Stay up to date with a selection of recently published articles from ACS journals that were among the most read in May 2025.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during May 2025, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”

Hold My Beer: The Linkage between Municipal Water and Brewing Location on PFAS in Popular Beverages
DOI: 10.1021/acs.est.4c11265

Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World
DOI: 10.1021/acs.chemrestox.5c00033

Iron-Mediated Nitrate Reduction at Ambient Temperature for Deaminative Sulfonylation and Fluorination of Anilines
DOI: 10.1021/jacs.4c17981

Formaldehyde and Formaldehyde Releasing Preservatives in Personal Care Products Used by Black Women and Latinas
DOI: 10.1021/acs.estlett.5c00242

Total Synthesis of (−)-Illisimonin A Enabled by Pattern Recognition and Olefin Transposition
DOI: 10.1021/jacs.5c05409

Plug Flow: Generating Renewable Electricity with Water from Nature by Breaking the Limit of Debye Length
DOI: 10.1021/acscentsci.4c02110

10-Step, Gram-Scale Total Synthesis of (−)-Bipinnatin J
DOI: 10.1021/jacs.5c04761

A Perspective on the Strategic Application of Deconstruction–Reconstruction in Drug Discovery
DOI: 10.1021/acs.jmedchem.5c00036

The Invisible Footprint of Climbing Shoes: High Exposure to Rubber Additives in Indoor Facilities
DOI: 10.1021/acsestair.5c00017

Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations
DOI: 10.1021/jacs.5c03864
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.