This joint Virtual Special Issue will highlight the importance of structural biology in drug discovery and therapeutic development. Submit your manuscript by January 31, 2025.

A colorful molecular structure consisting of interconnected atoms represented by pink, purple, teal, and yellow spheres against a dark background.

In recent years, structure-based drug design has become increasingly important for medicinal chemistry researchers in their drug development campaigns. Structural biology not only provides information on drug function, but also identifies the activation mechanisms of specific targets in underlying diseases. In the context of drug discovery, structural biology provides us with the basis for identifying novel therapeutics, improving lead compound optimization, and understanding drug function.

The Journal of Medicinal Chemistry and ACS Medicinal Chemistry Letters are opening submissions for a Virtual Special Issue on “Structural Biology in Drug Discovery and Development.” For this Virtual Special, the Journal of Medicinal Chemistry will publish Perspectives, Articles, and Drug Annotations. ACS Medicinal Chemistry Letters welcomes Letters, Notes, Technical Notes, and Viewpoints. For more information on this Virtual Special Issue, read our joint Editorial on the topic.

Organizing Editors

David E. Heppner, Early Career Board, Journal of Medicinal Chemistry
University of Buffalo, United States

Simone V. Bigi-Botterill, Early Career Board, ACS Medicinal Chemistry Letters
Exscientia, United States

Andrew P. Riley, Early Career Board, ACS Medicinal Chemistry Letters
University of Illinois at Chicago, United States

Kelly Chibale, Editor-in-Chief, ACS Medicinal Chemistry Letters
University of Cape Town, South Africa

Craig W. Lindsley, Editor-in-Chief, Journal of Medicinal Chemistry
Vanderbilt University Medical Center, United States

Submission Instructions

Submissions are welcome through January 31, 2025.

To submit for this Special Issue:

  • Log in to the ACS Publishing Center.
  • Select the “Journals” tab.
  • Search for Journal of Medicinal Chemistry or ACS Medicinal Chemistry Letters.
  • Click "Submit."
  • Select your manuscript type, and, under "Special Issue Selection," choose "Structural Biology in Drug Discovery and Development."

Please consider the relevant Author Guidelines for the Journal of Medicinal Chemistry or ACS Medicinal Chemistry Letters for more information on submission requirements.

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