Stay up to date with a selection of recently published articles from ACS journals that were among the most read in January 2026.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 most-read chemistry articles during January 2026, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in our journals, click below to discover how your own research can further our commitment to being the “Most Trusted. Most Cited. Most Read.”

Quality over Quantity: Organic Compounds Altering the Antarctic Sea Spray Aerosol Concentrations
DOI: 10.1021/acs.est.5c07574

Cross-Electrophile Coupling of N-Hydroxyphthalimide Esters with Aryl Bromides Using an Inner-Sphere Homogeneous Reductant
DOI: 10.1021/jacs.5c18451

Allosteric PROTACs: Expanding the Horizon of Targeted Protein Degradation
DOI: 10.1021/jacs.5c14840

What Do Oral Drugs Really Look Like? Dose Regimen, Pharmacokinetics, and Safety of Recently Approved Small-Molecule Oral Drugs
DOI: 10.1021/acs.jmedchem.5c02863

Unified Synthesis Platform for 1,2,3-Trisubstituted Cyclopentadienyl Ligands Decouples Sterics from Electronics
DOI: 10.1021/jacs.5c20631

Best Practices for Using AI When Writing Scientific Manuscripts
DOI: 10.1021/acsnano.3c01544

Photolysis of CO2 Carbamate for Hydrocarboxylation Reactions
DOI: 10.1021/jacs.5c21208

Room-Temperature Metal-Catalyzed Hydrogen Borrowing Alkylation
DOI: 10.1021/acscatal.5c07305

16-Step Scalable Chemoenzymatic Synthesis of Tetrodotoxin
DOI: 10.1021/jacs.5c20700

Electrochemical Indole Skeletal Editing via Single-Carbon Atom Insertion
DOI: 10.1021/jacs.5c19912
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what articles attracted the most attention in a particular month.
