This Special Issue will focus on the dynamic topic of biased signaling, seeking contributions that deconstruct its structural details, make new functional connections, and expand to new biology. Submit by December 31, 2024.

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Living organisms must sense and respond to a multitude of inputs using a finite number of biological effectors. The discovery that the same proteins can yield different outputs in response to distinct ligands led to a paradigm shift in our understanding of cellular signaling and opened a variety of questions regarding the biochemical basis for these different connections.

A new Special Issue from Biochemistry will focus on this dynamic topic, including contributions that deconstruct the structural details of biased signaling, make new functional connections, and expand to new biology.

Relevant topics include:

  • Cell surface receptor structure/function studies
  • New insights into signaling pathways
  • New tools/sensors to differentiate signaling pathways
  • Biological consequences of biased signaling
  • New tools/techniques to investigate protein structure and dynamics

Organizing Editor

Prof. Bryan Roth, Executive Editor, Biochemistry
University of North Carolina at Chapel Hill, United States

How to Submit

  • Log in to the ACS Pubishing Center.
  • Select the “Journals” tab
  • Search for Biochemistry.
  • Click "Submit."
  • Select your manuscript type, and, under “Special Issue Selection,” choose “Biased Signaling.”

Please see Biochemistry’s Author Guidelines for more information on submission requirements. The deadline for submissions is December 31, 2024.

Open Access: There are diverse open access options for publications in American Chemical Society journals. Please visit our Open Science Resource Center for more information.

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