We’ve compiled lists of the five most-read biological chemistry articles across the ACS journal portfolio in April 2019, including research, reviews, perspectives, and editorial pieces.

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that appeared in each ACS Publications journal in April 2019, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.
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Read more of April’s most-read articles: Analytical | Applied | Biological | Materials Science & Engineering | Multidisciplinary | Organic/Inorganic | Physical
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3D Printing/Bioprinting Based Tailoring of in Vitro Tissue Models: Recent Advances and Challenges
ACS Appl. Bio Mater., 2019, 2 (4), pp 1385–1405
DOI: 10.1021/acsabm.9b00073
A Chemically Well-Defined, Self-Assembling 3D Substrate for Long-Term Culture of Human Pluripotent Stem Cells
ACS Appl. Bio Mater., 2019, 2 (4), pp 1406–1412
DOI: 10.1021/acsabm.8b00686
Achieving a Stable High Surface Excess of Glucose Oxidase on Pristine Multiwalled Carbon Nanotubes for Glucose Quantification
ACS Appl. Bio Mater., 2019, 2 (4), pp 1740–1750
DOI: 10.1021/acsabm.9b00145
Antimicrobial Hierarchically Porous Graphene Oxide Sponges for Water Treatment
ACS Appl. Bio Mater., 2019, 2 (4), pp 1578–1590
DOI: 10.1021/acsabm.9b00008
Electrophysiological Analysis of Membrane Disruption by Bombinin and Its Isomer Using the Lipid Bilayer System
ACS Appl. Bio Mater., 2019, 2 (4), pp 1542–1548
DOI: 10.1021/acsabm.8b00835
3D Hydrogels Containing Interconnected Microchannels of Subcellular Size for Capturing Human Pathogenic Acanthamoeba Castellanii
Open Access Through ACS AuthorChoice
ACS Biomater. Sci. Eng., 2019, 5 (4), pp 1784–1792
DOI: 10.1021/acsbiomaterials.8b01009
A Biocompatible, Biodegradable, and Functionalizable Copolyester and Its Application in Water-Responsive Shape Memory Scaffold
ACS Biomater. Sci. Eng., 2019, 5 (4), pp 1668–1676
DOI: 10.1021/acsbiomaterials.8b01337
Biomaterials and Bioengineering Approaches for Mitochondria and Nuclear Targeting Drug Delivery
ACS Biomater. Sci. Eng., 2019, 5 (4), pp 1645–1660
DOI: 10.1021/acsbiomaterials.8b01615
Electroceutical Residue-Free Graphene Device for Dopamine Monitoring and Neural Stimulation
ACS Biomater. Sci. Eng., 2019, 5 (4), pp 2013–2020
DOI: 10.1021/acsbiomaterials.8b01488
Engineered Bright Blue- and Red-Emitting Carbon Dots Facilitate Synchronous Imaging and Inhibition of Bacterial and Cancer Cell Progression via 1O2-Mediated DNA Damage under Photoirradiation
ACS Biomater. Sci. Eng., 2019, 5 (4), pp 1987–2000
DOI: 10.1021/acsbiomaterials.9b00149
Introducing the 2019 Early Career Advisory Board of ACS Catalysis
ACS Catal., 2019, 9 (4), pp 3588–3588
DOI: 10.1021/acscatal.9b01141
Metalloporphyrin Catalyzed C–H Amination
ACS Catal., 2019, 9 (4), pp 3604–3617
DOI: 10.1021/acscatal.9b00009
Phantom Reactivity in Organic and Catalytic Reactions as a Consequence of Microscale Destruction and Contamination-Trapping Effects of Magnetic Stir Bars
ACS Catal., 2019, 9 (4), pp 3070–3081
DOI: 10.1021/acscatal.9b00294
Revealing the Synergy between Oxide and Alloy Phases on the Performance of Bimetallic In–Pd Catalysts for CO2 Hydrogenation to Methanol
ACS Catal., 2019, 9 (4), pp 3399–3412
DOI: 10.1021/acscatal.8b04848
Significant Advances in C1 Catalysis: Highly Efficient Catalysts and Catalytic Reactions
ACS Catal., 2019, 9 (4), pp 3026–3053
DOI: 10.1021/acscatal.8b03924
A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments
ACS Chem. Biol., 2019, 14 (4), pp 725–734
DOI: 10.1021/acschembio.9b00008
Chemoproteomic Selectivity Profiling of PIKK and PI3K Kinase Inhibitors
ACS Chem. Biol., 2019, 14 (4), pp 655–664
DOI: 10.1021/acschembio.8b01020
Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase
ACS Chem. Biol., 2019, 14 (4), pp 613–618
DOI: 10.1021/acschembio.9b00211
Directed Evolution of Split APEX2 Peroxidase
Open Access Through ACS Editors’ Choice
ACS Chem. Biol., 2019, 14 (4), pp 619–635
DOI: 10.1021/acschembio.8b00919
Engineered Aminoacyl-tRNA Synthetases with Improved Selectivity toward Noncanonical Amino Acids
ACS Chem. Biol., 2019, 14 (4), pp 603–612
DOI: 10.1021/acschembio.9b00088
Characterization of a Multiple-Scan-Rate Voltammetric Waveform for Real-Time Detection of Met-Enkephalin
Open Access Through ACS Editors’ Choice
This article is part of the Monitoring Molecules in Neuroscience 2018 special issue.
ACS Chem. Neurosci., 2019, 10 (4), pp 2022–2032
DOI: 10.1021/acschemneuro.8b00351
Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases
This article is part of the Monitoring Molecules in Neuroscience 2018 special issue.
ACS Chem. Neurosci., 2019, 10 (4), pp 1867–1871
DOI: 10.1021/acschemneuro.9b00081
Direct, Real-Time Detection of Adenosine Triphosphate Release from Astrocytes in Three-Dimensional Culture Using an Integrated Electrochemical Aptamer-Based Sensor
This article is part of the Monitoring Molecules in Neuroscience 2018 special issue.
ACS Chem. Neurosci., 2019, 10 (4), pp 2070–2079
DOI: 10.1021/acschemneuro.9b00033
Dissecting the Catecholamines: How New Approaches Will Facilitate the Distinction between Noradrenergic and Dopaminergic Systems
This article is part of the Monitoring Molecules in Neuroscience 2018 special issue.
ACS Chem. Neurosci., 2019, 10 (4), pp 1872–1874
DOI: 10.1021/acschemneuro.9b00157
NeuroChat with Professor Steven Townsend
ACS Chem. Neurosci., 2019, 10 (4), pp 2082–2083
DOI: 10.1021/acschemneuro.9b00169
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Evolved Proteins Inhibit Entry of Enfuvirtide-Resistant HIV-1
ACS Infect. Dis., 2019, 5 (4), pp 634–640
DOI: 10.1021/acsinfecdis.8b00362
Investigation of (S)-(−)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase
ACS Infect. Dis., 2019, 5 (4), pp 598–617
DOI: 10.1021/acsinfecdis.8b00345
Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase
ACS Infect. Dis., 2019, 5 (4), pp 570–581
DOI: 10.1021/acsinfecdis.8b00315
Multi-Omics Strategies Uncover Host–Pathogen Interactions
ACS Infect. Dis., 2019, 5 (4), pp 493–505
DOI: 10.1021/acsinfecdis.9b00080
Quantitative Lipid Droplet Proteomics Reveals Mycobacterium tuberculosis Induced Alterations in Macrophage Response to Infection
Open Access Through ACS AuthorChoice
ACS Infect. Dis., 2019, 5 (4), pp 559–569
DOI: 10.1021/acsinfecdis.8b00301
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Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents
Open Access Through ACS AuthorChoice
ACS Med. Chem. Lett., 2019, 10 (4), pp 552–557
DOI: 10.1021/acsmedchemlett.8b00580
Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3
ACS Med. Chem. Lett., 2019, 10 (4), pp 437–443
DOI: 10.1021/acsmedchemlett.8b00484
Cannabinoids from Cannabis sativa L.: A New Tool Based on HPLC–DAD–MS/MS for a Rational Use in Medicinal Chemistry
This article is part of the Highlighting Medicinal Chemistry in Italy special issue.
ACS Med. Chem. Lett., 2019, 10 (4), pp 539–544
DOI: 10.1021/acsmedchemlett.8b00571
Discovery of 1,4-Naphthoquinones as a New Class of Antiproliferative Agents Targeting GPR55
This article is part of the Highlighting Medicinal Chemistry in Italy special issue.
ACS Med. Chem. Lett., 2019, 10 (4), pp 402–406
DOI: 10.1021/acsmedchemlett.8b00333
Drug Design and Synthesis of First in Class PDZ1 Targeting NHERF1 Inhibitors as Anticancer Agents
This article is part of the Highlighting Medicinal Chemistry in Italy special issue.
Open Access Through ACS AuthorChoice
ACS Med. Chem. Lett., 2019, 10 (4), pp 499–503
DOI: 10.1021/acsmedchemlett.8b00532
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A Self-Actuated Cellular Protein Delivery Machine
ACS Synth. Biol., 2019, 8 (4), pp 686–696
DOI: 10.1021/acssynbio.9b00062
A Yeast System for Discovering Optogenetic Inhibitors of Eukaryotic Translation Initiation
ACS Synth. Biol., 2019, 8 (4), pp 744–757
DOI: 10.1021/acssynbio.8b00386
Developing Riboswitch-Mediated Gene Regulatory Controls in Thermophilic Bacteria
ACS Synth. Biol., 2019, 8 (4), pp 633–640
DOI: 10.1021/acssynbio.8b00487
Expanding the Toolbox of Broad Host-Range Transcriptional Terminators for Proteobacteria through Metagenomics
ACS Synth. Biol., 2019, 8 (4), pp 647–654
DOI: 10.1021/acssynbio.8b00507
Knock-In Strategy for Editing Human and Zebrafish Mitochondrial DNA Using Mito-CRISPR/Cas9 System
ACS Synth. Biol., 2019, 8 (4), pp 621–632
DOI: 10.1021/acssynbio.8b00411
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HIV Evades Immune Surveillance by Methylation of Viral RNA
Biochemistry, 2019, 58 (13), pp 1699–1700
DOI: 10.1021/acs.biochem.9b00152
Human Antibody Bispecifics through Phage Display Selection
Biochemistry, 2019, 58 (13), pp 1701–1704
DOI: 10.1021/acs.biochem.9b00037
Learning to Build a β-Carboxysome
Biochemistry, 2019, 58 (16), pp 2091–2092
DOI: 10.1021/acs.biochem.9b00199
Rapid Deorphanization of Human Olfactory Receptors in Yeast
Open Access Through ACS AuthorChoice
Biochemistry, 2019, 58 (16), pp 2160–2166
DOI: 10.1021/acs.biochem.8b01208
Scaring Ribosomes Shiftless
Biochemistry, 2019, 58 (14), pp 1831–1832
DOI: 10.1021/acs.biochem.9b00162
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A Metal-Free DOTA-Conjugated 18F-Labeled Radiotracer: [18F]DOTA-AMBF3-LLP2A for Imaging VLA-4 Over-Expression in Murine Melanoma with Improved Tumor Uptake and Greatly Enhanced Renal Clearance
Bioconjugate Chem., 2019, 30 (4), pp 1210–1219
DOI: 10.1021/acs.bioconjchem.9b00146
Antibody Delivery for Intracellular Targets: Emergent Therapeutic Potential
Bioconjugate Chem., 2019, 30 (4), pp 1028–1041
DOI: 10.1021/acs.bioconjchem.9b00025
Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells
Open Access Through ACS AuthorChoice
Bioconjugate Chem., 2019, 30 (4), pp 1150–1161
DOI: 10.1021/acs.bioconjchem.9b00087
Dual-Bioorthogonal Molecular Tool: “Click-to-Release” and “Double-Click” Reactivity on Small Molecules and Material Surfaces
Bioconjugate Chem., 2019, 30 (4), pp 1140–1149
DOI: 10.1021/acs.bioconjchem.9b00078
Harnessing Exosomes for the Development of Brain Drug Delivery Systems
Bioconjugate Chem., 2019, 30 (4), pp 994–1005
DOI: 10.1021/acs.bioconjchem.9b00085
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Biocompatibility of Resorbable Polymers: A Historical Perspective and Framework for the Future
Open Access Through ACS AuthorChoice
Biomacromolecules, 2019, 20 (4), pp 1465–1477
DOI: 10.1021/acs.biomac.9b00159
Glycopolycation–DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution
Biomacromolecules, 2019, 20 (4), pp 1530–1544
DOI: 10.1021/acs.biomac.8b01704
Inhibiting Ice Recrystallization by Nanocelluloses
Biomacromolecules, 2019, 20 (4), pp 1667–1674
DOI: 10.1021/acs.biomac.9b00027
Poly(N-isopropylacrylamide)-Based Polymer-Inducing Isothermal Hydrophilic-to-Hydrophobic Phase Transition via Detachment of Hydrophilic Acid-Labile Moiety
Biomacromolecules, 2019, 20 (4), pp 1493–1504
DOI: 10.1021/acs.biomac.8b01465
Primary, Secondary, Tertiary and Quaternary Structure Levels in Linear Polysaccharides: From Random Coil, to Single Helix to Supramolecular Assembly
Biomacromolecules, 2019, 20 (4), pp 1731–1739
DOI: 10.1021/acs.biomac.9b00087
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A Dual Cross-Linked Strategy to Construct Moldable Hydrogels with High Stretchability, Good Self-Recovery, and Self-Healing Capability
J. Agric. Food Chem., 2019, 67 (14), pp 3966–3980
DOI: 10.1021/acs.jafc.8b05147
Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model
J. Agric. Food Chem., 2019, 67 (13), pp 3624–3632
DOI: 10.1021/acs.jafc.9b00249
Characterization of the Flavor Properties of Dark Chocolates Produced by a Novel Technological Approach and Comparison with Traditionally Produced Dark Chocolates
J. Agric. Food Chem., 2019, 67 (14), pp 3991–4001
DOI: 10.1021/acs.jafc.8b06800
Expression and Functional Analysis of Two Odorant-Binding Proteins from Bradysia odoriphaga (Diptera: Sciaridae)
J. Agric. Food Chem., 2019, 67 (13), pp 3565–3574
DOI: 10.1021/acs.jafc.9b00568
Fabricating an Acetylcholinesterase Modulated UCNPs-Cu2+ Fluorescence Biosensor for Ultrasensitive Detection of Organophosphorus Pesticides-Diazinon in Food
J. Agric. Food Chem., 2019, 67 (14), pp 4071–4079
DOI: 10.1021/acs.jafc.8b07201
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Automated Multiscale Approach To Predict Self-Diffusion from a Potential Energy Field
Open Access Through ACS AuthorChoice
J. Chem. Theory Comput., 2019, 15 (4), pp 2127–2141
DOI: 10.1021/acs.jctc.8b01255
Enhanced Sampling of Transition States
J. Chem. Theory Comput., 2019, 15 (4), pp 2454–2459
DOI: 10.1021/acs.jctc.8b01283
First Principle Prediction of Intramolecular Singlet Fission and Triplet Triplet Annihilation Rates
J. Chem. Theory Comput., 2019, 15 (4), pp 2246–2253
DOI: 10.1021/acs.jctc.8b01185
Learning from Failure: Predicting Electronic Structure Calculation Outcomes with Machine Learning Models
J. Chem. Theory Comput., 2019, 15 (4), pp 2331–2345
DOI: 10.1021/acs.jctc.9b00057
Machine-Learned Fragment-Based Energies for Crystal Structure Prediction
Open Access Through ACS AuthorChoice
J. Chem. Theory Comput., 2019, 15 (4), pp 2743–2758
DOI: 10.1021/acs.jctc.9b00038
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Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor
J. Med. Chem., 2019, 62 (7), pp 3254–3267
DOI: 10.1021/acs.jmedchem.8b01719
Development of Covalent Ligands for G Protein-Coupled Receptors: A Case for the Human Adenosine A3 Receptor
Open Access Through ACS AuthorChoice
J. Med. Chem., 2019, 62 (7), pp 3539–3552
DOI: 10.1021/acs.jmedchem.8b02026
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinase (BTK)
J. Med. Chem., 2019, 62 (7), pp 3228–3250
DOI: 10.1021/acs.jmedchem.9b00167
Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors
J. Med. Chem., 2019, 62 (7), pp 3407–3427
DOI: 10.1021/acs.jmedchem.8b01888
FragLites—Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation
J. Med. Chem., 2019, 62 (7), pp 3741–3752
DOI: 10.1021/acs.jmedchem.9b00304
Acylated Lignans Isolated from Brachanthemum gobicum and Their Trypanocidal Activity
J. Nat. Prod., 2019, 82 (4), pp 774–784
DOI: 10.1021/acs.jnatprod.8b00670
Anti-inflammatory Lathyrane Diterpenoids from Euphorbia lathyris
J. Nat. Prod., 2019, 82 (4), pp 756–764
DOI: 10.1021/acs.jnatprod.8b00600
Camporidines A and B: Antimetastatic and Anti-inflammatory Polyketide Alkaloids from a Gut Bacterium of Camponotus kiusiuensis
J. Nat. Prod., 2019, 82 (4), pp 903–910
DOI: 10.1021/acs.jnatprod.8b01000
Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes
J. Nat. Prod., 2019, 82 (4), pp 937–946
DOI: 10.1021/acs.jnatprod.8b01028
Inducing Secondary Metabolite Production by Co-culture of the Endophytic Fungus Phoma sp. and the Symbiotic Fungus Armillaria sp.
J. Nat. Prod., 2019, 82 (4), pp 1009–1013
DOI: 10.1021/acs.jnatprod.8b00685
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Benchmarking Hybrid Atomistic/Coarse-Grained Schemes for Proteins with an Atomistic Water Layer
J. Phys. Chem. B, 2019, 123 (14), pp 3033–3042
DOI: 10.1021/acs.jpcb.8b12149
Combinatorial Control through Allostery
J. Phys. Chem. B, 2019, 123 (13), pp 2792–2800
DOI: 10.1021/acs.jpcb.8b12517
Effect of Ions on Water Dynamics in Dilute and Concentrated Aqueous Salt Solutions
Published as part of The Journal of Physical Chemistry virtual special issue Young Scientists.
J. Phys. Chem. B, 2019, 123 (15), pp 3312–3324
DOI: 10.1021/acs.jpcb.9b01053
High-Resolution 17O NMR Spectroscopy of Structural Water
J. Phys. Chem. B, 2019, 123 (14), pp 3061–3067
DOI: 10.1021/acs.jpcb.9b02277
Machine Learning Prediction of DNA Charge Transport
Published as part of The Journal of Physical Chemistry virtual special issue Young Scientists.
J. Phys. Chem. B, 2019, 123 (13), pp 2801–2811
DOI: 10.1021/acs.jpcb.8b12557
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Complete Phase Diagram for Liquid–Liquid Phase Separation of Intrinsically Disordered Proteins
J. Phys. Chem. Lett., 2019, 10 (8), pp 1644–1652
DOI: 10.1021/acs.jpclett.9b00099
Doping Mn(II) in All-Inorganic Ruddlesden–Popper Phase of Tetragonal Cs2PbCl2I2 Perovskite Nanoplatelets
J. Phys. Chem. Lett., 2019, 10 (8), pp 1954–1959
DOI: 10.1021/acs.jpclett.9b00738
DORI Reveals the Influence of Noncovalent Interactions on Covalent Bonding Patterns in Molecular Crystals Under Pressure
Open Access Through ACS AuthorChoice
J. Phys. Chem. Lett., 2019, 10 (7), pp 1482–1488
DOI: 10.1021/acs.jpclett.9b00220
Importance of the Force Field Choice in Capturing Functionally Relevant Dynamics in the von Willebrand Factor
Open Access Through ACS AuthorChoice
J. Phys. Chem. Lett., 2019, 10 (8), pp 1928–1934
DOI: 10.1021/acs.jpclett.9b00517
Intermolecular Interaction-Induced Thermally Activated Delayed Fluorescence Based on a Thiochromone Derivative
J. Phys. Chem. Lett., 2019, 10 (8), pp 1888–1893
DOI: 10.1021/acs.jpclett.9b00512
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A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation
Open Access Through ACS AuthorChoice
J. Proteome Res., 2019, 18 (4), pp 1607–1622
DOI: 10.1021/acs.jproteome.8b00895
An Improved Method for Measuring Absolute Metabolite Concentrations in Small Biofluid or Tissue Samples
Open Access Through ACS AuthorChoice
J. Proteome Res., 2019, 18 (4), pp 1503–1512
DOI: 10.1021/acs.jproteome.8b00773
Coacervation of Lipid Bilayer in Natural Cell Membranes for Extraction, Fractionation, and Enrichment of Proteins in Proteomics Studies
J. Proteome Res., 2019, 18 (4), pp 1595–1606
DOI: 10.1021/acs.jproteome.8b00857
Development of a Sensitive, Scalable Method for Spatial, Cell-Type-Resolved Proteomics of the Human Brain
Open Access Through ACS AuthorChoice
J. Proteome Res., 2019, 18 (4), pp 1787–1795
DOI: 10.1021/acs.jproteome.8b00981
Evaluating Chromatographic Approaches for the Quantitative Analysis of a Human Proteome on Orbitrap-Based Mass Spectrometry Systems
J. Proteome Res., 2019, 18 (4), pp 1857–1869
DOI: 10.1021/acs.jproteome.9b00036
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Computational Techniques for Predicting Mechanical Properties of Organic Crystals: A Systematic Evaluation
Mol. Pharmaceutics, 2019, 16 (4), pp 1732–1741
DOI: 10.1021/acs.molpharmaceut.9b00082
Correction to “Polymer-Mediated Drug Supersaturation Controlled by Drug–Polymer Interactions Persisting in an Aqueous Environment”
Mol. Pharmaceutics, 2019, 16 (4), pp 1787–1787
DOI: 10.1021/acs.molpharmaceut.9b00229
Correction to “Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect
Mol. Pharmaceutics, 2019, 16 (4), pp 1788–1788
DOI: 10.1021/acs.molpharmaceut.9b00299
Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria
Open Access Through ACS AuthorChoice
Mol. Pharmaceutics, 2019, 16 (4), pp 1658–1668
DOI: 10.1021/acs.molpharmaceut.8b01333
Microstructure Formation for Improved Dissolution Performance of Lopinavir Amorphous Solid Dispersions
Mol. Pharmaceutics, 2019, 16 (4), pp 1751–1765
DOI: 10.1021/acs.molpharmaceut.9b00117
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