Here, we discover the most-read chemistry articles across ACS journals in July 2020, including research, reviews, perspectives, and editorial pieces.

Celebrating Prof. Renato Zenobi at Ions and Photons in Analytical Science 2021

There are lots of different ways to look at the reach of an article. You can look at citations, Altmetric Attention Scores, awards, and more. One way to consider the influence of an article is just by looking at how many people chose to read it. To that end, we’ve compiled lists of the five most-read chemistry articles from each ACS Publications journal in July 2020, including research, reviews, perspectives, and editorial pieces. These lists were not chosen by the journal’s editors and should not be taken as a “best of” list, but as another perspective on where the chemistry community allocated their attention.

Click on your favorite journal below to see their most-read articles of the month.

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Synthesis of Bioactive Complex Small Molecule–Ciprofloxacin Conjugates and Evaluation of Their Antibacterial Activity
DOI: 10.1021/acscombsci.0c00060

Facile Synthesis of Novel Hexahydroimidazo[1,2-a]pyridine Derivatives by One-Pot, Multicomponent Reaction under Ambient Conditions
DOI: 10.1021/acscombsci.0c00105

One Reacts as Two: Applications of N-isocyaniminotriphenylphosphorane in Diversity-Oriented Synthesis
DOI: 10.1021/acscombsci.0c00111

Valence Band Modification of a (GaxIn1–x)2O3 Solid Solution System Fabricated by Combinatorial Synthesis
DOI: 10.1021/acscombsci.0c00033

Comprehensive Prediction of Molecular Recognition in a Combinatorial Chemical Space using Machine Learning
DOI: 10.1021/acscombsci.0c00003

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SMARCA2/4 PROTAC for Targeted Protein Degradation and Cancer Therapy
DOI: 10.1021/acsmedchemlett.0c00347

Chemically Induced Degradation of WEE1 Kinase for Difficult to Treat Diseases
DOI: 10.1021/acsmedchemlett.0c00345

Selective DYRK1A Inhibitor for the Treatment of Neurodegenerative Diseases: Alzheimer, Parkinson, Huntington, and Down Syndrome
DOI: 10.1021/acsmedchemlett.0c00346

Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors
DOI: 10.1021/acsmedchemlett.0c00195

GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family
DOI: 10.1021/acsmedchemlett.0c00247

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Catalytic Allylation of Aldehydes Using Unactivated Alkenes
DOI: 10.1021/jacs.0c04735

Total Synthesis of Tagetitoxin
DOI: 10.1021/jacs.0c06641

Synthesis of Cyclo[18]carbon via Debromination of C18Br6
Open Access Through ACS AuthorChoice
DOI: 10.1021/jacs.0c05033

Organocatalyzed Birch Reduction Driven by Visible Light
DOI: 10.1021/jacs.0c05899

Catalyst- and Silane-Controlled Enantioselective Hydrofunctionalization of Alkenes by Cobalt-Catalyzed Hydrogen Atom Transfer and Radical-Polar Crossover
DOI: 10.1021/jacs.0c05017

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Cholesterol Alters the Orientation and Activity of the Influenza Virus M2 Amphipathic Helix in the Membrane
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcb.0c03331

Breakage of Hydrophobic Contacts Limits the Rate of Passive Lipid Exchange between Membranes
DOI: 10.1021/acs.jpcb.0c04139

Ultrafast Excited State Dynamics and Fluorescence from Vitamin B12 and Organometallic [Co]–C≡C–R Cobalamins
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcb.0c04886

Chemical-State-Dependent Free Energy Profile from Single-Molecule Trajectories of Biomolecular Motors: Application to Processive Chitinase
DOI: 10.1021/acs.jpcb.0c02698

Application of Graphene as a Nanoindenter Interacting with Phospholipid Membranes—Computer Simulation Study
Open Access Through ACS AuthorChoice
DOI: 10.1021/acs.jpcb.0c02319

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