Biochemistry announces Methods/Protocols as a manuscript type, replacing From the Bench articles, capturing new and improved techniques that help to drive the field forward.
In 2017, Biochemistry launched the “From the Bench” manuscript type, featuring papers that showed biological chemistry is often driven by new tools, improvements to existing tools, and the clear communication of methods to enable use of these tools in new venues. At the time, this manuscript type was one of the first in an ACS journal dedicated to biological methods. In the years since, the ability to publish a focused methodological article has drawn in some exceptional papers.
Over the years, other ACS journals have similarly adopted manuscript types to outline procedures, techniques, methods, and protocols. To ensure that there is no confusion among readers as to the focus of our content, all ACS journals now use the same name for this category of article: “Methods/Protocols.”
At Biochemistry, the topical focus for Methods/Protocols remains the same as From the Bench:
- New methods that advance our combined capabilities
- Substantive improvements to existing methods
- Detailed protocols of high interest to the community
- Experimental procedures
- Computational methods
- Bioinformatic tools
Below, we explore some of the outstanding “From the Bench” papers that have appeared in Biochemistry, and we look forward to similar “Methods/Protocols” publications in the future.
If you have any questions about the suitability of your manuscript for the Methods/Protocols section, please email the journal at eic@biochem.acs.org.
Read more about article types in Biochemistry.
How to Submit
- Log in to the ACS Publishing Center.
- Select the "Journals" tab.
- Choose Biochemistry.
- Click "Submit."
- Select "Methods/Protocols."
If you have any questions about the suitability of your manuscript for the Methods/Protocols section, please email the journal at eic@biochem.acs.org.
Highlighted “From the Bench” Articles
Preparing Materials
Many biochemists know that the most difficult part of modern research is still preparing high-quality materials in a facile manner. These papers simplify those processes to make it easier to get to the fun stuff.
Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates
Urea-Assisted Reconstitution of Discoidal High-Density Lipoprotein
Data Processing
These papers focus on improving experimental readouts—developing more reliable assays, quantitative analyses, and in‑cell measurements—to help researchers distinguish real signal from artifact and make confident biological interpretations.
Common Pitfalls and Recommendations for Using a Turbidity Assay to Study Protein Phase Separation
MIPAR and ImageJ FIJI as Tools for Electron Microscopy Quantification of Amyloid Fibrils
Adaptation of RiPCA for the Live-Cell Detection of mRNA-Protein Interactions
Peptide-Dependent Growth in Yeast via Fine-Tuned Peptide/GPCR-Activated Essential Gene Expression
Computational Tools
These papers focus on methods that assemble, model, and contextualize complex biological data, so researchers can ask better questions before ever stepping into the lab.
Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design
Interpretation and Analysis
These papers focus on building accessible hardware and software tools that democratize experimental control and data analysis, lowering technical barriers so researchers can spend less time wrestling with equipment and code, and more time interpreting results.
pytc: Open-Source Python Software for Global Analyses of Isothermal Titration Calorimetry Data
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