Stay up to date with a selection of recently published articles from ACS journals that were among the most read in June 2026.

A cropped image from a JACS journal cover, depicting A pyrrolidine dimer adsorbed on a Cu(100) surface operates as an energy-efficient, multilevel molecular switch.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 highly read chemistry articles during June 2026, showcasing influential and trending research across ACS journals.*

We hope you find these articles insightful and valuable. If you want to learn more about publishing in ACS journals, click below to learn more and discover the best fit for your research.

Browse Highly Read ACS Journal Articles in June 2026
ACS Central Sciece Journal Cover

Targeted Transcriptional Repression by Induced Proximity

Christian E. Stieger, Xinru Chen, Christina C. Kuismi, Dustin Dovala, Daniel Fuller, Andreas O. Frank, Mikias Woldegiorgis, Megan Bruce-Smythe, Fabian Wu, Nicolas Pizzato, Jeffrey McKenna, Cory Johannessen, Barna D. Fodor, Markus Schirle, and Daniel K. Nomura*
DOI: 10.1021/acscentsci.5c02277
JACS Journal Cover

Catalytic Asymmetric Hydration of Alkenes

Hibiki Hatano, Vitor Alcantara Fernandes, Subrata Mukherjee, Chendan Zhu, Akito Takahira, Pingyu Jiang, Mingoo Jin, Yu Harabuchi, Ruben Staub, Min Gao, Alexandre Varnek, Satoshi Maeda, Nobuya Tsuji*, and Benjamin List*
DOI: 10.1021/jacs.6c06916
ACS Nano Journal Cover

Storage Buffer Composition Impacts Internal Structure, Freeze–Thaw Stability, and Transfection Efficiency of mRNA-Lipid Nanoparticles

Meysam Mohammadi-Zerankeshi, Dylan J. Charland, Keira A. Donnelly, Geoffrey T. Nash, Jiale Shi, Dipak N. Patil, Julia Ennis, Kenneth G. Rodriguez, Sonia Corba, Noah A. Wambolt, Haocheng Chueh, Khaled AboulFotouh, Mohammed R. Kawelah, Younghoon Oh, Dennis Yang, Ken K. Qian, Qiang Cui, Keith P. Johnston, Daniel A. Estabrook*, and Alexander E. Marras*
DOI: 10.1021/acsnano.5c22170

*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what articles attracted the most attention in a particular month.

Want the latest stories delivered to your inbox each month?