Organic chemistry plays a central role in drug development, biotechnology, materials science, and wide range of other fields. In our daily lives, applications of organic chemistry are ubiquitous. The collection of articles featured here illustrates the broad scope and high quality of organic chemistry published in the journals of the American Chemical Society. Many of […]
Organic chemistry plays a central role in drug development, biotechnology, materials science, and wide range of other fields. In our daily lives, applications of organic chemistry are ubiquitous. The collection of articles featured here illustrates the broad scope and high quality of organic chemistry published in the journals of the American Chemical Society. Many of the authors of these articles will be presenting their research results at Pacifichem 2015, highlighting developments in bond activation, organocatalysis, green chemistry, supramolecular chemistry, natural products, process development, and more.
ACS Catalysis
Mechanistic Studies of Gold and Palladium Cooperative Dual-Catalytic Cross-Coupling Systems
Mohammad Al-Amin, Katrina E. Roth, and Suzanne A. Blum
ACS Catalysis 2014 4 (2), 622-629
Synthesis of Carbazoles by a Merged Visible Light Photoredox and Palladium-Catalyzed Process
Sungkyu Choi, Tanmay Chatterjee, Won Joon Choi, Youngmin You, and Eun Jin Cho
ACS Catalysis 2015 5 (8), 4796-4802
Recent Applications of Organic Dyes as Photoredox Catalysts in Organic Synthesis
David A. Nicewicz and Tien M. Nguyen
ACS Catalysis 2014 4 (1), 355-360
ACS Chemical Biology
Anatomy of beta-Strands at Protein-Protein Interfaces
Andrew M. Watkins and Paramjit S. Arora
ACS Chemical Biology 2014 9 (8), 1747-1754
Synthetic Antibodies with a Human Framework That Protect Mice from Lethal Sudan Ebolavirus Challenge
Gang Chen, Jayne F. Koellhoffer, Samantha E. Zak, Julia C. Frei, Nina Liu, Hua Long, Wei Ye, Kaajal Nagar, Guohua Pan, Kartik Chandran, John M. Dye, Sachdev S. Sidhu, and Jonathan R. Lai
ACS Chemical Biology 2014 9 (10), 2263-2273
Protein Kinase C delta Is a Therapeutic Target in Malignant Melanoma with NRAS Mutation
Asami Takashima, Brandon English, Zhihong Chen, Juxiang Cao, Rutao Cui, Robert M. Williams, and Douglas V. Faller
ACS Chemical Biology 2014 9 (4), 1003-1014
Crystal Growth & Design
Polymorphism in a Sulfamethoxazole Derivative: Coexistence of Five Polymorphs in Methanol at Room Temperature
Muhammad Nawaz Tahir, Zahid Shafiq, Hazoor Ahmad Shad, Zia-ur-Rehman, Abdul Karim, and Muhammad Moazzam Naseer
Crystal Growth & Design 2015 15 (10), 4750-4755
Inorganic Chemistry
Carbon- Hydrogen Bond Activation, C-N Bond Coupling, and Cycloaddition Reactivity of a Three-Coordinate Nickel Complex Featuring a Terminal Imido Ligand
Daniel J. Mindiola, Rory Waterman, Vlad M. Iluc, Thomas R. Cundari, and Gregory L. Hillhouse
Inorganic Chemistry 2014 53 (24), 13227-13238
Journal of Organic Chemistry
A Perspective on Physical Organic Chemistry
Matthew S. Platz
The Journal of Organic Chemistry 2014 79 (6), 2341-2353
Organotrifluoroborates: Another Branch of the Mighty Oak
Gary A. Molander
The Journal of Organic Chemistry 2015 80 (16), 7837-7848
Total Synthesis of Brazilin
Youngeun Jung and Ikyon Kim
The Journal of Organic Chemistry 2015 80 (3), 2001-2005
Journal of the American Chemical Society
Intramolecular Insertions into Unactivated C(sp3)–H Bonds by Oxidatively Generated β-Diketone-α-Gold Carbenes: Synthesis of Cyclopentanones
Youliang Wang, Zhitong Zheng, and Liming Zhang
Journal of the American Chemical Society 2015 137 (16), 5316-5319
Palladium-Catalyzed Intramolecular Insertion of Alkenes into the Carbon–Nitrogen Bond of β-Lactams
Akira Yada, Satoshi Okajima, and Masahiro Murakami
Journal of the American Chemical Society 2015 137 (27), 8708-8711
N-Heterocyclic Carbene Nitric Oxide Radicals
Junbeom Park, Hayoung Song, Youngsuk Kim, Bit Eun, Yonghwi Kim, Dae Young Bae, Sungho Park, Young Min Rhee, Won Jong Kim, Kimoon Kim, and Eunsung Lee
Journal of the American Chemical Society 2015 137 (14), 4642-4645
Organic Letters
Cobalt-Catalyzed C-H Cyanation of (Hetero)arenes and 6-Arylpurines with N-Cyanosuccinimide as a New Cyanating Agent
Amit B. Pawar and Sukbok Chang
Organic Letters 2015 17 (3), 660-663
Enantioselective Synthesis of Bicyclic delta-Lactones via N-Heterocyclic Carbene-Catalyzed Cascade Reaction
Zhi-Qin Liang, Dong-Ling Wang, Han-Ming Zhang, and Song Ye
Organic Letters 2015 17 (20), 5140-5143
DOI: 10.1021/acs.orglett.5b02695
Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone and exo-Methylene Formation
Tsuyoshi Yamamoto, Yuta Tsunematsu, Hiroshi Noguchi, Kinya Hotta, and Kenji Watanabe
Organic Letters 2015 17 (20), 4992-4995
DOI: 10.1021/acs.orglett.5b02435
Organic Process Research & Development
Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions
Bernhard Gutmann, Petteri Elsner, Anne O’Kearney-McMullan, William Goundry, Dominique M. Roberge, and C. Oliver Kappe
Organic Process Research & Development 2015 19 (8), 1062-1067
PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics
Teppei Fujimoto, Fabian Becker, and Tobias Ritter
Organic Process Research & Development 2014 18 (8), 1041-1044
Rapid Electrochemical Deprotection of the Isonicotinyloxycarbonyl Group from Carbonates and Thiocarbonates in a Microfluidic Reactor
Kenta Arai and Thomas Wirth
Organic Process Research & Development 2014 18 (11), 1377-1381
Organometallics
N–H and N–C Bond Formation with an N2-Derived Dihafnium μ-Nitrido Complex
Scott P. Semproni and Paul J. Chirik
Organometallics 2014 33 (14), 3727-3737
Iron Catalysts Containing Amine(imine)diphosphine P-NH-N-P Ligands Catalyze both the Asymmetric Hydrogenation and Asymmetric Transfer Hydrogenation of Ketones
Weiwei Zuo, Sebastian Tauer, Demyan E. Prokopchuk, and Robert H. Morris
Organometallics 2014 33 (20), 5791-5801
Reactivity of an Unsaturated Iridium(III) Phosphoramidate Complex, [Cp*Ir{κ2-N,O}][BArF4]
Marcus W. Drover, Heather C. Johnson, Laurel L. Schafer, Jennifer A. Love, and Andrew S. Weller
Organometallics 2015 34 (15), 3849-3856