There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five […]

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that were published in each ACS Publications journal during 2021, including papers, reviews, perspectives, and editorial pieces. These lists were not chosen by the journals’ editors and should not be taken as a “best of” list, but as another perspective on what newly published research attracted the most attention in a particular month.

Click on your favorite journal below to see their most-read articles that were published in January of 2022.

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Solid–Liquid Equilibria and Kinetics of the Solid Formation in Binary and Ternary Mixtures Containing (Formaldehyde + Water + Methanol)
DOI: 10.1021/acs.iecr.1c04275

Predicting Solvent Effects on Homogeneity and Kinetics of the Hydroaminomethylation: A Thermodynamic Approach Using PC-SAFT
DOI: 10.1021/acs.iecr.1c03891

Machine Learning-Based Operational Modeling of an Electrochemical Reactor: Handling Data Variability and Improving Empirical Models
DOI: 10.1021/acs.iecr.1c04176

Optimizing the Properties of Hybrids Based on Graphene Oxide for Carbon Dioxide Capture
Open Access
DOI: 10.1021/acs.iecr.1c02922

Application-Related Consideration of the Thermal Stability of [mTBDH][OAc] Compared to Amidine-Based Ionic Liquids in the Presence of Various Amounts of Water
Open Access
DOI: 10.1021/acs.iecr.1c04015

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Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers
This article is part of the Epigenetics 2022 special issue.
Open Access
DOI: 10.1021/acs.jmedchem.1c01900

Targeting the Non-Catalytic Functions: a New Paradigm for Kinase Drug Discovery?
DOI: 10.1021/acs.jmedchem.1c01978

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery
DOI: 10.1021/acs.jmedchem.1c01687

Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists
Open Access
DOI: 10.1021/acs.jmedchem.1c01636

Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects
DOI: 10.1021/acs.jmedchem.1c00672

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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.1c00482

Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir
Open Access
DOI: 10.1021/acs.oprd.1c00071

When Safety Data Sheets are a Safety Hazard
DOI: 10.1021/acs.oprd.1c00427

Multigram Synthesis of Tetrasubsituted Dihydrobenzofuran GSK973 Enabled by High-Throughput Experimentation and a Claisen Rearrangement in Flow
DOI: 10.1021/acs.oprd.1c00422

Convenient, Large-Scale Synthesis of (S)-TRIP Using Suzuki Cross-Coupling Conditions
DOI: 10.1021/acs.oprd.1c00386

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Making 2022 Picture Perfect
DOI: 10.1021/acs.organomet.2c00022

Insights into H2 Activation and Styrene Hydrogenation by Nickel–Borane and Nickel–Alane Bifunctional Catalysts
DOI: 10.1021/acs.organomet.1c00620

Synthesis and Structures of Tris(cyclononatetraenyl) Rare-Earth Complexes [Ln(C9H9)3] (Ln = Y, Gd, Tb, Dy, Ho, Er, Tm)
DOI: 10.1021/acs.organomet.1c00590

Role of Anion in Determining the Stereoselectivity of Mg-Ph-BOX-Catalyzed Diels–Alder Reactions: A Computational Study
Open Access
DOI: 10.1021/acs.organomet.1c00550

Alkyl Complexes of Iron(IV) Triphenylcorrole
DOI: 10.1021/acs.organomet.1c00635

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