Here, we discover the most-read organic/inorganic chemistry articles October 2019, including research, reviews, perspectives, and editorial pieces.
There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in October 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.
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Read more of October’s most-read articles.
ACS Catalysis
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Recent Advances in Pyridinium Salts as Radical Reservoirs in Organic Synthesis
DOI: 10.1021/acscatal.9b03084
Catalysis of Organic Reactions through Halogen Bonding
DOI: 10.1021/acscatal.9b02894
Nickel/Cobalt-Catalyzed C(sp3)–C(sp3) Cross-Coupling of Alkyl Halides with Alkyl Tosylates
DOI: 10.1021/acscatal.9b03352
Gold-Catalyzed C–H Functionalization with Aryl Germanes
DOI: 10.1021/acscatal.9b02841
A General Route to Bicyclo[1.1.1]pentanes through Photoredox Catalysis
DOI: 10.1021/acscatal.9b03190
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ACS Combinatorial Science
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A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis
DOI: 10.1021/acscombsci.9b00113
Visible-Light-Initiated One-Pot, Three-Component Synthesis of 2-Amino-4H-pyran-3,5-dicarbonitrile Derivatives
DOI: 10.1021/acscombsci.9b00124
Multicomponent Approach to Libraries of Substituted Dihydroorotic Acid Amides
DOI: 10.1021/acscombsci.9b00144
Enzyme Degassing for Oxygen-Sensitive Reactions in Open Vessels of an Automated Parallel Synthesizer: RAFT Polymerizations
DOI: 10.1021/acscombsci.9b00082
Scanning Electrochemical Flow Cell with Online Mass Spectroscopy for Accelerated Screening of Carbon Dioxide Reduction Electrocatalysts
DOI: 10.1021/acscombsci.9b00130
ACS Medicinal Chemistry Letters
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PROTAC-Mediated Degradation of Estrogen Receptor in the Treatment of Cancer
DOI: 10.1021/acsmedchemlett.9b00397
Synthesis and Evaluation of Camptothecin Antibody–Drug Conjugates
Open Access through ACS AuthorChoice
DOI: 10.1021/acsmedchemlett.9b00301
“AβTau”, Lobby or Religion?
DOI: 10.1021/acsmedchemlett.9b00439
PROTAC Degradation of IRAK4 for the Treatment of Cancer
DOI: 10.1021/acsmedchemlett.9b00423
Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing
Open Access through ACS AuthorChoice
DOI: 10.1021/acsmedchemlett.9b00310
Bioconjugate Chemistry
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Antibody–Oligonucleotide Conjugates as Therapeutic, Imaging, and Detection Agents
DOI: 10.1021/acs.bioconjchem.9b00306
Dual Site-Specific Labeling of an Antibody Fragment through Sortase A and π-Clamp Conjugation
DOI: 10.1021/acs.bioconjchem.9b00639
Targeted, Stimuli-Responsive, and Theranostic 19F Magnetic Resonance Imaging Probes
DOI: 10.1021/acs.bioconjchem.9b00582
Zwitterionic Modification of Nanomaterials for Improved Diagnosis of Cancer Cells
DOI: 10.1021/acs.bioconjchem.9b00543
Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention
DOI: 10.1021/acs.bioconjchem.9b00587
Inorganic Chemistry
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The Chemistry Women Mentorship Network (ChemWMN): A Tool for Creating Critical Mass in Academic Chemistry
DOI: 10.1021/acs.inorgchem.9b02707
Metals in Biology: From Metallomics to Trafficking
DOI: 10.1021/acs.inorgchem.9b02965
Structure and Properties of a Five-Coordinate Nickel(II) Porphyrin
DOI: 10.1021/acs.inorgchem.9b00348
Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry
DOI: 10.1021/acs.inorgchem.9b01221
Spectroscopic X-ray and Mössbauer Characterization of M6 and M5 Iron(Molybdenum)-Carbonyl Carbide Clusters: High Carbide-Iron Covalency Enhances Local Iron Site Electron Density Despite Cluster Oxidation
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.inorgchem.9b01870
Journal of Medicinal Chemistry
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Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor
DOI: 10.1021/acs.jmedchem.9b01234
Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune Diseases
DOI: 10.1021/acs.jmedchem.9b01612
Antibiotic Adjuvants: Make Antibiotics Great Again!
DOI: 10.1021/acs.jmedchem.8b01781
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
DOI: 10.1021/acs.jmedchem.9b00444
Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases
DOI: 10.1021/acs.jmedchem.9b00533
Journal of Natural Products
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Nectriatide, a Potentiator of Amphotericin B Activity from Nectriaceae sp. BF-0114
DOI: 10.1021/acs.jnatprod.8b01056
Constituents from the Leaves of Tetraena mongolica and Their Protective Activity in HEK 293t Cells Damaged by CdCl2
DOI: 10.1021/acs.jnatprod.9b00212
Anti-Lymphangiogenic Alkaloids from the Zoanthid Zoanthus vietnamensis Collected in Taiwan
DOI: 10.1021/acs.jnatprod.9b00451
Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon
DOI: 10.1021/acs.jnatprod.9b00522
Tripterfordins A–O, Dihydro-β-agarofuran Sesquiterpenoids from the Leaves of Tripterygium wilfordii
DOI: 10.1021/acs.jnatprod.9b00089
The Journal of Organic Chemistry
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The Breadth and Depth of C–H Functionalization
DOI: 10.1021/acs.joc.9b02663
Axial Chirality at the Boron–Carbon Bond: Synthesis, Stereodynamic Analysis, and Atropisomeric Resolution of 6-Aryl-5,6-dihydrodibenzo[c,e][1,2]azaborinines
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.joc.9b01550
N-Amino-7-azaindole as the N,N′-Bidentate Directing Group: Ruthenium-Catalyzed Oxidative Annulation of N-(7-Azaindole)benzamides with Alkynes via C–H Bond Activation
DOI: 10.1021/acs.joc.9b01598
En Route to Intermolecular Cross-Dehydrogenative Coupling Reactions
DOI: 10.1021/acs.joc.9b01704
Development of an Imine Chaperone for Selective C–H Functionalization of Alcohols via Radical Relay
DOI: 10.1021/acs.joc.9b02052
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Molecular Pharmaceutics
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Use of Terahertz-Raman Spectroscopy to Determine Solubility of the Crystalline Active Pharmaceutical Ingredient in Polymeric Matrices during Hot Melt Extrusion
Open Access through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00703
Prediction of Bioequivalence and Food Effect Using Flux- and Solubility-Based Methods
Open Access through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00406
Recent Advances in Understanding the Micro- and Nanoscale Phenomena of Amorphous Solid Dispersions
DOI: 10.1021/acs.molpharmaceut.9b00601
Scale-Independent Microfluidic Production of Cationic Liposomal Adjuvants and Development of Enhanced Lymphatic Targeting Strategies
Open Access through ACS AuthorChoice
DOI: 10.1021/acs.molpharmaceut.9b00730
From Target to Drug: Generative Modeling for the Multimodal Structure-Based Ligand Design
DOI: 10.1021/acs.molpharmaceut.9b00634
Organic Letters
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Characterization of Leptazolines A–D, Polar Oxazolines from the Cyanobacterium Leptolyngbya sp., Reveals a Glitch with the “Willoughby–Hoye” Scripts for Calculating NMR Chemical Shifts
DOI: 10.1021/acs.orglett.9b03216
Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes
DOI: 10.1021/acs.orglett.9b02779
Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent
DOI: 10.1021/acs.orglett.9b03024
Intermolecular Phosphite-Mediated Radical Desulfurative Alkene Alkylation Using Thiols
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.orglett.9b03018
Visible-Light-Induced Copper-Catalyzed Intermolecular Markovnikov Hydroamination of Alkenes
DOI: 10.1021/acs.orglett.9b02863
Organic Process Research & Development
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Some Items of Interest to Process R&D Chemists and Engineers
DOI: 10.1021/acs.oprd.9b00412
Explosion Hazards of Sodium Hydride in Dimethyl Sulfoxide, N,N-Dimethylformamide, and N,N-Dimethylacetamide
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.oprd.9b00276
The Role of Process Chemistry in Providing Healthy Food for a Healthy and Growing Planet
DOI: 10.1021/acs.oprd.9b00383
Applications of the 12 Principles of Green Chemistry in the Crop Protection Industry
DOI: 10.1021/acs.oprd.9b00305
Development of a Scalable Process for the Insecticidal Candidate Tyclopyrazoflor. Part 1. Evaluation of [3 + 2] Cyclization Strategies to 3-(3-Chloro-1H-pyrazol-1-yl)pyridine
DOI: 10.1021/acs.oprd.9b00127
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Organometallics
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Isolation and Characterization of a Homoleptic Tetramethylcobalt(III) Distorted Square-Planar Complex
Open Access Through ACS Editors’ Choice
DOI: 10.1021/acs.organomet.9b00387
Asymmetric Synthesis Enabled by Organometallic Complexes
DOI: 10.1021/acs.organomet.9b00627
Synthesis, Structure, and Reactivity of an NHC Silyl Gold(I) Complex
DOI: 10.1021/acs.organomet.9b00574
Synthesis of (MeCN)2Pd(CF3)OTs, a General Precursor to Palladium(II) Trifluoromethyl Complexes LPd(CF3)X
DOI: 10.1021/acs.organomet.9b00516
Dioxo-, Oxo-imido-, and Bis-imido-Molybdenum(VI) Complexes with a Bis-phenolate-NHC Ligand
DOI: 10.1021/acs.organomet.9b00472
