We’ve compiled lists of the five most-read biological chemistry articles across the ACS journal portfolio in August 2019, including research, reviews, perspectives, and editorial pieces.

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in August 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

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Read more of August’s most-read articles.

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3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma
DOI: 10.1021/acs.jmedchem.9b00719

Synthetic Approaches to the New Drugs Approved During 2017
DOI: 10.1021/acs.jmedchem.9b00196

Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway
DOI: 10.1021/acs.jmedchem.9b00348

Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways
DOI: 10.1021/acs.jmedchem.9b00030

Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity
DOI: 10.1021/acs.jmedchem.9b00516

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