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ACS Editors’ Choice: The Return of Phenotypic Assessment in Drug Discovery

This week: phenotypic assessment in drug discovery, a review of hydrophobic interactions, the nature of anisotropic polymer interfaces — and more!

Each and every day, ACS grants free access to a new peer-reviewed research article from one of the Society’s journals. These articles are specially chosen by a team of scientific editors of ACS journals from around the world to highlight the transformative power of chemistry. Access to these articles will remain open to all as a public service.

Check out this week’s picks!
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Phenotypic Assessment and the Discovery of Topiramate
ml-2016-00176u_0002
ACS Med. Chem. Lett., Article ASAP
DOI: 10.1021/acsmedchemlett.6b00176
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Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa
ol-2016-009793_0006
Org. Lett., 2016, 18 (11), pp 2596–2599
DOI: 10.1021/acs.orglett.6b00979
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Polymer Interfaces: Synthetic Strategies Enabling Functionality, Adaptivity, and Spatial Control
ma-2016-00650d_0014
Macromolecules, Article ASAP
DOI: 10.1021/acs.macromol.6b00650
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Statistical Analyses of Hydrophobic Interactions: A Mini-Review
jp-2016-040825_0013
J. Phys. Chem. B, Article ASAP
DOI: 10.1021/acs.jpcb.6b04082
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The Proximal Lilly Collection: Mapping, Exploring and Exploiting Feasible Chemical Space
ci-2016-00173m_0014
J. Chem. Inf. Model., Article ASAP
DOI: 10.1021/acs.jcim.6b00173
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Suppressing the Rayleigh–Plateau Instability in Field-Directed Colloidal Assembly
la-2016-007713_0009
Langmuir, Article ASAP
DOI: 10.1021/acs.langmuir.6b00771
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Harmonics Generation by Surface Plasmon Polaritons on Single Nanowires
ph-2015-00686c_0006
ACS Photonics, Article ASAP
DOI: 10.1021/acsphotonics.5b00686
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