We’ve compiled lists of the five most-read articles that appeared in each ACS Publications biological chemistry journal in 2017, including research, reviews, perspectives and editorial pieces.
There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention over the past year.
Read more of 2017’s most-read articles: Analytical | Applied | Materials Science & Engineering | Multidisciplinary | Organic/Inorganic | Physical
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ACS Biomaterials Science & Engineering
Metal-Chelation-Assisted Deposition of Polydopamine on Human Hair: A Ready-to-Use Eumelanin-Based Hair Dyeing Methodology
ACS Biomater. Sci. Eng., 2017, 3 (4), pp 628–636
DOI: 10.1021/acsbiomaterials.7b00031
Surface Analysis of Nanocomplexes by X-ray Photoelectron Spectroscopy (XPS)
Open access through Editors’ Choice
ACS Biomater. Sci. Eng., 2017, 3 (6), pp 882–889
DOI: 10.1021/acsbiomaterials.7b00040
Preparation of Biodegradable Cationic Polycarbonates and Hydrogels through the Direct Polymerization of Quaternized Cyclic Carbonates
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ACS Biomater. Sci. Eng., 2017, 3 (8), pp 1567–1575
DOI: 10.1021/acsbiomaterials.7b00335
Bioconjugation of Gold Nanobipyramids for SERS Detection and Targeted Photothermal Therapy in Breast Cancer
Open access through Editors’ Choice
ACS Biomater. Sci. Eng., 2017, 3 (4), pp 608–618
DOI: 10.1021/acsbiomaterials.7b00021
3D Printing of a Double Network Hydrogel with a Compression Strength and Elastic Modulus Greater than those of Cartilage
ACS Biomater. Sci. Eng., 2017, 3 (5), pp 863–869
DOI: 10.1021/acsbiomaterials.7b00094
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ACS Catalysis
Catalysis by Supported Single Metal Atoms
ACS Catal., 2017, 7 (1), pp 34–59
DOI: 10.1021/acscatal.6b01534
Rational Design of High-Performance Phosphine Sulfonate Nickel Catalysts for Ethylene Polymerization and Copolymerization with Polar Monomers
Open access through ACS AuthorChoice
ACS Catal., 2017, 7 (2), pp 1308–1312
DOI: 10.1021/acscatal.6b03394
Superlative Scientific Writing
ACS Catal., 2017, 7 (3), pp 2218–2219
DOI: 10.1021/acscatal.7b00566
Kinetic Modeling of the Nickel-Catalyzed Esterification of Amides
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ACS Catal., 2017, 7 (7), pp 4381–4385
DOI: 10.1021/acscatal.7b01444
Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins
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ACS Catal., 2017, 7 (2), pp 1432–1437
DOI: 10.1021/acscatal.6b03388
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ACS Chemical Biology
Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy
ACS Chem. Biol., 2017, 12 (4), pp 892–898
DOI: 10.1021/acschembio.6b01068
Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation
ACS Chem. Biol., 2017, 12 (10), pp 2570–2578
DOI: 10.1021/acschembio.7b00485
Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases
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ACS Chem. Biol., 2017, 12 (3), pp 852–861
DOI: 10.1021/acschembio.6b01052
Enzyme That Makes You Cry–Crystal Structure of Lachrymatory Factor Synthase from Allium cepa
ACS Chem. Biol., 2017, 12 (9), pp 2296–2304
DOI: 10.1021/acschembio.7b00336
Ionic Strength Sensing in Living Cells
Open access through ACS AuthorChoice
ACS Chem. Biol., 2017, 12 (10), pp 2510–2514
DOI: 10.1021/acschembio.7b00348
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ACS Chemical Neuroscience
Hitchhiker’s Guide to Voltammetry: Acute and Chronic Electrodes for in Vivo Fast-Scan Cyclic Voltammetry
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ACS Chem. Neurosci., 2017, 8 (2), pp 221–234
DOI: 10.1021/acschemneuro.6b00393
Chronic Traumatic Encephalopathy (CTE): A Brief Historical Overview and Recent Focus on NFL Players
ACS Chem. Neurosci., 2017, 8 (8), pp 1629–1631
DOI: 10.1021/acschemneuro.7b00291
Call for Papers: DARK Classics in Chemical Neuroscience
ACS Chem. Neurosci., 2017, 8 (9), pp 1812–1812
DOI: 10.1021/acschemneuro.7b00306
Why Is Research on Amyloid-β Failing to Give New Drugs for Alzheimer’s Disease?
ACS Chem. Neurosci., 2017, 8 (7), pp 1435–1437
DOI: 10.1021/acschemneuro.7b00188
The Striosome and Matrix Compartments of the Striatum: A Path through the Labyrinth from Neurochemistry toward Function
Open access through ACS AuthorChoice
ACS Chem. Neurosci., 2017, 8 (2), pp 235–242
DOI: 10.1021/acschemneuro.6b00333
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ACS Infectious Diseases
Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus
Open access through Editors’ Choice
ACS Infect. Dis., 2017, 3 (8), pp 595–605
DOI: 10.1021/acsinfecdis.7b00064
Hydrophilic Phage-Mimicking Membrane Active Antimicrobials Reveal Nanostructure-Dependent Activity and Selectivity
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ACS Infect. Dis., 2017, 3 (9), pp 676–687
DOI: 10.1021/acsinfecdis.7b00076
Discovery of a Novel Nitric Oxide Binding Protein and Nitric-Oxide-Responsive Signaling Pathway in Pseudomonas aeruginosa
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ACS Infect. Dis., 2017, 3 (6), pp 454–461
DOI: 10.1021/acsinfecdis.7b00027
Rational Design of Single-Chain Polymeric Nanoparticles That Kill Planktonic and Biofilm Bacteria
ACS Infect. Dis., 2017, 3 (3), pp 237–248
DOI: 10.1021/acsinfecdis.6b00203
Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells
ACS Infect. Dis., 2017, 3 (9), pp 634–644
DOI: 10.1021/acsinfecdis.7b00028
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INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology
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ACS Med. Chem. Lett., 2017, 8 (5), pp 486–491
DOI: 10.1021/acsmedchemlett.6b00391
Medicinal Chemistry: Where Are All the Women?
ACS Med. Chem. Lett., 2017, 8 (9), pp 900–902
DOI: 10.1021/acsmedchemlett.7b00321
Practical High-Throughput Experimentation for Chemists
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ACS Med. Chem. Lett., 2017, 8 (6), pp 601–607
DOI: 10.1021/acsmedchemlett.7b00165
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
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ACS Med. Chem. Lett., 2017, 8 (3), pp 321–326
DOI: 10.1021/acsmedchemlett.6b00491
Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties
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ACS Med. Chem. Lett., 2017, 8 (6), pp 608–613
DOI: 10.1021/acsmedchemlett.7b00103
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ACS Synthetic Biology
A Straightforward Approach for 3D Bacterial Printing
Open access through ACS AuthorChoice
ACS Synth. Biol., 2017, 6 (7), pp 1124–1130
DOI: 10.1021/acssynbio.6b00395
Programmable DNA-Guided Artificial Restriction Enzymes
ACS Synth. Biol., 2017, 6 (5), pp 752–757
DOI: 10.1021/acssynbio.6b00324
Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis
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ACS Synth. Biol., 2017, 6 (5), pp 884–890
DOI: 10.1021/acssynbio.6b00372
Extracellular Self-Assembly of Functional and Tunable Protein Conjugates from Bacillus subtilis
Open access through ACS AuthorChoice
ACS Synth. Biol., 2017, 6 (6), pp 957–967
DOI: 10.1021/acssynbio.6b00292
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Biochemistry
Residue-Specific Peptide Modification: A Chemist’s Guide
Biochemistry, 2017, 56 (30), pp 3863–3873
DOI: 10.1021/acs.biochem.7b00536
It Is Chemistry but Not Your Grandfather’s Chemistry
Biochemistry, 2017, 56 (1), pp 1–2
DOI: 10.1021/acs.biochem.6b01262
The Cation−π Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification
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Biochemistry, 2017, 56 (11), pp 1585–1595
DOI: 10.1021/acs.biochem.7b00056
Identification of Microprotein–Protein Interactions via APEX Tagging
Open access through Editors’ Choice
Biochemistry, 2017, 56 (26), pp 3299–3306
DOI: 10.1021/acs.biochem.7b00265
Structure–Energy Relationships of Halogen Bonds in Proteins
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Biochemistry, 2017, 56 (22), pp 2794–2802
DOI: 10.1021/acs.biochem.7b00022
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In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges
Bioconjugate Chem., 2017, 28 (4), pp 880–884
DOI: 10.1021/acs.bioconjchem.7b00057
Site-Specific Dual Functionalization of Cysteine Residue in Peptides and Proteins with 2-Azidoacrylates
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Bioconjugate Chem., 2017, 28 (4), pp 897–902
DOI: 10.1021/acs.bioconjchem.7b00024
89Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89Zr Radiochemistry
Open access through ACS AuthorChoice
Bioconjugate Chem., 2017, 28 (9), pp 2211–2223
DOI: 10.1021/acs.bioconjchem.7b00325
Versatile Site-Selective Protein Reaction Guided by WW Domain–Peptide Motif Interaction
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Bioconjugate Chem., 2017, 28 (8), pp 2199–2205
DOI: 10.1021/acs.bioconjchem.7b00334
Biointerfacing and Applications of Cell Membrane-Coated Nanoparticles
This article is part of the Interfacing Inorganic Nanoparticles with Biology special issue.
Bioconjugate Chem., 2017, 28 (1), pp 23–32
DOI: 10.1021/acs.bioconjchem.6b00569
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Biomacromolecules
Hydrogels for Therapeutic Delivery: Current Developments and Future Directions
Open access through ACS AuthorChoice
Biomacromolecules, 2017, 18 (2), pp 316–330
DOI: 10.1021/acs.biomac.6b01604
Stimuli-Responsive Polymersomes for Biomedical Applications
Biomacromolecules, 2017, 18 (3), pp 649–673
DOI: 10.1021/acs.biomac.6b01704
Recent Developments in the Synthesis of Biomacromolecules and their Conjugates by Single Electron Transfer–Living Radical Polymerization
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Biomacromolecules, 2017, 18 (4), pp 1039–1063
DOI: 10.1021/acs.biomac.7b00197
Degradable Adhesives for Surgery and Tissue Engineering
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Biomacromolecules, 2017, 18 (10), pp 3009–3039
DOI: 10.1021/acs.biomac.7b00969
Injectable and 3D Bioprinted Polysaccharide Hydrogels: From Cartilage to Osteochondral Tissue Engineering
Biomacromolecules, 2017, 18 (1), pp 1–26
DOI: 10.1021/acs.biomac.6b01619
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Journal of Agricultural and Food Chemistry
Control of Maillard Reactions in Foods: Strategies and Chemical Mechanisms
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J. Agric. Food Chem., 2017, 65 (23), pp 4537–4552
DOI: 10.1021/acs.jafc.7b00882
Rare Sugar Syrup Containing d-Allulose but Not High-Fructose Corn Syrup Maintains Glucose Tolerance and Insulin Sensitivity Partly via Hepatic Glucokinase Translocation in Wistar Rats
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J. Agric. Food Chem., 2017, 65 (13), pp 2888–2894
DOI: 10.1021/acs.jafc.6b05627
Development of a QuEChERS-Based Method for the Simultaneous Determination of Acidic Pesticides, Their Esters, and Conjugates Following Alkaline Hydrolysis
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J. Agric. Food Chem., 2017, 65 (6), pp 1296–1305
DOI: 10.1021/acs.jafc.6b05407
Novel trans-Ferulic Acid Derivatives Containing a Chalcone Moiety as Potential Activator for Plant Resistance Induction
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J. Agric. Food Chem., 2017, 65 (22), pp 4367–4377
DOI: 10.1021/acs.jafc.7b00958
An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice
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J. Agric. Food Chem., 2017, 65 (43), pp 9435–9442
DOI: 10.1021/acs.jafc.7b02979
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Journal of Chemical Theory and Computation
An Ab Initio Exciton Model Including Charge-Transfer Excited States
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J. Chem. Theory Comput., 2017, 13 (8), pp 3493–3504
DOI: 10.1021/acs.jctc.7b00171
A Robust and Accurate Tight-Binding Quantum Chemical Method for Structures, Vibrational Frequencies, and Noncovalent Interactions of Large Molecular Systems Parametrized for All spd-Block Elements (Z = 1–86)
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (5), pp 1989–2009
DOI: 10.1021/acs.jctc.7b00118
Machine Learning Force Field Parameters from Ab Initio Data
J. Chem. Theory Comput., 2017, 13 (9), pp 4492–4503
DOI: 10.1021/acs.jctc.7b00521
Psi4 1.1: An Open-Source Electronic Structure Program Emphasizing Automation, Advanced Libraries, and Interoperability
J. Chem. Theory Comput., 2017, 13 (7), pp 3185–3197
DOI: 10.1021/acs.jctc.7b00174
Cheap and Near Exact CASSCF with Large Active Spaces
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J. Chem. Theory Comput., 2017, 13 (11), pp 5468–5478
DOI: 10.1021/acs.jctc.7b00900
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Journal of Medicinal Chemistry
The Essential Medicinal Chemistry of Curcumin
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J. Med. Chem., 2017, 60 (5), pp 1620–1637
DOI: 10.1021/acs.jmedchem.6b00975
Synthetic Approaches to the New Drugs Approved During 2015
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J. Med. Chem., 2017, 60 (15), pp 6480–6515
DOI: 10.1021/acs.jmedchem.7b00010
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
J. Med. Chem., 2017, 60 (4), pp 1247–1261
DOI: 10.1021/acs.jmedchem.6b01751
A Versatile Method to Determine the Cellular Bioavailability of Small-Molecule Inhibitors
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J. Med. Chem., 2017, 60 (1), pp 157–169
DOI: 10.1021/acs.jmedchem.6b00923
How Big Is Too Big for Cell Permeability?
J. Med. Chem., 2017, 60 (5), pp 1662–1664
DOI: 10.1021/acs.jmedchem.7b00237
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Journal of Natural Products
Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community
Open access through ACS AuthorChoice
J. Nat. Prod., 2017, 80 (3), pp 756–770
DOI: 10.1021/acs.jnatprod.6b01085
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects
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J. Nat. Prod., 2017, 80 (3), pp 740–755
DOI: 10.1021/acs.jnatprod.6b00970
The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture
J. Nat. Prod., 2017, 80 (4), pp 1150–1160
DOI: 10.1021/acs.jnatprod.7b00133
Bioinspired Indole Prenylation Reactions in Water
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J. Nat. Prod., 2017, 80 (8), pp 2371–2378
DOI: 10.1021/acs.jnatprod.7b00464
Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors
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J. Nat. Prod., 2017, 80 (3), pp 692–698
DOI: 10.1021/acs.jnatprod.6b01006
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The Journal of Physical Chemistry B
The Hydrophobic Effect and the Role of Cosolvents
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J. Phys. Chem. B, 2017, 121 (43), pp 9986–9998
DOI: 10.1021/acs.jpcb.7b06453
Crowding in Cellular Environments at an Atomistic Level from Computer Simulations
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J. Phys. Chem. B, 2017, 121 (34), pp 8009–8025
DOI: 10.1021/acs.jpcb.7b03570
Beyond the Hofmeister Series: Ion-Specific Effects on Proteins and Their Biological Functions
J. Phys. Chem. B, 2017, 121 (9), pp 1997–2014
DOI: 10.1021/acs.jpcb.6b10797
Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein
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J. Phys. Chem. B, 2017, 121 (9), pp 2049–2061
DOI: 10.1021/acs.jpcb.6b11976
Virtual Issue in Honor of the 150th Birthday of Marie Curie: Highlighting Female Physical Chemists
J. Phys. Chem. B, 2017, 121 (43), pp 9983–9985
DOI: 10.1021/acs.jpcb.7b09653
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The Journal of Physical Chemistry Letters
Cs2InAgCl6: A New Lead-Free Halide Double Perovskite with Direct Band Gap
J. Phys. Chem. Lett., 2017, 8 (4), pp 772–778
DOI: 10.1021/acs.jpclett.6b02682
Charge Carrier Trapping at Surface Defects of Perovskite Solar Cell Absorbers: A First-Principles Study
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J. Phys. Chem. Lett., 2017, 8 (4), pp 742–746
DOI: 10.1021/acs.jpclett.7b00055
Photoresponse of CsPbBr3 and Cs4PbBr6 Perovskite Single Crystals
J. Phys. Chem. Lett., 2017, 8 (3), pp 565–570
DOI: 10.1021/acs.jpclett.6b02763
High-Quality (CH3NH3)3Bi2I9 Film-Based Solar Cells: Pushing Efficiency up to 1.64%
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J. Phys. Chem. Lett., 2017, 8 (17), pp 4300–4307
DOI: 10.1021/acs.jpclett.7b01952
Hydrogen-Mediated Electron Doping of Gold Clusters As Revealed by In Situ X-ray and UV–vis Absorption Spectroscopy
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J. Phys. Chem. Lett., 2017, 8 (11), pp 2368–2372
DOI: 10.1021/acs.jpclett.7b00722
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Journal of Proteome Research
Discovery of Novel Antimicrobial Peptides from Varanus komodoensis (Komodo Dragon) by Large-Scale Analyses and De-Novo-Assisted Sequencing Using Electron-Transfer Dissociation Mass Spectrometry
J. Proteome Res., 2017, 16 (4), pp 1470–1482
DOI: 10.1021/acs.jproteome.6b00857
MHC-I Ligand Discovery Using Targeted Database Searches of Mass Spectrometry Data: Implications for T-Cell Immunotherapies
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J. Proteome Res., 2017, 16 (4), pp 1806–1816
DOI: 10.1021/acs.jproteome.6b00971
Global Post-Translational Modification Discovery
Open access through ACS AuthorChoice
J. Proteome Res., 2017, 16 (4), pp 1383–1390
DOI: 10.1021/acs.jproteome.6b00034
Assessment of Label-Free Quantification in Discovery Proteomics and Impact of Technological Factors and Natural Variability of Protein Abundance
Open access through ACS AuthorChoice
J. Proteome Res., 2017, 16 (4), pp 1410–1424
DOI: 10.1021/acs.jproteome.6b00645
Quantitative Analysis of Human Red Blood Cell Proteome
Open access through ACS AuthorChoice
J. Proteome Res., 2017, 16 (8), pp 2752–2761
DOI: 10.1021/acs.jproteome.7b00025
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Molecular Pharmaceutics
Lipid–Drug Conjugate for Enhancing Drug Delivery
This article is part of the Bioconjugate Therapeutics special issue.
Mol. Pharmaceutics, 2017, 14 (5), pp 1325–1338
DOI: 10.1021/acs.molpharmaceut.6b01027
Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance
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Mol. Pharmaceutics, 2017, 14 (5), pp 1623–1633
DOI: 10.1021/acs.molpharmaceut.6b01091
Encapsulation of Ibuprofen in CD-MOF and Related Bioavailability Studies
Mol. Pharmaceutics, 2017, 14 (5), pp 1831–1839
DOI: 10.1021/acs.molpharmaceut.7b00168
Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine
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Mol. Pharmaceutics, 2017, 14 (7), pp 2245–2253
DOI: 10.1021/acs.molpharmaceut.7b00076
Biocompatible Injectable Hydrogel with Potent Wound Healing and Antibacterial Properties
Mol. Pharmaceutics, 2017, 14 (4), pp 1218–1230
DOI: 10.1021/acs.molpharmaceut.6b01104
