ChemRxiv was first introduced in August 2017 as the premier preprint server for the global chemistry community. Authors using ChemRxiv can submit their research findings for rapid posting on the web and sharing with scientists and colleagues before formal peer review. The first preprint submitted and posted was Excitonics: A universal set of binary gates for molecular exciton processing and signaling. This preprint went on to be peer-reviewed and published in ACS Nano.
In March 2018, the American Chemical Society, the German Chemical Society, and the Royal Society of Chemistry announced a partnership to manage ChemRxiv collaboratively. In August 2019, the Chinese Chemical Society and the Chemical Society of Japan joined the partnership to broaden ChemRxiv’s thriving global presence as a preprint server driven by the chemistry research community.
ChemRxiv: Highlights from the First Four Years
Today, ChemRxiv features nearly 10,000 preprints from authors in 100 countries that have been viewed and downloaded more than 28 million times. Additionally, almost half of these preprints have been peer-reviewed and published in top journals such as the Journal of the American Chemical Society, Angewandte Chemie, Chemical Science, Nature, Science, and more!
Here are the 10 Most Viewed Preprints Posted to ChemRxiv:
COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism
Liu Wenzhong, Li Hualan
Repurposing Therapeutics for COVID-19: Supercomputer-Based Docking to the SARS-CoV-2 Viral Spike Protein and Viral Spike Protein-Human ACE2 Interface
Micholas Smith, Jeremy C. Smith
N-acetyl cysteine: A tool to perturb SARS-CoV-2 spike protein conformation
Utsab Debnath, Amrita Mitra, Varun Dewaker, Yenamandra S. Prabhakar, Raghu Tadala, Kiran Krishnan, Padmakar Wagh, Umashankar Velusamy, Chandru Subramani, Shubhra Agarwal, Sudhanshu Vrati, Aastha Baliyan, Anura V Kurpad, Parthasarathi Bhattacharyya, Amit Mandal
The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination
Christopher G. Jones, Michael W. Martynowycz, Johan Hattne, Tyler J. Fulton, Brian M. Stoltz, Jose A. Rodriguez, Hosea Nelson, Tamir Gonen
Comparing the Respirable Aerosol Concentrations and Particle Size Distributions Generated by Singing, Speaking and Breathing
Florence K. A. Gregson, Natalie A. Watson, Christopher M. Orton, Allen E. Haddrell, Lauren P. McCarthy, Thomas J. R. Finnie, Nick Gent, Gavin C. Donaldson, Pallav L. Shah, James D.Calder, Bryan R. Bzdek, Declan Costello, Jonathan Reid
Potential Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 606 Million Compounds
André Fischer, Manuel Sellner, Santhosh Neranjan, Markus A. Lill, Martin Smieško
Identification of Compounds from Nigella Sativa as New Potential Inhibitors of 2019 Novel Coronavirus (Covid-19): Molecular Docking Study
Salim Bouchentouf, Noureddine Missoum
A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry
Mohamed El-Tholoth, Haim H. Bau, Jinzhao Song
Tripartite combination of potential pandemic mitigation agents: Vitamin D, Quercetin, and Estradiol manifest properties of candidate medicinal agents for mitigation of the severity of pandemic COVID-19 defined by genomics-guided tracing of SARS-CoV-2 targets in human cells.
Whole Genome Sequence Analysis and Homology Modelling of a 3C Like Peptidase and a Non-Structural Protein 3 of the SARS-CoV-2 Shows Protein Ligand Interaction with an Aza-Peptide and a Noncovalent Lead Inhibitor with Possible Antiviral Properties
Arun Shanker, Divya Bhanu, Anjani Alluri, Samriddhi Gupta