Stay up to date with a selection of recently published articles from ACS journals that were among the most read in November 2025.
The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during November 2025, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”
Browse Highly Read ACS Journal Articles in November 2025
What Do Oral Drugs Really Look Like? Dose Regimen, Pharmacokinetics, and Safety of Recently Approved Small-Molecule Oral Drugs
Dean G. Brown*
DOI: 10.1021/acs.jmedchem.5c02863
DOI: 10.1021/acs.jmedchem.5c02863
Enantioselective Synthesis of (+)-Auriculatol A
Jordan K. Thompson, Kala C. Youngblood, Yun Hao Shawn Teh, Conner M. Farley, Zhehao Zhang, Scott C. Virgil, and Sarah E. Reisman*
DOI: 10.1021/jacs.5c17269
DOI: 10.1021/jacs.5c17269
A Unified Synthetic Approach to 2-Alkyl Azetidines, Oxetanes, Thietanes and Cyclobutanes from Unactivated Alkenes
Louis Buck, Maria Pelosi, Subhasis Paul, Emilie Wheatley, Adam Richardson, Soumen Ghosh, Francesca Sardelli, and Mattia Silvi*
DOI: 10.1021/jacs.5c11758
DOI: 10.1021/jacs.5c11758
Spontaneous Transport Mechanics of Water Droplets under a Synergistic Action of Designed Pattern and Non-Wetting Gradient
Weilan Liu, Yang Lu, Yizhou Shen*, Haifeng Chen, Yaru Ni*, and Yangjiangshan Xu
DOI: 10.1021/acsomega.3c01536
DOI: 10.1021/acsomega.3c01536
Short, Enantioselective Total Synthesis of (+)-Ineleganolide
Kuan Yu*, Aikaterini Gorou, Danny Huang, and Thomas J. Maimone*
DOI: 10.1021/jacs.5c17640
DOI: 10.1021/jacs.5c17640
Revealing Solvent-Assisted Li+ Transport in the Solid Electrolyte Interphase operando
Jacob Florian, Hao Lyu, Il Rok Choi, Luca Mondonico, Steven Lam, Yepin Zhao, Min-Jae Kim, Andrew Westover, Yi Cui, Robert L. Sacci*, and Zhenan Bao*
DOI: 10.1021/jacs.5c14284
DOI: 10.1021/jacs.5c14284
Temperature Cycling Induced Deracemization of p-Synephrine in the Presence of Degradation
Po Sang Lo, Madiha Nisar, and Richard Lakerveld*
DOI: 10.1021/acsomega.4c06807
DOI: 10.1021/acsomega.4c06807
DRTtools: Freely Accessible Distribution of Relaxation Times Analysis for Electrochemical Impedance Spectroscopy
Zilong Wang, Yuhao Wang*, Baptiste Py, Adeleke Maradesa, Jiapeng Liu, Ting Hei Wan, Mattia Saccoccio, and Francesco Ciucci*
DOI: 10.1021/acselectrochem.5c00334
DOI: 10.1021/acselectrochem.5c00334
General Light-Induced Pd-Catalyzed Allylic C–H Alkylation of Internal Alkenes: Direct Access to Tertiary and Quaternary Carbon Centers
Subham Pradhan, Gaurav Prakash, and Vladimir Gevorgyan*
DOI: 10.1021/jacs.5c15245
DOI: 10.1021/jacs.5c15245
Development, Application, and Mechanistic Interrogation of a Dual Ni Catalysis Approach to Photoredox-Based C(sp3)–C(sp3) Cross-Coupling
Erin M. Bucci, Melecio A. Perea, Remy F. Lalisse, Poulami Mukherjee, T. Judah Raab, Lakshmy Kannadi Valloli, Daniel S. Min, Matthew J. Bird*, Osvaldo Gutierrez*, and Abigail G. Doyle*
DOI: 10.1021/jacs.5c10906
DOI: 10.1021/jacs.5c10906
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.
