ACS Editors’ Choice: Dengue Virus, Drugs Based on Natural Products, and Arsenic in Groundwater - ACS Axial | ACS Publications

ACS Editors’ Choice: Dengue Virus, Drugs Based on Natural Products, and Arsenic in Groundwater

This week: The medicinal chemistry of dengue virus, natural products as sources for new drugs, dramatic seasonal shifts in groundwater arsenic– and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!

 Selective Imaging of Malignant Ascites in a Mouse Model of Peritoneal Metastasis Using in Vivo Dynamic Nuclear Polarization-Magnetic Resonance Imaging


Hinako Eto, Fuminori Hyodo, Kenji Nakano, and Hideo Utsumi

Anal. Chem., Article ASAP

DOI: 10.1021/acs.analchem.5b04821


Natural Products as Sources of New Drugs from 1981 to 2014


David J. Newman and Gordon M. Cragg

Nat. Prod., Article ASAP

DOI: 10.1021/acs.jnatprod.5b01055


Soluble Dinaphtho[2,3-b:2′,3′-f]thieno[3,2-b]thiophene Derivatives for Solution-Processed Organic Field-Effect Transistors

Masanori SawamotoMyeong Jin KangEigo MiyazakiHiroyoshi SuginoItaru Osaka, and Kazuo Takimiya

ACS Appl. Mater. Interfaces, Article ASAP

DOI: 10.1021/acsami.5b10477


Aquifer Arsenic Cycling Induced by Seasonal Hydrologic Changes within the Yangtze River Basin

Michael V. Schaefer, Samantha C. Ying, Shawn G. Benner, Yanhua Duan, Yanxin Wang, and Scott Fendorf

Environ. Sci. Technol., Article ASAP

DOI: 10.1021/acs.est.5b04986


Discovery of 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8H-purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma

Keith Biggadike, Mahbub Ahmed, Doug I. Ball, Diane M. Coe, Deidre A. Dalmas Wilk, Chris D. Edwards, Bob H. Gibbon, Charlotte J. Hardy, Stephen A. Hermitage, Joanne O. Hessey, Aimee E. Hillegas, Stephen C. Hughes, Linos Lazarides, Xiao Q. Lewell, Amanda Lucas, David N. Mallett, Mark A. Price, Fiona M. Priest, Diana J. Quint, Poonam Shah, Anesh Sitaram, Stephen A. Smith, Richard Stocker, Naimisha A. Trivedi, Daphne C. Tsitoura, and Victoria Weller

Med. Chem., Article ASAP

DOI: 10.1021/acs.jmedchem.5b01647


Highly Regio- and Enantioselective Hydroformylation of Vinyl Esters Using Bidentate Phosphine,P-Chiral Phosphorodiamidite Ligands

Christian Schmitz, Katharina Holthusen, Walter Leitner, and Giancarlo Franciò

ACS Catal., 2016, 6, pp 1584–1589

DOI: 10.1021/acscatal.5b02846


The Medicinal Chemistry of Dengue Virus


Mira A. M. Behnam, Christoph Nitsche, Veaceslav Boldescu, and Christian D. Klein

Med. Chem., Article ASAP

DOI: 10.1021/acs.jmedchem.5b01653


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