Discover the Most-Read Chemistry Articles of 2021 - ACS Axial | ACS Publications
Search
Close

Discover the Most-Read Chemistry Articles of 2021

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles that were published in each ACS Publications journal during 2021, including papers, reviews, perspectives, and editorial pieces. These lists were not chosen by the journals’ editors and should not be taken as a “best of” list, but as another perspective on what newly published research attracted the most attention in a particular month.

Click on your favorite journal below to see their most-read articles that were published in all of 2021.

Sign up to get this list in your inbox every month.

Browse 2021’s Monthly Most-Read Article Lists


Accounts of Chemical Research
***
Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer
DOI: 10.1021/acs.accounts.0c00591

Data-Driven Strategies for Accelerated Materials Design
DOI: 10.1021/acs.accounts.0c00785

Assembly-Line Catalysis in Bifunctional Terpene Synthases
DOI: 10.1021/acs.accounts.1c00296

Radical Carboxylative Cyclizations and Carboxylations with CO2
DOI: 10.1021/acs.accounts.1c00135

Ideality in Context: Motivations for Total Synthesis
DOI: 10.1021/acs.accounts.0c00821


Accounts of Materials Research
***
Research Material Foundation for Future 5G Technology
DOI: 10.1021/accountsmr.0c00087

Research Self-Powered Wearable Biosensors
DOI: 10.1021/accountsmr.1c00002

In Situ Wood Delignification toward Sustainable Applications
DOI: 10.1021/accountsmr.1c00075

Liquid Metal Transformable Machines
DOI: 10.1021/accountsmr.1c00182

Nanozymes Inspired by Natural Enzymes
DOI: 10.1021/accountsmr.1c00074


ACS Agricultural Science & Technology
***
Design, Synthesis, Antivirus Activity, and SARs of Phenanthroquinolizidine Alkaloid Derivatives
DOI: 10.1021/acsagscitech.1c00032

Will the Chemical Contaminants in Agricultural Soil Affect the Ecotoxicity of Microplastics?
DOI: 10.1021/acsagscitech.0c00005

A New Era in Agricultural Science Research Where Innovation in Sustainability Takes Center Stage
DOI: 10.1021/acsagscitech.0c00060

Nickel Influences Urease Activity and Calcium Distribution in Tomato Fruits
DOI: 10.1021/acsagscitech.0c00003

Nanocarrier-Mediated Delivery of miRNA, RNAi, and CRISPR-Cas for Plant Protection: Current Trends and Future Directions
DOI: 10.1021/acsagscitech.1c00146


ACS Applied Bio Materials
***
Osteogenic Potential of Additively Manufactured TiTa Alloys
DOI: 10.1021/acsabm.0c01450

Screening of Fv Antibodies with Specific Binding Activities to Monosodium Urate and Calcium Pyrophosphate Dihydrate Crystals for the Diagnosis of Gout and Pseudogout
DOI: 10.1021/acsabm.0c01680

Catalyst-Free Mechanochemical Recycling of Biobased Epoxy with Cellulose Nanocrystals
DOI: 10.1021/acsabm.0c01670

Study on the Functionalization and Signaling Efficiency of the Hybridization Chain Reaction Using Traditional and Single Molecular Characterizations
DOI: 10.1021/acsabm.1c00136

PtNPt/MWCNT-PEDOT:PSS-Modified Microelectrode Arrays for the Synchronous Dopamine and Neural Spike Detection in Rat Models of Sleep Deprivation
DOI: 10.1021/acsabm.1c00172


ACS Applied Electronic Materials
***
High Quantum Yield Gd4.67Si3O13:Eu3+ Red-Emitting Phosphor for Tunable White Light-Emitting Devices Driven by UV or Blue LED
DOI: 10.1021/acsaelm.1c00012

Record-High Responsivity and Detectivity of a Flexible Deep-Ultraviolet Photodetector Based on Solid State-Assisted Synthesized hBN Nanosheets
DOI: 10.1021/acsaelm.0c01021

Extended Compositional Range for the Synthesis of SWIR and LWIR Ge1–ySny Alloys and Device Structures via CVD of SnH4 and Ge3H8
DOI: 10.1021/acsaelm.1c00424

High-Quality Sputtered BiFeO3 for Ultrathin Epitaxial Films
DOI: 10.1021/acsaelm.1c00688

Impact of La Concentration on Ferroelectricity of La-Doped HfO2 Epitaxial Thin Films
DOI: 10.1021/acsaelm.1c00672


ACS Applied Energy Materials
***
Enhanced Performance of the Sb2Se3 Thin-Film Solar Cell by Organic Molecule-Induced Crystallization and Suppression of the Interface Recombination
DOI: 10.1021/acsaem.1c00640

Enhanced Thermoelectric Performance in n-Type Bi2O2Se by an Exquisite Grain Boundary Engineering Approach
DOI: 10.1021/acsaem.1c02219

Effect of Pt and Ionomer Distribution on Polymer Electrolyte Fuel Cell Performance and Durability
DOI: 10.1021/acsaem.0c02841

Room-Temperature Solid-State Lithium-Ion Battery Using a LiBH4–MgO Composite Electrolyte
DOI: 10.1021/acsaem.0c02525

Garnet-Poly( -caprolactone-co-trimethylene carbonate) Polymer-in-Ceramic Composite Electrolyte for All-Solid-State Lithium-Ion Batteries
DOI: 10.1021/acsaem.0c03098


ACS Applied Materials & Interfaces
***
Smart Protein-Based Biolasers: An Alternative Way to Protein Conformation Detection
DOI: 10.1021/acsami.0c22270

Cerium-Based Metal–Organic Framework Nanocrystals Interconnected by Carbon Nanotubes for Boosting Electrochemical Capacitor Performance
DOI: 10.1021/acsami.1c02038

Fabrication of 3D-Printed Ceramic Structures for Portable Solar Desalination Devices
DOI: 10.1021/acsami.1c04209

Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds
DOI: 10.1021/acsami.1c01754

Shaping of a Metal–Organic Framework–Polymer Composite and Its CO2 Adsorption Performances from Humid Indoor Air
DOI: 10.1021/acsami.1c06089


ACS Applied Nano Materials
***
Large-Scale Preparation of Durable VO2 Nanocomposite Coatings
DOI: 10.1021/acsanm.1c00387

Epidermal Graphene Sensors and Machine Learning for Estimating Swallowed Volume
DOI: 10.1021/acsanm.1c01378

Aromaphilicity Index of Amino Acids: Molecular Dynamics Simulations of the Protein Binding Affinity for Carbon Nanomaterials
DOI: 10.1021/acsanm.0c03047

One-Step Hydrothermal Synthesis of Phase-Engineered MoS2/MoO3 Electrocatalysts for Hydrogen Evolution Reaction
DOI: 10.1021/acsanm.0c03274

Engineering Shape Anisotropy of Fe3O4– -Fe2O3 Hollow Nanoparticles for Magnetic Hyperthermia
DOI: 10.1021/acsanm.1c00311


ACS Applied Polymer Materials
***
Polymer Materials for Respiratory Protection: Processing, End Use, and Testing Methods
DOI: 10.1021/acsapm.0c01151

Three-Dimensional Fine Structure of Nanometer-Scale Nafion Thin Films
DOI: 10.1021/acsapm.0c01318

Recent Trends in Advanced Polymer Materials in Agriculture Related Applications
DOI: 10.1021/acsapm.0c00982

Three-Dimensional Printable Enzymatically Active Plastics
DOI: 10.1021/acsapm.1c00845

Recycling Thermoset Epoxy Resin Using Alkyl-Methyl-Imidazolium Ionic Liquids as Green Solvents
DOI: 10.1021/acsapm.1c00896


ACS Bio & Med Chem Au
***
Stable Gold-Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens
DOI: 10.1021/acsbiomedchemau.1c00021

Iso- -acids in Nonalcoholic and Alcoholic Beer Stimulate Growth of Neuron-like SH-SY5Y Cells and Neuroepithelial Stem Cells
Open Access
DOI: 10.1021/acsbiomedchemau.1c00017

Funding Mandates and the Launch of Nine Fully Open Access ACS Au Journals
DOI: 10.1021/acsbiomedchemau.1c00004

Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining
DOI: 10.1021/acsbiomedchemau.1c00016

Discovery of “Molecular Switches” within a Series of mGlu5 Allosteric Ligands Driven by a “Magic Methyl” Effect Affording Both PAMs and NAMs with In Vivo Activity, Derived from an M1 PAM Chemotype
DOI: 10.1021/acsbiomedchemau.1c00024


ACS Biomaterials Science & Engineering
***
Antimicrobial Peptide-Functionalized Mesoporous Hydrogels
DOI: 10.1021/acsbiomaterials.1c00029

FleXert: A Soft, Actuatable Multiwell Plate Insert for Cell Culture under Stretch
DOI: 10.1021/acsbiomaterials.0c01448

Cationic Lignin-Based Hyperbranched Polymers to Circumvent Drug Resistance in Pseudomonas Keratitis
DOI: 10.1021/acsbiomaterials.1c00856

Engineering Hydrogel Adhesion for Biomedical Applications via Chemical Design of the Junction
DOI: 10.1021/acsbiomaterials.0c01677

Experimental Evidence for the Optimal Design of a High-Performing Cloth Mask
DOI: 10.1021/acsbiomaterials.1c00368


ACS Catalysis
***
Elucidating the Facet-Dependent Selectivity for CO2 Electroreduction to Ethanol of Cu–Ag Tandem Catalysts
DOI: 10.1021/acscatal.1c00420

CuFeO2–Water Interface under Illumination: Structural, Electronic, and Catalytic Implications for the Hydrogen Evolution Reaction
DOI: 10.1021/acscatal.0c05066

Harnessing the Substrate Promiscuity of Dioxygenase AsqJ and Developing Efficient Chemoenzymatic Synthesis for Quinolones
DOI: 10.1021/acscatal.1c01150

Multiscale Simulations of SARS-CoV-2 3CL Protease Inhibition with Aldehyde Derivatives. Role of Protein and Inhibitor Conformational Changes in the Reaction Mechanism
DOI: 10.1021/acscatal.0c05522

Promiscuous Dehalogenase Activity of the Epoxide Hydrolase CorEH from Corynebacterium sp. C12
DOI: 10.1021/acscatal.1c00851


ACS Central Science
***
A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development
DOI: 10.1021/acscentsci.1c00120

A Single Immunization with Spike-Functionalized Ferritin Vaccines Elicits Neutralizing Antibody Responses against SARS-CoV-2 in Mice
DOI: 10.1021/acscentsci.0c01405

Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines
DOI: 10.1021/acscentsci.1c00197

Native-like SARS-CoV-2 Spike Glycoprotein Expressed by ChAdOx1 nCoV-19/AZD1222 Vaccine
DOI: 10.1021/acscentsci.1c00080

C–H Activation: Toward Sustainability and Applications
DOI: 10.1021/acscentsci.0c01413


ACS Chemical Biology
***
The Promise and Peril of Chemical Probe Negative Controls
DOI: 10.1021/acschembio.1c00036

Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)
DOI: 10.1021/acschembio.1c00693

High-Throughput miRFluR Platform Identifies miRNA Regulating B3GLCT That Predict Peters’ Plus Syndrome Phenotype, Supporting the miRNA Proxy Hypothesis
DOI: 10.1021/acschembio.1c00247

The Promise and Peril of Chemical Probe Negative Controls
DOI: 10.1021/acschembio.1c00036

A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells
DOI: 10.1021/acschembio.0c00875


ACS Chemical Health & Safety
***
Safety Cloth Face Masks Containing Silver: Evaluating the Status
DOI: 10.1021/acs.chas.1c00005

Safety Fall 2020 Proceedings of the Cannabis Chemistry Subdivision
DOI: 10.1021/acs.chas.0c00119

Safety Increased Use of Disinfectants During the COVID-19 Pandemic and Its Potential Impacts on Health and Safety
DOI: 10.1021/acs.chas.1c00026

Safety Improving the Quality of Literature Reviews in Chemistry: Tools and Techniques
DOI: 10.1021/acs.chas.1c00046

Safety The Ten Most Common Laboratory Safety Issues
DOI: 10.1021/acs.chas.1c00063


ACS Chemical Neuroscience
***
Persistent Brainstem Dysfunction in Long-COVID: A Hypothesis
DOI: 10.1021/acschemneuro.0c00793

Interactions between SARS-CoV-2 N-Protein and -Synuclein Accelerate Amyloid Formation
DOI: 10.1021/acschemneuro.1c00666

Genetic Probe for Visualizing Glutamatergic Synapses and Vesicles by 3D Electron Microscopy
DOI: 10.1021/acschemneuro.0c00643

Mechanism of Anosmia Caused by Symptoms of COVID-19 and Emerging Treatments
DOI: 10.1021/acschemneuro.1c00477

In Vitro and In Vivo Investigation of S1PR1 Expression in the Central Nervous System Using [3H]CS1P1 and [11C]CS1P1
DOI: 10.1021/acschemneuro.1c00492


ACS Earth and Space Chemistry
***
Purification of Disc-Shaped Diatoms from the Southern Ocean Sediment by a Cell Sorter to Obtain an Accurate Oxygen Isotope Record
DOI: 10.1021/acsearthspacechem.1c00201

Sensitive Drone Mapping of Methane Emissions without the Need for Supplementary Ground-Based Measurements
DOI: 10.1021/acsearthspacechem.1c00106

Purification of Disc-Shaped Diatoms from the Southern Ocean Sediment by a Cell Sorter to Obtain an Accurate Oxygen Isotope Record
DOI: 10.1021/acsearthspacechem.1c00201

Aging of Atmospheric Brown Carbon Aerosol
DOI: 10.1021/acsearthspacechem.0c00346

Estimation of Skin and Ocular Damage Avoided in the United States through Implementation of the Montreal Protocol on Substances that Deplete the Ozone Layer
DOI: 10.1021/acsearthspacechem.1c00183


ACS Energy Letters
***
Opportunities and Challenges of Lithium Ion Batteries in Automotive Applications
DOI: 10.1021/acsenergylett.0c02584

Five Key Attributes of an Effective Title
DOI: 10.1021/acsenergylett.1c00755

Is There Anything Better than Pt for HER?
DOI: 10.1021/acsenergylett.1c00246

Enhanced Performance and Stability of 3D/2D Tin Perovskite Solar Cells Fabricated with a Sequential Solution Deposition
DOI: 10.1021/acsenergylett.0c02305

Challenges for and Pathways toward Li-Metal-Based All-Solid-State Batteries
DOI: 10.1021/acsenergylett.1c00445


ACS Engineering Au
***
Postcombustion CO2 Capture: A Comparative Techno-Economic Assessment of Three Technologies Using a Solvent, an Adsorbent, and a Membrane
DOI: 10.1021/acsengineeringau.1c00002

Durable Polylactic Acid (PLA)-Based Sustainable Engineered Blends and Biocomposites: Recent Developments, Challenges, and Opportunities
DOI: 10.1021/acsengineeringau.1c00011

Postcombustion CO2 Capture: A Comparative Techno-Economic Assessment of Three Technologies Using a Solvent, an Adsorbent, and a Membrane
DOI: 10.1021/acsengineeringau.1c00002

Modeling Growth Kinetics of Methane Hydrate in Stirred Tank Batch Reactors
DOI: 10.1021/acsengineeringau.1c00012

Funding Mandates and the Launch of Nine Fully Open Access ACS Au Journals
DOI: 10.1021/acsengineeringau.1c00001


ACS Environmental Au
***
Measurements and Simulations of Aerosol Released while Singing and Playing Wind Instruments
DOI: 10.1021/acsenvironau.1c00007

The Human Impact on All Soil-Forming Factors during the Anthropocene
DOI: 10.1021/acsenvironau.1c00010

Impacts of COVID-19 Outbreak on the Municipal Solid Waste Management: Now and beyond the Pandemic
DOI: 10.1021/acsenvironau.1c00005

Microplastics through the Lens of Colloid Science
DOI: 10.1021/acsenvironau.1c00016

Wastewater-Based Epidemiology for Community Monitoring of SARS-CoV-2: Progress and Challenges
DOI: 10.1021/acsenvironau.1c00015


ACS Environmental Science & Technology Water
***
Methodological Advances to Study Contaminant Biotransformation: New Prospects for Understanding and Reducing Environmental Persistence?
DOI: 10.1021/acsestwater.1c00025

Electrochemical Biosensors for Detection of Pesticides and Heavy Metal Toxicants in Water: Recent Trends and Progress
DOI: 10.1021/acsestwater.0c00125

Welcome to ACS ES&T Water: Vision and Inspiration
DOI: 10.1021/acsestwater.0c00298

The Price of Really Clean Water: Combining Nanofiltration with Granular Activated Carbon and Anion Exchange Resins for the Removal of Per- And Polyfluoralkyl Substances (PFASs) in Drinking Water Production
DOI: 10.1021/acsestwater.0c00141

Urban Stormwater Runoff: A Major Pathway for Anthropogenic Particles, Black Rubbery Fragments, and Other Types of Microplastics to Urban Receiving Waters
DOI: 10.1021/acsestwater.1c00017


ACS ES&T Engineering
***
Effect of Process Variables on Food Waste Valorization via Hydrothermal Liquefaction
DOI: 10.1021/acsestengg.0c00115

Electrified Membranes for Water Treatment Applications
DOI: 10.1021/acsestengg.1c00015

Screening and Optimization of Microalgae Biomass and Plastic Material Coprocessing by Hydrothermal Liquefaction
DOI: 10.1021/acsestengg.1c00261

Dynamically Controlled Environment Agriculture: Integrating Machine Learning and Mechanistic and Physiological Models for Sustainable Food Cultivation
DOI: 10.1021/acsestengg.1c00269

Nano-enhanced Bioremediation for Oil Spills: A Review
DOI: 10.1021/acsestengg.0c00217


ACS Food Science & Technology
***
Sterol Ferulate Rich Wheat Bran Oil Concentrate Prevents Liver Damage in MAFLD Mouse Model by Modulating FAS and PCSK9
DOI: 10.1021/acsfoodscitech.0c00156

Isolation and Gelling Properties of Duckweed Protein Concentrate
DOI: 10.1021/acsfoodscitech.1c00009

Production of Endotoxin-Free Microbial Biomass for Food Applications by Gas Fermentation of Gram-Positive H2-Oxidizing Bacteria
DOI: 10.1021/acsfoodscitech.0c00129

Recent Advances in Intelligent Food Packaging Applications Using Natural Food Colorants
DOI: 10.1021/acsfoodscitech.0c00039

Diospyros digyna (black sapote), an Undervalued Fruit: A Review
DOI: 10.1021/acsfoodscitech.0c00103


ACS Infectious Diseases
***
Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin
DOI: 10.1021/acsinfecdis.0c00701

Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions
DOI: 10.1021/acsinfecdis.0c00788

Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum
DOI: 10.1021/acsinfecdis.1c00047

The CARB-X Portfolio of Nontraditional Antibacterial Products
DOI: 10.1021/acsinfecdis.1c00331

In Vivo Activity of Repurposed Amodiaquine as a Host-Targeting Therapy for the Treatment of Anthrax
DOI: 10.1021/acsinfecdis.1c00190


ACS Macro Letters
***
Synthesis and Characterization of Redox-Responsive Disulfide Cross-Linked Polymer Particles for Energy Storage Applications
DOI: 10.1021/acsmacrolett.1c00682

Entrepreneurship in Polymer Chemistry
DOI: 10.1021/acsmacrolett.1c00303

Three-Dimensional Printable Gelatin Hydrogels Incorporating Graphene Oxide to Enable Spontaneous Myogenic Differentiation
DOI: 10.1021/acsmacrolett.1c00563

Light-Enabled Reversible Shape Transformation of Block Copolymer Particles
DOI: 10.1021/acsmacrolett.1c00356

Closed-Loop Recycling of Both Resin and Fiber from High-Performance Thermoset Epoxy/Carbon Fiber Composites
DOI: 10.1021/acsmacrolett.1c00437


ACS Materials Au
***
Transition Metal Chalcogenides as a Versatile and Tunable Platform for Catalytic CO2 and N2 Electroreduction
DOI: 10.1021/acsmaterialsau.1c00006

Transition Metal Chalcogenides as a Versatile and Tunable Platform for Catalytic CO2 and N2 Electroreduction
Open Access
DOI: 10.1021/acsmaterialsau.1c00006

Structure–Processing–Property Relationships of 3D Printed Porous Polymeric Materials
DOI: 10.1021/acsmaterialsau.1c00017

Roles of Graphene Oxide in Heterogeneous Photocatalysis
DOI: 10.1021/acsmaterialsau.1c00022

(NH4)2AgX3 (X = Br, I): 1D Silver Halides with Broadband White Light Emission and Improved Stability
DOI: 10.1021/acsmaterialsau.1c00009


ACS Materials Letters
***
Two-Dimensional Materials for Perovskite Solar Cells with Enhanced Efficiency and Stability
DOI: 10.1021/acsmaterialslett.1c00327

Principles of Molecular Machines at the Single-Molecule Scale
DOI: 10.1021/acsmaterialslett.1c00366

CsMnBr3: Lead-Free Nanocrystals with High Photoluminescence Quantum Yield and Picosecond Radiative Lifetime
DOI: 10.1021/acsmaterialslett.1c00663

Mechanochemical Synthesis and Structure of Lithium Tetrahaloaluminates, LiAlX4 (X = Cl, Br, I): A Family of Li-Ion Conducting Ternary Halides
DOI: 10.1021/acsmaterialslett.1c00055

Perspective on High-Rate Alkaline Water Splitting
DOI: 10.1021/acsmaterialslett.0c00536


ACS Measurement Science Au
***
A Workflow to Perform Targeted Metabolomics at the Untargeted Scale on a Triple Quadrupole Mass Spectrometer
DOI: 10.1021/acsmeasuresciau.1c00007

In Situ X-ray Absorption Spectroscopy and Droplet-Based Microfluidics: An Analysis of Calcium Carbonate Precipitation
DOI: 10.1021/acsmeasuresciau.1c00005

Artificial Synapse: Spatiotemporal Heterogeneities in Dopamine Electrochemistry at a Carbon Fiber Ultramicroelectrode
DOI: 10.1021/acsmeasuresciau.1c00006

Novel, User-Friendly Experimental and Analysis Strategies for Fast Voltammetry: 1. The Analysis Kid for FSCV
DOI: 10.1021/acsmeasuresciau.1c00003

Dual “Static and Dynamic” Fluorescence Quenching Mechanisms Based Detection of TNT via a Cationic Conjugated Polymer
DOI: 10.1021/acsmeasuresciau.1c00023


ACS Medicinal Chemistry Letters
***
Molecular Biology Clues Portray SARS-CoV-2 as a Gain-of-Function Laboratory Manipulation of Bat CoV RaTG13
DOI: 10.1021/acsmedchemlett.1c00274

Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction
DOI: 10.1021/acsmedchemlett.1c00074

Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology

DOI: 10.1021/acsmedchemlett.1c00195

Targeting the KRAS G12D Mutant as Potential Therapy in Cancer
DOI: 10.1021/acsmedchemlett.1c00390

Computer Prediction of pKa Values in Small Molecules and Proteins
DOI: 10.1021/acsmedchemlett.1c00435


ACS Nano
***
State of the Art and Prospects for Halide Perovskite Nanocrystals
DOI: 10.1021/acsnano.0c08903

Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement
DOI: 10.1021/acsnano.1c04996

X-ray-Based Techniques to Study the Nano–Bio Interface
DOI: 10.1021/acsnano.0c09563

Applications of Few-Layer Nb2C MXene: Narrow-Band Photodetectors and Femtosecond Mode-Locked Fiber Lasers
DOI: 10.1021/acsnano.0c07608

Cell to Cell Signaling through Light in Artificial Cell Communities: Glowing Predator Lures Prey
DOI: 10.1021/acsnano.1c01600


ACS Nanoscience Au
***
Luciferase-Based Biosensors in the Era of the COVID-19 Pandemic
DOI: 10.1021/acsnanoscienceau.1c00009

Ligand Ratio Plays a Critical Role in the Design of Optimal Multifunctional Gold Nanoclusters for Targeted Gastric Cancer Therapy
DOI: 10.1021/acsnanoscienceau.1c00008

Funding Mandates and the Launch of Nine Fully Open Access ACS Au Journals
DOI: 10.1021/acsnanoscienceau.1c00004

Topogami: Topologically Linked DNA Origami
DOI: 10.1021/acsnanoscienceau.1c00027

Design of Over-1000 nm Near-Infrared Fluorescent Polymeric Micellar Nanoparticles by Matching the Solubility Parameter of the Core Polymer and Dye
DOI: 10.1021/acsnanoscienceau.1c00010


ACS Omega
***
Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography
DOI: 10.1021/acsomega.1c04196

Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
DOI: 10.1021/acsomega.1c00772

Preanalytical Issues and Cycle Threshold Values in SARS-CoV-2 Real-Time RT-PCR Testing: Should Test Results Include These?
DOI: 10.1021/acsomega.1c00166

How Many CO2 Bubbles in a Glass of Beer?
DOI: 10.1021/acsomega.1c00256

Tuning the Oxygen Content of Reduced Graphene Oxide and Effects on Its Properties
DOI: 10.1021/acsomega.0c05578


ACS Organic & Inorganic Au
***
Synthesis and Physicochemical Properties of 2-SF5-(Aza)Indoles, a New Family of SF5 Heterocycles
DOI: 10.1021/acsorginorgau.1c00010

Electrochemical TEMPO-Catalyzed Oxidative Ugi-Type Reaction

DOI: 10.1021/acsorginorgau.1c00003

Enabling Cyclization Strategies through Carbonyl-Ylide-Mediated Synthesis of Malonate Enol Ethers

DOI: 10.1021/acsorginorgau.1c00006

Visible-Light-Driven C–S Bond Formation Based on Electron Donor–Acceptor Excitation and Hydrogen Atom Transfer Combined System

DOI: 10.1021/acsorginorgau.1c00007

Turn-On Fluorescent Probe Based on a Dansyl Triarginine Peptide for Ganglioside Imaging

DOI: 10.1021/acsorginorgau.1c00013


ACS Pharmacology & Translational Science
***
Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 Replication by Hypertonic Saline Solution in Lung and Kidney Epithelial Cells
DOI: 10.1021/acsptsci.1c00080

Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19
DOI: 10.1021/acsptsci.0c00221

Ethical Concerns about Psilocybin Intellectual Property
DOI: 10.1021/acsptsci.0c00171

Predicting Reactions to Psychedelic Drugs: A Systematic Review of States and Traits Related to Acute Drug Effects
DOI: 10.1021/acsptsci.1c00014

SARS-CoV-2, Hypoxia, and Calcium Signaling: The Consequences and Therapeutic Options
DOI: 10.1021/acsptsci.0c00219


ACS Photonics
***
Violating Kirchhoff’s Law of Thermal Radiation in Semitransparent Structures

DOI: 10.1021/acsphotonics.1c00612

Nanoscale Mapping of Recombinant Viral Proteins: From Cells to Virus-Like Particles
DOI: 10.1021/acsphotonics.1c00299

GaAs/AlGaAs Nanowire Array Solar Cell Grown on Si with Ultrahigh Power-per-Weight Ratio
DOI: 10.1021/acsphotonics.1c00527

Dual Nanoresonators for Ultrasensitive Chiral Detection
DOI: 10.1021/acsphotonics.1c00311

Quantum Nanophotonics in Two-Dimensional Materials
DOI: 10.1021/acsphotonics.0c01224


ACS Physical Chemistry Au
***
Insights into the Formations of Host–Guest Complexes Based on the Benzimidazolium Based Ionic Liquids -Cyclodextrin Systems

DOI: 10.1021/acsphyschemau.1c00016

Photocorrosion of WO3 Photoanodes in Different Electrolytes

DOI: 10.1021/acsphyschemau.1c00004

Performing Molecular Dynamics Simulations and Computing Hydration Free Energies on the B3LYP-D3(BJ) Potential Energy Surface with Adaptive Force Matching: A Benchmark Study with Seven Alcohols and One Amine

DOI: 10.1021/acsphyschemau.1c00006

Structural Water Molecules Confined in Soft and Hard Nanocavities as Bright Color Emitters
DOI: 10.1021/acsphyschemau.1c00020

Funding Mandates and the Launch of Nine Fully Open Access ACS Au Journals
DOI: 10.1021/acsphyschemau.1c00003


ACS Polymers Au
***
Safer and Greener Polymer Demonstrations for STEM Outreach
DOI: 10.1021/acspolymersau.1c00019

One-Pot Preparation of Methacrylate/Styrene Alternating Copolymers via Radical Copolymerization and Alcoholysis Modification: Sequence Impacts on Glass Transition Temperature

DOI: 10.1021/acspolymersau.1c00012

Directly Probing the Fracture Behavior of Ultrathin Polymeric Films

DOI: 10.1021/acspolymersau.1c00005

Tuning the Cloud-Point and Flocculation Temperature of Poly(2-(diethylamino)ethyl methacrylate)-Based Nanoparticles via a Postpolymerization Betainization Approach
DOI: 10.1021/acspolymersau.1c00010

Machine Learning Enhanced Computational Reverse Engineering Analysis for Scattering Experiments (CREASE) to Determine Structures in Amphiphilic Polymer Solutions
DOI: 10.1021/acspolymersau.1c00015


ACS Sensors
***
Flow-Through Quantification of Microplastics Using Impedance Spectroscopy

DOI: 10.1021/acssensors.0c02223

Highly Sensitive Porous PDMS-Based Capacitive Pressure Sensors Fabricated on Fabric Platform for Wearable Applications
DOI: 10.1021/acssensors.0c02122

Detecting COVID-19 from Breath: A Game Changer for a Big Challenge

DOI: 10.1021/acssensors.1c00312

Spatial Bias in Antibody Microarrays May Be an Underappreciated Source of Variability
DOI: 10.1021/acssensors.0c02613

In Vivo Platelet Detection Using a Glycoprotein IIb/IIIa-Targeted Near-Infrared Fluorescence Imaging Probe

DOI: 10.1021/acssensors.1c00124


ACS Sustainable Chemistry & Engineering
***
Solar-Driven Water Splitting at 13.8% Solar-to-Hydrogen Efficiency by an Earth-Abundant Electrolyzer

DOI: 10.1021/acssuschemeng.1c03565

Saline Water-Based Mineralization Pathway for Gigatonne-Scale CO2 Management
DOI: 10.1021/acssuschemeng.0c08561

Roadmap to Biodegradable Plastics—Current State and Research Needs
DOI: 10.1021/acssuschemeng.1c00801

Managing Plastic Waste Sorting, Recycling, Disposal, and Product Redesign
DOI: 10.1021/acssuschemeng.1c05013

Converting CO2 into an Oxygenated Alkynyl Carbon Material with High Electrochemical Performance through a Mechanochemical Reaction with CaC2

DOI: 10.1021/acssuschemeng.1c01318


ACS Synthetic Biology
***
A Whole-Cell Biosensor for Point-of-Care Detection of Waterborne Bacterial Pathogens

DOI: 10.1021/acssynbio.0c00491

CRISPR-Cas13 System as a Promising and Versatile Tool for Cancer Diagnosis, Therapy, and Research

DOI: 10.1021/acssynbio.1c00107

Cell-free Directed Evolution of a Protease in Microdroplets at Ultrahigh Throughput

DOI: 10.1021/acssynbio.0c00538

Modular Synthetic Biology Toolkit for Filamentous Fungi

DOI: 10.1021/acssynbio.1c00260

Mutation Maker, An Open Source Oligo Design Platform for Protein Engineering

DOI: 10.1021/acssynbio.0c00542


Analytical Chemistry
***
Multiplexed CuAAC Suzuki–Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling

DOI: 10.1021/acs.analchem.0c04726

Zero- to Ultralow-Field NMR Spectroscopy of Small Biomolecules

DOI: 10.1021/acs.analchem.0c04738

SHydrogen–Deuterium Exchange Mass Spectrometry with Integrated Size-Exclusion Chromatography for Analysis of Complex Protein Samples

DOI: 10.1021/acs.analchem.1c01171

Leakless, Bipolar Reference Electrodes: Fabrication, Performance, and Miniaturization

DOI: 10.10.1021/acs.analchem.1c00675

Successive High-Resolution (H2O)n-GCIB and C60-SIMS Imaging Integrates Multi-Omics in Different Cell Types in Breast Cancer Tissue

DOI: 10.1021/acs.analchem.0c05311


Biochemistry
***
Protein Substrates Engage the Lumen of O-GlcNAc Transferase’s Tetratricopeptide Repeat Domain in Different Ways

DOI: 10.1021/acs.biochem.0c00981

Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design

DOI: 10.1021/acs.biochem.0c00912

Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation

DOI: 10.1021/acs.biochem.1c00279

Buffers, Especially the Good Kind
DOI: 10.1021/acs.biochem.1c00200

Live and Let Dye

DOI: 10.1021/acs.biochem.1c00299


Bioconjugate Chemistry
***

Site-Specific Conjugation Strategy for Dual Antibody–Drug Conjugates Using Aerobic Formylglycine-Generating Enzymes
DOI: 10.1021/acs.bioconjchem.1c00246

A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid
DOI: 10.1021/acs.bioconjchem.1c00134

Generation and Biological Evaluation of Fc Antigen Binding Fragment-Drug Conjugates as a Novel Antibody-Based
DOI: 10.1021/acs.bioconjchem.1c00240

Flavin-tag: A Facile Method for Site-Specific Labeling of Proteins with a Flavin Fluorophore

DOI: 10.1021/acs.bioconjchem.1c00306

Site-Specific and Stable Conjugation of the SARS-CoV-2 Receptor-Binding Domain to Liposomes in the Absence of Any Other Adjuvants Elicits Potent Neutralizing Antibodies in BALB/c Mice
DOI: 10.1021/acs.bioconjchem.1c00463


Biomacromolecules
***
An Inverse Thermogelling Bioink Based on an ABA-Type Poly(2-oxazoline) Amphiphile

DOI: 10.1021/acs.biomac.1c00427

Hydrogel-Forming Algae Polysaccharides: From Seaweed to Biomedical Applications

DOI: 10.1021/acs.biomac.0c01406

Dual pH-Responsive Macrophage-Targeted Isoniazid Glycoparticles for Intracellular Tuberculosis Therapy

DOI: 10.1021/acs.biomac.1c00554

Crucial Impact of Residue Chirality on the Gelation Process and Biodegradability of Thermoresponsive Polypeptide Hydrogels

DOI: 10.1021/acs.biomac.1c00785

Red Blood Cell Cryopreservation with Minimal Post-Thaw Lysis Enabled by a Synergistic Combination of a Cryoprotecting Polyampholyte with DMSO/Trehalose

DOI: 10.1021/acs.biomac.1c01165


Chemical Research in Toxicology
***
Benzophenone Accumulates over Time from the Degradation of Octocrylene in Commercial Sunscreen Products

DOI: 10.1021/acs.chemrestox.0c00461

LC–MS/MS Analysis of the Formation and Loss of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer through Inhalation
DOI: 10.1021/acs.chemrestox.0c00404

Impact of e-Liquid Composition, Coil Temperature, and Puff Topography on the Aerosol Chemistry of Electronic Cigarettes
DOI: 10.1021/acs.chemrestox.1c00070

Cannabis Vaping: Existing and Emerging Modalities, Chemistry, and Pulmonary Toxicology
DOI: 10.1021/acs.chemrestox.1c00290

Post-Mortem Metabolomics: A Novel Approach in Clinical Biomarker Discovery and a Potential Tool in Death Investigations
DOI: 10.1021/acs.chemrestox.0c00448


Chemical Reviews
***
Recent Advances in Catalytic Asymmetric Construction of Atropisomers

DOI: 10.1021/acs.chemrev.0c01306

Two-Dimensional Metal-Organic Framework Materials: Synthesis, Structures, Properties and Applications
DOI: 10.1021/acs.chemrev.0c01049

Technological Innovations in Photochemistry for Organic Synthesis: Flow Chemistry, High-Throughput Experimentation, Scale-up, and Photoelectrochemistry

DOI: 10.1021/acs.chemrev.1c00332

Direct Photocatalyzed Hydrogen Atom Transfer (HAT) for Aliphatic C–H Bonds Elaboration

DOI: 10.1021/acs.chemrev.1c00263

Combining Machine Learning and Computational Chemistry for Predictive Insights Into Chemical Systems
DOI: 10.1021/acs.chemrev.1c00107


Chemistry of Materials
***
My Manuscript Was “Rejected without Review” from Chemistry of Materials: A Lesson in Burying the Lede

DOI: 10.1021/acs.chemmater.1c03512

Style Guides and the Garlic, Shallots, and Butter of Scientific Writing

DOI: 10.1021/acs.chemmater.1c01612

Covalent Organic Framework-Based Electrolytes for Fast Li+ Conduction and High-Temperature Solid-State Lithium-Ion Batteries

DOI: 10.1021/acs.chemmater.1c00978

Lowering Ternary Oxide Synthesis Temperatures by Solid-State Cometathesis Reactions
DOI: 10.1021/acs.chemmater.1c00700

Organic Enantiomeric Ferroelectrics with High Piezoelectric Performance: Imidazolium l- and d-Camphorsulfonate

DOI: 10.1021/acs.chemmater.1c01663


Crystal Growth & Design
***
Phase Field Modelling of Morphologies Driven by Tetragonal Interfacial Energy Anisotropy

DOI: 10.1021/acs.cgd.0c01424

Computational Screening of Chiral Organic Semiconductors: Exploring Side-Group Functionalization and Assembly to Optimize Charge Transport

DOI: 10.1021/acs.cgd.1c00473

Advances of Nonclassical Crystallization toward Self-Purification of Precious Metal Nanoparticle Mixtures
DOI: 10.1021/acs.cgd.1c00544

Advances in Low-Frequency Vibrational Spectroscopy and Applications in Crystal Engineering

DOI: 10.1021/acs.cgd.1c00850

Crystals and Crystallization in Drug Delivery Design

DOI: 10.1021/acs.cgd.0c01592


Energy & Fuels
***
Review on Ammonia as a Potential Fuel: From Synthesis to Economics
DOI: 10.1021/acs.energyfuels.0c03685

VHigh-Voltage “Single-Crystal” Cathode Materials for Lithium-Ion Batteries
DOI: 10.1021/acs.energyfuels.0c03608

Review on Ammonia as a Potential Fuel: From Synthesis to Economics

DOI: 10.1021/acs.energyfuels.0c03685

Recent Advances in Rechargeable Li–CO2 Batteries

DOI: 10.1021/acs.energyfuels.1c00635

Phosphate Polyanion Materials as High-Voltage Lithium-Ion Battery Cathode: A Review
DOI: 10.1021/acs.energyfuels.1c01102


Environmental Science & Technology
***

DOI: 10.1021/acs.est.1c05207

ES&T in the 21st Century: A Data-Driven Analysis of Research Topics, Interconnections, And Trends in the Past 20 Years
DOI: 10.1021/acs.est.0c07551

Life Cycle Assessment of Direct Air Carbon Capture and Storage with Low-Carbon Energy Sources
DOI: 10.1021/acs.est.1c03263

Deep Dive into Plastic Monomers, Additives, and Processing Aids

DOI: 10.1021/acs.est.1c00976

Log Mean Divisia Index Decomposition Analysis of the Demand for Building Materials: Application to Concrete, Dwellings, and the U.K.
DOI: 10.1021/acs.est.0c02387


Environmental Science & Technology Letters
***
Fluorinated Compounds in North American Cosmetics
DOI: 10.1021/acs.estlett.1c00240

Letters Cannabis and the Environment: What Science Tells Us and What We Still Need to Know
DOI: 10.1021/acs.estlett.0c00844

Exhaled CO2 as a COVID-19 Infection Risk Proxy for Different Indoor Environments and Activities
DOI: 10.1021/acs.estlett.1c00183

Respiratory Aerosol Emissions from Vocalization: Age and Sex Differences Are Explained by Volume and Exhaled CO2
DOI: 10.1021/acs.estlett.1c00760

Community Transmission of SARS-CoV-2 by Surfaces: Risks and Risk Reduction Strategies
DOI: 10.1021/acs.estlett.0c00966


Industrial & Engineering Chemistry Research
***
Industrial Requirements for Thermodynamic and Transport Properties: 2020
DOI: 10.1021/acs.iecr.0c05356

Process Systems Engineering Perspective on the Design of Materials and Molecules
DOI: 10.1021/acs.iecr.0c05399

Methane Pyrolysis for Zero-Emission Hydrogen Production: A Potential Bridge Technology from Fossil Fuels to a Renewable and Sustainable Hydrogen Economy
DOI: 10.1021/acs.iecr.1c01679

Wax Recovery from the Pyrolysis of Virgin and Waste Plastics
DOI: 10.1021/acs.iecr.1c01176

Identification of Known and Novel Monomers for Poly(hydroxyurethanes) from Biobased Materials
DOI: 10.1021/acs.iecr.0c06351


Inorganic Chemistry
***
Optical and Infrared Spectroelectrochemical Studies of CN-Substituted Bipyridyl Complexes of Ruthenium(II)
DOI: 10.1021/acs.inorgchem.0c03579

Complexation of Lanthanides and Heavy Actinides with Aqueous Sulfur-Donating Ligands
DOI: 10.1021/acs.inorgchem.1c00257

Revisiting the Electronic Structure of Cobalt Porphyrin Nitrene and Carbene Radicals with NEVPT2-CASSCF Calculations: Doublet versus Quartet Ground States
DOI: 10.1021/acs.inorgchem.1c00910

Tuning the Electronic Structure of Atomically Precise Sn/Co/Se Nanoclusters via Redox Matching of Tin(IV) Surface Sites
DOI: 10.1021/acs.inorgchem.1c00313

Iridium-Triggered Allylcarbamate Uncaging in Living Cells
DOI: 10.1021/acs.inorgchem.1c01790


JACS Au
***
Catalytic Hydrogenation of Polyurethanes to Base Chemicals: From Model Systems to Commercial and End-of-Life Polyurethane Materials
DOI: 10.1021/jacsau.1c00050

Alcohol-Assisted Hydrogenation of Carbon Monoxide to Methanol Using Molecular Manganese Catalysts
DOI: 10.1021/jacsau.0c00091

Deep Learning Optical Spectroscopy Based on Experimental Database: Potential Applications to Molecular Design
DOI: 10.1021/jacsau.1c00035

Thiol-Mediated Uptake
DOI: 10.1021/jacsau.1c00128

Luminescent First-Row Transition Metal Complexes
DOI: 10.1021/jacsau.1c00353


Journal of Agricultural and Food Chemistry
***

https://pubs.acs.org/doi/full/10.1021/acs.jafc.1c03897

Dysregulation of ClpP by Small-Molecule Activators Used Against Xanthomonas oryzae pv. oryzae Infections
DOI: 10.1021/acs.jafc.1c01470

Unraveling the Ergot Alkaloid and Indole Diterpenoid Metabolome in the Claviceps purpurea Species Complex Using LC–HRMS/MS Diagnostic Fragmentation Filtering
DOI: 10.1021/acs.jafc.1c01973

Phytochemical Flavone Confers Broad-Spectrum Tolerance to Insecticides in Spodoptera litura by Activating ROS/CncC-Mediated Xenobiotic Detoxification Pathways
DOI: 10.1021/acs.jafc.1c02695

Enhanced Extracellular Production of IsPETase in Escherichia coli via Engineering of the pelB Signal Peptide
DOI: 10.1021/acs.jafc.0c07469

Effect of the Stereoselectivity of para-Menthane-3,8-diol Isomers on Repulsion toward Aedes albopictus
DOI: 10.1021/acs.jafc.1c03897


Journal of Chemical & Engineering Data
***
Effect of Water Content on Thermodynamic Properties of Compressed Hydrogen
DOI: 10.1021/acs.jced.1c00020

Diffusivities in Binary Mixtures of n-Hexane or 1-Hexanol with Dissolved CH4, Ne, Kr, R143a, SF6, or R236fa Close to Infinite Dilution
DOI: 10.1021/acs.jced.1c00084

Engineering Model for Predicting the Intradiffusion Coefficients of Hydrogen and Oxygen in Vapor, Liquid, and Supercritical Water based on Molecular Dynamics Simulations
DOI: 10.1021/acs.jced.1c00300

Effect of Water Content on Thermodynamic Properties of Compressed Hydrogen
DOI: 10.1021/acs.jced.1c00020

Engineering Model for Predicting the Intradiffusion Coefficients of Hydrogen and Oxygen in Vapor, Liquid, and Supercritical Water based on Molecular Dynamics Simulations
DOI: 10.1021/acs.jced.1c00300


Journal of Chemical Education
***
Students’ Procedure When Solving Problem Tasks Based on the Periodic Table: An Eye-Tracking Study
DOI: 10.1021/acs.jchemed.1c00167

Decolonizing the Undergraduate Chemistry Curriculum: An Account of How to Start

DOI: 10.1021/acs.jchemed.1c00397

Fabricating a Low-Cost Raman Spectrometer to Introduce Students to Spectroscopy Basics and Applied Instrument Design
DOI: 10.1021/acs.jchemed.0c01028

Backward Design of Chemistry Laboratories: A Primer
DOI: 10.1021/acs.jchemed.1c00443

LAB Theory, HLAB Pedagogy, and Review of Laboratory Learning in Chemistry during the COVID-19 Pandemic
DOI: 10.1021/acs.jchemed.1c00457


Journal of Chemical Information and Modeling
***
AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings
DOI: 10.1021/acs.jcim.1c00203

Call for Papers for the Special Issue: From Reaction Informatics to Chemical Space
DOI: 10.1021/acs.jcim.1c00321

Wrapping Up Viruses at Multiscale Resolution: Optimizing PACKMOL and SIRAH Execution for Simulating the Zika Virus
DOI: 10.1021/acs.jcim.0c01205

Benchmarking the Ability of Common Docking Programs to Correctly Reproduce and Score Binding Modes in SARS-CoV-2 Protease Mpro
DOI: 10.1021/acs.jcim.1c00263

True Accuracy of Fast Scoring Functions to Predict High-Throughput Screening Data from Docking Poses: The Simpler the Better
DOI: 10.1021/acs.jcim.1c00292


Journal of Chemical Theory and Computation
***
TorchMD: A Deep Learning Framework for Molecular Simulations
DOI: 10.1021/acs.jctc.0c01343

Machine Learning in QM/MM Molecular Dynamics Simulations of Condensed-Phase Systems
DOI: 10.1021/acs.jctc.0c01112

Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane
DOI: 10.1021/acs.jctc.1c00536

Force Field Optimization Guided by Small Molecule Crystal Lattice Data Enables Consistent Sub-Angstrom Protein–Ligand Docking
DOI: 10.1021/acs.jctc.0c01184

Tinker-HP: Accelerating Molecular Dynamics Simulations of Large Complex Systems with Advanced Point Dipole Polarizable Force Fields Using GPUs and Multi-GPU Systems
DOI: 10.1021/acs.jctc.0c01164


Journal of Medicinal Chemistry
***
Small Molecule Kinase Inhibitor Drugs (1995–2021): Medical Indication, Pharmacology, and Synthesis
DOI: 10.1021/acs.jmedchem.1c00963

Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion
DOI: 10.1021/acs.jmedchem.0c01895

Lessons in Drug Design
DOI: 10.1021/acs.jmedchem.1c00975

A Decade of FDA-Approved Drugs (2010–2019): Trends and Future Directions
DOI: 10.1021/acs.jmedchem.0c01516

Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12D Inhibitor
DOI: 10.1021/acs.jmedchem.1c01688


Journal of Natural Products
***
Anti-SARS-CoV-2 Activity of Andrographis paniculata Extract and Its Major Component Andrographolide in Human Lung Epithelial Cells and Cytotoxicity Evaluation in Major Organ Cell Representatives

DOI: 10.1021/acs.jnatprod.0c01324

Professor A. Douglas Kinghorn. A Lifetime Career Dedicated to Outstanding Service to Natural Product Sciences
DOI: 10.1021/acs.jnatprod.0c01371

9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology
DOI: 10.1021/acs.jnatprod.1c00513

Freshwater Fungi as a Source of Chemical Diversity: A Review
DOI: 10.1021/acs.jnatprod.0c01340

Rufomycins or Ilamycins: Naming Clarifications and Definitive Structural Assignments
DOI: 10.1021/acs.jnatprod.1c00198


Journal of Proteome Research
***
Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer’s Disease
DOI: 10.1021/acs.jproteome.1c00558

NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines
DOI: 10.1021/acs.jproteome.0c00876

Mass Spectrometry-Based De Novo Sequencing of Monoclonal Antibodies Using Multiple Proteases and a Dual Fragmentation Scheme
DOI: 10.1021/acs.jproteome.1c00169

Surveying the Vampire Bat (Desmodus rotundus) Serum Proteome: A Resource for Identifying Immunological Proteins and Detecting Pathogens
DOI: 10.1021/acs.jproteome.0c00995

Characterization of Citrullination Sites in Neutrophils and Mast Cells Activated by Ionomycin via Integration of Mass Spectrometry and Machine Learning
DOI: 10.1021/acs.jproteome.1c00028


Journal of the American Chemical Society
***
Stereoselective Synthesis of Cyclobutanes by Contraction of Pyrrolidines
DOI: 10.1021/jacs.1c10175

Capturing the Moment of Emergence of Crystal Nucleus from Disorder
DOI: 10.1021/jacs.0c12100

Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3, and CF3 Reactivity
DOI: 10.1021/jacs.1c02606

Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
DOI: 10.1021/jacs.0c10008

The Open Reaction Database
DOI: 10.1021/jacs.1c09820


Journal of the American Society for Mass Spectrometry
***
Spatially Resolved Mass Spectrometry at the Single Cell: Recent Innovations in Proteomics and Metabolomics
DOI: 10.1021/jasms.0c00439

The Time Has Come for Quantitative Protein Mass Spectrometry Tests That Target Unmet Clinical Needs
DOI: 10.1021/jasms.0c00415

Liquid Chromatography–Electron Capture Negative Ionization–Tandem Mass Spectrometry Detection of Pesticides in a Commercial Formulation
DOI: 10.1021/jasms.0c00379

Highly Multiplexed Immunohistochemical MALDI-MS Imaging of Biomarkers in Tissues
DOI: 10.1021/jasms.0c00473

Ion Imaging of Native Protein Complexes Using Orthogonal Time-of-Flight Mass Spectrometry and a Timepix Detector
DOI: 10.1021/jasms.0c00412


Langmuir
***
Droplet-Based Membranous Soft Materials
DOI: 10.1021/acs.langmuir.0c03289

Liquid Crystals in Curved Confined Geometries: Microfluidics Bring New Capabilities for Photonic Applications and Beyond
DOI: 10.1021/acs.langmuir.1c00256

Benchmarking Cellulose Nanocrystals Part II: New Industrially Produced Materials
DOI: 10.1021/acs.langmuir.1c00550

Impact of Geometrical Disorder on Phase Equilibria of Fluids and Solids Confined in Mesoporous Materials
DOI: 10.1021/acs.langmuir.0c03047

Exploiting Additives for Directing the Adsorption and Organization of Colloid Particles at Fluid Interfaces
DOI: 10.1021/acs.langmuir.1c01029


Macromolecules
***
Controlled Ring-Opening Polymerization of Macrocyclic Monomers Based on the Quinone Methide Elimination Cascade Reaction
DOI: 10.1021/acs.macromol.1c00872

Diversity of Synthetic Approaches to Functionalized Perfluoropolyalkylether Polymers
DOI: 10.1021/acs.macromol.0c01599

Ion Correlations and Their Impact on Transport in Polymer-Based Electrolytes
DOI: 10.1021/acs.macromol.0c02545

Dienes Polymerization: Where We Are and What Lies Ahead
DOI: 10.1021/acs.macromol.1c00004

Deuteration and Polymers: Rich History with Great Potential
DOI: 10.1021/acs.macromol.0c02284


Molecular Pharmaceutics
***
COVID-19 Transmission, Current Treatment, and Future Therapeutic Strategies
DOI: 10.1021/acs.molpharmaceut.0c00608

Nanomedicines Beyond Cancer
DOI: 10.1021/acs.molpharmaceut.1c00022

Amorphous Drug Solubility and Maximum Free Drug Concentrations in Cyclodextrin Solutions: A Quantitative Study Using NMR Diffusometry
DOI: 10.1021/acs.molpharmaceut.1c00311

Mechanistic Model for the Prediction of Small-Molecule Vitreal Clearance Combining Diffusion-Limited and Permeability-Limited Clearance
DOI: 10.1021/acs.molpharmaceut.1c00236

Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging
DOI: 10.1021/acs.molpharmaceut.1c00285


Nano Letters
***
Electrochromic Inorganic Nanostructures with High Chromaticity and Superior Brightness
DOI: 10.1021/acs.nanolett.1c00904

Nanoscale Probing of Image-Potential States and Electron Transfer Doping in Borophene Polymorphs
DOI: 10.1021/acs.nanolett.0c04869

Atomic Point Contact Raman Spectroscopy of a Si(111)-7 × 7 Surface
DOI: 10.1021/acs.nanolett.1c00998

A New Perspective and Design Principle for Halide Perovskites: Ionic Octahedron Network (ION)
DOI: 10.1021/acs.nanolett.1c01897

Metal–Organic Frameworks Derived Functional Materials for Electrochemical Energy Storage and Conversion: A Mini Review
DOI: 10.1021/acs.nanolett.0c04898


Organic Letters
***
Coupling Photocatalysis and Substitution Chemistry to Expand and Normalize Redox-Active Halides
DOI: 10.1021/acs.orglett.1c00173

Aldehyde to Ketone Homologation Enabled by Improved Access to Thioalkyl Phosphonium Salts
DOI: 10.1021/acs.orglett.1c01189

Pd-Catalyzed Asymmetric Acyl-Carbamoylation of an Alkene to Construct an -Quaternary Chiral Cycloketone
DOI: 10.1021/acs.orglett.1c02093

Total Synthesis of ent-Plagiochianin B
DOI: 10.1021/acs.orglett.0c04219

Selective C–H Iodination of (Hetero)arenes
DOI: 10.1021/acs.orglett.1c01530


Organic Process Research & Development
***
Synthesis of Rovafovir Etalafenamide (Part I): Active Pharmaceutical Ingredient Process Development, Scale-Up, and Impurity Control Strategy
DOI: 10.1021/acs.oprd.1c00059

API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing
DOI: 10.1021/acs.oprd.0c00345

Integrated Continuous Pharmaceutical Technologies—A Review
DOI: 10.1021/acs.oprd.0c00504

Complexation of Polyethyleneglycol Containing Small Molecules with Magnesium Chloride as a Purification and Isolation Strategy
DOI: 10.1021/acs.oprd.1c00174

High-Throughput Electrochemistry: State of the Art, Challenges, and Perspective
DOI: 10.1021/acs.oprd.1c00167


Organometallics
***
A Tutorial on Selectivity Determination in C(sp2)–H Oxidative Addition of Arenes by Transition Metal Complexes
DOI: 10.1021/acs.organomet.1c00030

Synthesis of NHC-Iridium(III) Complexes Based on N-Iminoimidazolium Ylides and Their Use for the Amine Alkylation by Borrowing Hydrogen Catalysis
DOI: 10.1021/acs.organomet.0c00726

The Effect of Added Ligands on the Reactions of [Ni(COD)(dppf)] with Alkyl Halides: Halide Abstraction May Be Reversible
DOI: 10.1021/acs.organomet.1c00280

Terminal Mo Carbide and Carbyne Reactivity: H2 Cleavage, B–C Bond Activation, and C–C Coupling
DOI: 10.1021/acs.organomet.1c00336

Functionalization of RhIII–Me Bonds: Use of “Capping Arene” Ligands to Facilitate Me–X Reductive Elimination
DOI: 10.1021/acs.organomet.1c00223


The Journal of Organic Chemistry
***
An Organic Chemist’s Guide to N-Nitrosamines: Their Structure, Reactivity, and Role as Contaminants
DOI: 10.1021/acs.joc.0c02774

Rapid Estimation of T1 for Quantitative NMR
DOI: 10.1021/acs.joc.1c01007

“How Should I Think about Voltage? What Is Overpotential?”: Establishing an Organic Chemistry Intuition for Electrochemistry
DOI: 10.1021/acs.joc.1c01520

Isomerization and Fragmentation Reactions on the [C2SH4] Potential Energy Surface: The Metastable Thione S-Methylide Isomer
DOI: 10.1021/acs.joc.0c02835

“How Should I Think about Voltage? What Is Overpotential?”: Establishing an Organic Chemistry Intuition for Electrochemistry
DOI: 10.1021/acs.joc.1c01520


The Journal of Physical Chemistry A
***
Photoelectron Spectra of Gd2O2 and Nonmonotonic Photon-Energy-Dependent Variations in Populations of Close-Lying Neutral States
DOI: 10.1021/acs.jpca.0c11002

Aromatics and Cyclic Molecules in Molecular Clouds: A New Dimension of Interstellar Organic Chemistry
DOI: 10.1021/acs.jpca.1c00129

Proton Transfer in a Bare Superacid–Amine Complex: A Microwave and Computational Study of Trimethylammonium Triflate
DOI: 10.1021/acs.jpca.1c03345

Toward a Generalized Hückel Rule: The Electronic Structure of Carbon Nanocones
DOI: 10.1021/acs.jpca.1c06402

Aromatics and Cyclic Molecules in Molecular Clouds: A New Dimension of Interstellar Organic Chemistry
DOI: 10.1021/acs.jpca.1c00129


The Journal of Physical Chemistry B
***
Introducing Memory in Coarse-Grained Molecular Simulations
DOI: 10.1021/acs.jpcb.1c01120

Molecular Properties and Chemical Transformations Near Interfaces
DOI: 10.1021/acs.jpcb.1c06073

A Cuban Campesino in Chemistry’s Academic Court
DOI: 10.1021/acs.jpcb.1c07900

Effect of Buffer on Protein Stability in Aqueous Solutions: A Simple Protein Aggregation Model
DOI: 10.1021/acs.jpcb.0c10339

Quantum Simulations of Hydrogen Bonding Effects in Glycerol Carbonate Electrolyte Solutions
DOI: 10.1021/acs.jpcb.0c10942


The Journal of Physical Chemistry C
***
2D Electronic Spectroscopic Techniques for Quantum Technology Applications
DOI: 10.1021/acs.jpcc.1c02693

Experimental and Theoretical Study of the Electronic Structures of Lanthanide Indium Perovskites LnInO3
DOI: 10.1021/acs.jpcc.0c11592

Interfaces and Interfacial Carrier Dynamics in Perovskitesa
DOI: 10.1021/acs.jpcc.1c01849

Effects of the Wettability of a Probing Tip on the Hydration Layer Imaged in Atomic Force Microscopy
DOI: 10.1021/acs.jpcc.1c02022

Suggesting Reviewers to Improve Your Manuscript
DOI: 10.1021/acs.jpcc.1c05523


The Journal of Physical Chemistry Letters
***
The Peril of Politicizing Science
DOI: 10.1021/acs.jpclett.1c01475

Opportunities for Next-Generation Luminescent Materials through Artificial Intelligence
DOI: 10.1021/acs.jpclett.0c03203

Science Is Political, and We Must Deal with It
DOI: 10.1021/acs.jpclett.1c02017

Paving the Way to Establish Protocols: Modeling and Predicting Mechanochemical Reactions
DOI: 10.1021/acs.jpclett.1c01472

Cation-Driven Lipopolysaccharide Morphological Changes Impact Heterogeneous Reactions of Nitric Acid with Sea Spray Aerosol Particles
DOI: 10.1021/acs.jpclett.1c00810

Want more stories like this delivered to your inbox?

Sign up for our newsletter to receive a selection of stories related to your favorite topics.

  • This field is for validation purposes and should be left unchanged.