This Special Issue will highlight cutting-edge pharmaceutical science behind the development and translation of novel vaccine adjuvants. Submit your manuscript by April 30, 2027.

As vaccine development increasingly relies on sophisticated adjuvant systems to enhance the performance of modern antigens, new challenges have emerged in formulation, manufacturing, characterization, and product development.
This Special Issue of Molecular Pharmaceutics seeks submissions that advance the pharmaceutical science behind vaccine adjuvants, with an emphasis on translating complex adjuvant systems into stable, scalable, and clinically relevant products. We welcome submissions that provide insights into the design, production, analysis, and development of next-generation adjuvants, supporting the advancement of innovative vaccine technologies from discovery through commercialization.
Topics include, but are not limited to:
- Adjuvant formulation and design
- Physicochemical optimization
- Alternative delivery systems
- Controlled release and biodistribution
- Mixing technologies and scale-up
- Manufacturing process optimization
- Analytical characterization
- Stability and shelf-life prediction
- In vivo potency assessment
- Regulatory, safety, and translational strategies
For more information on this Special Issue, read our Call for Papers Editorial. Submit your manuscript by April 30, 2027.
Organizing Editors
Joe Vanderburgh, Guest Editor
Merck & Co., Inc., United States
Marco Blanco, Guest Editor
Merck & Co., Inc., United States
Aaron Esser-Kahn, Guest Editor
University of Chicago, United States
Submission Information
We welcome submissions for this Special Issue through April 30, 2027. For more information on submission requirements, please review the journal’s Author Guidelines.
Manuscript types considered for this Special Issue include Research Articles, Communications, Perspectives, and Reviews (by proposal only). All submissions will undergo the full, rigorous peer review process expected from ACS journals. Papers accepted for publication in this Special Issue will be available online ASAP (as soon as publishable). Once all accepted papers are published, they will be compiled on a dedicated landing page to form the Special Issue.
How to Submit
- Log in to the ACS Publishing Center.
- Select your manuscript type; upload your manuscript and related files.
- Review the title and abstract fields to confirm any pre-populated information has transferred correctly.
- Under “Special Issue Selection,” select Vaccine Adjuvant Process, Formulation, and Characterization.
- Confirm all other information is correct.
- Submit your article.
If you have any general questions regarding submission to this Special Issue, please contact taylor-office@mp.acs.org.
