This Special Issue will address the toxicological risks posed by emerging environmental pollutants and their mixtures. Submit your manuscript by October 15, 2026.
This Special Issue of Chemical Research in Toxicology will address the toxicological risks posed by emerging environmental pollutants, which are increasingly recognized as threats to human and animal health. The issue will highlight critical contaminant classes, including micro- and nanoplastics and plastic-associated chemicals, per- and polyfluoroalkyl substances (PFAS; both legacy compounds and alternatives), flame retardants (legacy and next-generation), pharmaceutics, personal care products, particle and chemical emissions from emerging and advanced manufacturing processes (e.g., battery production, 3D printing), as well as their mixtures.
We welcome contributions that explore mechanistic toxicology using in vitro, in vivo, and computational approaches. Emphasis will be placed on studies that leverage multi-omics (genomics, transcriptomics, proteomics, and metabolomics) high-content and high-throughput data to elucidate molecular and cellular pathways of toxicity, thereby enabling the development of predictive models for health risk assessment. Research involving the development and validation of reference materials to standardize toxicological evaluation of emerging contaminants is also encouraged.
Topics of interest include mechanistic insights into biological effects, such as modulation of molecular signal pathways, mixture effects, characterization of complex exposure scenarios, and innovative strategies to promote (open solution-oriented) strategies. Manuscripts employing advanced computational toxicology, artificial intelligence, and systems biology to integrate complex datasets and predict adverse outcomes are strongly encouraged.
By bringing together cutting-edge research across diverse emerging contaminant classes, this Special Issue aims to advance mechanistic understanding, refine predictive approaches, and inform future regulatory and public health strategies.
Organizing Editors
Prof. Karla Oyuky Juárez Moreno, Associate Editor, Chemical Research in Toxicology
Universidad Nacional Autónoma de México, Mexico
Prof. Jiayin Dai, Associate Editor, Chemical Research in Toxicology
Shanghai Jiao Tong University, China
Prof. Andi Alijagic, Guest Editor
Örebro University, Sweden
Prof. Rui Hou, Guest Editor
Guangdong University of Technology, China
Submission Information
We welcome submissions for this Special Issue through October 15, 2026. For more information on submission requirements, please visit the journal’s Author Guidelines page.
Accepted manuscripts for consideration in this Special Issue will include research articles, reviews, perspectives, and ToxWatch. Papers accepted for publication for this Special Issue will be available ASAP (as soon as publishable) online as soon as they are accepted. After all submissions have been published, they will then be compiled online on a dedicated landing page to form the Special Issue. Manuscripts submitted for consideration will undergo the full rigorous peer review process expected from ACS journals.
Open Access: There are diverse open-access options for publications in American Chemical Society journals. Please visit our Open Science Resource Center for more information.
How to Submit
- Log in to the ACS Publishing Center.
- Select the "Journals" tab.
- Choose Chemical Research in Toxicology.
- Click "Submit."
- Select your manuscript type, and, under "Special Issue Selection," choose “Toxicological Risks of Emerging Chemicals and Particles."
If you have any general questions regarding submission to this Special Issue, please contact the journal editorial office (eic@crt.acs.org).
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