We’ve compiled lists of the five most-read analytical chemistry articles that appeared in each ACS Publications journal in December 2017, including research, reviews, perspectives and editorial pieces.

What were chemists reading in December of 2017? To find out, we’ve compiled lists of the five most-read chemistry articles that appeared in each analytical chemistry ACS Publications journal in December 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.

Read More Great December 2017 Chemistry Research:

Applied Chemistry | Biological Chemistry | Materials Science & Engineering | Multidisciplinary Chemistry | Organic/Inorganic Chemistry | Physical Chemistry

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ACS Sensors

DNAzyme Based Nanomachine for in Situ Detection of MicroRNA in Living Cells
ACS Sens., 2017, 2 (12), pp 1847–1853
DOI: 10.1021/acssensors.7b00710

DNAzyme Based Nanomachine for in Situ Detection of MicroRNA in Living Cells
ACS Sens., 2017, 2 (12), pp 1847–1853
DOI: 10.1021/acssensors.7b00710

Fluorescent Binary Ensemble Based on Pyrene Derivative and Sodium Dodecyl Sulfate Assemblies as a Chemical Tongue for Discriminating Metal Ions and Brand Water
ACS Sens., 2017, 2 (12), pp 1821–1830
DOI: 10.1021/acssensors.7b00634

Universal Multifunctional Nanoplatform Based on Target-Induced in Situ Promoting Au Seeds Growth to Quench Fluorescence of Upconversion Nanoparticles
ACS Sens., 2017, 2 (12), pp 1805–1813
DOI: 10.1021/acssensors.7b00616

On Chip Protein Pre-Concentration for Enhancing the Sensitivity of Porous Silicon Biosensors
Open access through ACS AuthorChoice
ACS Sens., 2017, 2 (12), pp 1767–1773
DOI: 10.1021/acssensors.7b00692

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Analytical Chemistry

ATP-Activatable Photosensitizer Enables Dual Fluorescence Imaging and Targeted Photodynamic Therapy of Tumor
Anal. Chem., 2017, 89 (24), pp 13610–13617
DOI: 10.1021/acs.analchem.7b04197

Fast and Selective Two-Stage Ratiometric Fluorescent Probes for Imaging of Glutathione in Living Cells
Anal. Chem., 2017, 89 (24), pp 13112–13119
DOI: 10.1021/acs.analchem.7b02311

Ratiometric Detection of Intracellular Lysine and pH with One-Pot Synthesized Dual Emissive Carbon Dots
Anal. Chem., 2017, 89 (24), pp 13626–13633
DOI: 10.1021/acs.analchem.7b04211

Dual-Signal Readout Nanospheres for Rapid Point-of-Care Detection of Ebola Virus Glycoprotein
Anal. Chem., 2017, 89 (24), pp 13105–13111
DOI: 10.1021/acs.analchem.7b02222

Optical Nanoantenna for Single Molecule-Based Detection of Zika Virus Nucleic Acids without Molecular Multiplication
Open access through Editors’ Choice
Anal. Chem., 2017, 89 (23), pp 13000–13007
DOI: 10.1021/acs.analchem.7b04082

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Chemical Research in Toxicology

Molecular Signatures Associated with Treatment of Triple-Negative MDA-MB231 Breast Cancer Cells with Histone Deacetylase Inhibitors JAHA and SAHA
Open access through Editors’ Choice
Chem. Res. Toxicol., 2017, 30 (12), pp 2187–2196
DOI: 10.1021/acs.chemrestox.7b00269

Spotlight
Chem. Res. Toxicol., 2017, 30 (12), pp 2095–2096
DOI: 10.1021/acs.chemrestox.7b00316

Nicotine Alters the Gut Microbiome and Metabolites of Gut–Brain Interactions in a Sex-Specific Manner
Chem. Res. Toxicol., 2017, 30 (12), pp 2110–2119
DOI: 10.1021/acs.chemrestox.7b00162

Refinement of a Methodology for Untargeted Detection of Serum Albumin Adducts in Human Populations
Open access through ACS AuthorChoice
Chem. Res. Toxicol., 2017, 30 (12), pp 2120–2129
DOI: 10.1021/acs.chemrestox.7b00186

A Rapid Throughput Method To Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts
Chem. Res. Toxicol., 2017, 30 (12), pp 2130–2139
DOI: 10.1021/acs.chemrestox.7b00218

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Environmental Science & Technology

Stressor Exposures Determine Risk: So, Why Do Fellow Scientists Continue To Focus on Superficial Microplastics Risk?
Environ. Sci. Technol., 2017, 51 (23), pp 13515–13516
DOI: 10.1021/acs.est.7b05463

Remediation of Polluted Soil in China: Policy and Technology Bottlenecks
Open access through ACS AuthorChoice
Environ. Sci. Technol., 2017, 51 (24), pp 14027–14029
DOI: 10.1021/acs.est.7b05471

Lending an Eye to a Beleaguered Guardian of the Environment
Environ. Sci. Technol., 2017, 51 (24), pp 14025–14026
DOI: 10.1021/acs.est.7b06119

Land-Sparing Opportunities for Solar Energy Development in Agricultural Landscapes: A Case Study of the Great Central Valley, CA, United States
Environ. Sci. Technol., 2017, 51 (24), pp 14472–14482
DOI: 10.1021/acs.est.7b05110

Black Carbon (Biochar) In Water/Soil Environments: Molecular Structure, Sorption, Stability, and Potential Risk
Environ. Sci. Technol., 2017, 51 (23), pp 13517–13532
DOI: 10.1021/acs.est.7b02528

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Environmental Science & Technology Letters

Is the EPA Going To Protect the Environment?
Environ. Sci. Technol. Lett., 2017, 4 (12), pp 511–511
DOI: 10.1021/acs.estlett.7b00487

Biological Bromate Reduction Driven by Methane in a Membrane Biofilm Reactor
Environ. Sci. Technol. Lett., 2017, 4 (12), pp 562–566
DOI: 10.1021/acs.estlett.7b00488

Atmospheric Photooxidation Diminishes Light Absorption by Primary Brown Carbon Aerosol from Biomass Burning
Environ. Sci. Technol. Lett., 2017, 4 (12), pp 540–545
DOI: 10.1021/acs.estlett.7b00393

An Isotopic Dilution Approach for Quantifying Mercury Lability in Soils
Environ. Sci. Technol. Lett., 2017, 4 (12), pp 556–561
DOI: 10.1021/acs.estlett.7b00510

pH Dependence of the Imidazole-2-carboxaldehyde Hydration Equilibrium: Implications for Atmospheric Light Absorbance
Environ. Sci. Technol. Lett., 2017, 4 (12), pp 551–555
DOI: 10.1021/acs.estlett.7b00486

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Journal of Agricultural and Food Chemistry

Discovery of a New Fungicide Candidate through Lead Optimization of Pyrimidinamine Derivatives and Its Activity against Cucumber Downy Mildew
J. Agric. Food Chem., 2017, 65 (49), pp 10829–10835
DOI: 10.1021/acs.jafc.7b03898

Preparation of Lignin/Sodium Dodecyl Sulfate Composite Nanoparticles and Their Application in Pickering Emulsion Template-Based Microencapsulation
J. Agric. Food Chem., 2017, 65 (50), pp 11011–11019
DOI: 10.1021/acs.jafc.7b03784

Ellagitannins from Strawberries with Different Degrees of Polymerization Showed Different Metabolism through Gastrointestinal Tract of Rats
J. Agric. Food Chem., 2017, 65 (49), pp 10738–10748
DOI: 10.1021/acs.jafc.7b04120

Chemistry, Antimicrobial Mechanisms, and Antibiotic Activities of Cinnamaldehyde against Pathogenic Bacteria in Animal Feeds and Human Foods
J. Agric. Food Chem., 2017, 65 (48), pp 10406–10423
DOI: 10.1021/acs.jafc.7b04344

Bioactive Compounds of Edible Purple Laver Porphyra sp. (Nori)
J. Agric. Food Chem., 2017, 65 (49), pp 10685–10692
DOI: 10.1021/acs.jafc.7b04688
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Journal of Proteome Research

Progress and Future Direction of Chromosome-Centric Human Proteome Project
This article is part of the Chromosome-Centric Human Proteome Project 2017 special issue.
J. Proteome Res., 2017, 16 (12), pp 4253–4258
DOI: 10.1021/acs.jproteome.7b00734

Proteomics Standards Initiative: Fifteen Years of Progress and Future Work
This article is part of the Chromosome-Centric Human Proteome Project 2017 special issue.
J. Proteome Res., 2017, 16 (12), pp 4288–4298
DOI: 10.1021/acs.jproteome.7b00370

Quality Assessments of Long-Term Quantitative Proteomic Analysis of Breast Cancer Xenograft Tissues
This article is part of the Chromosome-Centric Human Proteome Project 2017 special issue.
J. Proteome Res., 2017, 16 (12), pp 4523–4530
DOI: 10.1021/acs.jproteome.7b00362

The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary Assays
This article is part of the Chromosome-Centric Human Proteome Project 2017 special issue.
J. Proteome Res., 2017, 16 (12), pp 4299–4310
DOI: 10.1021/acs.jproteome.7b00467

Synaptosomal Proteome of the Orbitofrontal Cortex from Schizophrenia Patients Using Quantitative Label-Free and iTRAQ-Based Shotgun Proteomics
This article is part of the Chromosome-Centric Human Proteome Project 2017 special issue.
J. Proteome Res., 2017, 16 (12), pp 4481–4494
DOI: 10.1021/acs.jproteome.7b00422

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