Stay up to date with a selection of recently published articles from ACS journals that were among the most read in March 2026.

The impact of a scientific article can be assessed in many ways, and one key indicator of reach and influence is its readership. Here, we present a curated list of 10 highly read chemistry articles during March 2026, showcasing influential and trending research across ACS journals.*
We hope you find these articles insightful and valuable. If you want to learn more about publishing in ACS journals, click below to learn more and discover the best fit for your research.

Molecular Design with Artificial Intelligence: Progress and Perspectives for Small Molecules
DOI: 10.1021/acs.chemrev.5c00689

Boron-Mediated Hydroalkylation of Unactivated Olefins: An Anti-Markovnikov Approach to Congested Carbon Centers
DOI: 10.1021/jacs.6c01091

BBB-Permeable PROTACs: Where Do We Stand?
DOI: 10.1021/acsmedchemlett.5c00768

Convergent Total Synthesis of Caribbean Ciguatoxin C-CTX1 and Its C3-Epimer
DOI: 10.1021/jacs.6c01247

Normalizing Covalent Potency for Electrophilicity with Ligand Reactivity Efficiency
DOI: 10.1021/acs.jmedchem.5c01803

Photodriven Sm-Catalyzed Asymmetric Ketyl-Olefin Coupling
DOI: 10.1021/jacs.5c20884

Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C
DOI: 10.1021/acs.jmedchem.5c02272

Aminyl Radical-Enabled Photoredox/Nickel-Catalyzed C(sp3)–C(sp3) Suzuki–Miyaura Cross-Coupling via Halogen-Atom Transfer Strategy
DOI: 10.1021/jacs.6c00526

Thianthrenium Salts in Photochemistry
DOI: 10.1021/acs.accounts.5c00863

Ortho–Meta and Para–Meta Isomerization of Phenols
DOI: 10.1021/jacs.6c00742
*These lists are not chosen by the journals’ editors and should not be taken as a “best of” collection, but as another perspective on what articles attracted the most attention in a particular month.
