Read Impactful Research Highlights from ACS Chemical Neuroscience

ACS Chemical Neuroscience publishes high-quality research articles and reviews that showcase chemical, quantitative biological, biophysical and bioengineering approaches to the understanding of the nervous system and to the development of new treatments for neurological disorders.

Explore a selection of the journal’s top-cited articles, including reviews, original research, and special and virtual issues covering topical subjects:


Are Dopamine Oxidation Metabolites Involved in the Loss of Dopaminergic Neurons in the Nigrostriatal System in Parkinson’s Disease?
ACS Chem. Neurosci., 2017, 8 (4), pp 702–711
DOI: 10.1021/acschemneuro.7b00034

From the Neuroinflammation Special Issue:

From the Serotonin Research 2016 Special Issue:

  • The Rodent Forced Swim Test Measures Stress-Coping Strategy, Not Depression-like Behavior
    ACS Chem. Neurosci., 2017, 8 (5), pp 955–960
    DOI: 10.1021/acschemneuro.7b00042

From the Classics in Chemical Neuroscience Virtual Issue

From the Monitoring Molecules in Neuroscience Special Issue:

  • Hitchhiker’s Guide to Voltammetry: Acute and Chronic Electrodes for in Vivo Fast-Scan Cyclic Voltammetry
    ACS Chem. Neurosci., 2017, 8 (2), pp 221–234
    DOI: 10.1021/acschemneuro.6b00393

Research Articles

Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery
ACS Chem. Neurosci., 2016, 7 (6), pp 767–775
DOI: 10.1021/acschemneuro.6b00029

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues
ACS Chem. Neurosci., 2016, 7 (9), pp 1241–1254
DOI: 10.1021/acschemneuro.6b00137

Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation Pathway
ACS Chem. Neurosci., 2016, 7 (1), pp 56–68
DOI: 10.1021/acschemneuro.5b00214

Alzheimer’s Protective Cross-Interaction between Wild-Type and A2T Variants Alters
ACS Chem. Neurosci., 2017, 8 (3), pp 606–618
DOI: 10.1021/acschemneuro.6b00357

Metabolism and Distribution of Clozapine-N-oxide: Implications for Nonhuman Primate Chemogenetics
ACS Chem. Neurosci., 2017, 8 (7), pp 1570–1576
DOI: 10.1021/acschemneuro.7b00079

Discover more must-read research in ACS Chemical Neuroscience today:



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