There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five […]
There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention over the past year.
Read more of 2017’s most-read articles: Analytical | Applied | Biological | Materials Science & Engineering | Multidisciplinary | Physical
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ACS Catalysis
Catalysis by Supported Single Metal Atoms
ACS Catal., 2017, 7 (1), pp 34–59
DOI: 10.1021/acscatal.6b01534
Rational Design of High-Performance Phosphine Sulfonate Nickel Catalysts for Ethylene Polymerization and Copolymerization with Polar Monomers
Open access through ACS AuthorChoice
ACS Catal., 2017, 7 (2), pp 1308–1312
DOI: 10.1021/acscatal.6b03394
Superlative Scientific Writing
ACS Catal., 2017, 7 (3), pp 2218–2219
DOI: 10.1021/acscatal.7b00566
Kinetic Modeling of the Nickel-Catalyzed Esterification of Amides
Open access through Editors’ Choice
ACS Catal., 2017, 7 (7), pp 4381–4385
DOI: 10.1021/acscatal.7b01444
Visible-Light-Mediated Anti-Markovnikov Hydration of Olefins
Open access through Editors’ Choice
ACS Catal., 2017, 7 (2), pp 1432–1437
DOI: 10.1021/acscatal.6b03388
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ACS Combinatorial Science
An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening
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ACS Comb. Sci., 2017, 19 (3), pp 181–192
DOI: 10.1021/acscombsci.6b00192
Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening
ACS Comb. Sci., 2017, 19 (8), pp 524–532
DOI: 10.1021/acscombsci.7b00061
Rationally Designed Peptides and Peptidomimetics as Inhibitors of Amyloid-β (Aβ) Aggregation: Potential Therapeutics of Alzheimer’s Disease
ACS Comb. Sci., 2017, 19 (2), pp 55–80
DOI: 10.1021/acscombsci.6b00116
Automated Phase Mapping with AgileFD and its Application to Light Absorber Discovery in the V–Mn–Nb Oxide System
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ACS Comb. Sci., 2017, 19 (1), pp 37–46
DOI: 10.1021/acscombsci.6b00153
Technical Advances in Medicinal Chemistry
ACS Comb. Sci., 2017, 19 (5), pp 277–278
DOI: 10.1021/acscombsci.7b00053
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INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology
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ACS Med. Chem. Lett., 2017, 8 (5), pp 486–491
DOI: 10.1021/acsmedchemlett.6b00391
Medicinal Chemistry: Where Are All the Women?
ACS Med. Chem. Lett., 2017, 8 (9), pp 900–902
DOI: 10.1021/acsmedchemlett.7b00321
Practical High-Throughput Experimentation for Chemists
Open access through ACS AuthorChoice
ACS Med. Chem. Lett., 2017, 8 (6), pp 601–607
DOI: 10.1021/acsmedchemlett.7b00165
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
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ACS Med. Chem. Lett., 2017, 8 (3), pp 321–326
DOI: 10.1021/acsmedchemlett.6b00491
Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties
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ACS Med. Chem. Lett., 2017, 8 (6), pp 608–613
DOI: 10.1021/acsmedchemlett.7b00103
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In Vivo Delivery of CRISPR/Cas9 for Therapeutic Gene Editing: Progress and Challenges
Bioconjugate Chem., 2017, 28 (4), pp 880–884
DOI: 10.1021/acs.bioconjchem.7b00057
Site-Specific Dual Functionalization of Cysteine Residue in Peptides and Proteins with 2-Azidoacrylates
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Bioconjugate Chem., 2017, 28 (4), pp 897–902
DOI: 10.1021/acs.bioconjchem.7b00024
89Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89Zr Radiochemistry
Open access through ACS AuthorChoice
Bioconjugate Chem., 2017, 28 (9), pp 2211–2223
DOI: 10.1021/acs.bioconjchem.7b00325
Versatile Site-Selective Protein Reaction Guided by WW Domain–Peptide Motif Interaction
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Bioconjugate Chem., 2017, 28 (8), pp 2199–2205
DOI: 10.1021/acs.bioconjchem.7b00334
Biointerfacing and Applications of Cell Membrane-Coated Nanoparticles
This article is part of the Interfacing Inorganic Nanoparticles with Biology special issue.
Bioconjugate Chem., 2017, 28 (1), pp 23–32
DOI: 10.1021/acs.bioconjchem.6b00569
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Inorganic Chemistry
Metal–Metal Bonds: From Fundamentals to Applications
Inorg. Chem., 2017, 56 (14), pp 7577–7581
DOI: 10.1021/acs.inorgchem.7b01330
Tris(pentafluorophenyl)borane and Beyond: Modern Advances in Borylation Chemistry
Open access through ACS AuthorChoice
Inorg. Chem., 2017, 56 (15), pp 8627–8643
DOI: 10.1021/acs.inorgchem.6b02911
Luminescent Cyclometalated Gold(III) Alkyl Complexes: Photophysical and Photochemical Properties
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Inorg. Chem., 2017, 56 (9), pp 5046–5059
DOI: 10.1021/acs.inorgchem.7b00180
The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications
Inorg. Chem., 2017, 56 (24), pp 14715–14729
DOI: 10.1021/acs.inorgchem.7b02599
From Positive to Negative Zero-Field Splitting in a Series of Strongly Magnetically Anisotropic Mononuclear Metal Complexes
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Inorg. Chem., 2017, 56 (24), pp 14809–14822
DOI: 10.1021/acs.inorgchem.7b01861
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Journal of Medicinal Chemistry
The Essential Medicinal Chemistry of Curcumin
Open access through Editors’ Choice
J. Med. Chem., 2017, 60 (5), pp 1620–1637
DOI: 10.1021/acs.jmedchem.6b00975
Synthetic Approaches to the New Drugs Approved During 2015
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J. Med. Chem., 2017, 60 (15), pp 6480–6515
DOI: 10.1021/acs.jmedchem.7b00010
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
J. Med. Chem., 2017, 60 (4), pp 1247–1261
DOI: 10.1021/acs.jmedchem.6b01751
A Versatile Method to Determine the Cellular Bioavailability of Small-Molecule Inhibitors
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J. Med. Chem., 2017, 60 (1), pp 157–169
DOI: 10.1021/acs.jmedchem.6b00923
How Big Is Too Big for Cell Permeability?
J. Med. Chem., 2017, 60 (5), pp 1662–1664
DOI: 10.1021/acs.jmedchem.7b00237
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Journal of Natural Products
Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community
Open access through ACS AuthorChoice
J. Nat. Prod., 2017, 80 (3), pp 756–770
DOI: 10.1021/acs.jnatprod.6b01085
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects
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J. Nat. Prod., 2017, 80 (3), pp 740–755
DOI: 10.1021/acs.jnatprod.6b00970
The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture
J. Nat. Prod., 2017, 80 (4), pp 1150–1160
DOI: 10.1021/acs.jnatprod.7b00133
Bioinspired Indole Prenylation Reactions in Water
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J. Nat. Prod., 2017, 80 (8), pp 2371–2378
DOI: 10.1021/acs.jnatprod.7b00464
Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors
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J. Nat. Prod., 2017, 80 (3), pp 692–698
DOI: 10.1021/acs.jnatprod.6b01006
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The Journal of Organic Chemistry
Removal of Triphenylphosphine Oxide by Precipitation with Zinc Chloride in Polar Solvents
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J. Org. Chem., 2017, 82 (19), pp 9931–9936
DOI: 10.1021/acs.joc.7b00459
Natural Products and Their Mimics as Targets of Opportunity for Discovery
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J. Org. Chem., 2017, 82 (20), pp 10757–10794
DOI: 10.1021/acs.joc.7b01368
The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry–Biology Interface
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J. Org. Chem., 2017, 82 (23), pp 11961–11980
DOI: 10.1021/acs.joc.7b02088
Chlorophyll-Catalyzed Visible-Light-Mediated Synthesis of Tetrahydroquinolines from N,N-Dimethylanilines and Maleimides
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J. Org. Chem., 2017, 82 (4), pp 1888–1894
DOI: 10.1021/acs.joc.6b03034
Aliphatic C–H Bond Iodination by a N-Iodoamide and Isolation of an Elusive N-Amidyl Radical
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J. Org. Chem., 2017, 82 (14), pp 7093–7100
DOI: 10.1021/acs.joc.7b00557
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Molecular Pharmaceutics
Lipid–Drug Conjugate for Enhancing Drug Delivery
This article is part of the Bioconjugate Therapeutics special issue.
Mol. Pharmaceutics, 2017, 14 (5), pp 1325–1338
DOI: 10.1021/acs.molpharmaceut.6b01027
Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance
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Mol. Pharmaceutics, 2017, 14 (5), pp 1623–1633
DOI: 10.1021/acs.molpharmaceut.6b01091
Encapsulation of Ibuprofen in CD-MOF and Related Bioavailability Studies
Mol. Pharmaceutics, 2017, 14 (5), pp 1831–1839
DOI: 10.1021/acs.molpharmaceut.7b00168
Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine
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Mol. Pharmaceutics, 2017, 14 (7), pp 2245–2253
DOI: 10.1021/acs.molpharmaceut.7b00076
Biocompatible Injectable Hydrogel with Potent Wound Healing and Antibacterial Properties
Mol. Pharmaceutics, 2017, 14 (4), pp 1218–1230
DOI: 10.1021/acs.molpharmaceut.6b01104
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Organic Letters
Synthetic Study toward Total Synthesis of (±)-Germine: Synthesis of (±)-4-Methylenegermine
Org. Lett., 2017, 19 (19), pp 5150–5153
DOI: 10.1021/acs.orglett.7b02434
Enantioselective Total Synthesis of (+)-Sieboldine A
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Org. Lett., 2017, 19 (2), pp 320–323
DOI: 10.1021/acs.orglett.6b03416
B(C6F5)3-Catalyzed Michael Reactions: Aromatic C–H as Nucleophiles
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Org. Lett., 2017, 19 (10), pp 2568–2571
DOI: 10.1021/acs.orglett.7b00720
Enantioselective Synthesis of (−)-Acetylapoaranotin
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Org. Lett., 2017, 19 (7), pp 1698–1701
DOI: 10.1021/acs.orglett.7b00418
Pd-Catalyzed Ortho C–H Hydroxylation of Benzaldehydes Using a Transient Directing Group
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Org. Lett., 2017, 19 (23), pp 6280–6283
DOI: 10.1021/acs.orglett.7b02906
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Organic Process Research & Development
BMS-663068: Another Quiet Victory for Chemistry
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Org. Process Res. Dev., 2017, 21 (8), pp 1091–1094
DOI: 10.1021/acs.oprd.7b00208
General Principles and Strategies for Salting-Out Informed by the Hofmeister Series
Open access through ACS AuthorChoice
Org. Process Res. Dev., 2017, 21 (9), pp 1355–1370
DOI: 10.1021/acs.oprd.7b00197
One-Step Continuous Flow Synthesis of Antifungal WHO Essential Medicine Flucytosine Using Fluorine
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Org. Process Res. Dev., 2017, 21 (2), pp 273–276
DOI: 10.1021/acs.oprd.6b00420
Some Items of Interest to Process R&D Chemists and Engineers
Org. Process Res. Dev., 2017, 21 (6), pp 789–799
DOI: 10.1021/acs.oprd.7b00193
Simple and Versatile Laboratory Scale CSTR for Multiphasic Continuous-Flow Chemistry and Long Residence Times
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Org. Process Res. Dev., 2017, 21 (9), pp 1294–1301
DOI: 10.1021/acs.oprd.7b00173
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Organometallics
Synthesis, Reactivity, and Catalytic Applications of Isolable (NHC)Cu(CHF2) Complexes
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Organometallics, 2017, 36 (7), pp 1220–1223
DOI: 10.1021/acs.organomet.7b00025
A New Mode of Operation of Pd-NHC Systems Studied in a Catalytic Mizoroki–Heck Reaction
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Organometallics, 2017, 36 (10), pp 1981–1992
DOI: 10.1021/acs.organomet.7b00184
Toxicity of Metal Compounds: Knowledge and Myths
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Organometallics, 2017, 36 (21), pp 4071–4090
DOI: 10.1021/acs.organomet.7b00605
Evaluating 1,1′-Bis(phosphino)ferrocene Ancillary Ligand Variants in the Nickel-Catalyzed C–N Cross-Coupling of (Hetero)aryl Chlorides
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Organometallics, 2017, 36 (3), pp 679–686
DOI: 10.1021/acs.organomet.6b00885
Flipping the Oxidation State Formalism: Charge Distribution in Organometallic Complexes As Reported by Carbon Monoxide
Organometallics, 2017, 36 (3), pp 622–631
DOI: 10.1021/acs.organomet.6b00820
