Stay up to date with a selection of recently published articles from ACS journals that were among the most read in June 2025.
The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during June 2025, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”
Browse Highly Read ACS Journal Articles in June 2025
Elevated Toxic Element Emissions from Popular Disposable E-Cigarettes: Sources, Life Cycle, and Health Risks
Mark R. Salazar, Lalima Saini, Tran B. Nguyen, Kent E. Pinkerton, Amy K. Madl, Austin M. Cole, and Brett A. Poulin*
DOI: 10.1021/acscentsci.5c00641
DOI: 10.1021/acscentsci.5c00641
Radical Strategy to the Boron-to-Copper Transmetalation Problem: N-Alkylation with Alkylboronic Esters
Ruocheng Sang* and Jason E. Gestwicki*
DOI: 10.1021/jacs.5c07856
DOI: 10.1021/jacs.5c07856
Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations
Jingjing Wu, Hui Wang, Huaquan Fang, Kevin C. Wang, Deborin Ghosh, Valerio Fasano, Adam Noble*, and Varinder K. Aggarwal*
DOI: 10.1021/jacs.5c03864
DOI: 10.1021/jacs.5c03864
Magnetic Stirring May Cause Irreproducible Results in Chemical Reactions
Vera A. Cherepanova, Evgeniy G. Gordeev, and Valentine P. Ananikov*
DOI: 10.1021/jacsau.5c00412
DOI: 10.1021/jacsau.5c00412
Enantioselective β-C(sp3)–H Nucleophilic Tosylation of Native Amides: A Synthetic Platform for Chiral Methyl Stereocenters
Yuxin Ouyang, D. Quang Phan, Nikita Chekshin, Yi-Hao Li, Jennifer X. Qiao, Martin D. Eastgate, and Jin-Quan Yu*
DOI: 10.1021/jacs.4c17267
DOI: 10.1021/jacs.4c17267
Iridium Polypyridyl Carboxylates as Excited-State PCET Catalysts for the Functionalization of Unactivated C–H Bonds
Diego A. Granados, Y. Emily Du, Shiloh J. Andersson, Avery Cirincione-Lynch, Kai Cui, Adam Reinhold, Philip D. Jeffrey, Gregory D. Scholes*, Sharon Hammes-Schiffer*, and Robert R. Knowles*
DOI: 10.1021/jacs.5c04000
DOI: 10.1021/jacs.5c04000
Target Engagement Assays in Early Drug Discovery
Sahra St John-Campbell* and Gurdip Bhalay
DOI: 10.1021/acs.jmedchem.4c03115
DOI: 10.1021/acs.jmedchem.4c03115
Cooperative Organosulfur/Photoredox Catalysis Enables Radical-Polar Crossover C(sp3)–N Coupling via Inner-Sphere Electron Shuttling
Youngeun Hong, Changkyu Park, Junseong Jang, Minseok Oh, Dongwook Kim, Seunghoon Lee*, and Seung Youn Hong*
DOI: 10.1021/jacs.5c00352
DOI: 10.1021/jacs.5c00352
MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration
Ranjan Kumar Acharyya, Liyue Huang, Angelo Aguilar*, Biao Hu, Longchuan Bai, Hoda Metwally, Donna McEachern, Wei Jiang, Yu Wang, Qiuxia Li, Bo Wen, Duxin Sun, and Shaomeng Wang*
DOI: 10.1021/acs.jmedchem.5c00809
DOI: 10.1021/acs.jmedchem.5c00809
Unlocking Chromium Decarboxylative Ligand-to-Metal Charge Transfer: Efficient and Redox-Neutral Allylation of Aldehydes Using Carboxylic Acids
Supeng Wu, Ziqi Jiao, Alex T. Sung, Abigail B. Faulhaber, Nathan D. Schley, and Alexander W. Schuppe*
DOI: 10.1021/jacs.5c04691
DOI: 10.1021/jacs.5c04691
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.
