Stay up to date with a selection of recently published articles from ACS journals that were among the most read in April 2026.
The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 highly read chemistry articles during April 2026, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in ACS journals, click below to learn more and discover the best fit for your research.
Browse Highly Read ACS Journal Articles in April 2026
Radical Sampling Enabled Saturated N-Heterocycle Cyclization
Qinyan Cai, Noah B. Bissonnette, Saegun Kim, Thomas Knauber, Gary M. Chinigo, David C. Blakemore, and David W. C. MacMillan*
DOI: 10.1021/jacs.6c01294
DOI: 10.1021/jacs.6c01294
Quantitation of Vitamin B6 Vitamers and Glycosides in German Alcohol-Free and Full-Strength Beer by a Stable Isotope Dilution LC–MS/MS Method
Simone Jahner, Elias Geilich, Carina Hagenauer, and Michael Rychlik*
DOI: 10.1021/acs.jafc.5c14229
DOI: 10.1021/acs.jafc.5c14229
Seven-Step Total Synthesis of Conidiogenone B Enabled by Radical Cyclizations
Josephine Bernard, Ziyao Zhang, and Mingji Dai*
DOI: 10.1021/jacs.6c02334
DOI: 10.1021/jacs.6c02334
Propellane Alkaloid Biosynthesis and Total Synthesis via Interrupted Reaction Pathways
John M. Billingsley, Jiaming Ding, Allison T. Hands, Kanji Niwa, Nathan J. Adamson, Lukas A. Wein, Bruno Perlatti, Neil K. Garg*, and Yi Tang*
DOI: 10.1021/acscentsci.6c00057
DOI: 10.1021/acscentsci.6c00057
Rethinking the Terms “π-Stacking” and “π–π Stacking” Again: A Proposal to Clarify the Language of Aromatic Interactions
Qifan Xiao, Matthew S. Levine, and Brent L. Iverson*
DOI: 10.1021/jacs.6c03371
DOI: 10.1021/jacs.6c03371
Reactive Machine Learning Interatomic Potentials for Chemistry and Materials Science
Jisu Kim, Hyunsung Cho, Haekwan Jeon, Jisu Jung*, and Seungwu Han*
DOI: 10.1021/acs.chemrev.5c00728
DOI: 10.1021/acs.chemrev.5c00728
Total Synthesis of Ussuriedine via a Late-Stage Stevens Rearrangement: Implications for Biosynthesis
Daler Baidilov, Kyle J. Cassaidy, Yun-Jeong Shin, and Viresh H. Rawal*
DOI: 10.1021/jacs.6c00926
DOI: 10.1021/jacs.6c00926
Discovery of AMG 133, a Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonist and Glucagon-Like Peptide 1 Receptor Agonist Antibody-Drug Conjugate for the Treatment of Obesity
Bin Wu*, James R. Falsey, Chawita Netirojjanakul, Brad Herberich, Jerry Ryan Holder, Kelvin Sham, Jennifer Aral, Neil Forsythe, Kenneth W. Walker, Shu-Chen Lu, Todd Hager, Shanaka Stanislaus, Renee Komorowski, Larissa Atangan, Michal Achmatowicz, Dante Romanini, Dohan Weeraratne, Les P. Miranda, Murielle M. Véniant, and Yuan Cheng*
DOI: 10.1021/acs.jmedchem.6c00032
DOI: 10.1021/acs.jmedchem.6c00032
Direct Access to Iron Carbenes from Aldehyde, Ketone, and Formamide Feedstocks
P. Scott Pedersen, Katherine I. Burton, Sven H. M. Kaster, Eva Lin, Andria L. Pace, Marian C. Bryan, Taylor M. Sodano, Nicholas E. Intermaggio, Christopher B. Kelly, and David W. C. MacMillan*
DOI: 10.1021/jacs.5c21614
DOI: 10.1021/jacs.5c21614
n-BuLi-Catalyzed Amidation Reactions of Aldehydes with 1° Amines
Yujie Su, Yi Zhang, Xuehua Zhu*, Dan Yuan*, and Yingming Yao*
DOI: 10.1021/acs.orglett.6c01054
DOI: 10.1021/acs.orglett.6c01054
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what articles attracted the most attention in a particular month.
