Discover the Most-Read Biological Chemistry Articles of October 2018

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in October 2018, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

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Read more of October’s most-read articles: Analytical | Applied | Biological | Materials Science & Engineering | Multidisciplinary | Organic/Inorganic | Physical

DOI: 10.1021/acsbiomaterials.8b01125

Gelatin Hydrogel Combined with Polydopamine Coating To Enhance Tissue Integration of Medical Implants
ACS Biomater. Sci. Eng., 2018, 4 (10), pp 3471–3477
DOI: 10.1021/acsbiomaterials.8b00682

Evaluation of Self-Assembled Glycopeptide Nanofibers Modified with N,N′-Diacetyllactosamine for Selective Galectin-3 Recognition and Inhibition
ACS Biomater. Sci. Eng., 2018, 4 (10), pp 3451–3459
DOI: 10.1021/acsbiomaterials.8b00437


DOI: 10.1021/acscatal.8b02928

Oxygen Evolution Reaction—The Enigma in Water Electrolysis
ACS Catal., 2018, 8 (10), pp 9765–9774
DOI: 10.1021/acscatal.8b02595

Effect of Saturating the Electrolyte with Oxygen on the Activity for the Oxygen Evolution Reaction
Open access through ACS AuthorChoice.
ACS Catal., 2018, 8 (10), pp 9359–9363
DOI: 10.1021/acscatal.8b03014


DOI: 10.1021/acschembio.8b00524

Adversarial Controls for Scientific Machine Learning
ACS Chem. Biol., 2018, 13 (10), pp 2819–2821
DOI: 10.1021/acschembio.8b00665

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach
ACS Chem. Biol., 2018, 13 (10), pp 2862–2867
DOI: 10.1021/acschembio.8b00567


DOI: 10.1021/acschemneuro.8b00528

Psychedelics and Personality
ACS Chem. Neurosci., 2018, 9 (10), pp 2304–2306
DOI: 10.1021/acschemneuro.8b00137

Dark Classics in Chemical Neuroscience: Lysergic Acid Diethylamide (LSD)
This article is part of the “DARK Classics in Chemical Neuroscience” special issue.
ACS Chem. Neurosci., 2018, 9 (10), pp 2331–2343
DOI: 10.1021/acschemneuro.7b00528


DOI: 10.1021/acsinfecdis.8b00160

Noninvasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis
Open access through ACS AuthorChoice
ACS Infect. Dis., 2018, 4 (10), pp 1423–1431
DOI: 10.1021/acsinfecdis.8b00097

Getting Drugs into Gram-Negative Bacteria: Rational Rules for Permeation through General Porins
ACS Infect. Dis., 2018, 4 (10), pp 1487–1498
DOI: 10.1021/acsinfecdis.8b00149


DOI: 10.1021/acsmedchemlett.8b00359

Marine Natural Products in Medicinal Chemistry
ACS Med. Chem. Lett., 2018, 9 (10), pp 959–961
DOI: 10.1021/acsmedchemlett.8b00438

CCR4 Antagonists Inhibit Treg Trafficking into the Tumor Microenvironment
ACS Med. Chem. Lett., 2018, 9 (10), pp 953–955
DOI: 10.1021/acsmedchemlett.8b00416


DOI: 10.1021/acssynbio.8b00164

Discovering Selective Binders for Photoswitchable Proteins Using Phage Display
ACS Synth. Biol., 2018, 7 (10), pp 2355–2364
DOI: 10.1021/acssynbio.8b00242

Establishing a Cell-Free Vibrio natriegens Expression System
ACS Synth. Biol., 2018, 7 (10), pp 2475–2479
DOI: 10.1021/acssynbio.8b00223


DOI: 10.1021/acs.biochem.8b00985

Entry from the Lipid Bilayer: A Possible Pathway for Inhibition of a Peptide G Protein-Coupled Receptor by a Lipophilic Small Molecule
Biochemistry, 2018, 57 (39), pp 5748–5758
DOI: 10.1021/acs.biochem.8b00916

Improved Chemical-Genetic Fluorescent Markers for Live Cell Microscopy
Biochemistry, 2018, 57 (39), pp 5648–5653
DOI: 10.1021/acs.biochem.8b00955


DOI: 10.1021/acs.bioconjchem.8b00511

Selective Uptake Into Drug Resistant Mammalian Cancer by Cell Penetrating Peptide-Mediated Delivery
Bioconjugate Chem., 2018, 29 (10), pp 3273–3284
DOI: 10.1021/acs.bioconjchem.8b00657

Peptide-Directed Photo-Cross-Linking for Site-Specific Conjugation of IgG
Bioconjugate Chem., 2018, 29 (10), pp 3240–3244
DOI: 10.1021/acs.bioconjchem.8b00592


DOI: 10.1021/acs.biomac.8b01093

Robust Polyion Complex Vesicles (PICsomes) under Physiological Conditions Reinforced by Multiple Hydrogen Bond Formation Derived by Guanidinium Groups
Biomacromolecules, 2018, 19 (10), pp 4113–4121
DOI: 10.1021/acs.biomac.8b00556

New Generation of Clickable Nucleic Acids: Synthesis and Active Hybridization with DNA
Biomacromolecules, 2018, 19 (10), pp 4139–4146
DOI: 10.1021/acs.biomac.8b00837


DOI: 10.1021/acs.jafc.8b02355

Breakthroughs in the Health Effects of Plant Food Bioactives: A Perspective on Microbiomics, Nutri(epi)genomics, and Metabolomics
Open access through ACS AuthorChoice
J. Agric. Food Chem., 2018, 66 (41), pp 10686–10692
DOI: 10.1021/acs.jafc.8b04733

Targeting Tumor Metabolism with Plant-Derived Natural Products: Emerging Trends in Cancer Therapy
J. Agric. Food Chem., 2018, 66 (41), pp 10663–10685
DOI: 10.1021/acs.jafc.8b04080


DOI: 10.1021/acs.jctc.8b00634

Tinker 8: Software Tools for Molecular Design
J. Chem. Theory Comput., 2018, 14 (10), pp 5273–5289
DOI: 10.1021/acs.jctc.8b00578

Anomalous Effects of Velocity Rescaling Algorithms: The Flying Ice Cube Effect Revisited
J. Chem. Theory Comput., 2018, 14 (10), pp 5262–5272
DOI: 10.1021/acs.jctc.8b00531


DOI: 10.1021/acs.jmedchem.8b01148

A Dual Inhibition, a Better Solution: Development of a JAK1/TYK2 inhibitor
J. Med. Chem., 2018, 61 (19), pp 8594–8596
DOI: 10.1021/acs.jmedchem.8b00917

Emerging Approaches for the Identification of Protein Targets of Small Molecules – A Practitioners’ Perspective
J. Med. Chem., 2018, 61 (19), pp 8504–8535
DOI: 10.1021/acs.jmedchem.8b00498


DOI: 10.1021/acs.jnatprod.8b00079

Auranthine, a Benzodiazepinone from Penicillium aurantiogriseum: Refined Structure, Absolute Configuration, and Cytotoxicity
J. Nat. Prod., 2018, 81 (10), pp 2177–2186
DOI: 10.1021/acs.jnatprod.7b00845

Structures and Antimutagenic Effects of Onoceranoid-Type Triterpenoids from the Leaves of Lansium domesticum
J. Nat. Prod., 2018, 81 (10), pp 2187–2194
DOI: 10.1021/acs.jnatprod.8b00519


DOI: 10.1021/acs.jpcb.8b06844

Dynamics of Disordered Proteins under Confinement: Memory Effects and Internal Friction
J. Phys. Chem. B, 2018, 122 (39), pp 9049–9060
DOI: 10.1021/acs.jpcb.8b07552

Electronic Resonant Stimulated Raman Scattering Micro-Spectroscopy
This article is part of the “Young Scientists” special issue.
J. Phys. Chem. B, 2018, 122 (39), pp 9218–9224
DOI: 10.1021/acs.jpcb.8b08094


DOI: 10.1021/acs.jpclett.8b02731

Nonadiabatic Excited-State Dynamics with Machine Learning
J. Phys. Chem. Lett., 2018, 9 (19), pp 5660–5663
DOI: 10.1021/acs.jpclett.8b02327

Theory of the Double Layer in Water-in-Salt Electrolytes
J. Phys. Chem. Lett., 2018, 9 (19), pp 5840–5846
DOI: 10.1021/acs.jpclett.8b02298


DOI: 10.1021/acs.jproteome.8b00093

Comparison of an Optimized Ultracentrifugation Method versus Size-Exclusion Chromatography for Isolation of Exosomes from Human Serum
J. Proteome Res., 2018, 17 (10), pp 3599–3605
DOI: 10.1021/acs.jproteome.8b00302

Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq
J. Proteome Res., 2018, 17 (10), pp 3431–3444
DOI: 10.1021/acs.jproteome.8b00269


DOI: 10.1021/acs.molpharmaceut.8b00930

Entangled Conditional Adversarial Autoencoder for de Novo Drug Discovery
Open access through ACS AuthorChoice
Mol. Pharmaceutics, 2018, 15 (10), pp 4398–4405
DOI: 10.1021/acs.molpharmaceut.7b01137

3D Molecular Representations Based on the Wave Transform for Convolutional Neural Networks
Open access through ACS AuthorChoice
Mol. Pharmaceutics, 2018, 15 (10), pp 4378–4385
DOI: 10.1021/acs.molpharmaceut.8b00284

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