There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five […]

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in August 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

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Read more of August’s most-read articles.

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On-DNA Decarboxylative Arylation: Merging Photoredox with Nickel Catalysis in Water
DOI: 10.1021/acscombsci.9b00076

High-Affinity α5β1-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries
DOI: 10.1021/acscombsci.9b00081

Multicomponent Synthesis of Diversified Chromeno[3,2-d]oxazoles
DOI: 10.1021/acscombsci.9b00084

Plasmonic Selection of ssDNA Aptamers against Fibroblast Growth Factor Receptor
DOI: 10.1021/acscombsci.9b00059

Encrypted Oligonucleotide Arrays for Molecular Authentication
DOI: 10.1021/acscombsci.9b00088

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3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
DOI: 10.1021/acs.jmedchem.9b00719

Synthetic Approaches to the New Drugs Approved During 2017
DOI: 10.1021/acs.jmedchem.9b00196

Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway
DOI: 10.1021/acs.jmedchem.9b00348

Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways
DOI: 10.1021/acs.jmedchem.9b00030

Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity
DOI: 10.1021/acs.jmedchem.9b00516

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Inverse Electron Demand Diels–Alder Reactions of Heterocyclic Azadienes, 1-Aza-1,3-Butadienes, Cyclopropenone Ketals, and Related Systems. A Retrospective
DOI: 10.1021/acs.joc.9b00834

Nickel(II)-Catalyzed [5 + 1] Annulation of 2-Carbonyl-1-propargylindoles with Hydroxylamine To Synthesize Pyrazino[1,2-a]indole-2-oxides in Water
DOI: 10.1021/acs.joc.9b00784

Generation of Aryl Radicals from Aryl Halides: Rongalite-Promoted Transition-Metal-Free Arylation
DOI: 10.1021/acs.joc.9b01113

Perylene Bisimide Dyes with up to Five Independently Introduced Substituents: Controlling the Functionalization Pattern and Photophysical Properties Using Regiospecific Bay Substitution
DOI: 10.1021/acs.joc.9b01131

Visible Light-Promoted Photocatalytic C-5 Carboxylation of 8-Aminoquinoline Amides and Sulfonamides via a Single Electron Transfer Pathway
DOI: 10.1021/acs.joc.9b00942

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