Stay up to date with a selection of recently published articles from ACS journals that were among the most read in June 2026.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 highly read chemistry articles during June 2026, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in ACS journals, click below to learn more and discover the best fit for your research.

A 50,688-Reaction Data Set Reveals General Ligands and Mechanistic Diversity in C–N Couplings
DOI: 10.1021/jacs.6c05959

Targeted Transcriptional Repression by Induced Proximity
DOI: 10.1021/acscentsci.5c02277

Oxyalkylation of Alkenes via Triple Radical Sorting
DOI: 10.1021/jacs.6c03814

Shape-Conserving Atom Replacements
DOI: 10.1021/acs.chemrev.5c01009

Catalytic Asymmetric Hydration of Alkenes
DOI: 10.1021/jacs.6c06916

Storage Buffer Composition Impacts Internal Structure, Freeze–Thaw Stability, and Transfection Efficiency of mRNA-Lipid Nanoparticles
DOI: 10.1021/acsnano.5c22170

Piecewise Stereoselective Assembly of Multisubstituted Alkenes
DOI: 10.1021/jacs.6c09135

Asymmetric Total Synthesis of C2-OH Lycopodium Alkaloids (−)-Palhinine B, (−)-Palhinine C, and (+)-Palhinine B Enabled by Stereocontrolled Diels–Alder Strategy
DOI: 10.1021/acs.orglett.6c01704

Fe(porphyrin)-Catalyzed Alkene Epoxidation with NaOCl: A Practical Small- and Large-Scale Alternative to mCPBA
DOI: 10.1021/jacs.6c06785

Visible-Light-Mediated Pyridine-N-oxide-Assisted Alkoxycarbonyl Chlorination of Alkenes via Iron-Catalyzed Radical Ligand Transfer
DOI: 10.1021/acscatal.6c03087
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what articles attracted the most attention in a particular month.
