This Special Issue, will highlight wearable, implantable, and minimally invasive biointerface systems that connect patient-specific biological signals with digital medical technologies. Submit your manuscript by October 31, 2026.
Wearable and implantable technologies are transforming how biological signals are captured, interpreted, and translated into personalized medical insight. By integrating biointerface engineering with biosensing, wireless operation, and data-driven analysis, these systems are enabling continuous monitoring, adaptive intervention, and patient-specific healthcare.
Digital Medical Engineering seeks contributions on integrated platforms that acquire physiological, biochemical, biomechanical, electrophysiological, neural, or molecular information from the body and translate these signals into actionable outputs for precision diagnostics, longitudinal monitoring, closed-loop therapy, or personalized intervention.
Rather than focusing on wearable or implantable devices as standalone hardware, this Special Issue emphasizes systems in which biointerface design, signal acquisition, digital interpretation, and medical relevance are closely linked. Submissions should clearly articulate how the proposed technology advances precision health through patient-specific measurement, data-driven insight, adaptive control, or clinically meaningful validation.
Topics of Interest
Submissions may include, but are not limited to, the following areas:
Wearable and Skin-Interfaced Biointerfaces
- Flexible, stretchable, soft, epidermal, textile-based, and conformal systems for continuous or longitudinal health monitoring
- Wearable biosensors for physiological, biochemical, electrophysiological, biomechanical, metabolic, or environmental signal acquisition
- Multimodal wearable platforms that integrate sensing, communication, and data interpretation for personalized health assessment
Implantable and Minimally Invasive Biointerfaces
- Implantable and minimally invasive sensors, stimulators, actuators, and closed-loop therapeutic systems
- Neural, cardiac, metabolic, musculoskeletal, gastrointestinal, immune, and organ-specific biointerfaces
- Smart implants for long-term monitoring, neuromodulation, drug delivery, and adaptive therapy
Materials, Device Architectures, and Wireless Systems
- Soft, biocompatible, bioadhesive, and conductive materials for wearable and implantable digital biointerfaces
- Biointerface designs for long-term stability, tissue integration, immune compatibility, and mechanical matching
- Wireless communication, power transfer, energy harvesting, low-power electronics, packaging, and system integration
Precision Health, Closed-Loop Therapy, and Clinical Translation
- Biointerface-enabled digital biomarkers and patient-specific analytics
- AI- and data-driven interpretation of wearable or implantable biointerface data
- Closed-loop systems, preclinical or human validation, and clinically oriented engineering studies
Organizing Editors
Prof. Jae-Woong Jeong, Associate Editor, Digital Medical Engineering
KAIST, Republic of Korea
Prof. Zhuo Li, Guest Editor
Fudan University, China
Prof. Hedan Bai, Guest Editor
ETH Zurich, Switzerland
Prof. Yuanwen Jiang, Guest Editor
University of Pennsylvania, USA
Submission Information
Manuscripts accepted for inclusion in this Special Issue will be highlighted as a significant contribution to this expanding field. If accepted, publications will go online as soon as possible with a DOI, and will be published in one of the next available issues. Publications on this topic will be assembled into a Special Issue and widely promoted.
Submissions are welcome through Oct 31, 2026. All articles will be peer reviewed prior to acceptance to ensure they fit the scope of the Special Issue and meet the scientific publishing standards of Digital Medical Engineering. The peer review process for all papers will be managed by the journal editors to ensure rigor is maintained.
Digital Medical Engineering is an open access journal. The Article Publishing Charges are waived for submissions before December 31, 2028.
How to Submit
- Log in to the ACS Publishing Center.
- Select your manuscript type and upload your manuscript and related files.
- Review the title and abstract fields to ensure any pre-populated information has uploaded correctly.
- Under "Special Issue Selection," select Wearable and Implantable Biointerfaces for Digital Precision Health.
- Confirm all other information has uploaded correctly.
- Submit your article.
Please see our Author Guidelines for more information on submission requirements. The deadline for submissions is Oct 31, 2026.
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