Stay up to date with a selection of recently published articles from ACS journals that were among the most read in August 2025.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during August 2025, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”

Total Synthesis of (−)-Neocucurbol C Enabled by Pattern Recognition and MHAT Cyclization
DOI: 10.1021/jacs.5c08224

Maternal Plasma Proteins Associated with Birth Weight: A Longitudinal, Large Scale Proteomic Study
DOI: 10.1021/acs.jproteome.4c00940

Total Synthesis of the Nominal Structure of (+)-Talaromyolide D
DOI: 10.1021/jacs.5c10325

Lessons Learned during 50 kg Manufacturing of Suzuki–Miyaura Coupling Reaction
DOI: 10.1021/acs.oprd.5c00207

Elevated Toxic Element Emissions from Popular Disposable E-Cigarettes: Sources, Life Cycle, and Health Risks
DOI: 10.1021/acscentsci.5c00641

Total Synthesis of (−)-Psathyrin A Enabled by Radical Cyclization
DOI: 10.1021/jacs.5c11534

A Data-Driven Perspective on Bioisostere Evaluation: Mapping the Benzene Bioisostere Landscape with BioSTAR
DOI: 10.1021/acs.jmedchem.5c01641

Enantioselective Total Synthesis of (−)-Novofumigatonin
DOI: 10.1021/jacs.5c10466

Deaminative Cyanation of Anilines by Oxylanion Radical Transfer
DOI: 10.1021/acs.orglett.5c02410

Tech-Enhanced Synthesis: Exploring the Synergy between Organic Chemistry and Technology
DOI: 10.1021/jacs.5c10303
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.