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Georg and her group are involved in the design, semisynthesis, total synthesis, and evaluation of biologically active agents. Current therapeutic areas include cancer, male contraception, epilepsy, and Alzheimer’s disease. These projects require the development of synthetic methods, synthesis of natural products, and structure-activity studies aimed at improving the therapeutic efficacy of lead compounds, including natural products, and hits from high throughput screening.
She holds the Robert Vince Endowed Chair and McKnight Presidential Chair and directs its Institute for Therapeutics Discovery & Development, which she established. She serves on the editorial advisory boards of ACS Medicinal Chemistry Letters and the Journal of Organic Chemistry.
Her awards include the 2008 Distinguished Medicinal Chemistry Lectureship in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, the 2005 Loyd E. Harris Lecture, School of Pharmacy, University of Oklahoma, and the 2005 George Lesher Lecture in Bioorganic and Medicinal Chemistry, Department of Chemistry, Rensselear Polytechnic Institute.