We’ve compiled lists of the five most-read biological chemistry articles across ACS journals in November 2017, including research, reviews, perspectives, and editorial pieces.
What were chemists reading in November of 2017? To find out, we’ve compiled lists of the five most-read chemistry articles that appeared in each analytical chemistry ACS Publications journal in November 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
Read More Great November 2017 Chemistry Research:
Analytical Chemistry | Applied Chemistry | Materials Science & Engineering | Multidisciplinary Chemistry | Organic/Inorganic Chemistry | Physical Chemistry
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ACS Biomaterials Science & Engineering
Integrated Multiscale Biomaterials Experiment and Modeling
This article is part of the Multiscale Biological Materials and Systems: Integration of Experiment, Modeling, and Theory special issue.
ACS Biomater. Sci. Eng., 2017, 3 (11), pp 2628–2632
DOI: 10.1021/acsbiomaterials.7b00821
Effects of Inflammation on Multiscale Biomechanical Properties of Cartilaginous Cells and Tissues
Open access through ACS AuthorChoice
ACS Biomater. Sci. Eng., 2017, 3 (11), pp 2644–2656
DOI: 10.1021/acsbiomaterials.6b00671
3D Bioprinting: New Directions in Articular Cartilage Tissue Engineering
ACS Biomater. Sci. Eng., 2017, 3 (11), pp 2657–2668
DOI: 10.1021/acsbiomaterials.6b00587
Mechanically and Electrically Enhanced CNT–Collagen Hydrogels As Potential Scaffolds for Engineered Cardiac Constructs
ACS Biomater. Sci. Eng., 2017, 3 (11), pp 3017–3021
DOI: 10.1021/acsbiomaterials.6b00620
Orthopedic Interface Repair Strategies Based on Native Structural and Mechanical Features of the Multiscale Enthesis
ACS Biomater. Sci. Eng., 2017, 3 (11), pp 2633–2643
DOI: 10.1021/acsbiomaterials.6b00599
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ACS Catalysis
Photocatalytic Water Splitting: Quantitative Approaches toward Photocatalyst by Design
Open Access Through ACS AuthorChoice
ACS Catal., 2017, 7 (11), pp 8006–8022
DOI: 10.1021/acscatal.7b02662
Carbon-Based Electrocatalysts for Hydrogen and Oxygen Evolution Reactions
ACS Catal., 2017, 7 (11), pp 7855–7865
DOI: 10.1021/acscatal.7b02718
Visible-Light-Driven Synthesis of 4-Alkyl/Aryl-2-Aminothiazoles Promoted by In Situ Generated Copper Photocatalyst
ACS Catal., 2017, 7 (11), pp 7941–7945
DOI: 10.1021/acscatal.7b02818
ZIF-67-Derived Nanoreactors for Controlling Product Selectivity in CO2 Hydrogenation
ACS Catal., 2017, 7 (11), pp 7509–7519
DOI: 10.1021/acscatal.7b01827
Two-Dimensional Mesoporous Carbon Doped with Fe–N Active Sites for Efficient Oxygen Reduction
ACS Catal., 2017, 7 (11), pp 7638–7646
DOI: 10.1021/acscatal.7b02101
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ACS Chemical Biology
Introducing Our Authors
ACS Chem. Biol., 2017, 12 (11), pp 2697–2698
DOI: 10.1021/acschembio.7b00955
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches
ACS Chem. Biol., 2017, 12 (11), pp 2906–2914
DOI: 10.1021/acschembio.7b00537
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
ACS Chem. Biol., 2017, 12 (11), pp 2730–2736
DOI: 10.1021/acschembio.7b00708
Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid–Peptide Vaccine
ACS Chem. Biol., 2017, 12 (11), pp 2898–2905
DOI: 10.1021/acschembio.7b00845
Targeted Disruption of Myc–Max Oncoprotein Complex by a Small Molecule
ACS Chem. Biol., 2017, 12 (11), pp 2715–2719
DOI: 10.1021/acschembio.7b00799
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ACS Chemical Neuroscience
Feeling Rejected? ACS Chemical Neuroscience Can Help Get Your Science to the Neuroscience Community As Quickly As Possible
ACS Chem. Neurosci., 2017, 8 (11), pp 2348–2348
DOI: 10.1021/acschemneuro.7b00380
Caring about Power Analyses
ACS Chem. Neurosci., 2017, 8 (11), pp 2352–2354
DOI: 10.1021/acschemneuro.7b003412
Embarking on a 5 Year Journey to Highlight Genetic and Rare Diseases of the Central Nervous System
ACS Chem. Neurosci., 2017, 8 (11), pp 2349–2349
DOI: 10.1021/acschemneuro.7b00401
The Medicinal Chemistry of Natural and Semisynthetic Compounds against Parkinson’s and Huntington’s Diseases
ACS Chem. Neurosci., 2017, 8 (11), pp 2356–2368
DOI: 10.1021/acschemneuro.7b00283
Future Priorities in Tackling Infections Due to Brain-Eating Amoebae
ACS Chem. Neurosci., 2017, 8 (11), pp 2355–2355
DOI: 10.1021/acschemneuro.7b00343
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ACS Infectious Diseases
Rigid Oxazole Acinetobactin Analog Blocks Siderophore Cycling in Acinetobacter baumannii
ACS Infect. Dis., 2017, 3 (11), pp 802–806
DOI: 10.1021/acsinfecdis.7b00146
Small-Molecule Potentiators for Conventional Antibiotics against Staphylococcus aureus
ACS Infect. Dis., 2017, 3 (11), pp 780–796
DOI: 10.1021/acsinfecdis.7b00084
Daptomycin Pore Formation Is Restricted by Lipid Acyl Chain Composition
ACS Infect. Dis., 2017, 3 (11), pp 797–801
DOI: 10.1021/acsinfecdis.7b00138
Reversibility of Covalent, Broad-Spectrum Serine β-Lactamase Inhibition by the Diazabicyclooctenone ETX2514
ACS Infect. Dis., 2017, 3 (11), pp 833–844
DOI: 10.1021/acsinfecdis.7b00113
Pyrazinoic Acid Inhibits Mycobacterial Coenzyme A Biosynthesis by Binding to Aspartate Decarboxylase PanD
Open access through ACS AuthorChoice
ACS Infect. Dis., 2017, 3 (11), pp 807–819
DOI: 10.1021/acsinfecdis.7b00079
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ACS Medicinal Chemistry Letters
Selective Estrogen Receptor Degraders (SERDs): A Promising Treatment to Overcome Resistance to Endocrine Therapy in ERα-Positive Breast Cancer
ACS Med. Chem. Lett., 2017, 8 (11), pp 1129–1131
DOI: 10.1021/acsmedchemlett.7b00424
Selective Inhibitors of Phosphodiesterase 4B (PDE-4B) May Provide a Better Treatment for CNS, Metabolic, Autoimmune, and Inflammatory Diseases
ACS Med. Chem. Lett., 2017, 8 (11), pp 1132–1133
DOI: 10.1021/acsmedchemlett.7b00425
Lysine-Specific Demethylase 1 (LSD1) Inhibitors as Potential Treatment for Different Types of Cancers
ACS Med. Chem. Lett., 2017, 8 (11), pp 1134–1135
DOI: 10.1021/acsmedchemlett.7b00426
Discovery of Indolinone-Based Multikinase Inhibitors as Potential Therapeutics for Idiopathic Pulmonary Fibrosis
ACS Med. Chem. Lett., 2017, 8 (11), pp 1142–1147
DOI: 10.1021/acsmedchemlett.7b00164
Benzoxaboroles as Efficient Inhibitors of the β-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study
ACS Med. Chem. Lett., 2017, 8 (11), pp 1194–1198
DOI: 10.1021/acsmedchemlett.7b00369
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ACS Synthetic Biology
Dynamic Blue Light-Inducible T7 RNA Polymerases (Opto-T7RNAPs) for Precise Spatiotemporal Gene Expression Control
ACS Synth. Biol., 2017, 6 (11), pp 2157–2167
DOI: 10.1021/acssynbio.7b00169
Controlling Bdellovibrio bacteriovorus Gene Expression and Predation Using Synthetic Riboswitches
Open access through ACS AuthorChoice
ACS Synth. Biol., 2017, 6 (11), pp 2035–2041
DOI: 10.1021/acssynbio.7b00171
Bacterial Microcolonies in Gel Beads for High-Throughput Screening of Libraries in Synthetic Biology
ACS Synth. Biol., 2017, 6 (11), pp 1988–1995
DOI: 10.1021/acssynbio.7b00111
The Timing of Transcriptional Regulation in Synthetic Gene Circuits
ACS Synth. Biol., 2017, 6 (11), pp 1996–2002
DOI: 10.1021/acssynbio.7b00118
An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis
ACS Synth. Biol., 2017, 6 (11), pp 2003–2013
DOI: 10.1021/acssynbio.7b00147
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Biochemistry
Defining Functional Structured RNA inside Living Cells
Biochemistry, 2017, 56 (44), pp 5847–5848
DOI: 10.1021/acs.biochem.7b00816
Molecules That Can Rewire the Taste System
Biochemistry, 2017, 56 (46), pp 6075–6076
DOI: 10.1021/acs.biochem.7b01061
Biological Roles of Protein Kinetic Stability
Biochemistry, 2017, 56 (47), pp 6179–6186
DOI: 10.1021/acs.biochem.7b00942
A Noncanonical Role for Yersiniabactin in Bacterial Copper Acquisition
Biochemistry, 2017, 56 (46), pp 6073–6074
DOI: 10.1021/acs.biochem.7b01003
Biosynthesis of an Opine Metallophore by Pseudomonas aeruginosa
Biochemistry, 2017, 56 (45), pp 5967–5971
DOI: 10.1021/acs.biochem.7b00804
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Bioconjugate Chemistry
Activated Microglia Targeting Dendrimer–Minocycline Conjugate as Therapeutics for Neuroinflammation
Bioconjugate Chem., 2017, 28 (11), pp 2874–2886
DOI: 10.1021/acs.bioconjchem.7b00569
Enzymatic Installation of Functional Molecules on Amyloid-Based Polymers
Bioconjugate Chem., 2017, 28 (11), pp 2687–2691
DOI: 10.1021/acs.bioconjchem.7b00479
Facile Formation of Gold-Nanoparticle-Loaded γ-Polyglutamic Acid Nanogels for Tumor Computed Tomography Imaging
Bioconjugate Chem., 2017, 28 (11), pp 2692–2697
DOI: 10.1021/acs.bioconjchem.7b00571
Improved Photoinduced Fluorogenic Alkene–Tetrazole Reaction for Protein Labeling
Bioconjugate Chem., 2017, 28 (11), pp 2859–2864
DOI: 10.1021/acs.bioconjchem.7b00562
Metal–Organic Frameworks@Polymer Composites Containing Cyanines for Near-Infrared Fluorescence Imaging and Photothermal Tumor Therapy
Bioconjugate Chem., 2017, 28 (11), pp 2784–2793
DOI: 10.1021/acs.bioconjchem.7b00508
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Biomacromolecules
Amphiphilic Peptide-Based Supramolecular, Noncytotoxic, Stimuli-Responsive Hydrogels with Antibacterial Activity
Biomacromolecules, 2017, 18 (11), pp 3621–3629
DOI: 10.1021/acs.biomac.7b01006
Organized Peptidic Nanostructures as Functional Materials
Biomacromolecules, 2017, 18 (11), pp 3469–3470
DOI: 10.1021/acs.biomac.7b01437
Supramolecular Copolymerization of Short Peptides and Polyoxometalates: toward the Fabrication of Underwater Adhesives
Biomacromolecules, 2017, 18 (11), pp 3524–3530
DOI: 10.1021/acs.biomac.7b00817
Antimicrobial Chitosan and Chitosan Derivatives: A Review of the Structure–Activity Relationship
Biomacromolecules, 2017, 18 (11), pp 3846–3868
DOI: 10.1021/acs.biomac.7b01058
Hydrogelation of a Naphthalene Diimide Appended Peptide Amphiphile and Its Application in Cell Imaging and Intracellular pH Sensing
Open access through ACS AuthorChoice
Biomacromolecules, 2017, 18 (11), pp 3630–3641
DOI: 10.1021/acs.biomac.7b01048
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Journal of Agricultural and Food Chemistry
Effectiveness of Commercial and Homemade Washing Agents in Removing Pesticide Residues on and in Apples
J. Agric. Food Chem., 2017, 65 (44), pp 9744–9752
DOI: 10.1021/acs.jafc.7b03118
An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice
Open access through ACS Editors’ Choice
J. Agric. Food Chem., 2017, 65 (43), pp 9435–9442
DOI: 10.1021/acs.jafc.7b02979
Identification of Lipid Biomarkers To Discriminate between the Different Production Systems for Asiago PDO Cheese
Open Access Through ACS AuthorChoice
J. Agric. Food Chem., 2017, 65 (45), pp 9887–9892
DOI: 10.1021/acs.jafc.7b03629
Do We No Longer Need To Worry about Dietary Cholesterol?
J. Agric. Food Chem., 2017, 65 (46), pp 9931–9933
DOI: 10.1021/acs.jafc.7b04829
Benzoyl Peroxide Detection in Real Samples and Zebrafish Imaging by a Designed Near-Infrared Fluorescent Probe
J. Agric. Food Chem., 2017, 65 (43), pp 9553–9558
DOI: 10.1021/acs.jafc.7b03598
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Journal of Chemical Theory and Computation
Cheap and Near Exact CASSCF with Large Active Spaces
Open access through ACS Editors’ Choice
J. Chem. Theory Comput., 2017, 13 (11), pp 5468–5478
DOI: 10.1021/acs.jctc.7b00900
Unifying Exchange Sensitivity in Transition-Metal Spin-State Ordering and Catalysis through Bond Valence Metrics
J. Chem. Theory Comput., 2017, 13 (11), pp 5443–5457
DOI: 10.1021/acs.jctc.7b00848
Automated Transition State Search and Its Application to Diverse Types of Organic Reactions
J. Chem. Theory Comput., 2017, 13 (11), pp 5780–5797
DOI: 10.1021/acs.jctc.7b00764
Prediction Errors of Molecular Machine Learning Models Lower than Hybrid DFT Error
J. Chem. Theory Comput., 2017, 13 (11), pp 5255–5264
DOI: 10.1021/acs.jctc.7b00577
Evaluation of the Factors Impacting the Accuracy of 13C NMR Chemical Shift Predictions using Density Functional Theory—The Advantage of Long-Range Corrected Functionals
Open access through ACS AuthorChoice
J. Chem. Theory Comput., 2017, 13 (11), pp 5798–5819
DOI: 10.1021/acs.jctc.7b00772
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Journal of Medicinal Chemistry
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)
J. Med. Chem., 2017, 60 (22), pp 9184–9204
DOI: 10.1021/acs.jmedchem.7b00941
Structure-Based Design and Discovery of New M2 Receptor Agonists
J. Med. Chem., 2017, 60 (22), pp 9239–9250
DOI: 10.1021/acs.jmedchem.7b01113
Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent μ-Opioid Receptor Agonists
Open Access Through ACS AuthorChoice
J. Med. Chem., 2017, 60 (22), pp 9407–9412
DOI: 10.1021/acs.jmedchem.7b01363
Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity
J. Med. Chem., 2017, 60 (22), pp 9393–9399
DOI: 10.1021/acs.jmedchem.7b00716
Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design
Open Access Through ACS Editors’ Choice
J. Med. Chem., 2017, 60 (21), pp 8708–8715
DOI: 10.1021/acs.jmedchem.7b00845
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Journal of Natural Products
Houttuynoid M, an Anti-HSV Active Houttuynoid from Houttuynia cordata Featuring a Bis-houttuynin Chain Tethered to a Flavonoid Core
J. Nat. Prod., 2017, 80 (11), pp 3010–3013
DOI: 10.1021/acs.jnatprod.7b00620
Natural Products with Heteroatom-Rich Ring Systems
J. Nat. Prod., 2017, 80 (11), pp 3060–3079
DOI: 10.1021/acs.jnatprod.7b00575
Deinococcucins A–D, Aminoglycolipids from Deinococcus sp., a Gut Bacterium of the Carpenter Ant Camponotus japonicusa
J. Nat. Prod., 2017, 80 (11), pp 2910–2916
DOI: 10.1021/acs.jnatprod.7b00426
Cytotoxic Cardiac Glycoside Constituents of Vallaris glabra Leaves
J. Nat. Prod., 2017, 80 (11), pp 2987–2996
DOI: 10.1021/acs.jnatprod.7b00554
Bacilotetrins A and B, Anti-Staphylococcal Cyclic-Lipotetrapeptides from a Marine-
J. Nat. Prod., 2017, 80 (11), pp 2889–2892
DOI: 10.1021/acs.jnatprod.7b00356
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The Journal of Physical Chemistry B
Not Physical Chemistry (in the Eyes of the Journal of Physical Chemistry)
J. Phys. Chem. B, 2017, 121 (44), pp 10199–10199
DOI: 10.1021/acs.jpcb.7b09460
Virtual Issue in Honor of the 150th Birthday of Marie Curie: Highlighting Female Physical Chemists
J. Phys. Chem. B, 2017, 121 (43), pp 9983–9985
DOI: 10.1021/acs.jpcb.7b09653
The Hydrophobic Effect and the Role of Cosolvents
Open Access Through ACS Editors’ Choice
J. Phys. Chem. B, 2017, 121 (43), pp 9986–9998
DOI: 10.1021/acs.jpcb.7b06453
Free-Energy Surface Prediction by Flying Gaussian Method: Multisystem Representation
J. Phys. Chem. B, 2017, 121 (46), pp 10479–10483
DOI: 10.1021/acs.jpcb.7b09337
Ab Initio Molecular Dynamics Simulation of the Phosphate Ion in Water: Insights into Solvation Shell Structure, Dynamics, and Kosmotropic Activity
J. Phys. Chem. B, 2017, 121 (46), pp 10519–10529
DOI: 10.1021/acs.jpcb.7b06091
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The Journal of Physical Chemistry Letters
Size-Dependent Level Alignment between Rutile and Anatase TiO2 Nanoparticles: Implications for Photocatalysis
J. Phys. Chem. Lett., 2017, 8 (22), pp 5593–5598
DOI: 10.1021/acs.jpclett.7b02474
Transfer of Inorganic-Capped Nanocrystals into Aqueous Media
J. Phys. Chem. Lett., 2017, 8 (22), pp 5573–5578
DOI: 10.1021/acs.jpclett.7b02319
Probing the OH Stretch in Different Local Environments in Liquid Water
J. Phys. Chem. Lett., 2017, 8 (22), pp 5487–5491
DOI: 10.1021/acs.jpclett.7b02060
Direct Mapping of Band Positions in Doped and Undoped Hematite during Photoelectrochemical Water SplittingJ. Phys. Chem. Lett., 2017, 8 (22), pp 5579–5586
DOI: 10.1021/acs.jpclett.7b02548
Biological Molecules-Governed Plasmonic Nanoparticle Dimers with Tailored Optical Behaviors
J. Phys. Chem. Lett., 2017, 8 (22), pp 5633–5642
DOI: 10.1021/acs.jpclett.7b01781
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Journal of Proteome Research
Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range
J. Proteome Res., 2017, 16 (11), pp 4060–4072
DOI: 10.1021/acs.jproteome.7b00433
Experimental Design in Clinical ‘Omics Biomarker Discovery
Open access through ACS AuthorChoice
J. Proteome Res., 2017, 16 (11), pp 3954–3960
DOI: 10.1021/acs.jproteome.7b00418
Innovations in Publishing: Prepublication of Manuscripts on Preprint Servers
J. Proteome Res., 2017, 16 (11), pp 3953–3953
DOI: 10.1021/acs.jproteome.7b00674
Sensitive and Accurate Quantitation of Phosphopeptides Using TMT Isobaric Labeling Technique
J. Proteome Res., 2017, 16 (11), pp 4244–4252
DOI: 10.1021/acs.jproteome.7b00610
Unrestricted Mass Spectrometric Data Analysis for Identification, Localization, and Quantification of Oxidative Protein Modifications
J. Proteome Res., 2017, 16 (11), pp 3978–3988
DOI: 10.1021/acs.jproteome.7b00330
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Molecular Pharmaceutics
Multidrug, Anti-HIV Amorphous Solid Dispersions: Nature and Mechanisms of Impacts of Drugs on Each Other’s Solution Concentrations
Open access through ACS AuthorChoice
Mol. Pharmaceutics, 2017, 14 (11), pp 3617–3627
DOI: 10.1021/acs.molpharmaceut.7b00203
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy
Mol. Pharmaceutics, 2017, 14 (11), pp 3644–3659
DOI: 10.1021/acs.molpharmaceut.7b00404
Reduction-sensitive Paclitaxel Prodrug Self-assembled Nanoparticles with Tetrandrine Effectively Promote Synergistic Therapy Against Drug-sensitive and Multidrug-resistant Breast Cancer
Mol. Pharmaceutics, 2017, 14 (11), pp 3628–3635
DOI: 10.1021/acs.molpharmaceut.7b00381
Lymphoma Immunochemotherapy: Targeted Delivery of Doxorubicin via a Dual Functional Nanocarrier
Mol. Pharmaceutics, 2017, 14 (11), pp 3888–3895
DOI: 10.1021/acs.molpharmaceut.7b00606
Receptor-Mediated Attachment and Uptake of Hyaluronan Conjugates by Breast Cancer Cells
Mol. Pharmaceutics, 2017, 14 (11), pp 3968–3977
DOI: 10.1021/acs.molpharmaceut.7b00636
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