What were chemists reading in March of 2017? To find out, we’ve compiled lists of the five most-read chemistry articles that appeared in each organic chemistry and inorganic chemistry ACS Publications journal in March 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t […]
What were chemists reading in March of 2017? To find out, we’ve compiled lists of the five most-read chemistry articles that appeared in each organic chemistry and inorganic chemistry ACS Publications journal in March 2017, including research, reviews, perspectives and editorial pieces. These lists were not chosen by the journals’ editors. The lists also don’t take other factors, such as citations, into account. This article should not be taken as a “best of” compilation, but rather as an interesting perspective on where the chemistry community allocated their attention recently. Don’t see your favorite paper on the list? Include it in the comments below.
Read more great March 2017 Chemistry research: Analytical Chemistry | Applied Chemistry | Biological Chemistry | Materials Science & Engineering | Multidisciplinary Chemistry | Physical Chemistry
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ACS Catalysis
Superlative Scientific Writing
ACS Catal., 2017, 7 (3), pp 2218–2219
DOI: 10.1021/acscatal.7b00566
A Viewpoint on Chemical Reductions of Carbon–Oxygen Bonds in Renewable Feedstocks Including CO2 and Biomass
ACS Catal., 2017, 7 (3), pp 2107–2115
DOI: 10.1021/acscatal.6b03581
Electrochemical Reduction of CO2 Catalyzed by Fe-N-C Materials: A Structure–Selectivity Study
ACS Catal., 2017, 7 (3), pp 1520–1525
DOI: 10.1021/acscatal.6b03353
Silver-Catalyzed Anti-Markovnikov Hydroxyfluorination of Styrenes
ACS Catal., 2017, 7 (3), pp 1606–1609
DOI: 10.1021/acscatal.6b03529
Ruthenium-Catalyzed Direct Hydroxymethylation of Aryl C–H Bonds
ACS Catal., 2017, 7 (3), pp 2213–2217
DOI: 10.1021/acscatal.7b00078
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ACS Combinatorial Science
An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening
Open access through ACS Editors’ Choice
ACS Comb. Sci., 2017, 19 (3), pp 181–192
DOI: 10.1021/acscombsci.6b00192
Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2
ACS Comb. Sci., 2017, 19 (3), pp 161–172
DOI: 10.1021/acscombsci.6b00174
Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations
Open access through ACS AuthorChoice
ACS Comb. Sci., 2017, 19 (3), pp 193–198
DOI: 10.1021/acscombsci.7b00009
Fast and Facile Synthesis of 4-Nitrophenyl 2-Azidoethylcarbamate Derivatives from N-Fmoc-Protected α-Amino Acids as Activated Building Blocks for Urea Moiety-Containing Compound Library
ACS Comb. Sci., 2017, 19 (3), pp 131–136
DOI: 10.1021/acscombsci.6b00160
Multicomponent Assembly of the Kinesin Spindle Protein Inhibitor CPUYJ039 and Analogues as Antimitotic Agents
ACS Comb. Sci., 2017, 19 (3), pp 153–160
DOI: 10.1021/acscombsci.6b00166
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ACS Medicinal Chemistry Letters
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
Open access through ACS Editors’ Choice
ACS Med. Chem. Lett., 2017, 8 (3), pp 321–326
DOI: 10.1021/acsmedchemlett.6b00491
Curcumin May Defy Medicinal Chemists
ACS Med. Chem. Lett., 2017, 8 (3), pp 274–274
DOI: 10.1021/acsmedchemlett.7b00051
Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites
Open access through ACS Editors’ Choice
ACS Med. Chem. Lett., 2017, 8 (3), pp 350–354
DOI: 10.1021/acsmedchemlett.7b00011
Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach
ACS Med. Chem. Lett., 2017, 8 (3), pp 338–343
DOI: 10.1021/acsmedchemlett.6b00519
Editorial: Medicinal Chemistry Research in India
ACS Med. Chem. Lett., 2017, 8 (3), pp 270–272
DOI: 10.1021/acsmedchemlett.7b00064
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Bioconjugate Chemistry
Peptide Conjugates for Biological Applications
Open access through ACS AuthorChoice
Bioconjugate Chem., 2017, 28 (3), pp 689–690
DOI: 10.1021/acs.bioconjchem.7b00102
Designing Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes
Bioconjugate Chem., 2017, 28 (3), pp 793–804
DOI: 10.1021/acs.bioconjchem.6b00725
Functional Modification of Thioether Groups in Peptides, Polypeptides, and Proteins
Bioconjugate Chem., 2017, 28 (3), pp 691–700
DOI: 10.1021/acs.bioconjchem.6b00696
Self-Assembly of Peptide Bioconjugates: Selected Recent Research Highlights
Open access through ACS AuthorChoice
Bioconjugate Chem., 2017, 28 (3), pp 731–739
DOI: 10.1021/acs.bioconjchem.6b00284
Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins
Bioconjugate Chem., 2017, 28 (3), pp 713–723
DOI: 10.1021/acs.bioconjchem.6b00652
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Inorganic Chemistry
Giant Exchange Coupling Evidenced with a Magnetization Jump at 52 T for a Gadolinium-Nitroxide Chelate
Open access through ACS Editors’ Choice
Inorg. Chem., 2017, 56 (6), pp 3310–3314
DOI: 10.1021/acs.inorgchem.6b02685
Incorporation of Pyrazine and Bipyridine Linkers with High-Spin Fe(II) and Co(II) in a Metal–Organic Framework
Inorg. Chem., 2017, 56 (6), pp 3349–3356
DOI: 10.1021/acs.inorgchem.6b02883
Quantitation of the THF Content in Fe[N(SiMe3)2]2·xTHF
Open access through ACS AuthorChoice
Inorg. Chem., 2017, 56 (6), pp 3140–3143
DOI: 10.1021/acs.inorgchem.7b00056
Polar Ketone-Functionalized Metal–Organic Framework Showing a High CO2 Adsorption Performance
Inorg. Chem., 2017, 56 (5), pp 2363–2366
DOI: 10.1021/acs.inorgchem.6b02660
Oxoiron(IV) Tetramethylcyclam Complexes with Axial Carboxylate Ligands: Effect of Tethering the Carboxylate on Reactivity
Inorg. Chem., 2017, 56 (6), pp 3287–3301
DOI: 10.1021/acs.inorgchem.6b02659
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Journal of Medicinal Chemistry
The Essential Medicinal Chemistry of Curcumin
Open access through ACS Editors’ Choice
J. Med. Chem., 2017, 60 (5), pp 1620–1637
DOI: 10.1021/acs.jmedchem.6b00975
How Big Is Too Big for Cell Permeability?
J. Med. Chem., 2017, 60 (5), pp 1662–1664
DOI: 10.1021/acs.jmedchem.7b00237
The Ecstasy and Agony of Assay Interference Compounds
J. Med. Chem., 2017, 60 (6), pp 2165–2168
DOI: 10.1021/acs.jmedchem.7b00229
Combining Molecular Scaffolds from FDA Approved Drugs: Application to Drug Discovery
J. Med. Chem., 2017, 60 (5), pp 1638–1647
DOI: 10.1021/acs.jmedchem.6b01367
Design, Synthesis, and Evaluation of a Novel Series of Oxadiazine Gamma Secretase Modulators for Familial Alzheimer’s Disease
J. Med. Chem., 2017, 60 (6), pp 2383–2400
DOI: 10.1021/acs.jmedchem.6b01620
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Journal of Natural Products
Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community
Open access through ACS AuthorChoice
J. Nat. Prod., 2017, 80 (3), pp 756–770
DOI: 10.1021/acs.jnatprod.6b01085
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects
Open access through ACS Editors’ Choice
J. Nat. Prod., 2017, 80 (3), pp 740–755
DOI: 10.1021/acs.jnatprod.6b00970
Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors
Open access through ACS Editors’ Choice
J. Nat. Prod., 2017, 80 (3), pp 692–698
DOI: 10.1021/acs.jnatprod.6b01006
Opportunistic Sampling of Roadkill as an Entry Point to Accessing Natural Products Assembled by Bacteria Associated with Non-anthropoidal Mammalian Microbiomes
Open access through ACS AuthorChoice
J. Nat. Prod., 2017, 80 (3), pp 598–608
DOI: 10.1021/acs.jnatprod.6b00772
Protoxenicins A and B, Cytotoxic Long-Chain Acylated Xenicanes from the Soft Coral Protodendron repens
This article is part of the Special Issue in Honor of Phil Crews special issue.
J. Nat. Prod., 2017, 80 (3), pp 713–719
DOI: 10.1021/acs.jnatprod.7b00046
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The Journal of Organic Chemistry
The Conversion of tert-Butyl Esters to Acid Chlorides Using Thionyl Chloride
J. Org. Chem., 2017, 82 (6), pp 3245–3251
DOI: 10.1021/acs.joc.6b02931
CuBr-Catalyzed Aerobic Decarboxylative Cycloaddition for the Synthesis of Indolizines under Solvent-Free Conditions
J. Org. Chem., 2017, 82 (6), pp 2835–2842
DOI: 10.1021/acs.joc.6b02455
Transition-Metal-Free Oxidative Decarboxylative Cross Coupling of α,β-Unsaturated Carboxylic Acids with Cyclic Ethers under Air Conditions: Mild Synthesis of α-Oxyalkyl Ketones
J. Org. Chem., 2017, 82 (6), pp 2965–2971
DOI: 10.1021/acs.joc.6b02993
Total Synthesis of (−)-Marinisporolide C
J. Org. Chem., 2017, 82 (6), pp 3019–3045
DOI: 10.1021/acs.joc.7b00023
One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
J. Org. Chem., 2017, 82 (6), pp 3011–3018
DOI: 10.1021/acs.joc.6b03084
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Molecular Pharmaceutics
Breast Cancer Targeting Peptide Binds Keratin 1: A New Molecular Marker for Targeted Drug Delivery to Breast Cancer
Mol. Pharmaceutics, 2017, 14 (3), pp 593–604
DOI: 10.1021/acs.molpharmaceut.6b00652
Mitochondria and Nucleus Dual Delivery System To Overcome DOX Resistance
Mol. Pharmaceutics, 2017, 14 (3), pp 746–756
DOI: 10.1021/acs.molpharmaceut.6b01016
Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukemia: Physicochemical Characteristics, in Vitro Mechanistic Studies, and ex Vivo Patient Derived Therapeutic Efficacy
Mol. Pharmaceutics, 2017, 14 (3), pp 940–952
DOI: 10.1021/acs.molpharmaceut.6b01150
Recent Advances in Nonlinear Optical Analyses of Pharmaceutical Materials in the Solid State
Mol. Pharmaceutics, 2017, 14 (3), pp 555–565
DOI: 10.1021/acs.molpharmaceut.6b00809
Biocompatible Reduction and pH Dual-Responsive Core Cross-Linked Micelles Based on Multifunctional Amphiphilic Linear–Hyperbranched Copolymer for Controlled Anticancer Drug Delivery
Mol. Pharmaceutics, 2017, 14 (3), pp 799–807
DOI: 10.1021/acs.molpharmaceut.6b01051
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Organic Letters
trans-Aminoboration across Internal Alkynes Catalyzed by B(C6F5)3 for the Synthesis of Borylated Indoles
Open access through ACS Editor’s Choice
Org. Lett., 2017, 19 (6), pp 1462–1465
DOI: 10.1021/acs.orglett.7b00437
Silver-Catalyzed C(sp3)–H Chlorination
Org. Lett., 2017, 19 (6), pp 1430–1433
DOI: 10.1021/acs.orglett.7b00367
Palladium-Catalyzed Direct Annulation of Benzoic Acids with Phenols to Synthesize Dibenzopyranones
Org. Lett., 2017, 19 (6), pp 1326–1329
DOI: 10.1021/acs.orglett.7b00177
C–H Activation under the Guise of Diels–Alder Reaction: Annulation toward the Synthesis of Benzo[e]isoindole-1,3-diones
Org. Lett., 2017, 19 (6), pp 1270–1273
DOI: 10.1021/acs.orglett.6b03757
Synthesis of Trifluoromethylated Naphthoquinones via Copper-Catalyzed Cascade Trifluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes
Org. Lett., 2017, 19 (6), pp 1302–1305
DOI: 10.1021/acs.orglett.7b00095
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Organic Process Research & Development
Some Items of Interest to Process R&D Chemists and Engineers
Org. Process Res. Dev., 2017, 21 (3), pp 279–291
DOI: 10.1021/acs.oprd.7b00057
Stereochemical Aspects of T3P Amidations
Org. Process Res. Dev., 2017, 21 (3), pp 399–407
DOI: 10.1021/acs.oprd.7b00046
Development of a Practical Synthesis of ERK Inhibitor GDC-0994
Org. Process Res. Dev., 2017, 21 (3), pp 387–398
DOI: 10.1021/acs.oprd.7b00006
The Pharmaceutical Drying Unit Operation: An Industry Perspective on Advancing the Science and Development Approach for Scale-Up and Technology Transfer
Org. Process Res. Dev., 2017, 21 (3), pp 420–429
DOI: 10.1021/acs.oprd.6b00406
A Practical and Scalable Synthesis of a Glucokinase Activator via Diastereomeric Resolution and Palladium-Catalyzed C–N Coupling Reaction
Org. Process Res. Dev., 2017, 21 (3), pp 346–356
DOI: 10.1021/acs.oprd.6b00415
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Organometallics
Iridium and Ruthenium Complexes of N-Heterocyclic Carbene- and Pyridinol-Derived Chelates as Catalysts for Aqueous Carbon Dioxide Hydrogenation and Formic Acid Dehydrogenation: The Role of the Alkali Metal
Organometallics, 2017, 36 (6), pp 1091–1106
DOI: 10.1021/acs.organomet.6b00806
A Cationic N-Heterocyclic Carbene Containing an Ammonium Moiety
Organometallics, 2017, 36 (5), pp 1049–1055
DOI: 10.1021/acs.organomet.7b00017
Synthesis and Structures of NCN Pincer-Type Ruthenium and Iridium Complexes Bearing Protic Pyrazole Arms
Organometallics, 2017, 36 (6), pp 1188–1195
DOI: 10.1021/acs.organomet.7b00065
Nickel(II) Complexes of Highly σ-Donating Cyclic (Alkyl)(Amino)- and Malonate-Carbenes: Syntheses and Catalytic Studies
Organometallics, 2017, 36 (6), pp 1113–1121
DOI: 10.1021/acs.organomet.6b00906
Alane-Centered Ring Expansion of N-Heterocyclic Carbenes
Organometallics, 2017, 36 (6), pp 1173–1178
DOI: 10.1021/acs.organomet.7b00056
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