Medicinal chemistry technology evolves rapidly these days and new developments are continually changing the way we live and work. This is especially true in highly competitive industries such as pharmaceutical research and development and drug discovery.
In these industries, the introduction of new enabling technologies that accelerate progress, reduce cycle time, and cut costs is of high importance, says Stevan W. Djuric, Ph.D. He and his colleague Anil Vasudevan, Ph.D., in the Discovery Chemistry and Technology group at AbbVie are charged with developing technologies that will do just that.
This fall, Djuric and Vasudevan are also teaming up to serve as Guest Editors of an ACS Medicinal Chemistry Letters Special Issue that will explore the latest medicinal chemistry technology:
“Med Chem Tech: Driving Drug Development”
Submission Deadline: Feb. 15, 2018
Advances in Medicinal Chemistry Technology
Earlier this year, ACS Medicinal Chemistry Letters collaborated with Journal of Medicinal Chemistry, ACS Combinatorial Science, and Chemical Reviews to publish the Virtual Issue “Technological Advances in Medicinal Chemistry.” It consists of 26 papers published in the journals between 2013 and 2016, including six ACS Medicinal Chemistry Letters Technology Notes:
- Relative Binding Affinities of Integrin Antagonists by Equilibrium Dialysis and Liquid Chromatography–Mass Spectrometry by William J. Tipping, Nkazimulo Tshuma, James Adams, Harvey T. Haywood, James E. Rowedder, M. Jonathan Fray, Thomas McInally, Simon J. F. Macdonald, and Neil J. Oldham
- Preparative Microfluidic Electrosynthesis of Drug Metabolites by Romain Stalder and Gregory P. Roth
- Trifluoromethyl Fluorocoxib A Detects Cyclooxygenase-2 Expression in Inflammatory Tissues and Human Tumor Xenografts by Md. Jashim Uddin, Brenda C. Crews, Imran Huda, Kebreab Ghebreselasie, Cristina K. Daniel, and Lawrence J. Marnett
- A Fluorescence Polarization Biophysical Assay for the Naegleria DNA Hydroxylase Tet1 by Laura J. Marholz, Wei Wang, Yu Zheng, and Xiang Wang
- EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides by Gilles H. Goetz, Laurence Philippe, and Michael J. Shapiro
- High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma by Christine E. Quartararo, Eduard Reznik, Ana C. deCarvalho, Tom Mikkelsen, and Brent R. Stockwell
Read the entire Virtual Issue “Technological Advances in Medicinal Chemistry.”
Med Chem Tech Call for Papers
The goal of the upcoming special issue “Med Chem Tech: Driving Drug Development” is to go beyond that virtual issue and expand the literature on medicinal chemistry technology to include the most up-to-date technological innovations in medicinal chemistry and drug discovery, say Djuric and Vasudevan.
They enthusiastically invite you to submit papers on a variety of related medicinal chemistry technology topics, including, but not limited to:
- Advances in compound design strategies
- Computational chemistry, including improved free-energy calculations
- The application of artificial intelligence to medicinal chemistry, including SAR development
- Advances in fragment-based chemistry
- Chemical biology, including approaches to targeted protein degradation and target-engagement assessment
- Automated chemistry with robotics
- Integrated synthesis
- Bioassay systems
If you have questions about submitting your research to this special issue on medicinal chemistry technology, please email Stevan W. Djuric at email@example.com and Anil Vasudevan at firstname.lastname@example.org.
Submit your research for inclusion in “Med Chem Tech: Driving Drug Development” by February 15, 2018.