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Discover Cancer Research in ACS Publications Journals

ACS Publications is the most trusted, most cited, most read publisher in chemistry and related sciences. Many ACS Publications journals deal with the intersection of chemistry and biology, including research into cancer treatments. Visit pubs.acs.org to learn more about our entire journal portfolio and click on the journal titles below to learn about each journal’s scope and some of the highlighted cancer research.

ACS Applied Bio Materials

ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.

Nucleic Acid Immunotherapeutics for Cancer
ACS Appl. Bio Mater. 2020, 3, 5, 2838–2849
DOI: 10.1021/acsabm.0c00101

Anti-MUC1/CD44 Dual-Aptamer-Conjugated Liposomes for Cotargeting Breast Cancer Cells and Cancer Stem Cells
ACS Appl. Bio Mater. 2019, 2, 10, 4622–4633
DOI: 10.1021/acsabm.9b00705

Selenium-Containing Carrier-Free Assemblies with Aggregation-Induced Emission Property Combine Cancer Radiotherapy with Chemotherapy
ACS Appl. Bio Mater. 2020, 3, 2, 1283–1292
DOI: 10.1021/acsabm.9b01172

Polymeric Micelles with Reduction-Responsive Function for Targeted Cancer Chemotherapy
ACS Appl. Bio Mater. 2020, 3, 2, 1139–1146
DOI: 10.1021/acsabm.9b01070



ACS Biomaterials Science & Engineering

ACS Biomaterials Science & Engineering publishes high-quality research in the field of biomaterials science & engineering. The journal covers a scope of topics including applications, bio-interactions, bio-compatibility, synthesis & modifications, controlled release & delivery systems, healthcare advances, imaging & diagnostics, manufacturing & technology, modeling & informatics tools, and tissue engineering and regenerative medicine.

Graphene-Induced Transdifferentiation of Cancer Stem Cells as a Therapeutic Strategy against Glioblastoma
ACS Biomater. Sci. Eng. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsbiomaterials.0c00197

Applications of Two-Dimensional Nanomaterials in Breast Cancer Theranostics
ACS Biomater. Sci. Eng. 2020, 6, 4, 1852–1873
DOI: 10.1021/acsbiomaterials.9b01894

Functionalization of Nanomaterials and Their Application in Melanoma Cancer Theranostics
ACS Biomater. Sci. Eng. 2020, 6, 1, 167–181
DOI: 10.1021/acsbiomaterials.9b01426

Cancer Mechanobiology: Microenvironmental Sensing and Metastasis
ACS Biomater. Sci. Eng. 2019, 5, 8, 3735–3752
DOI: 10.1021/acsbiomaterials.8b01230

Wnt/β-Catenin Signaling Pathway Regulates Osteogenesis for Breast Cancer Bone Metastasis: Experiments in an In Vitro Nanoclay Scaffold Cancer Testbed
ACS Biomater. Sci. Eng. 2020, 6, 5, 2600–2611
DOI: 10.1021/acsbiomaterials.9b00923

Graphene-Augmented Nanofiber Scaffolds Trigger Gene Expression Switching of Four Cancer Cell Types
ACS Biomater. Sci. Eng. 2018, 4, 5, 1622–1629
DOI: 10.1021/acsbiomaterials.8b00228



ACS Chemical Biology

ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries.

Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids
ACS Chem. Biol. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acschembio.9b01027

The impact of extracellular fatty acids and oxygen tension on lipid synthesis and assembly in pancreatic cancer cells.
ACS Chem. Biol. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acschembio.0c00219

Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids
ACS Chem. Biol. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acschembio.9b01027

National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library
ACS Chem. Biol. 2020, 15, 4, 1104–1114
DOI: 10.1021/acschembio.0c00139

Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells
ACS Chem. Biol. 2020, 15, 4, 871–877
DOI: 10.1021/acschembio.0c00086

Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides
ACS Chem. Biol. 2020, 15, 3, 774–779
DOI: 10.1021/acschembio.9b01036

C-Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines
ACS Chem. Biol. 2020, 15, 3, 728–739
DOI: 10.1021/acschembio.9b00987

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm
ACS Chem. Biol. 2020, 15, 3, 657–668
DOI: 10.1021/acschembio.9b00748



ACS Chemical Neuroscience

ACS Chemical Neuroscience publishes high-quality research articles and reviews that showcase chemical, quantitative biological, biophysical, and bioengineering approaches to the understanding of the nervous system and to the development of new treatments for neurological disorders. This journal is dedicated to understanding the molecular basis of neurological function in all organisms and model systems.

Promotion of Neuronal Guidance Growth by Aminated Graphene Oxide via Netrin-1/Deleted in Colorectal Cancer Signaling
ACS Chem. Neurosci. 2020, 11, 4, 604–614
DOI: 10.1021/acschemneuro.9b00625

NeuroChat with Professor Kyle Emmitte
ACS Chem. Neurosci. 2020, 11, 2, 99–100
DOI: 10.1021/acschemneuro.9b00582

Association between Parkinson’s Disease and Risk of Cancer: A PRISMA-compliant Meta-analysis
ACS Chem. Neurosci. 2019, 10, 10, 4430–4439
DOI: 10.1021/acschemneuro.9b00498

Discovery of Anticancer Clinical Candidate, Tosedostat, As an Analgesic Agent
ACS Chem. Neurosci. 2019, 10, 9, 4007–4017
DOI: 10.1021/acschemneuro.9b00230

Special Issue on Precision Medicine in Brain Cancer



ACS Medicinal Chemistry Letters
The journal publishes studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules.

Novel Copper Complexes That Inhibit the Proteasome and Trigger Apoptosis in Triple-Negative Breast Cancer Cells
ACS Med. Chem. Lett. 2019, 10, 9, 1328–1335
DOI: 10.1021/acsmedchemlett.9b00284

Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells
ACS Med. Chem. Lett. 2013, 4, 10, 921–926
DOI: 10.1021/ml400093y

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models
ACS Med. Chem. Lett. 2017, 8, 8, 869–874
DOI: 10.1021/acsmedchemlett.7b00220



ACS Nano
Published monthly, ACS Nano is an international forum for the communication of comprehensive articles on nanoscience and nanotechnology research at the interfaces of chemistry, biology, materials science, physics, and engineering.

Peptide-Based Nanoparticles Mimic Fibrillogenesis of Laminin in Tumor Vessels for Precise Embolization
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c02110

Bioresorbable, Miniaturized Porous Silicon Needles on a Flexible Water-Soluble Backing for Unobtrusive, Sustained Delivery of Chemotherapy
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c02343

Perimitochondrial Enzymatic Self-Assembly for Selective Targeting the Mitochondria of Cancer Cells
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c01388

Liver-Targeted siRNA Lipid Nanoparticles Treat Hepatic Cirrhosis by Dual Antifibrotic and Anti-inflammatory Activities
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c02633

Tuning the Brightness and Photostability of Organic Dots for Multivalent Targeted Cancer Imaging and Surgery
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c01034

Reconstructed Apoptotic Bodies as Targeted “Nano Decoys” to Treat Intracellular Bacterial Infections within Macrophages and Cancer Cells
ACS Nano 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsnano.0c00921



ACS Pharmacology & Translational Science
ACS Pharmacology & Translational Science is indexed in PubMed Central® (PMC). Now authors’ work is even more discoverable.

The journal publishes high-quality, innovative research across the broad spectrum of biological sciences—from basic and molecular sciences to translational preclinical studies—including cancer research.

Check out these recent cancer research articles from ACS Pharmacology & Translational Science:

A New Selective Pharmacological Enhancer of the Orai1 Ca2+ Channel Reveals Roles for Orai1 in Smooth and Skeletal Muscle Functions
ACS Pharmacol. Transl. Sci. 2020, 3, 1, 135–147
DOI: 10.1021/acsptsci.9b00081

Auranofin-Based Analogues Are Effective Against Clear Cell Renal Carcinoma In Vivo and Display No Significant Systemic Toxicity
ACS Pharmacol. Transl. Sci. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acsptsci.9b00107

Advances on Tumor-Targeting Delivery of Cytotoxic Proteins
ACS Pharmacol. Transl. Sci. 2020, 3, 1, 107–118
DOI: 10.1021/acsptsci.9b00087

Targeting Functional Activity of AKT Has Efficacy against Aggressive Neuroblastoma
ACS Pharmacol. Transl. Sci. 2020, 3, 1, 148–160
DOI: 10.1021/acsptsci.9b00085

The Emerging Role of Adhesion GPCRs in Cancer
ACS Pharmacol. Transl. Sci. 2020, 3, 1, 29–42
DOI: 10.1021/acsptsci.9b00093



ACS Synthetic Biology

ACS Synthetic Biology is the rapid publication forum for research in synthetic biology & systems bioscience. The journal publishes high-quality research that demonstrates integrative, molecular approaches enabling a better understanding of the organization and function of cells, tissues, and organisms in systems.

A Multifunction Lipid-Based CRISPR-Cas13a Genetic Circuit Delivery System for Bladder Cancer Gene Therapy
ACS Synth. Biol. 2020, 9, 2, 343–355
DOI: 10.1021/acssynbio.9b00349

Protein-Programmed Accumulation of Yeast Cytosine Deaminase in Cancer Cells in Response to Mock-Hypoxia
ACS Synth. Biol. 2019, 8, 5, 948–954
DOI: 10.1021/acssynbio.9b00036

An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics
ACS Synth. Biol. 2019, 8, 10, 2359–2371
DOI: 10.1021/acssynbio.9b00175

Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin–Antitoxin System
ACS Synth. Biol. 2019, 8, 8, 1730–1736
DOI: 10.1021/acssynbio.9b00172

Synthesizing a Genetic Sensor Based on CRISPR-Cas9 for Specifically Killing p53-Deficient Cancer Cells
ACS Synth. Biol. 2018, 7, 7, 1798–1807
DOI: 10.1021/acssynbio.8b00202

Reconstructing Biosynthetic Pathway of the Plant-Derived Cancer Chemopreventive-Precursor Glucoraphanin in Escherichia coli
ACS Synth. Biol. 2018, 7, 1, 121–131
DOI: 10.1021/acssynbio.7b00256



Bioconjugate Chemistry

Bioconjugate Chemistry is the cutting edge forum in conjugation chemistry and biochemistry. This journal invites original contributions on all research at the interface between man-made and biological materials. The mission of the journal is to communicate to advances in fields including therapeutic delivery, imaging, bionanotechnology, and synthetic biology.

Recent Trends in In Situ Enzyme-Activatable Prodrugs for Targeted Cancer Therapy
Bioconjugate Chem. 2020, 31, 4, 1012–1024
DOI: 10.1021/acs.bioconjchem.0c00082

Molecular Imaging for Cancer Immunotherapy: Seeing Is Believing
Bioconjugate Chem. 2020, 31, 2, 404–415
DOI: 10.1021/acs.bioconjchem.9b00851

Zwitterionic Modification of Nanomaterials for Improved Diagnosis of Cancer Cells
Bioconjugate Chem. 2019, 30, 10, 2519–2527
DOI: 10.1021/acs.bioconjchem.9b00543

Porphyrin-Based Nanomedicines for Cancer Treatment
Bioconjugate Chem. 2019, 30, 6, 1585–1603
DOI: 10.1021/acs.bioconjchem.9b00231

Engineering Protein Delivery Depots for Cancer Immunotherapy
Bioconjugate Chem. 2019, 30, 3, 515–524
DOI: 10.1021/acs.bioconjchem.9b00061

Systemic Delivery of Tumor-Targeting siRNA Nanoparticles against an Oncogenic LncRNA Facilitates Effective Triple-Negative Breast Cancer Therapy
Bioconjugate Chem. 2019, 30, 3, 907–919
DOI: 10.1021/acs.bioconjchem.9b00028

Recent Advances in Anti-cancer Protein/Peptide Delivery
Bioconjugate Chem. 2019, 30, 2, 305–324
DOI: 10.1021/acs.bioconjchem.8b00750



Chemical Research in Toxicology

Chemical Research in Toxicology publishes Articles, Rapid Reports, Chemical Profiles, Reviews, Perspectives, Letters to the Editor, and ToxWatch on a wide range of topics in Toxicology that inform a chemical and molecular understanding and capacity to predict biological outcomes on the basis of structures and processes.

Impact of Cancer Therapy-Related Exposures on Late Mortality in Childhood Cancer Survivors
Chem. Res. Toxicol. 2015, 28, 1, 31–37
DOI: 10.1021/tx500374k

Dietary Phytochemicals and Cancer Chemoprevention: A Perspective on Oxidative Stress, Inflammation, and Epigenetics
Chem. Res. Toxicol. 2016, 29, 12, 2071–2095
DOI: 10.1021/acs.chemrestox.6b00413

Targeted Profiling of Heat Shock Proteome in Radioresistant Breast Cancer Cells
Chem. Res. Toxicol. 2019, 32, 2, 326–332
DOI: 10.1021/acs.chemrestox.8b00330



Journal of Medicinal Chemistry
The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.

Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer-Associated Protein 2 (BCA2) as a Treatment for Breast Cancer
J. Med. Chem. 2010, 53, 7, 2757–2765
DOI: 10.1021/jm901757t

Discovery of Salermide-Related Sirtuin Inhibitors: Binding Mode Studies and Antiproliferative Effects in Cancer Cells Including Cancer Stem Cells
J. Med. Chem. 2012, 55, 24, 10937–10947
DOI: 10.1021/jm3011614

Ca2+ Selective Host Rotaxane Is Highly Toxic Against Prostate Cancer Cells
ACS Med. Chem. Lett. 2017, 8, 2, 163–167
DOI: 10.1021/acsmedchemlett.6b00347



Molecular Pharmaceutics
Molecular Pharmaceutics publishes the results of original research that contributes significantly to the molecular mechanistic understanding of drug delivery and drug delivery systems. The journal encourages contributions describing research at the interface of drug discovery and drug development.

Oncolytic Adenoviruses for the Treatment of Human Cancer: Focus on Translational and Clinical Data
Mol. Pharmaceutics 2011, 8, 1, 12–28
DOI: 10.1021/mp100219n

Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells
Mol. Pharmaceutics 2017, 14, 4, 1047–1056
DOI: 10.1021/acs.molpharmaceut.6b00919

Exosomes: Diagnostic Biomarkers and Therapeutic Delivery Vehicles for Cancer
Mol. Pharmaceutics 2019, 16, 8, 3333–3349
DOI: 10.1021/acs.molpharmaceut.9b00409



Nano Letters

Nano Letters is a forum for reporting original results on fundamental, applied, and emerging research in all areas of nanoscience and nanotechnology that require rapid dissemination.

Immunoavidity-Based Capture of Tumor Exosomes Using Poly(amidoamine) Dendrimer Surfaces
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c00950

Nanobowl-Supported Liposomes Improve Drug Loading and Delivery
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c00495

Mimetic Heat Shock Protein Mediated Immune Process to Enhance Cancer Immunotherapy
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c01230

A Carry-On Nitric-Oxide-Luggage for Enhanced Chemotherapeutic Efficacy
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c01532

Copresentation of Tumor Antigens and Costimulatory Molecules via Biomimetic Nanoparticles for Effective Cancer Immunotherapy
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.9b05171

Simultaneous Intravital Optical and Acoustic Monitoring of Ultrasound-Triggered Nanobubble Generation and Extravasation
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c01310

Functional Gadofullerene Nanoparticles Trigger Robust Cancer Immunotherapy Based on Rebuilding an Immunosuppressive Tumor Microenvironment
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c01287

Zwitterionic Nanoconjugate Enables Safe and Efficient Lymphatic Drug Delivery
Nano Lett. 2020, XXXX, XXX, XXX-XXX
DOI: 10.1021/acs.nanolett.0c01713

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