Call for Papers: Lipids and Lipidation

Lipids support cellular physiology at the structural and functional levels across all kingdoms of life. These hydrophobic metabolites act both as free molecules, often within cellular membranes, and as covalent conjugates to other macromolecules in a process termed lipidation. With this special issue, we aim to bring together researchers from across these disciplines to share their knowledge and their latest advances.

We are pleased to announce that ACS Chemical Biology and Biochemistry will publish a Special Issue titled “Lipids and Lipidation.” This Special Issue aims to highlight the latest advancements and perspectives in this field. It will focus on how chemical approaches are uniquely positioned to elucidate fundamental cellular mechanisms and target factors involved in lipidation, lipid metabolism, and lipid signaling that underlie disease, and it will feature biochemical studies that clarify the kinetics of these pathways.

In the Lipids and Lipidation Special Issue, we welcome papers focused on the chemical biology and biochemistry of lipids and lipidation, including but not necessarily limited to the following topics:

• Imaging probes for visualization of lipids and lipidation
• Chemoproteomics approaches for lipidation and non-covalent lipid–protein interactions
• Regulation of writers, erasers, and readers of lipidation
• Molecular mechanisms underlying lipid metabolism, transport, and signaling
• Therapeutic targeting of machinery involved in lipid metabolism and lipidation
• Biochemical, kinetic, or structural studies of how lipids and lipidation regulate biomolecule function

Organizing Editors

Bryan Dickinson, Guest Editor
University of Chicago, United States

Jeremy Baskin, Guest Editor
Cornell University, United States

Submission Information

We welcome submissions for this VSI through May 31, 2026. For more information on submission requirements, please visit each journal’s Author Guidelines page:

• ACS Chemical Biology
• Biochemistry

Accepted manuscripts for consideration in this Special Issue will include any research article types as well as perspectives and reviews. Papers accepted for publication will be available ASAP (as soon as publishable) online. After all submissions have been published, they will then be compiled online on a dedicated landing page to form the Special Issue. Manuscripts submitted for consideration will undergo the full rigorous peer review process expected from ACS journals.

Open Access: There are diverse open access options for publications in American Chemical Society journals. Please visit our Open Science Resource Center for more information.

How to Submit

• Log in to the ACS Publishing Center.
• Select the “Journals” tab.
• Search for ACS Chemical Biology or Biochemistry.
• Click "Submit."
• Select your manuscript type, and, under "Special Issue Selection," choose “Lipids and Lipidation."

If you have any general questions regarding submission to this Special Issue, please contact managing.editor@chembio.acs.org or managing.editor@biochem.acs.org.