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Chemistry's Hot Topics: Explore Highly Read Articles in April 2026

Meredith Rountree

A cropped image from a JACS journal cover. The cover art visualizes a methodology to introduce structural order into hydrocarbon polymers.

Chemistry's Hot Topics: Explore Highly Read Articles in March 2026

3D illustration of a glowing gold tetrahedral molecular structure floating in a star‑filled, cosmic background, with smaller similar molecules surrounding it.

Chemistry's Hot Topics: Explore Highly Read Articles in February 2026

Abstract scientific illustration showing clusters of purple spherical particles embedded in a field of smaller blue spheres, with glowing lines and bubbles suggesting molecular interactions or energy transfer.

Chemistry's Hot Topics: Explore Highly Read Articles in January 2026

Cover art depicting a glowing cellular structure at the center of branching molecular networks, illuminated by a vertical beam of light, with chemical symbols such as NAD⁺ and H scattered throughout the scene, representing biochemical energy.

Chemistry's Hot Topics: Explore Highly Read Articles in December 2025

A transparent prism casting a rainbow gradient on a dark surface, with a molecular structure made of clear spheres and rods arranged in a chain pattern beneath the colorful light.

Chemistry's Hot Topics: Explore Highly Read Articles in November 2025

Colorful molecular chains surrounding a swirling blue vortex, representing dynamic chemical reactions or molecular energy transfer

Chemistry's Hot Topics: Explore Highly Read Articles in October 2025

A digital rendering of a molecular structure featuring a prism of visible light hitting it from the top.

Chemistry's Hot Topics: Explore Highly Read Articles in September 2025

The N-iodo Hammick intermediate, an N-heterocyclic carbene featuring σ/σ* frontier orbitals, adds molecular hydrogen at cryogenic temperatures in a matrix of solid neon, producing pyridinium iodide.

Chemistry's Hot Topics: Explore Highly Read Articles in August 2025

A library of carbonate-bearing ionizable lipids is developed for formulating lipid nanoparticles capable of delivering mRNA to the spleen following intravenous administration, effectively transfecting splenic natural killer (NK) cells.

Chemistry's Hot Topics: Explore Highly Read Articles in July 2025

A futuristic robotic insect with transparent wings and a blue light, positioned atop a high-tech surface with circuit patterns.

David Armstrong

The main building of the University of Catania

An artistic rendering of a nickel catalyst bearing a bifunctional ligand, encased in lightning to represent its electrochemical activation. Surrounding it, colorful proton sources direct identical substrates toward distinct outcomes, highlighting the power of acid choice in steering reactivity

A digital image depicting the solid–liquid interface of a palladium nanoparticle during reactions of hydrogen and oxygen to hydrogen peroxide in water. The nanoparticle is covered with organic residue, which promotes the catalysis. 

Abstract visualization of interconnected atoms in vibrant colors, illustrating complex molecular structures.

An abstract depiction of molecules and atoms, showcasing colorful spheres and electric currents against a blue background.

Artistic depiction of a protein structure amidst stylized cellular components, with a swirling background of vibrant colors, illustrating a biological or molecular scene.

a close-up of a liquid boiling with glowing orange and blue hues, with droplets suspended in mid-air. Overlaid on this scene is a molecular structure diagram in blue and black, resembling a porous material or catalyst, with red and white molecular representations of gases such as oxygen and hydrogen.

an interfacial electric-field-induced prototropic tautomerization reaction in an enzymatic-like nanopocket created by the atomically sharp gold electrodes using the mechanically controlled break junction (MCBJ) technique

Illustration of molecules interacting over a lattice of golden and silver spheres, representing a chemical reaction process.

Blue and purple molecular structures connect in a conceptual illustration, symbolizing biological interaction or protein bonding.

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