There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in August 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.
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Read more of August’s most-read articles.
ACS Catalysis
The 2018 Journal Impact Factor for ACS Catalysis
DOI: 10.1021/acscatal.9b03106
A Method for Assessing Catalyst Deactivation: A Case Study on Methanol-to-Hydrocarbons Conversion
DOI: 10.1021/acscatal.9b01106
Enantioselective Electroreductive Coupling of Alkenyl and Benzyl Halides via Nickel Catalysis
DOI: 10.1021/acscatal.9b01785
Electrochemical Reduction of CO2 on Metal-Nitrogen-Doped Carbon Catalysts
DOI: 10.1021/acscatal.9b01405
Identification of FeN4 as an Efficient Active Site for Electrochemical N2 Reduction
DOI: 10.1021/acscatal.9b00959
ACS Combinatorial Science
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On-DNA Decarboxylative Arylation: Merging Photoredox with Nickel Catalysis in Water
DOI: 10.1021/acscombsci.9b00076
High-Affinity α5β1-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries
DOI: 10.1021/acscombsci.9b00081
Multicomponent Synthesis of Diversified Chromeno[3,2-d]oxazoles
DOI: 10.1021/acscombsci.9b00084
Plasmonic Selection of ssDNA Aptamers against Fibroblast Growth Factor Receptor
DOI: 10.1021/acscombsci.9b00059
Encrypted Oligonucleotide Arrays for Molecular Authentication
DOI: 10.1021/acscombsci.9b00088
ACS Medicinal Chemistry Letters
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Treatment of Cancer and Alzheimer’s Disease by PROTAC Degradation of EGFR
DOI: 10.1021/acsmedchemlett.9b00283
Lowering Lipophilicity by Adding Carbon: AzaSpiroHeptanes, a logD Lowering Twist
DOI: 10.1021/acsmedchemlett.9b00248
PROTACs and Targeted Protein Degradation for Treating ALK-Mediated Cancers
DOI: 10.1021/acsmedchemlett.9b00296
Quick Building Blocks (QBB): An Innovative and Efficient Business Model To Speed Medicinal Chemistry Analog Synthesis
DOI: 10.1021/acsmedchemlett.9b00205
In Praise of Remarkably Powerful Centamolecular Therapeutic Agents
DOI: 10.1021/acsmedchemlett.9b00286
Bioconjugate Chemistry
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Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection
DOI: 10.1021/acs.bioconjchem.9b00403
Cell-Penetrating Peptide Enhanced Antigen Presentation for Cancer Immunotherapy
DOI: 10.1021/acs.bioconjchem.9b00245
Site-Specific Incorporation of a Dithiolane Containing Amino Acid into Proteins
DOI: 10.1021/acs.bioconjchem.9b00413
Recent Advances of Molecular Optical Probes in Imaging of β-Galactosidase
DOI: 10.1021/acs.bioconjchem.9b00391
Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis
DOI: 10.1021/acs.bioconjchem.9b00447
Inorganic Chemistry
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What IS Inorganic Chemistry?
DOI: 10.1021/acs.inorgchem.9b02015
Inorganic Young Investigators: A Celebration for Our Rising Stars
DOI: 10.1021/acs.inorgchem.9b02249
Celebrating the Year of the Periodic Table: Emerging Investigators in Inorganic Chemistry
DOI: 10.1021/acs.inorgchem.9b02174
Metal–Oxyl Species and Their Possible Roles in Chemical Oxidations
DOI: 10.1021/acs.inorgchem.8b03459
Observations on the Mechanochemical Insertion of Zinc(II), Copper(II), Magnesium(II), and Select Other Metal(II) Ions into Porphyrins
DOI: 10.1021/acs.inorgchem.9b00052
Journal of Medicinal Chemistry
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3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
DOI: 10.1021/acs.jmedchem.9b00719
Synthetic Approaches to the New Drugs Approved During 2017
DOI: 10.1021/acs.jmedchem.9b00196
Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway
DOI: 10.1021/acs.jmedchem.9b00348
Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways
DOI: 10.1021/acs.jmedchem.9b00030
Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity
DOI: 10.1021/acs.jmedchem.9b00516
Journal of Natural Products
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Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity
DOI: 10.1021/acs.jnatprod.9b00144
Aphidicolin Chemistry of the Deep-Sea-Derived Fungus Botryotinia fuckeliana MCCC 3A00494
DOI: 10.1021/acs.jnatprod.9b00705
Bioactive Sesquiterpene Lactones Isolated from the Whole Plants of Vernonia cinerea
DOI: 10.1021/acs.jnatprod.8b01078
Brominated Azaphilones from the Sponge-Associated Fungus Penicillium canescens Strain 4.14.6a
DOI: 10.1021/acs.jnatprod.9b00151
HPLC-DAD-Directed Isolation of Linearly Fused Prenylated Indole Alkaloids from a Soil-Derived Aspergillus versicolor
DOI: 10.1021/acs.jnatprod.9b00183
The Journal of Organic Chemistry
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Inverse Electron Demand Diels–Alder Reactions of Heterocyclic Azadienes, 1-Aza-1,3-Butadienes, Cyclopropenone Ketals, and Related Systems. A Retrospective
DOI: 10.1021/acs.joc.9b00834
Nickel(II)-Catalyzed [5 + 1] Annulation of 2-Carbonyl-1-propargylindoles with Hydroxylamine To Synthesize Pyrazino[1,2-a]indole-2-oxides in Water
DOI: 10.1021/acs.joc.9b00784
Generation of Aryl Radicals from Aryl Halides: Rongalite-Promoted Transition-Metal-Free Arylation
DOI: 10.1021/acs.joc.9b01113
Perylene Bisimide Dyes with up to Five Independently Introduced Substituents: Controlling the Functionalization Pattern and Photophysical Properties Using Regiospecific Bay Substitution
DOI: 10.1021/acs.joc.9b01131
Visible Light-Promoted Photocatalytic C-5 Carboxylation of 8-Aminoquinoline Amides and Sulfonamides via a Single Electron Transfer Pathway
DOI: 10.1021/acs.joc.9b00942
Molecular Pharmaceutics
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Assessing the Impact of Endogenously Derived Crystalline Drug on the in Vivo Performance of Amorphous Formulations
DOI: 10.1021/acs.molpharmaceut.9b00455
Increasing the Potential of the Auristatin Cancer-Drug Family by Shifting the Conformational Equilibrium
DOI: 10.1021/acs.molpharmaceut.9b00437
Low-Frequency Raman Spectroscopic Study on Compression-Induced Destabilization in Melt-Quenched Amorphous Celecoxib
DOI: 10.1021/acs.molpharmaceut.9b00557
Exosomes: Diagnostic Biomarkers and Therapeutic Delivery Vehicles for Cancer
DOI: 10.1021/acs.molpharmaceut.9b00409
Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins
DOI: 10.1021/acs.molpharmaceut.9b00418
Organic Letters
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Organic Synthesis: Where to from Now? A Personal Perspective from Down Under
DOI: 10.1021/acs.orglett.9b02271
Visible Light-Promoted Aliphatic C–H Arylation Using Selectfluor as a Hydrogen Atom Transfer Reagent
DOI: 10.1021/acs.orglett.9b01635
Arylation of Aldehydes To Directly Form Ketones via Tandem Nickel Catalysis
DOI: 10.1021/acs.orglett.9b01782
COtab: Expedient and Safe Setup for Pd-Catalyzed Carbonylation Chemistry
DOI: 10.1021/acs.orglett.9b01423
Benzaldehyde- and Nickel-Catalyzed Photoredox C(sp3)–H Alkylation/Arylation with Amides and Thioethers
DOI: 10.1021/acs.orglett.9b02226
Organic Process Research & Development
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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.9b00327
The 25th Anniversary of the Buchwald–Hartwig Amination: Development, Applications, and Outlook
DOI: 10.1021/acs.oprd.9b00161
Honoring 25 Years of the Buchwald–Hartwig Amination
DOI: 10.1021/acs.oprd.9b00177
Development and Scale-Up of a Continuous Aerobic Oxidative Chan–Lam Coupling
DOI: 10.1021/acs.oprd.9b00125
Metal-Reductant-Free Electrochemical Nickel-Catalyzed Couplings of Aryl and Alkyl Bromides in Acetonitrile
DOI: 10.1021/acs.oprd.9b00232
Organometallics
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Synthesis and Characterization of (DIPPCCC)Fe Complexes: A Zwitterionic Metalation Method and CO2 Reactivity
DOI: 10.1021/acs.organomet.9b00271
Reactions of Metallacyclopentadiene with Terminal Alkynes: Isolation and Characterization of Metallafulvenallene Complexes
DOI: 10.1021/acs.organomet.9b00371
Sequential Hydrogenation of CO2 to Methanol Using a Pincer Iron Catalyst
DOI: 10.1021/acs.organomet.9b00413
Alkylaluminum Complexes as Precatalysts in Hydroboration of Nitriles and Carbodiimides
DOI: 10.1021/acs.organomet.9b00421
Synthesis of Molybdenum(VI) Neopentylidene Neopentylidyne Complexes
DOI: 10.1021/acs.organomet.9b00412
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