in photonics, sensing, and drug delivery. His current research focus is on:

  1. Porous silicon based delivery systems for highly efficient and targeted delivery of protein/biologics via oral or other administration route.
  2. Porous silicon/Polymer composite and porous titanium dioxide based scaffolds/implants that enable local release of therapeutics and growth factors for accelerated bone regeneration,
  3. Porous silicon or porous alumina photonic crystals based point-of-care sensors for diagnostics and environmental applications.

Q: Who has been the most important mentor in your career?
A: My most important mentors is my postdoc advisor Professor M. J. Sailor at University of California-San Diego. I have not only learnt about science, but also management of a great group/team.

Wei Zhang

Dr. Wei Zhang received her Ph.D. in stem cells and regenerative medicine from Zhejiang University, China in 2015. During 2015-2018, she did postdoc work at Umeå University in Sweden. In September 2018, she returned to China to set up her own research group as an Associate Professor in the  School of Medicine at Southeast University.

Her research mainly focuses on tissue engineering and regenerative medicine, which involve interdisciplinary studies of biomedicine, materials science and clinical medicine. Her research utilizes stem cells, biomaterials (silk and collagen) and signals (physical stimuli and bioactive factors) to promote the repair and regeneration of cartilage, bone, skin, cornea and abdominal tissue etc. She works both on basic research and translational research from scaffold fabrication, in vitro evaluation, biocompatibility evaluation, small animal study, large animal study, controlled clinical trial to medical device registration. These findings will promote the development of effective regenerative medicine therapies to treat common tissue injuries, and facilitate the translation of innovative researches from bench to bedside.

Q: What has been the most rewarding moment in your career as a scientist or engineer?
A: Three years ago I was involved in a translational research of a novel biomaterials-based scaffold. This scaffold was used on 36 patients with large skin wounds and effectively promoted the wound healing speed and reduced the occurrence of adverse events. At that time I recognized that what I researched could really help the patients and improve their quality of life.

Yi-Cheun Yeh

Dr.  Yi-Cheun Yeh is an Assistant Professor at the Institute of Polymer Science and Engineering in National Taiwan University. She received her B.S. and M.S. in Chemistry from National Taiwan Normal University. Yi-Cheun pursued her Ph.D. in Chemistry at University of Massachusetts, Amherst under the guidance of Professor Vincent Rotello.  Her doctoral work mainly focused on engineering the Nano-Bio interface through the tailoring of the surface monolayers of nanomaterials.  Upon graduation, Yi-Cheun moved to Philadelphia to perform her postdoctoral studies in the polymeric biomaterials laboratory of Professor Jason Burdick, with the focus of developing functional polymers for biomedical applications.  The goal of her research is to engineer functional materials to obtain fundamental understanding and practical applications in nanomedicine, tissue engineering and biofabrication.

Towards this goal, her lab will develop programmable nanocomposite hydrogels through the integration of polymer synthesis and surface functionalization of nanoparticles. The interface of nanoparticles and polymers will be tailored and manipulated with multiple chemical approaches to present dynamic and user-defined features. The utilization of diverse chemistry on both nanomaterials and biomaterials provides a potent strategy in creating versatile hybrid materials to engage in the cutting edge Material-Biology research, and to serve as a promising platform for next-generation smart materials for biomedical applications.

Q: What do you see as the most exciting area of biomaterials research?
A: I think the most exciting area of biomaterials research would be the use of biofabrication techniques to construct biomimetic environment for tissue engineering.

Yun Xiao

Dr. Yun Xiao received a B.Eng. in biomedical engineering from Sichuan University in 2010 and a Ph.D. in chemical engineering from the University of Toronto in 2016. She returned to Sichuan University to join the faculty and currently is an Associate Professor at the National Engineering Research Center for Biomaterials. Her research is at the interface of materials science and cell biology, with particular focus on microenvironment regulation of stem cell behavior to promote tissue regeneration by biochemical and biophysical stimuli. She has extensive experience in cardiac tissue engineering and wound healing particularly with collagen-based biomaterials.

Xiao participated in developing the Biowire system, a novel ‘heart-on-a-chip’ platform for predictive cardiac drug testing, which is being commercialized by TARA Biosystems. In collaboration with cardiac surgeons, she demonstrated for the first time that one can rejuvenate mesenchymal stem cells from aged human patients using biomaterials and this work was published and highlighted in the Journal of the American College of Cardiology.

In her work published in the Proceedings of the National Academy of Sciences, Xiao demonstrated that the hydrogel with covalently immobilized QHREDGS promoted wound healing by enhancing cell survival and epithelial cell migration both in vivo and in vitro.

Xiao is currently working on developing biomaterials that present biophysical cues with improved spatiotemporal control and modulating cell-microenvironment interactions under dynamic mechanical loadings such as in musculoskeletal system.

ACS on Campus: Empowering Early Career Researchers at NIT Calicut

ACS Publications set off to NIT Calicut in India on September 7, 2018,  to meet with local early career researchers and students. The event’s distinguished speaker list featured Professor Abhishek Dey, Associate Editor for ACS Catalysis and an Associate Professor at the Indian Association for the Cultivation of Science, as well as  Professor Thalappil Pradeep, an Associate Editor for ACS Sustainable Chemistry and Engineering and the Chair Professor at Deepak Parekh Institute and Professor of Chemistry at the Indian Institute of Technology Madras, Chennai, India.

Professor Dey shared best practices on scholarly publishing and delivered his lecture on “Communicating Science in Popular Writing Format,” while Professor Pradeep talked at length about the ins and outs of peer review. Professor Pradeep’s scientific lecture on “Reactions Between Nanoparticles” captivated the audience.

The program saw participation from more than 120 early career researchers and faculty members from the institution. Attendees were able to interact with the event’s featured speakers, as well as ACS staff in attendance. They were able to share insights and discuss the positive impact that ACS Publications is making to the research output of NIT Calicut. When researchers publish with ACS, their work earns more citations, showing off the research done at NIT Calicut to the world.

ACS on Campus is honored to collaborate with NIT Calicut and are grateful for the support provided by Professor Jaydeep and the team from NIT Calicut to make this day a great success.

ACS Editors’ Choice: Dehydration without Heating — and More!

This week: Dehydration without heating, optical tweezers microrheology, spectroscopy of reactive complexes and solvated clusters — and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!
Peptide-Based 68Ga-PET Radiotracer for Imaging PD-L1 Expression in Cancer

Mol. Pharmaceutics, Article ASAP
DOI: 10.1021/acs.molpharmaceut.8b00399
Liquid Phase Acoustic Wave Exfoliation of Layered MoS2: Critical Impact of Electric Field in Efficiency

Chem. Mater., Article ASAP
DOI: 10.1021/acs.chemmater.8b01506
In Situ Passivation of PbBr64– Octahedra toward Blue Luminescent CsPbBr3 Nanoplatelets with Near 100% Absolute Quantum Yield

ACS Energy Lett., 2018, 3, pp 2030–2037
DOI: 10.1021/acsenergylett.8b01025
Dehydration without Heating: Use of Polymer-Assisted Grinding for Understanding the Stability of Hydrates in the Presence of Polymeric Excipients

Cryst. Growth Des., Article ASAP
DOI: 10.1021/acs.cgd.8b00687
Examining the Association between Body Burdens of Harmful Chemicals and Heaviness of Marijuana Smoking

Chem. Res. Toxicol., Article ASAP
DOI: 10.1021/acs.chemrestox.8b00160
Optical Tweezers Microrheology: From the Basics to Advanced Techniques and Applications

ACS Macro Lett., 2018, 7, pp 968–975
DOI: 10.1021/acsmacrolett.8b00498
Spectroscopy of Reactive Complexes and Solvated Clusters: A Bottom-Up Approach Using Cryogenic Ion Traps

J. Phys. Chem. A, Article ASAP
DOI: 10.1021/acs.jpca.8b05712
Love ACS Editors’ Choice? Get a weekly e-mail of the latest ACS Editor’s Choice articles and never miss a breakthrough!

Meet the Winners of the 2018 ACS Infectious Diseases Young Investigator Award

The ACS Infectious Diseases Young Investigator Award recognizes outstanding young investigators in the field of infectious diseases. The award is given by ACS Infectious Diseases and the ACS Division of Biological Chemistry. The 2018 ACS Infectious Diseases Young Investigator Award goes to Anushree Chatterjee, Principal Investigator, University of Colorado; Ting Lu, Associate Professor, University of Illinois; and Emily Derbyshire, Assistant Professor, Duke University.

As winners of the 2018 ACS Infectious Diseases Young Investigator Awards, Chatterjee, Lu, and Derbyshire will each receive a plaque, an award of $1,000, and up to $500 in travel reimbursement to attend the 256th ACS National Meeting & Exposition in Boston, and present at an ACS Division of Biological Chemistry symposium in their honor. The journal and the Division encourage you to attend the ACS Infectious Diseases Young Investigator Awards Symposium August 21, 2018, from 1:30-4:00 P.M. during the National Meeting in Room 153 B at the Boston Convention & Exhibition Center.

I got the chance to chat with award winners Anushree Chatterjee and Ting Lu, read on to find out more about them:

Anushree Chatterjee:

How did you get into your field of study?

I completed my Ph.D. in chemical engineering at the University of Minnesota, working with Prof. Wei-Shou Hu and Prof. Gary Dunny on understanding molecular mechanisms of antibiotic resistance transfer in the clinical superbug Enterococcus faecalis using mathematical modeling and experimentation.  Before joining the Department of Chemical and Biological Engineering at the University of Colorado Boulder, I was a postdoctoral research fellow with Dr. Alan S. Perelson at the Theoretical Biology and Biophysics group at Los Alamos National Laboratory where I performed both mathematical modeling and experiments to study gene regulation and evolution of drug-resistance in Hepatitis C virus. I was and continue to be fascinated by living systems, and how dynamic they are. With more systems biology-based understanding we are now learning that infectious diseases are very dynamic and heterogeneous, whereas our therapies are slow and more static in nature. It was during my Ph.D. research working on bacteria and postdoc research working on viruses that I deeply understood the global impact of antimicrobial resistance and how underprepared we are as a human race to face this challenge. Therefore I decided to commit my career towards solving the problem of antimicrobial resistance.

What’s the most exciting discovery you’ve made in your career so far?

There have been a few; I would say three to be exact.  Our lab is building a new therapeutic platform called Facile Accelerated Specific Therapeutic (FAST) for the development of novel antibiotics against multi-drug resistant (MDR) bacterial clinical isolates as well as evolving pathogens in a time scale of days. The FAST platform uses interdisciplinary approaches including synthetic biology, systems biology, synthetic chemistry, and host-pathogen infection biology to engineer exogenously delivered artificial nucleic acid-based antisense therapeutics that can target any desired gene in a pathogen-specific manner for targeted inhibition without the need for any molecular cloning. This therapeutic is very potent and kills a wide range of clinical isolates of MDR bacteria. I am also excited about another highly promising new approach invented in our lab involving the development of a unique semiconductor material-based quantum dot-antibiotic (QD ABx). The QD ABx uses stimuli such as visible light-activation to produce reactive oxygen species to kill MDR clinical bacterial isolates including methicillin-resistant Staphylococcus aureus, Klebsiella pneumoniae, and Salmonella typhimurium, and carbapenem-resistant Escherichia coli. Finally, using principles of evolutionary biology, systems biology, and synthetic biology our lab has developed an approach called “Controlled Hindrance of Adaptation of OrganismS” or “CHAOS” that can slow the evolution of antibiotic resistance by interfering with processes involved in adaptive resistance. I think all three platforms offer promise, and we now need to translate these.

What are you looking forward to most about your research?

I am looking forward towards building therapeutic platforms that can significantly accelerate drug development so that we can overcome outbreaks of infectious diseases, hopefully in “real-time” in the future. We need to understand how organisms adapt to therapies and also develop therapeutic platforms that can accelerate drug development, intelligently target these microbes to eliminate them as well as reduce the emergence of resistance, and in case there is the emergence of resistance the designed therapies should be adaptable enough to keep up with evolution. In this effort, the next steps in our lab include translating FAST and QD Abx platforms by performing pre-clinical research and working with experts to make these therapies reach the clinic. We are focusing on how can we make our therapies more effective in terms of activity, transport, and bioavailability. Our lab understands that we need to do this urgently because the antimicrobial resistance crisis is “happening now” and will only get worse. We as a human race need to catch up quickly to these smart evolving pathogens.

Ting Lu

How did you get into your field of study?

I am a physicist by training but always fascinated by biology. In my graduate study at UCSD, I was very fortunate to join the laboratories of Professor Jeff Hasty and Professor Peter Wolynes, who together brought me to bacterial, synthetic biology—the modeling, design, and construction of bacterial gene networks for functional programming. Under the guidance of Professor James Collins (Wyss Institute) and Professor Ron Weiss (MIT) as a postdoc, I advanced my research interest and further identified the focus on therapeutic applications of synthetic biology. This led me to the study on the treatment and prevention of infectious diseases.

What is the most exciting discovery you have made in your career so far?

One major focus of my research is to advance the engineering methodologies for lactic acid bacteria (LAB) and to utilize them to create designer strains for controlling infectious diseases. Recently, we developed a versatile pathway-engineering platform for LAB, which offers a systematic strategy to construct and optimize complex LAB biosynthetic pathways. With the platform, we have successfully overproduced nisin, a potent antimicrobial agent, and constructed probiotic biofilm formers that can potentially outcompete pathogens like listeria and staphylococcus species.

What are you looking forward to most about your research?

I hope to advance our current research from in vitro validation to in vivo test in animal models. I am also very keen to push the boundary of designer probiotics in general.

Editor in Chief of ACS Infectious Diseases Courtney Aldrich on Emily Derbyshire:

“Dr. Emily Derbyshire is an Assistant Professor in the Department of Chemistry at Duke University. She received her Ph.D. from Berkeley with Michael Marietta then completed a postdoc with Jon Clardy at Harvard Medical School. Dr. Derbyshire studies the fundamental biology of the liver stage of malaria infection and also develops small molecule antimalarials through innovative target- and phenotypic-based approaches.”



Chemical Research in Toxicology Honors Simon Wan Chan

The 2018 Chemical Research in Toxicology Young Investigator Award goes to Dr. Simon Wan Chan, Associate Profesor in the Department of Chemistry at The Hong Kong University of Science and Technology. He also received the 2017 Research Article of the Year Award Lectureship from the Journal of Agricultural and Food Chemistry and the ACS Division of Agrochemicals. Dr. Chan will receive the award and deliver a lecture titled “Chemical approaches to investigate the toxicity of aristolochic acids” during the Chemical Research in ToxicologyYoung Investigator Award session on Tuesday afternoon at the Fall National Meeting in Boston.

Dr. Chan’s current research interest focuses on developing chromatographic and mass spectrometric methods. These methods can be used to identify and quantify toxic chemicals for food safety testing. They can also be used to study chemically/physically-induced damage to biological macromolecules such as DNA, RNA, etc. that is related to human diseases, and to investigate the biological consequence of external stimuli by using a systematic metabolomics approach.

“Dr. Chan has an extremely strong record of contributions in the area of environmental toxicology, including his work in delineating aristolochic acid exposure pathways, the implementation of protein biomarkers of exposure to formaldehyde and acetaldehyde, as well as the development of new bioanalytical chemistry approaches to address potential DNA damage arising from irradiation,” Professor Shana J. Sturla, Editor-in-Chief of Chemical Research in Toxicology.

Dr. Chan is a worthy recipient of the Chemical Research in Toxicology Young Investigator Award,” says Professor Thomas Spratt, Program Chair of the Division of Chemical Toxicology. “His research has focused on the chemical toxicology of food safety.  His most important paper,  (J. Agric. Food Chem., 64:5928−5934), was named the “Research Article of the Year” in the Journal of Agricultural and Food Chemistry.  Through the work of Arthur Grollman and colleagues, we know that aristolochic acids are the cause of Balkan Endemic Neuropathy.  Simon Chan showed that humans can be exposed to aristolochic acids directly through corn and wheat because these plants can absorb aristolochic acids from the soil. This work will impact strategies that we use to decrease exposure to these harmful environmental toxicants.  However, my favorite manuscript is one he published in Chemical Research in Toxicology (Chem. Res. Toxicol. 29:1865-1871) in which he showed that formaldehyde reacts with cysteine residues to form a cyclic thia-proline residue.  This modification alters the backbone structure of proteins because prolines exist in the cis-conformation.  I will be looking forward to learning whether this modification does impact protein activity and whether cells utilize this modification as a surveillance system for formaldehyde-producing oxidants.   He shows how careful analytical chemistry can be used to solve important medical problems

“As a postdoc with my group, Dr. Chan had wide-ranging and eclectic research interests — he was an engine for new ideas and new methods,” says Peter C. Dedon, the Underwood-Prescott Professor of Biological Engineering at the Massachusetts Institute of Technology. “As a member of the faculty at Hong Kong University of Science and Technology, he has now proven himself to be more than just a talented analytical chemist, with a long and diverse list of scientific accomplishments. More importantly, his work is having a true impact on public health policy. This is why he so deserves the Chemical Research in Toxicology Young Investigator Award.”

Other important Chemical Research in Toxicology articles by Dr.Simon Wan Chan include:

  1. Quantitation of the DNA Adduct of Semicarbazide in Organs of Semicarbazide-Treated Rats by Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry: A Comparative Study with the RNA Adduct
    Chem. Res. Toxicol., 2016, 29 (9), pp 1560–1564
    DOI: 10.1021/acs.chemrestox.6b00232
  2. Identification of Protein Thiazolidination as a Novel Molecular Signature for Oxidative Stress and Formaldehyde Exposure
    Chem. Res. Toxicol., 2016, 29 (11), pp 1865–1871
    DOI: 10.1021/acs.chemrestox.6b00271
  3. Facile Formation of a DNA Adduct of Semicarbazide on Reaction with Apurinic/Apyrimidinic Sites in DNA
    Chem. Res. Toxicol., 2016, 29 (5), pp 834–840
    DOI: 10.1021/acs.chemrestox.6b00011