Stay up to date with a selection of recently published articles from ACS journals that were among the most read in February 2025.

Artistic depiction of a protein structure amidst stylized cellular components, with a swirling background of vibrant colors, illustrating a biological or molecular scene.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during Februay 2025, showcasing influential and trending research across ACS journals.*

We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”

Most-Read ACS Journal Articles: February 2025
Journal of Medicinal Chemistry Cover

Identification of Structurally Novel KRASG12C Inhibitors through Covalent DNA-Encoded Library Screening

David Huang, Francesco Manoni, Zhen Sun, Rongfeng Liu, Jennifer R. Allen, Abhisek Banerjee, Victor J. Cee, Josephine Eshon, Michael J. Frohn, Matthew R. Kaller, Heejun Lee, Cui Li, Xun Li, Patricia Lopez, Vu Ma, Jose M. Medina, Christopher Mohr, Olga A. Mukhina, Alexander J. Pickrell, John Stellwagen, Wenting Wu, Wenhan Zhang, Kai Zhu, Upendra P. Dahal, Liaoyuan A. Hu, Monica Leavitt, Wencui Li, Yu Li, Yingli Ma, Karen Rex, Anne Y. Saiki, Paul Wang, Yaping Sun, Dongcheng Dai, Nuria A. Tamayo, and Brian A. Lanman*
DOI: 10.1021/acs.jmedchem.4c03071

*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.

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