Stay up to date with a selection of recently published articles from ACS journals that were among the most read in May 2025.

A digital image depicting the solid–liquid interface of a palladium nanoparticle during reactions of hydrogen and oxygen to hydrogen peroxide in water. The nanoparticle is covered with organic residue, which promotes the catalysis.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during May 2025, showcasing influential and trending research across ACS journals.*

We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”

Browse Highly Read ACS Journal Articles in May 2025
Chemical Research in Toxicology Journal Cover

Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World

Srijit Seal*, Manas Mahale, Miguel García-Ortegón, Chaitanya K. Joshi, Layla Hosseini-Gerami, Alex Beatson, Matthew Greenig, Mrinal Shekhar, Arijit Patra, Caroline Weis, Arash Mehrjou, Adrien Badré, Brianna Paisley, Rhiannon Lowe, Shantanu Singh, Falgun Shah, Bjarki Johannesson, Dominic Williams, David Rouquie, Djork-Arné Clevert, Patrick Schwab, Nicola Richmond, Christos A. Nicolaou, Raymond J. Gonzalez, Russell Naven, Carolin Schramm, Lewis R Vidler, Kamel Mansouri, W. Patrick Walters, Deidre Dalmas Wilk, Ola Spjuth*, Anne E. Carpenter*, and Andreas Bender*
DOI: 10.1021/acs.chemrestox.5c00033

*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what recently published research attracted the most attention in a particular month.

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