Here, we discover the most-read chemistry articles across ACS journals in April 2021, including research, reviews, perspectives, and editorial pieces.

Celebrating Prof. Renato Zenobi at Ions and Photons in Analytical Science 2021

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that were published in each ACS Publications journal during April 2021, including papers, reviews, perspectives, and editorial pieces. These lists were not chosen by the journals’ editors and should not be taken as a “best of” list, but as another perspective on what newly published research attracted the most attention in a particular month.

Click on your favorite journal below to see their most-read articles that were published in April 2021.

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Browse Other Monthly Most-Read Article Lists From 2021

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Modulating Androgen Receptor in the Therapeutic Intervention for Prostate Cancer and Kennedy’s Disease
DOI: 10.1021/acsmedchemlett.1c00177

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase as a Therapeutic Strategy for Cancer
DOI: 10.1021/acsmedchemlett.1c00178

Novel Substituted Exomethylene-oxindoles as HPK1 Inhibitors
DOI: 10.1021/acsmedchemlett.1c00172

Novel Pyrazolo[3,4-b]pyrazines as SHP2 Inhibitors for Treating Cancer
DOI: 10.1021/acsmedchemlett.1c00173

Medicinal Chemistry in Portugal and Spain: A Strong Iberian Alliance — Call for Papers
DOI: 10.1021/acsmedchemlett.1c00143

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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.1c00095

Quest for a Cure: Potential Small-Molecule Treatments for COVID-19, Part 2
DOI: 10.1021/acs.oprd.1c00100

From Bench to Plant: An Opportunity for Transition Metal Paired Electrocatalysis
DOI: 10.1021/acs.oprd.1c00046

Development of Two Synthetic Approaches to an APJ Receptor Agonist Containing a Tetra-ortho-Substituted Biaryl Pyridone
DOI: 10.1021/acs.oprd.1c00046

Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine
DOI: 10.1021/acs.oprd.1c00088

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Isotope Effects and the Mechanism of Photoredox-Promoted [2 + 2] Cycloadditions of Enones
DOI: 10.1021/acs.joc.1c00099

Role of Acetate Anions in the Catalytic Formation of Isocyanurates from Aromatic Isocyanates
DOI: 10.1021/acs.joc.1c00119

Polarized Helical Coumarins: [1,5] Sigmatropic Rearrangement and Excited-State Intramolecular Proton Transfer
DOI: 10.1021/acs.joc.0c02978

Photoredox Propargylation of Aldehydes Catalytic in Titanium
DOI: 10.1021/acs.joc.1c00521

I2-Catalyzed Three-Component Consecutive Reaction for the Synthesis of 3-Aroylimidazo[1,2-a]-N-Heterocycles
DOI: 10.1021/acs.joc.1c00023

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