Explore a selection of recently published chemistry articles that were among the most read in March 2024 across all ACS Publications journals.

There are many ways to measure an article’s success after it is published. One helpful method of evaluating a scientific publication’s reach and influence is by looking at how many times it has been read. Below, we have gathered a selection of recently published chemistry articles that were among the most read in March 2024 across all ACS Publications journals.*
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NMR Chemical Shifts of Trace Impurities: Industrially Preferred Solvents Used in Process and Green Chemistry
Nicholas R. Babij, Elizabeth O. McCusker, Gregory T. Whiteker*, Belgin Canturk, Nakyen Choy, Lawrence C. Creemer, Carl V. De Amicis, Nicole M. Hewlett, Peter L. Johnson, James A. Knobelsdorf, Fangzheng Li, Beth A. Lorsbach, Benjamin M. Nugent, Sarah J. Ryan, Michelle R. Smith, and Qiang Yang
DOI: 10.1021/acs.oprd.5b00417
DOI: 10.1021/acs.oprd.5b00417

Enantioselective Total Synthesis of (−)-Hunterine A Enabled by a Desymmetrization/Rearrangement Strategy
Elliot F. Hicks, Kengo Inoue, and Brian M. Stoltz*
DOI: 10.1021/jacs.3c13590
DOI: 10.1021/jacs.3c13590

Electrochemical Impedance Spectroscopy─A Tutorial
Alexandros Ch. Lazanas and Mamas I. Prodromidis*
DOI: 10.1021/acsmeasuresciau.2c00070
DOI: 10.1021/acsmeasuresciau.2c00070

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
Daniel W. Robbins, Mark A. Noviski, Ying Siow Tan, Zef A. Konst, Aileen Kelly, Paul Auger, Nivetha Brathaban, Robert Cass, Ming Liang Chan, Ganesh Cherala, Matthew C. Clifton, Stefan Gajewski, Timothy G. Ingallinera, Dane Karr, Daisuke Kato, Jun Ma, Jenny McKinnell, Joel McIntosh, Jeff Mihalic, Brent Murphy, Jaipal Reddy Panga, Ge Peng, Janine Powers, Luz Perez, Ryan Rountree, Austin Tenn-McClellan, Arthur T. Sands, Dahlia R. Weiss, Jeffrey Wu, Jordan Ye, Cristiana Guiducci, Gwenn Hansen, and Frederick Cohen*
DOI: 10.1021/acs.jmedchem.3c01007
DOI: 10.1021/acs.jmedchem.3c01007

A Dual Cobalt and Photoredox Catalysis for Hydrohalogenation of Alkenes
Shotaro Shibutani, Kazunori Nagao*, and Hirohisa Ohmiya*
DOI: 10.1021/jacs.3c10133
DOI: 10.1021/jacs.3c10133

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects
Yue Li, Le Tao, Qiong Wang, Fengbang Wang, Gang Li, and Maoyong Song*
DOI: 10.1021/envhealth.3c00052
DOI: 10.1021/envhealth.3c00052

Thompson Sampling─An Efficient Method for Searching Ultralarge Synthesis on Demand Databases
Kathryn Klarich, Brian Goldman, Trevor Kramer, Patrick Riley, and W. Patrick Walters*
DOI: 10.1021/acs.jcim.3c01790
DOI: 10.1021/acs.jcim.3c01790

Regiodivergent Ring-Expansion of Oxindoles to Quinolinones
Hendrik L. Schmitt, Den Martymianov, Ori Green, Tristan Delcaillau, Young Seo Park Kim, and Bill Morandi*
DOI: 10.1021/jacs.3c12119
DOI: 10.1021/jacs.3c12119

Activity of Gut-Derived Nisin-like Lantibiotics against Human Gut Pathogens and Commensals
Zhenrun J. Zhang*, Chunyu Wu, Ryan Moreira, Darian Dorantes, Téa Pappas, Anitha Sundararajan, Huaiying Lin, Eric G. Pamer*, and Wilfred A. van der Donk*
DOI: 10.1021/acschembio.3c00577
DOI: 10.1021/acschembio.3c00577

Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering
Jason Yang, Francesca-Zhoufan Li, and Frances H. Arnold*
DOI: 10.1021/acscentsci.3c01275
DOI: 10.1021/acscentsci.3c01275